Hexachlorophene suppresses β-catenin expression by up-regulation of Siah-1 in EBV-infected B lymphoma cells

Cancer Letters

Volumn 276, Issue 2, 2009, Pages 136-142

  Min, Hye Jin ^a   Cho, Il Rae ^a   Srisuttee, Ratakorn ^a   Park, Eun Hee ^a   Cho, Dae Ho ^b   Ahn, Jin Hyun ^c   Lee, Im Soon ^d   Johnston, Randal N ^e   Oh, Sangtaek ^f   Chung, Young Hwa ^a  

^a Pusan National University   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Sungkyunkwan University School of Medicine   (South Korea)

^d Konkuk University   (South Korea)

^e UNIVERSITY OF CALGARY   (Canada)

^f Inje University   (South Korea)

Author keywords

Catenin; Epstein Barr virus; Hexachlorophene; Latent membrane protein (LMP) 1; Siah 1

Indexed keywords

BETA CATENIN; CYCLIN D1; DOXORUBICIN; HEXACHLOROPHENE; LATENT MEMBRANE PROTEIN 1; MYC PROTEIN; PROTEIN P53; SIAH 1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; B CELL LYMPHOMA; CELL CYCLE ARREST; CELL GROWTH; CONTROLLED STUDY; EPSTEIN BARR VIRUS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; VIRUS INFECTION;

BETA CATENIN; CELL LINE, TUMOR; HERPESVIRUS 4, HUMAN; HEXACHLOROPHENE; HUMANS; LYMPHOMA, B-CELL; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES; UP-REGULATION; VIRAL MATRIX PROTEINS;

HUMAN HERPESVIRUS 4;

EID: 60849103069     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2008.10.041     Document Type: Article

References (41)

1. Peifer M., and Polakis P. Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 287 (2000) 1606-1609
2. Huelsken J., and Birchmeier W. New aspects of Wnt signaling pathways in higher vertebrates. Curr. Opin. Genet. Dev. 11 (2001) 547-553
3. Giles R.H., van Es J.H., and Clevers H. Caught up in a Wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 1653 (2003) 1-24
4. Polakis P. Casein kinase 1: a Wnt'er of disconnect. Curr. Biol. 12 (2002) R499-R501
5. Liu J., Stevens J., Rote C.A., Yost H.J., Hu Y., Neufeld K.L., White R.L., and Matsunami N. Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol. Cell 7 (2001) 927-936
6. Hart M.J., de los Santos R., Albert I.N., Rubinfeld B., and Polakis P. Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr. Biol. 8 (1998) 573-581
7. Kishida S., Yamamoto H., Ikeda S., Kishida M., Sakamoto I., Koyama S., and Kikuchi A. Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin. J. Biol. Chem. 273 (1998) 10823-10826
8. Aberle H., Bauer A., Stappert J., Kispert A., and Kemler R. Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 16 (1997) 3797-3804
9. Moorthy R.K., and Thorley-Lawson D.A. All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of rat-1 fibroblasts. J. Virol. 67 (1993) 1638-1646
10. Kulwichit W., Edwards R.H., Davenport E.M., Baskar J.F., Godfrey V., and Raab-Traub N. Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice. Proc. Natl. Acad. Sci. USA 95 (1998) 11963-11968
11. Kondo S., Wakisaka N., Schell M.J., Horikawa T., Sheen T.S., Sato H., Furukawa M., Pagano J.S., and Yoshizaki T. Epstein-Barr virus latent membrane protein 1 induces the matrix metalloproteinase-1 promoter via an Ets binding site formed by a single nucleotide polymorphism: enhanced susceptibility to nasopharyngeal carcinoma. Int. J. Cancer 115 (2005) 368-376
12. Uchida J., Yasui T., Takaoka-Shichijo Y., Muraoka M., Kulwichit W., Raab-Traub N., and Kikutani H. Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses. Science 286 (1999) 300-303
13. Luftig M., Prinarakis E., Yasui T., Tsichritzis T., Cahir-McFarland E., Inoue J., Nakano H., Mak T.W., Yeh W.C., Li X., Akira S., Suzuki N., Suzuki S., Mosialos G., and Kieff E. Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6. Proc. Natl. Acad. Sci. USA 100 (2003) 15595-15600
14. Gires O., Kohlhuber F., Kilger E., Baumann M., Kieser A., Kaiser C., Zeidler R., Scheffer B., Ueffing M., and Hammerschmidt W. Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins. EMBO J. 18 (1999) 3064-3073
15. Jang K.L., Shackelford J., Seo S.Y., and Pagano J.S. Up-regulation of beta-catenin by a viral oncogene correlates with inhibition of the seven in absentia homolog 1 in B lymphoma cells. Proc. Natl. Acad. Sci. USA 102 (2005) 18431-18486
16. Jungermann E. Soap bacteriostats. J. Am. Oil Chem. Soc. 45 (1968) 345-350
17. Heath R.J., Li J., Roland G.E., and Rock C.O. Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene. J. Biol. Chem. 275 (2000) 4654-4659
18. Hsu J.T., Kuo C.J., Hsieh H.P., Wang Y.C., Huang K.K., Lin C.P., Huang P.F., Chen X., and Liang P.H. Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV. FEBS Lett. 574 (2004) 116-120
19. Park S., Gwak J., Cho M., Song T., Won J., Kim D.E., Shin J.G., and Oh S. Hexachlorophene inhibits Wnt/beta-catenin pathway by promoting Siah-mediated beta-catenin degradation. Mol. Pharmacol. 70 (2006) 960-966
20. Choi S.H., Jin S.E., Lee M.K., Lim S.J., Park J.S., Kim B.G., Ahn W.S., and Kim C.K. Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells. Eur. J. Pharm. Biopharm. (2007)
21. Habelhah H., Takahashi S., Cho S.G., Kadoya T., Watanabe T., and Ronai Z. Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. EMBO J. 23 (2004) 322-332
22. van de Wetering M., Oosterwegel M., Dooijes D., and Clevers H. Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box. EMBO J. 10 (1991) 123-132
23. Yeh P.Y., Chuang S.E., Yeh K.H., Song Y.C., Chang L.L., and Cheng A.L. Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death. Oncogene 23 (2004) 3580-3588
24. Ju J., Schmitz J.C., Song B., Kudo K., and Chu E. Regulation of p53 expression in response to 5-fluorouracil in human cancer RKO cells. Clin. Cancer Res. 13 (2007) 4245-4251
25. Radu A., Neubauer V., Akagi T., Hanafusa H., and Georgescu M.M. PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1. Mol. Cell. Biol. 23 (2003) 6139-6149
26. Sumrejkanchanakij P., Tamamori-Adachi M., Matsunaga Y., Eto K., and Ikeda M.A. Role of cyclin D1 cytoplasmic sequestration in the survival of postmitotic neurons. Oncogene 22 (2003) 8723-8730
27. Gregory M.A., Qi Y., and Hann S.R. Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J. Biol. Chem. 278 (2003) 51606-51612
28. Tamamori-Adachi M., Ito H., Sumrejkanchanakij P., Adachi S., Hiroe M., Shimizu M., Kawauchi J., Sunamori M., Marumo F., Kitajima S., and Ikeda M.A. Critical role of cyclin D1 nuclear import in cardiomyocyte proliferation. Circ. Res. 92 (2003) e12-e19
29. Huang W.S., Wang J.P., Wang T., Fang J.Y., Lan P., and Ma J.P. ShRNA-mediated gene silencing of beta-catenin inhibits growth of human colon cancer cells. World J. Gastroenterol. 13 (2007) 6581-6587
30. Wieczorek M., Paczkowska A., Guzenda P., Majorek M., Bednarek A.K., and Lamparska-Przybysz M. Silencing of Wnt-1 by siRNA induces apoptosis of MCF-7 human breast cancer cells. Cancer Biol. Ther. 7 (2008) 268-274
31. Pannequin J., Delaunay N., Buchert M., Surrel F., Bourgaux J.F., Ryan J., Boireau S., Coelho J., Pelegrin A., Singh P., Shulkes A., Yim M., Baldwin G.S., Pignodel C., Lambeau G., Jay P., Joubert D., and Hollande F. Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors. Gastroenterology 133 (2007) 1554-1568
32. Fearnhead N.S., Britton M.P., and Bodmer W.F. The ABC of APC. Hum. Mol. Genet. 10 (2001) 721-733
33. Karim R., Tse G., Putti T., Scolyer R., and Lee S. The significance of the Wnt pathway in the pathology of human cancers. Pathology 36 (2004) 120-128
34. Fujimuro M., Wu F.Y., ApRhys C., Kajumbula H., Young D.B., Hayward G.S., and Hayward S.D. A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency. Nat. Med. 9 (2003) 300-306
35. Fujimuro M., Liu J., Zhu J., Yokosawa H., and Hayward S.D. Regulation of the interaction between glycogen synthase kinase 3 and the Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen. J. Virol. 79 (2005) 10429-10441
36. Hu G., and Fearon E.R. Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins. Mol. Cell. Biol. 19 (1999) 724-732
37. Fiucci G., Beaucourt S., Duflaut D., Lespagnol A., Stumptner-Cuvelette P., Geant A., Buchwalter G., Tuynder M., Susini L., Lassalle J.M., Wasylyk C., Wasylyk B., Oren M., Amson R., and Telerman A. Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter. Proc. Natl. Acad. Sci. USA 101 (2004) 3510-3515
38. Takahashi M., Tsunoda T., Seiki M., Nakamura Y., and Furukawa Y. Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers. Oncogene 21 (2002) 5861-5867
39. Topol L., Jiang X., Choi H., Garrett-Beal L., Carolan P.J., and Yang Y. Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation. J. Cell Biol. 162 (2003) 899-908
40. Emami K.H., Nguyen C., Ma H., Kim D.H., Jeong K.W., Eguchi M., Moon R.T., Teo J.L., Kim H.Y., Moon S.H., Ha J.R., and Kahn M. A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proc. Natl. Acad. Sci. USA 101 (2004) 12682-12687
41. Lepourcelet M., Chen Y.N., France D.S., Wang H., Crews P., Petersen F., Bruseo C., Wood A.W., and Shivdasani R.A. Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex. Cancer Cell 5 (2004) 91-102