Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis

Oncogene

Volumn 28, Issue 7, 2009, Pages 950-960

  Kim, D J ^a   Angel, J M ^a   Sano, S ^b   DiGiovanni, J ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Skin carcinogenesis; Stat3; UVB

Indexed keywords

CYCLIN D1; PROTEIN BCL XL; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOASSAY; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; EPIDERMIS CELL; EPIDERMIS HYPERPLASIA; GENE EXPRESSION; HAIR FOLLICLE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; SKIN CARCINOGENESIS; TRANSGENIC MOUSE; ULTRAVIOLET B RADIATION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CYCLIN D1; CYCLINS; DISEASE MODELS, ANIMAL; EPIDERMIS; IMMUNOENZYME TECHNIQUES; INTEGRASES; KERATINOCYTES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASMS, RADIATION-INDUCED; SKIN NEOPLASMS; STAT3 TRANSCRIPTION FACTOR; ULTRAVIOLET RAYS;

MUS; MUS MUSCULUS;

EID: 60549086385     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.453     Document Type: Article

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