Direct activation of PDE5 by cGMP: Long-term effects within NO/cGMP signaling

Journal of Cell Biology

Volumn 160, Issue 5, 2003, Pages 719-727

  Mullershausen, Florian ^a   Friebe, Andreas ^a   Feil, Robert ^b   Thompson, W Joseph ^c,d   Hofmann, Franz ^b   Koesling, Doris ^a,e  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^d Cell Pathways Inc   (United States)

^e MA N1/43   (Germany)

Author keywords

cGMP dependent protein kinase; Cyclic GMP; GAF domain; Guanylyl cyclase; Platelets

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GUANYLATE CYCLASE; NITRIC OXIDE; PHOSPHODIESTERASE; PHOSPHODIESTERASE V; UNCLASSIFIED DRUG; VASODILATOR STIMULATED PHOSPHOPROTEIN;

ARTICLE; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DOMAIN; THROMBOCYTE;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANIMALS; BINDING SITES; BLOOD PLATELETS; CELL ADHESION MOLECULES; CELLS, CULTURED; CYCLIC GMP; CYCLIC GMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; FEEDBACK, BIOCHEMICAL; FEMALE; FREE RADICAL SCAVENGERS; GUANYLATE CYCLASE; HUMANS; MALE; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; NITRIC OXIDE; NITRIC OXIDE DONORS; PHOSPHOPROTEINS; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 0037416169     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200211041     Document Type: Article

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