메뉴 건너뛰기




Volumn 9, Issue , 2008, Pages

IFN-γ, IL-4 and IL-13 modulate responsiveness of human airway smooth muscle cells to IL-13

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CCL11 PROTEIN, HUMAN; EOTAXIN; GAMMA INTERFERON; HISTAMINE; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 13 RECEPTOR ALPHA2; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; MESSENGER RNA; SOCS1 PROTEIN, HUMAN; SOCS3 PROTEIN, HUMAN; STAT6 PROTEIN; STAT6 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

EID: 60549095668     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-9-84     Document Type: Article
Times cited : (32)

References (48)
  • 1
    • 0030922389 scopus 로고    scopus 로고
    • Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
    • 10.1016/S0091-6749(97)70028-9, 9155833
    • Humbert M, Durham SR, Kimmitt P, Powell N, Assoufi B, Pfister R, Menz G, Kay AB, Corrigan CJ. Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma. J Allergy Clin Immunol 1997, 99:657-665. 10.1016/S0091-6749(97)70028-9, 9155833.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 657-665
    • Humbert, M.1    Durham, S.R.2    Kimmitt, P.3    Powell, N.4    Assoufi, B.5    Pfister, R.6    Menz, G.7    Kay, A.B.8    Corrigan, C.J.9
  • 4
    • 0031918920 scopus 로고    scopus 로고
    • Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice
    • Hogan SP, Koskinen A, Matthaei KI, Young IG, Foster PS. Interleukin-5-producing CD4+ T cells play a pivotal role in aeroallergen-induced eosinophilia, bronchial hyperreactivity, and lung damage in mice. Am J Respir Crit Care Med 1998, 157:210-218.
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 210-218
    • Hogan, S.P.1    Koskinen, A.2    Matthaei, K.I.3    Young, I.G.4    Foster, P.S.5
  • 6
    • 0032531571 scopus 로고    scopus 로고
    • IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells
    • Cohn L, Tepper JS, Bottomly K. IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells. J Immunol 1998, 161:3813-3816.
    • (1998) J Immunol , vol.161 , pp. 3813-3816
    • Cohn, L.1    Tepper, J.S.2    Bottomly, K.3
  • 7
    • 0030689729 scopus 로고    scopus 로고
    • Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production
    • 2199146, 9362533, 10.1084/jem.186.10.1737
    • Cohn L, Homer RJ, Marinov A, Rankin J, Bottomly K. Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J Exp Med 1997, 186:1737-1747. 2199146, 9362533, 10.1084/jem.186.10.1737.
    • (1997) J Exp Med , vol.186 , pp. 1737-1747
    • Cohn, L.1    Homer, R.J.2    Marinov, A.3    Rankin, J.4    Bottomly, K.5
  • 8
    • 0033560126 scopus 로고    scopus 로고
    • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
    • 408149, 10079098, 10.1172/JCI5909
    • Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999, 103:779-788. 408149, 10079098, 10.1172/JCI5909.
    • (1999) J Clin Invest , vol.103 , pp. 779-788
    • Zhu, Z.1    Homer, R.J.2    Wang, Z.3    Chen, Q.4    Geba, G.P.5    Wang, J.6    Zhang, Y.7    Elias, J.A.8
  • 9
    • 13544271151 scopus 로고    scopus 로고
    • IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling
    • Chen Q, Rabach L, Noble P, Zheng T, Lee CG, Homer RJ, Elias JA. IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol 2005, 174:2305-2313.
    • (2005) J Immunol , vol.174 , pp. 2305-2313
    • Chen, Q.1    Rabach, L.2    Noble, P.3    Zheng, T.4    Lee, C.G.5    Homer, R.J.6    Elias, J.A.7
  • 11
    • 0037102302 scopus 로고    scopus 로고
    • Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice
    • 10.1164/rccm.200202-095OC, 12186819
    • Yoshida M, Leigh R, Matsumoto K, Wattie J, Ellis R, O'Byrne PM, Inman MD. Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice. Am J Respir Crit Care Med 2002, 166:451-456. 10.1164/rccm.200202-095OC, 12186819.
    • (2002) Am J Respir Crit Care Med , vol.166 , pp. 451-456
    • Yoshida, M.1    Leigh, R.2    Matsumoto, K.3    Wattie, J.4    Ellis, R.5    O'Byrne, P.M.6    Inman, M.D.7
  • 12
    • 0037393323 scopus 로고    scopus 로고
    • IL-13 receptors and signaling pathways: an evolving web
    • 10.1067/mai.2003.1333, 12704343
    • Hershey GK. IL-13 receptors and signaling pathways: an evolving web. J Allergy Clin Immunol 2003, 111:677-690. 10.1067/mai.2003.1333, 12704343.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 677-690
    • Hershey, G.K.1
  • 13
    • 0032536837 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production
    • 2212182, 9500796, 10.1084/jem.187.6.939
    • Kuperman D, Schofield B, Wills-Karp M, Grusby MJ. Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production. J Exp Med 1998, 187:939-948. 2212182, 9500796, 10.1084/jem.187.6.939.
    • (1998) J Exp Med , vol.187 , pp. 939-948
    • Kuperman, D.1    Schofield, B.2    Wills-Karp, M.3    Grusby, M.J.4
  • 14
    • 0032828226 scopus 로고    scopus 로고
    • The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5
    • Tomkinson A, Kanehiro A, Rabinovitch N, Joetham A, Cieslewicz G, Gelfand EW. The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5. Am J Respir Crit Care Med 1999, 160:1283-1291.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1283-1291
    • Tomkinson, A.1    Kanehiro, A.2    Rabinovitch, N.3    Joetham, A.4    Cieslewicz, G.5    Gelfand, E.W.6
  • 15
    • 0032482159 scopus 로고    scopus 로고
    • Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
    • 2212260, 9565645, 10.1084/jem.187.9.1537
    • Akimoto T, Numata F, Tamura M, Takata Y, Higashida N, Takashi T, Takeda K, Akira S. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. J Exp Med 1998, 187:1537-1542. 2212260, 9565645, 10.1084/jem.187.9.1537.
    • (1998) J Exp Med , vol.187 , pp. 1537-1542
    • Akimoto, T.1    Numata, F.2    Tamura, M.3    Takata, Y.4    Higashida, N.5    Takashi, T.6    Takeda, K.7    Akira, S.8
  • 19
    • 0036168305 scopus 로고    scopus 로고
    • IL-13R(alpha)2, a decoy receptor for IL-13 acts as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells
    • Rahaman SO, Sharma P, Harbor PC, Aman MJ, Vogelbaum MA, Haque SJ. IL-13R(alpha)2, a decoy receptor for IL-13 acts as an inhibitor of IL-4-dependent signal transduction in glioblastoma cells. Cancer Res 2002, 62:1103-1109.
    • (2002) Cancer Res , vol.62 , pp. 1103-1109
    • Rahaman, S.O.1    Sharma, P.2    Harbor, P.C.3    Aman, M.J.4    Vogelbaum, M.A.5    Haque, S.J.6
  • 20
    • 0037155828 scopus 로고    scopus 로고
    • A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma
    • 10.1074/jbc.M108109200, 11786536
    • Daines MO, Hershey GK. A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma. J Biol Chem 2002, 277:10387-10393. 10.1074/jbc.M108109200, 11786536.
    • (2002) J Biol Chem , vol.277 , pp. 10387-10393
    • Daines, M.O.1    Hershey, G.K.2
  • 21
    • 30044449492 scopus 로고    scopus 로고
    • IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis
    • 10.1038/nm1332, 16327802
    • Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A. IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis. Nat Med 2006, 12:99-106. 10.1038/nm1332, 16327802.
    • (2006) Nat Med , vol.12 , pp. 99-106
    • Fichtner-Feigl, S.1    Strober, W.2    Kawakami, K.3    Puri, R.K.4    Kitani, A.5
  • 22
    • 0030953977 scopus 로고    scopus 로고
    • Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins
    • 507949, 9077543, 10.1172/JCI119292
    • Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest 1997, 99:1329-1339. 507949, 9077543, 10.1172/JCI119292.
    • (1997) J Clin Invest , vol.99 , pp. 1329-1339
    • Hogan, S.P.1    Mould, A.2    Kikutani, H.3    Ramsay, A.J.4    Foster, P.S.5
  • 23
    • 1642545168 scopus 로고    scopus 로고
    • IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle
    • 1574143, 14597600, 10.1038/sj.bjp.0705558
    • Tliba O, Deshpande D, Chen H, Van Besien C, Kannan M, Panettieri RA, Amrani Y. IL-13 enhances agonist-evoked calcium signals and contractile responses in airway smooth muscle. Br J Pharmacol 2003, 140:1159-1162. 1574143, 14597600, 10.1038/sj.bjp.0705558.
    • (2003) Br J Pharmacol , vol.140 , pp. 1159-1162
    • Tliba, O.1    Deshpande, D.2    Chen, H.3    Van Besien, C.4    Kannan, M.5    Panettieri, R.A.6    Amrani, Y.7
  • 24
    • 0038404961 scopus 로고    scopus 로고
    • CysLT1 receptor upregulation by TGF-beta and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4
    • 10.1067/mai.2003.1451, 12743568
    • Espinosa K, Bosse Y, Stankova J, Rola-Pleszczynski M. CysLT1 receptor upregulation by TGF-beta and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4. J Allergy Clin Immunol 2003, 111:1032-1040. 10.1067/mai.2003.1451, 12743568.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 1032-1040
    • Espinosa, K.1    Bosse, Y.2    Stankova, J.3    Rola-Pleszczynski, M.4
  • 27
    • 4944253264 scopus 로고    scopus 로고
    • TGF-beta differentially regulates TH2 cytokine-induced eotaxin and eotaxin-3 release by human airway smooth muscle cells
    • 10.1016/j.jaci.2004.06.037, 15480317
    • Zuyderduyn S, Hiemstra PS, Rabe KF. TGF-beta differentially regulates TH2 cytokine-induced eotaxin and eotaxin-3 release by human airway smooth muscle cells. J Allergy Clin Immunol 2004, 114:791-798. 10.1016/j.jaci.2004.06.037, 15480317.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 791-798
    • Zuyderduyn, S.1    Hiemstra, P.S.2    Rabe, K.F.3
  • 28
    • 0036049786 scopus 로고    scopus 로고
    • Effects of cytokines on contractile and dilator responses of airway smooth muscle
    • 10.1046/j.1440-1681.2002.03756.x, 12207563
    • Shore SA, Moore PE. Effects of cytokines on contractile and dilator responses of airway smooth muscle. Clin Exp Pharmacol Physiol 2002, 29:859-866. 10.1046/j.1440-1681.2002.03756.x, 12207563.
    • (2002) Clin Exp Pharmacol Physiol , vol.29 , pp. 859-866
    • Shore, S.A.1    Moore, P.E.2
  • 29
    • 1442325348 scopus 로고    scopus 로고
    • Signaling pathways regulating interleukin-13-stimulated chemokine release from airway smooth muscle
    • 10.1164/rccm.200307-888OC, 14670803
    • Peng Q, Matsuda T, Hirst SJ. Signaling pathways regulating interleukin-13-stimulated chemokine release from airway smooth muscle. Am J Respir Crit Care Med 2004, 169:596-603. 10.1164/rccm.200307-888OC, 14670803.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 596-603
    • Peng, Q.1    Matsuda, T.2    Hirst, S.J.3
  • 30
  • 31
    • 0021895138 scopus 로고
    • A new generation of Ca2+ indicators with greatly improved fluorescence properties
    • Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985, 260:3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 32
    • 33847081534 scopus 로고    scopus 로고
    • IL-13Ralpha2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca+ signaling
    • 10.1159/000097022, 17106207
    • Kellner J, Gamarra F, Welsch U, Jorres RA, Huber RM, Bergner A. IL-13Ralpha2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca+ signaling. Int Arch Allergy Immunol 2007, 142:199-210. 10.1159/000097022, 17106207.
    • (2007) Int Arch Allergy Immunol , vol.142 , pp. 199-210
    • Kellner, J.1    Gamarra, F.2    Welsch, U.3    Jorres, R.A.4    Huber, R.M.5    Bergner, A.6
  • 34
    • 0037090417 scopus 로고    scopus 로고
    • Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain
    • Hirst SJ, Hallsworth MP, Peng Q, Lee TH. Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain. Am J Respir Crit Care Med 2002, 165:1161-1171.
    • (2002) Am J Respir Crit Care Med , vol.165 , pp. 1161-1171
    • Hirst, S.J.1    Hallsworth, M.P.2    Peng, Q.3    Lee, T.H.4
  • 35
    • 4944242074 scopus 로고    scopus 로고
    • Upregulation of interleukin-4 receptor by interferon-gamma: enhanced interleukin-4-induced eotaxin-3 production in airway epithelium
    • 10.1165/rcmb.2004-0128OC, 15231490
    • Yamamoto S, Kobayashi I, Tsuji K, Nishi N, Muro E, Miyazaki M, Zaitsu M, Inada S, Ichimaru T, Hamasaki Y. Upregulation of interleukin-4 receptor by interferon-gamma: enhanced interleukin-4-induced eotaxin-3 production in airway epithelium. Am J Respir Cell Mol Biol 2004, 31:456-462. 10.1165/rcmb.2004-0128OC, 15231490.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 456-462
    • Yamamoto, S.1    Kobayashi, I.2    Tsuji, K.3    Nishi, N.4    Muro, E.5    Miyazaki, M.6    Zaitsu, M.7    Inada, S.8    Ichimaru, T.9    Hamasaki, Y.10
  • 36
    • 0032850616 scopus 로고    scopus 로고
    • Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression
    • 17963, 10485906, 10.1073/pnas.96.19.10800
    • Dickensheets HL, Venkataraman C, Schindler U, Donnelly RP. Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression. Proc Natl Acad Sci USA 1999, 96:10800-10805. 17963, 10485906, 10.1073/pnas.96.19.10800.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10800-10805
    • Dickensheets, H.L.1    Venkataraman, C.2    Schindler, U.3    Donnelly, R.P.4
  • 37
  • 39
    • 12444342977 scopus 로고    scopus 로고
    • IFN-gamma suppresses STAT6 phosphorylation by inhibiting its recruitment to the IL-4 receptor
    • Huang Z, Xin J, Coleman J, Huang H. IFN-gamma suppresses STAT6 phosphorylation by inhibiting its recruitment to the IL-4 receptor. J Immunol 2005, 174:1332-1337.
    • (2005) J Immunol , vol.174 , pp. 1332-1337
    • Huang, Z.1    Xin, J.2    Coleman, J.3    Huang, H.4
  • 40
    • 0034142220 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor alpha-chain
    • Huang H, Paul WE. Protein tyrosine phosphatase activity is required for IL-4 induction of IL-4 receptor alpha-chain. J Immunol 2000, 164:1211-1215.
    • (2000) J Immunol , vol.164 , pp. 1211-1215
    • Huang, H.1    Paul, W.E.2
  • 41
    • 0011124007 scopus 로고
    • Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression
    • 282399, 3263648, 10.1073/pnas.85.21.8221
    • Ohara J, Paul WE. Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression. Proc Natl Acad Sci USA 1988, 85:8221-8225. 282399, 3263648, 10.1073/pnas.85.21.8221.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8221-8225
    • Ohara, J.1    Paul, W.E.2
  • 42
    • 25444487989 scopus 로고    scopus 로고
    • The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells
    • 548512, 15661077, 10.1186/1465-9921-6-9
    • Syed F, Panettieri RA, Tliba O, Huang C, Li K, Bracht M, Amegadzie B, Griswold D, Li L, Amrani Y. The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells. Respir Res 2005, 6:9. 548512, 15661077, 10.1186/1465-9921-6-9.
    • (2005) Respir Res , vol.6 , pp. 9
    • Syed, F.1    Panettieri, R.A.2    Tliba, O.3    Huang, C.4    Li, K.5    Bracht, M.6    Amegadzie, B.7    Griswold, D.8    Li, L.9    Amrani, Y.10
  • 43
    • 0037393502 scopus 로고    scopus 로고
    • Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro
    • 10.1067/mai.2003.1383, 12704349
    • Zheng T, Zhu Z, Liu W, Lee CG, Chen Q, Homer RJ, Elias JA. Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro. J Allergy Clin Immunol 2003, 111:720-728. 10.1067/mai.2003.1383, 12704349.
    • (2003) J Allergy Clin Immunol , vol.111 , pp. 720-728
    • Zheng, T.1    Zhu, Z.2    Liu, W.3    Lee, C.G.4    Chen, Q.5    Homer, R.J.6    Elias, J.A.7
  • 44
    • 10744229896 scopus 로고    scopus 로고
    • The negative-feedback regulation of the IL-13 signal by the IL-13 receptor alpha2 chain in bronchial epithelial cells
    • 10.1016/j.cyto.2003.08.006, 14609571
    • Yasunaga S, Yuyama N, Arima K, Tanaka H, Toda S, Maeda M, Matsui K, Goda C, Yang Q, Sugita Y, Nagai H, Izuhara K. The negative-feedback regulation of the IL-13 signal by the IL-13 receptor alpha2 chain in bronchial epithelial cells. Cytokine 2003, 24:293-303. 10.1016/j.cyto.2003.08.006, 14609571.
    • (2003) Cytokine , vol.24 , pp. 293-303
    • Yasunaga, S.1    Yuyama, N.2    Arima, K.3    Tanaka, H.4    Toda, S.5    Maeda, M.6    Matsui, K.7    Goda, C.8    Yang, Q.9    Sugita, Y.10    Nagai, H.11    Izuhara, K.12
  • 46
    • 0033120880 scopus 로고    scopus 로고
    • Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
    • Losman JA, Chen XP, Hilton D, Rothman P. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J Immunol 1999, 162:3770-3774.
    • (1999) J Immunol , vol.162 , pp. 3770-3774
    • Losman, J.A.1    Chen, X.P.2    Hilton, D.3    Rothman, P.4
  • 47
    • 10344262891 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells
    • 10.1016/j.molimm.2004.09.004, 15589317
    • Hebenstreit D, Luft P, Schmiedlechner A, Duschl A, Horejs-Hoeck J. SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells. Mol Immunol 2005, 42:295-303. 10.1016/j.molimm.2004.09.004, 15589317.
    • (2005) Mol Immunol , vol.42 , pp. 295-303
    • Hebenstreit, D.1    Luft, P.2    Schmiedlechner, A.3    Duschl, A.4    Horejs-Hoeck, J.5
  • 48
    • 33846523494 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling
    • 10.1038/sj.gene.6364352, 17093501
    • Dickensheets H, Vazquez N, Sheikh F, Gingras S, Murray PJ, Ryan JJ, Donnelly RP. Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling. Genes Immun 2007, 8:21-27. 10.1038/sj.gene.6364352, 17093501.
    • (2007) Genes Immun , vol.8 , pp. 21-27
    • Dickensheets, H.1    Vazquez, N.2    Sheikh, F.3    Gingras, S.4    Murray, P.J.5    Ryan, J.J.6    Donnelly, R.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.