Elastin insufficiency predisposes to elevated pulmonary circulatory pressures through changes in elastic artery structure

Journal of Applied Physiology

Volumn 105, Issue 5, 2008, Pages 1610-1619

  Shifren, Adrian ^a   Durmowicz, Anthony G ^a   Knutsen, Russell H ^a   Faury, Gilles ^b   Mecham, Robert P ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIV GRENOBLE ALPES   (France)

Author keywords

Elastin; Mechanics; Pulmonary hypertension; Remodeling

Indexed keywords

ELASTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA SUPRAVALVULAR STENOSIS; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CATHETERIZATION; CONTROLLED STUDY; FEMALE; HEART RIGHT VENTRICLE HYPERTROPHY; HYPOXIA; KNOCKOUT MOUSE; LUNG ARTERY; LUNG ARTERY PRESSURE; LUNG CIRCULATION; LUNG PRESSURE; MALE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; STENOSIS; TRANSGENIC MOUSE; WILD TYPE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BLOOD PRESSURE; ELASTIN; FEMALE; HYPERTENSION, PULMONARY; HYPERTROPHY, RIGHT VENTRICULAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PULMONARY ARTERY; PULMONARY CIRCULATION; STRESS, MECHANICAL; VENTRICULAR FUNCTION, RIGHT; VENTRICULAR PRESSURE;

EID: 57349156578     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.90563.2008     Document Type: Article

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