Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 5, 2009, Pages 1626-1631

  Hu, Hongzhen ^a   Grandl, Jörg ^b   Bandell, Michael ^a   Petrus, Matt ^a   Patapoutian, Ardem ^a,b  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; AMINO ACID; ASPARAGINE; CALCIUM; CAMPHOR; HISTIDINE; TRANSIENT RECEPTOR POTENTIAL CHANNEL; VANILLOID RECEPTOR 3; VANILLOID RECEPTOR 4; 2-AMINOETHYL DIPHENYLBORINATE; BORON DERIVATIVE; PRIMER DNA; TRPV3 PROTEIN, MOUSE; TRPV4 PROTEIN, MOUSE; VANILLOID RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CHANNEL GATING; CHICKEN; CLONE; DOG; EMBRYO; EXTRACELLULAR CALCIUM; FROG; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; MOUSE; MUTAGENESIS; MUTATION; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; RECEPTOR POTENTIAL; TEMPERATURE SENSITIVITY; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE; CHEMISTRY; DRUG EFFECT; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; TEMPERATURE;

ANURA; CANIS FAMILIARIS; DRYOBALANOPS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BASE SEQUENCE; BORON COMPOUNDS; CALCIUM; CELL LINE; DNA PRIMERS; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE; TRPV CATION CHANNELS;

EID: 60849098730     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0812209106     Document Type: Article

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