메뉴 건너뛰기




Volumn 36, Issue 4, 1998, Pages 249-278

The FEMA GRAS assessment of lactones used as flavour ingredients

Author keywords

[No Author keywords available]

Indexed keywords

FLAVORING AGENT; GAMMA BUTYROLACTONE; LACTONE;

EID: 0032489789     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(97)00163-4     Document Type: Article
Times cited : (87)

References (181)
  • 3
    • 0016703454 scopus 로고
    • The metabolism of 2-ethyl-1-hexanol in rats
    • Albro P. W. (1975) The metabolism of 2-ethyl-1-hexanol in rats. Xenobiotica 5, 625-636.
    • (1975) Xenobiotica , vol.5 , pp. 625-636
    • Albro, P.W.1
  • 4
    • 0018894476 scopus 로고
    • Absorption of sodium γ-hydroxybutyric acid and its prodrug γ-butyrolactone: Relationship between in vitro transport and in vivo absorption
    • Arena C. and Fung H. L. (1980) Absorption of sodium γ-hydroxybutyric acid and its prodrug γ-butyrolactone: relationship between in vitro transport and in vivo absorption. Journal of Pharmaceutical Sciences 69, 356-358.
    • (1980) Journal of Pharmaceutical Sciences , vol.69 , pp. 356-358
    • Arena, C.1    Fung, H.L.2
  • 5
    • 0028174135 scopus 로고
    • Prediction of rodent carcinogenicity for 44 chemicals: Results
    • Ashby J. and Tenant R. W. (1991) Prediction of rodent carcinogenicity for 44 chemicals: Results. Mutagenesis 9, 7-15.
    • (1991) Mutagenesis , vol.9 , pp. 7-15
    • Ashby, J.1    Tenant, R.W.2
  • 6
    • 0000915507 scopus 로고
    • Study of 42 coded compounds with the Salmonella/mammalian microsome assay
    • Baker R. S. U. and Bonin A. M. (1981) Study of 42 coded compounds with the Salmonella/mammalian microsome assay. Progress in Mutation Research 1, 249-260.
    • (1981) Progress in Mutation Research , vol.1 , pp. 249-260
    • Baker, R.S.U.1    Bonin, A.M.2
  • 7
    • 0001521029 scopus 로고
    • Where we stand concerning the evaluation of flavouring substances from the viewpoint of health
    • Bar V. F. and Griepentrog F. (1967) Where we stand concerning the evaluation of flavouring substances from the viewpoint of health. Medizin Ernahrung 8, 244-251.
    • (1967) Medizin Ernahrung , vol.8 , pp. 244-251
    • Bar, V.F.1    Griepentrog, F.2
  • 9
    • 0000581642 scopus 로고
    • Gamma-hydroxybutyrate, a normal brain metabolite
    • Bessman S. P. and Fishbein W. N. (1963) Gamma-hydroxybutyrate, a normal brain metabolite. Nature 200, 1207-1208.
    • (1963) Nature , vol.200 , pp. 1207-1208
    • Bessman, S.P.1    Fishbein, W.N.2
  • 11
    • 0010461941 scopus 로고
    • Study number 84-302. Unpublished report to RIFM
    • Bioassay Systems Corporation (1984) Single dose oral toxicity tests. Study number 84-302. Unpublished report to RIFM.
    • (1984) Single Dose Oral Toxicity Tests
  • 13
    • 0014768820 scopus 로고
    • The effect of carbonyl compounds on rat liver glutathione levels
    • Boyland E. and Chasseaud L. (1970) The effect of carbonyl compounds on rat liver glutathione levels. Biochemical Pharmacology 19, 1528-1533.
    • (1970) Biochemical Pharmacology , vol.19 , pp. 1528-1533
    • Boyland, E.1    Chasseaud, L.2
  • 14
    • 0017371203 scopus 로고
    • The metabolism of cyclohexanecarboxylic acid in the rat
    • Brewster D., Jones R. S. and Parke D. V. (1977a) The metabolism of cyclohexanecarboxylic acid in the rat. Biochemical Journal 164, 595-600.
    • (1977) Biochemical Journal , vol.164 , pp. 595-600
    • Brewster, D.1    Jones, R.S.2    Parke, D.V.3
  • 15
    • 0017749051 scopus 로고
    • The metabolism of cyclohexanecarboxylic acid in the isolated perfused rat liver
    • Brewster D., Jones R. S. and Parke D. V. (1977b) The metabolism of cyclohexanecarboxylic acid in the isolated perfused rat liver. Xenobiotica 7, 601-609.
    • (1977) Xenobiotica , vol.7 , pp. 601-609
    • Brewster, D.1    Jones, R.S.2    Parke, D.V.3
  • 16
    • 0001623074 scopus 로고
    • Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay with preincubation
    • Brooks T. M. and Dean B. J. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay with preincubation. Progress in Mutation Research 1, 261-270.
    • (1981) Progress in Mutation Research , vol.1 , pp. 261-270
    • Brooks, T.M.1    Dean, B.J.2
  • 17
    • 0023010822 scopus 로고
    • Genotoxic effects of cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations
    • Brusick D. (1986) Genotoxic effects of cultured mammalian cells produced by low pH treatment conditions and increased ion concentrations. Environmental Mutagenesis 8, 879-886.
    • (1986) Environmental Mutagenesis , vol.8 , pp. 879-886
    • Brusick, D.1
  • 21
    • 0026582870 scopus 로고
    • Comparison of a novel thin-layer chromatographic-nuorescence detection method with a spectronuorimetric method for the determination of 7-hydroxycoumarin in human urine
    • Cholerton S., Idle M. E., Vas A., Gonzalez F. J. and Idle J. R. (1992) Comparison of a novel thin-layer chromatographic-nuorescence detection method with a spectronuorimetric method for the determination of 7-hydroxycoumarin in human urine. Journal of Chromatography 575, 325-330.
    • (1992) Journal of Chromatography , vol.575 , pp. 325-330
    • Cholerton, S.1    Idle, M.E.2    Vas, A.3    Gonzalez, F.J.4    Idle, J.R.5
  • 22
    • 0010499312 scopus 로고
    • Edited by H. Maarse, C. A. Visscher, L. C. Willemsens, L. M. Nijssen and M. H. Boelens. TNO Nutrition and Food Research, Zeist, The Netherlands
    • CIVO-TNO. (1994) Volatile components in food. Supplement 5 to the 6th Edition. Edited by H. Maarse, C. A. Visscher, L. C. Willemsens, L. M. Nijssen and M. H. Boelens. TNO Nutrition and Food Research, Zeist, The Netherlands. .
    • (1994) Volatile Components in Food. Supplement 5 to the 6th Edition
  • 23
    • 0018736331 scopus 로고
    • Critical review of the toxicology of coumarin with special reference to interspecies differences in metabolism and hepatotoxic response and their significance to man
    • Cohen A. J. (1979) Critical review of the toxicology of coumarin with special reference to interspecies differences in metabolism and hepatotoxic response and their significance to man. Food and Cosmetics Toxicology 17, 277-289.
    • (1979) Food and Cosmetics Toxicology , vol.17 , pp. 277-289
    • Cohen, A.J.1
  • 27
    • 0014429121 scopus 로고
    • Reductase for aromatic aldehydes and ketones. Partial purification and properties of a reduced triphosphopyridine nucleotide dependent reductase from rabbit kidney cortex
    • Culp H. W. and McMahon R. E. (1968) Reductase for aromatic aldehydes and ketones. Partial purification and properties of a reduced triphosphopyridine nucleotide dependent reductase from rabbit kidney cortex. Journal of Biological Chemistry 243, 848-852.
    • (1968) Journal of Biological Chemistry , vol.243 , pp. 848-852
    • Culp, H.W.1    McMahon, R.E.2
  • 28
  • 30
    • 0028336635 scopus 로고
    • Metabolism of 2-ethylhexanol administered orally and dermally to the female Fischer 344 rat
    • Deisinger P. J., Boatman R. J. and Guest D. (1994) Metabolism of 2-ethylhexanol administered orally and dermally to the female Fischer 344 rat. Xenobiotica 24, 429-440.
    • (1994) Xenobiotica , vol.24 , pp. 429-440
    • Deisinger, P.J.1    Boatman, R.J.2    Guest, D.3
  • 32
    • 0010501025 scopus 로고
    • Further studies on the carcinogenic action of certain lactones and related substances in the rat and mouse
    • Dickens F. and Jones H. E. (1965) Further studies on the carcinogenic action of certain lactones and related substances in the rat and mouse. British Journal of Cancer 9, 392-403.
    • (1965) British Journal of Cancer , vol.9 , pp. 392-403
    • Dickens, F.1    Jones, H.E.2
  • 34
    • 0018192666 scopus 로고
    • 14C] butyrate by rat brain: Relationship to the krebs cycle and metabolic compartmentation of amino acids
    • 14C] butyrate by rat brain: relationship to the Krebs cycle and metabolic compartmentation of amino acids. Journal of Neurochemistry 30, 1305-1309.
    • (1978) Journal of Neurochemistry , vol.30 , pp. 1305-1309
    • Doherty, J.D.1    Roth, R.H.2
  • 36
    • 0025663358 scopus 로고
    • The pharmacology, metabolism, analysis and applications of coumarin and coumarin-related compounds
    • Egan D., O'Kennedy R., Moran E., Cox D., Prossier E. and Thorne R. D. (1990) The pharmacology, metabolism, analysis and applications of coumarin and coumarin-related compounds. Drug Metabolism Reviews 22, 503-529.
    • (1990) Drug Metabolism Reviews , vol.22 , pp. 503-529
    • Egan, D.1    O'Kennedy, R.2    Moran, E.3    Cox, D.4    Prossier, E.5    Thorne, R.D.6
  • 38
    • 0010461004 scopus 로고
    • Biosynthesis of chiral flavours and aroma compounds in plants and microorganisms
    • Edited by R. Teranishi, R. Buttery and F. Shahidi. ACS Symposium Series 388. American Chemical Society, Washington, DC
    • Engel K-H., Heidlas J., Albrecht W. and Tressl R. (1989) Biosynthesis of chiral flavours and aroma compounds in plants and microorganisms. In Flavour Chemistry, Trends and Developments. Edited by R. Teranishi, R. Buttery and F. Shahidi. ACS Symposium Series 388. American Chemical Society, Washington, DC.
    • (1989) Flavour Chemistry, Trends and Developments
    • Engel, K.-H.1    Heidlas, J.2    Albrecht, W.3    Tressl, R.4
  • 40
    • 0010463345 scopus 로고
    • Unpublished report to RIFM
    • Fassett D. (1961). Unpublished report to RIFM.
    • (1961)
    • Fassett, D.1
  • 41
    • 0001298231 scopus 로고
    • Ketone reductases
    • Edited by W. Jakoby. Academic Press, New York
    • Felsted R. L. and Bachur N. R. (1980) Ketone reductases. In Enzymatic Basis of Detoxification. Edited by W. Jakoby. Vol. I, pp. 281-293. Academic Press, New York.
    • (1980) Enzymatic Basis of Detoxification , vol.1 , pp. 281-293
    • Felsted, R.L.1    Bachur, N.R.2
  • 42
    • 0026593719 scopus 로고
    • Metabolism of coumarin by rat, gerbil and human liver microsomes
    • Fentem J. H. and Fry J. R. (1992) Metabolism of coumarin by rat, gerbil and human liver microsomes. Xenobiotica 22, 357-367.
    • (1992) Xenobiotica , vol.22 , pp. 357-367
    • Fentem, J.H.1    Fry, J.R.2
  • 44
    • 0016236139 scopus 로고
    • The metabolism and biological actions of coumarins
    • Edited by G. P. Ellis and G. B. West. Elsevier, Amsterdam
    • Feuer G. (1974) The metabolism and biological actions of coumarins. In Progress Medicinal Chemistry. Edited by G. P. Ellis and G. B. West. Vol. 10, pp. 85-158. Elsevier, Amsterdam.
    • (1974) Progress Medicinal Chemistry , vol.10 , pp. 85-158
    • Feuer, G.1
  • 47
    • 0014011582 scopus 로고
    • Purification and properties of an enzyme in human blood and rat liver microsomes catalyzing the formation and hydrolysis of γ-lactones. I. Tissue location, stoichiometry, specificity, distinction from esterase
    • Fishbein W. N. and Bessman S. P. (1966) Purification and properties of an enzyme in human blood and rat liver microsomes catalyzing the formation and hydrolysis of γ-lactones. I. Tissue location, stoichiometry, specificity, distinction from esterase. Journal of Biological Chemistry 241, 4835-4841.
    • (1966) Journal of Biological Chemistry , vol.241 , pp. 4835-4841
    • Fishbein, W.N.1    Bessman, S.P.2
  • 50
    • 0028294505 scopus 로고
    • Chemical mutagenesis testing in Drosophila. X. Results of 70 coded chemicals tested for the National Toxicology Program
    • Foureman P., Mason J. M., Valencia R. and Zimmering S. (1994) Chemical mutagenesis testing in Drosophila. X. Results of 70 coded chemicals tested for the National Toxicology Program. Environmental and Molecular Mutagenesis 23, 208-227.
    • (1994) Environmental and Molecular Mutagenesis , vol.23 , pp. 208-227
    • Foureman, P.1    Mason, J.M.2    Valencia, R.3    Zimmering, S.4
  • 53
    • 85008077015 scopus 로고
    • Studies on the metabolism of the naturally occurring coumarins. V. Urinary metabolites of coumarin and dihydrocoumarin
    • Furuya T. (1958) Studies on the metabolism of the naturally occurring coumarins. V. Urinary metabolites of coumarin and dihydrocoumarin. Chemical and Pharmaceutical Bulletin 6, 701-706.
    • (1958) Chemical and Pharmaceutical Bulletin , vol.6 , pp. 701-706
    • Furuya, T.1
  • 55
    • 0000689448 scopus 로고
    • Mutagenic activity of 42 coded compounds in the salmonella/ microsome assay
    • Garner R., Welch A. and Pickering C. (1981) Mutagenic activity of 42 coded compounds in the salmonella/ microsome assay. Progress in Mutation Research 1, 280-284.
    • (1981) Progress in Mutation Research , vol.1 , pp. 280-284
    • Garner, R.1    Welch, A.2    Pickering, C.3
  • 56
    • 0014749597 scopus 로고
    • Relationship between pharmacological effects and blood and brain levels of gamma-butyrolactone and gamma-hydroxybutyrate
    • Guidotti A. and Ballotti P. L. (1970) Relationship between pharmacological effects and blood and brain levels of gamma-butyrolactone and gamma-hydroxybutyrate. Biochemical Pharmacology 19, 884-894.
    • (1970) Biochemical Pharmacology , vol.19 , pp. 884-894
    • Guidotti, A.1    Ballotti, P.L.2
  • 60
    • 0023729293 scopus 로고
    • Micronucleus test in mice on 39 food additives and eight miscellaneous chemicals
    • Hayashi M., Kishi M., Sofuni T. and Ishidate M., Jr (1988) Micronucleus test in mice on 39 food additives and eight miscellaneous chemicals. Food and Chemical Toxicology 26, 487-500.
    • (1988) Food and Chemical Toxicology , vol.26 , pp. 487-500
    • Hayashi, M.1    Kishi, M.2    Sofuni, T.3    Ishidate M., Jr.4
  • 63
  • 65
    • 0001161511 scopus 로고
    • Mutagen testing of a series of paired compounds with the Ames Salmonella testing system
    • Ichinotsubo D., Mower H. and Mandel M. (1981) Mutagen testing of a series of paired compounds with the Ames Salmonella testing system. Progress in Mutation Research 1, 298-301.
    • (1981) Progress in Mutation Research , vol.1 , pp. 298-301
    • Ichinotsubo, D.1    Mower, H.2    Mandel, M.3
  • 67
    • 0010501027 scopus 로고
    • Aldehyde oxidation. III. Succinic semialdehyde dehydrogenase
    • Jakoby W. B. and Scott E. M. (1959) Aldehyde oxidation. III. Succinic semialdehyde dehydrogenase. Journal of Biological Chemistry 234, 937-940.
    • (1959) Journal of Biological Chemistry , vol.234 , pp. 937-940
    • Jakoby, W.B.1    Scott, E.M.2
  • 69
    • 0344394083 scopus 로고
    • Activity of 40 coded compounds in differential inhibition and mitotic crossing-over assays in yeast
    • Kassinova G. V., Kavaltsova S. V., Marfin S. V. and Zakhrov I. A. (1981) Activity of 40 coded compounds in differential inhibition and mitotic crossing-over assays in yeast. Progress in Mutation Research 1, 434-455.
    • (1981) Progress in Mutation Research , vol.1 , pp. 434-455
    • Kassinova, G.V.1    Kavaltsova, S.V.2    Marfin, S.V.3    Zakhrov, I.A.4
  • 70
    • 0010421021 scopus 로고
    • Mutagenic activity of polycyclic aromatic hydrocarbons and other environmental pollutants
    • Edited by M. Cooke and A. J. Dennis. Battelle Press, Columbus, OH
    • Katz M., Heddle J. A. and Salamone M. F. (1981) Mutagenic activity of polycyclic aromatic hydrocarbons and other environmental pollutants. In Polynuclear Aromatic Hydrocarbons-Polynuclear Aromatic Hydrocarbons. Edited by M. Cooke and A. J. Dennis, pp. 519. Battelle Press, Columbus, OH.
    • (1981) Polynuclear Aromatic Hydrocarbons-Polynuclear Aromatic Hydrocarbons , pp. 519
    • Katz, M.1    Heddle, J.A.2    Salamone, M.F.3
  • 72
    • 0000616162 scopus 로고
    • Conjugation by peptide bond formation
    • Edited by W. Jakoby. Academic Press, New York
    • Killenberg P. G. and Webster L. T. Jr (1980) Conjugation by peptide bond formation. In Enzymatic Basis of Detoxification. Edited by W. Jakoby. Vol. II, pp. 141-164. Academic Press, New York.
    • (1980) Enzymatic Basis of Detoxification , vol.2 , pp. 141-164
    • Killenberg, P.G.1    Webster L.T., Jr.2
  • 74
    • 3543142078 scopus 로고
    • Sur un substrat metabolique a action centrale inhibitrice. Le 4-hydroxybutyrate de Na
    • Laborit H., Jouany J. M., Gerard J. and Fabiani F. (1960) Sur un substrat metabolique a action centrale inhibitrice. Le 4-hydroxybutyrate de Na. Pressé Medicale 50, 1867-1869.
    • (1960) Pressé Medicale , vol.50 , pp. 1867-1869
    • Laborit, H.1    Jouany, J.M.2    Gerard, J.3    Fabiani, F.4
  • 75
    • 0028169868 scopus 로고
    • Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat
    • Lake B. G., Evans J. G., Lewis D. F. V. and Price R. J. (1994) Comparison of the hepatic effects of coumarin, 3,4-dimethylcoumarin, dihydrocoumarin and 6-methylcoumarin in the rat. Food and Chemical Toxicology 32, 743-751.
    • (1994) Food and Chemical Toxicology , vol.32 , pp. 743-751
    • Lake, B.G.1    Evans, J.G.2    Lewis, D.F.V.3    Price, R.J.4
  • 76
    • 0024584038 scopus 로고
    • Studies on the mechanism of coumarin-induced toxicity in rat hepatocytes: Comparison with dihydrocoumarin and other coumarin metabolites
    • Lake B. G., Gray T. J. B., Evans J. G., Lewis D. F. V., Beamand J. A. and Hue K. L. (1989) Studies on the mechanism of coumarin-induced toxicity in rat hepatocytes: Comparison with dihydrocoumarin and other coumarin metabolites. Toxicology and Applied Pharmacology 97, 311-323.
    • (1989) Toxicology and Applied Pharmacology , vol.97 , pp. 311-323
    • Lake, B.G.1    Gray, T.J.B.2    Evans, J.G.3    Lewis, D.F.V.4    Beamand, J.A.5    Hue, K.L.6
  • 77
    • 0002754959 scopus 로고
    • Structure-activity relationships for chemically produced peroxisome proliferation in mammalian liver
    • Edited by G. Gibson and B. Lake. Taylor & Francis, London
    • Lake B. G. and Lewis D. F. V. (1993) Structure-activity relationships for chemically produced peroxisome proliferation in mammalian liver. In Peroxisomes. Biology and Importance in Toxicology and Medicine. Edited by G. Gibson and B. Lake. pp. 313. Taylor & Francis, London.
    • (1993) Peroxisomes. Biology and Importance in Toxicology and Medicine , pp. 313
    • Lake, B.G.1    Lewis, D.F.V.2
  • 78
    • 0010462396 scopus 로고
    • The flavouring of confectionery
    • Edited by P. R. Ashurst. AVI, New York
    • Lawrence D. V. (1991) The flavouring of confectionery. In Food Flavourings. Edited by P. R. Ashurst. AVI, New York.
    • (1991) Food Flavourings
    • Lawrence, D.V.1
  • 79
    • 0017640526 scopus 로고
    • Evidence for the β-oxidation of orally administered γ-butyrolactone in humans
    • Lee C. R. (1977) Evidence for the β-oxidation of orally administered γ-butyrolactone in humans. Biochemistry and Medicine 17, 284-291.
    • (1977) Biochemistry and Medicine , vol.17 , pp. 284-291
    • Lee, C.R.1
  • 80
    • 0018176540 scopus 로고
    • Improved pharmacological activity via pro-drug modification: Comparative pharmacokinetics of sodium g-hydroxybutyrate and butyrolactone
    • Lettieri J. T. and Fung H. L. (1978) Improved pharmacological activity via pro-drug modification: comparative pharmacokinetics of sodium g-hydroxybutyrate and butyrolactone. Research Communications in Chemical Pathology and Pharmacology 22, 107-118.
    • (1978) Research Communications in Chemical Pathology and Pharmacology , vol.22 , pp. 107-118
    • Lettieri, J.T.1    Fung, H.L.2
  • 81
    • 0010500313 scopus 로고
    • Unpublished report to RIFM
    • Levenstein I. (1953). Unpublished report to RIFM.
    • (1953)
    • Levenstein, I.1
  • 82
    • 0010500173 scopus 로고
    • Unpublished report to RIFM
    • Levenstein I. (1974). Unpublished report to RIFM.
    • (1974)
    • Levenstein, I.1
  • 83
    • 0010420454 scopus 로고
    • Unpublished report to RIFM
    • Levenstein I. (1975). Unpublished report to RIFM.
    • (1975)
    • Levenstein, I.1
  • 84
    • 0010500174 scopus 로고
    • Unpublished report to RIFM
    • Lewis C. A. and Palanker A. L. (1979). Unpublished report to RIFM.
    • (1979)
    • Lewis, C.A.1    Palanker, A.L.2
  • 85
    • 0027992619 scopus 로고
    • Inhibition of rat hepatic aryl hydrocarbon hydrolase activity by a series of 7-hydroxycoumarins: QSAR studies
    • Lewis D. F. V., Lake B. L., Ioannides C. and Parke D. V. (1994) Inhibition of rat hepatic aryl hydrocarbon hydrolase activity by a series of 7-hydroxycoumarins: QSAR studies. Xenobiotica 24, 829-838.
    • (1994) Xenobiotica , vol.24 , pp. 829-838
    • Lewis, D.F.V.1    Lake, B.L.2    Ioannides, C.3    Parke, D.V.4
  • 87
    • 0019379114 scopus 로고
    • Studies on the mutagenic constituents of apple brandy and various alcoholic beverages collected in western France, a high incidence area for oesophageal cancer
    • Loquet C., Toussaint G. and LeTalear J. Y. (1981) Studies on the mutagenic constituents of apple brandy and various alcoholic beverages collected in western France, a high incidence area for oesophageal cancer. Mutation Research 88, 155-164.
    • (1981) Mutation Research , vol.88 , pp. 155-164
    • Loquet, C.1    Toussaint, G.2    LeTalear, J.Y.3
  • 88
    • 0000592451 scopus 로고
    • Salmonella/microsome tests on 42 coded chemicals
    • MacDonald D. J. (1981) Salmonella/microsome tests on 42 coded chemicals. Progress in Mutation Research 1, 285-297.
    • (1981) Progress in Mutation Research , vol.1 , pp. 285-297
    • MacDonald, D.J.1
  • 89
    • 0027247503 scopus 로고
    • Studies on the metabolism of a monoterpene ketone, R-(+)-pulegone - A hepatotoxin in rat: Isolation and characterization of new metabolites
    • Madyastha K. M. and Raj C. P. (1993) Studies on the metabolism of a monoterpene ketone, R-(+)-pulegone - a hepatotoxin in rat: isolation and characterization of new metabolites. Xenobiotica 23, 509-518.
    • (1993) Xenobiotica , vol.23 , pp. 509-518
    • Madyastha, K.M.1    Raj, C.P.2
  • 90
    • 0022842842 scopus 로고
    • Treatment of narcolepsy with gamma-hydroxybutyrate: A review of clinical and sleep laboratory findings
    • Mamelak M., Scharf M. B. and Woods M. (1986) Treatment of narcolepsy with gamma-hydroxybutyrate: A review of clinical and sleep laboratory findings. Sleep 9, 285-289; cited in Ferrara SD, Zotti S, Tedeschi L, Frison G, Castagna F, Gallimberti L, Gessa GL, Palantini P. (1992) Pharmacokinetics of γ-hydroxybutyric acid in alcohol dependent patients after single and repeated oral doses. British Journal of Clinical Pharmacology 34, 231-235.
    • (1986) Sleep , vol.9 , pp. 285-289
    • Mamelak, M.1    Scharf, M.B.2    Woods, M.3
  • 91
    • 0026794477 scopus 로고
    • Pharmacokinetics of γ-hydroxybutyric acid in alcohol dependent patients after single and repeated oral doses
    • Mamelak M., Scharf M. B. and Woods M. (1986) Treatment of narcolepsy with gamma-hydroxybutyrate: A review of clinical and sleep laboratory findings. Sleep 9, 285-289; cited in Ferrara SD, Zotti S, Tedeschi L, Frison G, Castagna F, Gallimberti L, Gessa GL, Palantini P. (1992) Pharmacokinetics of γ-hydroxybutyric acid in alcohol dependent patients after single and repeated oral doses. British Journal of Clinical Pharmacology 34, 231-235.
    • (1992) British Journal of Clinical Pharmacology , vol.34 , pp. 231-235
    • Ferrara, S.D.1    Zotti, S.2    Tedeschi, L.3    Frison, G.4    Castagna, F.5    Gallimberti, L.6    Gessa, G.L.7    Palantini, P.8
  • 92
    • 85047694480 scopus 로고
    • Interpretation of rodent hepatocellular proliferative alterations and hepatocellular tumors in chemical safety assessment
    • Maronpot R. R. and Boorman G. A. (1982) Interpretation of rodent hepatocellular proliferative alterations and hepatocellular tumors in chemical safety assessment. Toxicologic Pathology 10, 71-80.
    • (1982) Toxicologic Pathology , vol.10 , pp. 71-80
    • Maronpot, R.R.1    Boorman, G.A.2
  • 94
    • 0000304628 scopus 로고
    • Testing of 42 coded compounds for their ability to induce unscheduled DNA repair synthesis in HeLa cells
    • Martin C. N. and McDermid A. C. (1981) Testing of 42 coded compounds for their ability to induce unscheduled DNA repair synthesis in HeLa Cells. Progress in Mutation Research 1, 533-537.
    • (1981) Progress in Mutation Research , vol.1 , pp. 533-537
    • Martin, C.N.1    McDermid, A.C.2
  • 95
    • 0025214234 scopus 로고
    • Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity
    • Miles J. S., McClaren A. W., Forrester L. M., Glancey M. J., Lang M. A. and Wolf C. R. (1990) Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity. Biochemical Journal 267, 365-371.
    • (1990) Biochemical Journal , vol.267 , pp. 365-371
    • Miles, J.S.1    McClaren, A.W.2    Forrester, L.M.3    Glancey, M.J.4    Lang, M.A.5    Wolf, C.R.6
  • 96
    • 0017112561 scopus 로고
    • Gamma-hydroxybutyrate degradation in the brain in vivo: Negligible direct conversion to GABA
    • Möhler H., Patel A. J. and Balázs R. (1976) Gamma-hydroxybutyrate degradation in the brain in vivo: Negligible direct conversion to GABA. Journal of Neurochemistry 27, 253-258.
    • (1976) Journal of Neurochemistry , vol.27 , pp. 253-258
    • Möhler, H.1    Patel, A.J.2    Balázs, R.3
  • 98
    • 0010500175 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1972). Unpublished report to RIFM.
    • (1972)
    • Moreno, O.M.1
  • 99
    • 0010461947 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1973). Unpublished report to RIFM.
    • (1973)
    • Moreno, O.M.1
  • 100
    • 0010461007 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1974). Unpublished report to RIFM.
    • (1974)
    • Moreno, O.M.1
  • 101
    • 0010420879 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1975a). Unpublished report to RIFM.
    • (1975)
    • Moreno, O.M.1
  • 102
    • 0010463346 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1975b). Unpublished report to RIFM.
    • (1975)
    • Moreno, O.M.1
  • 103
    • 0010500176 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1976). Unpublished report to RIFM.
    • (1976)
    • Moreno, O.M.1
  • 104
    • 0010420308 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1977). Unpublished report to RIFM.
    • (1977)
    • Moreno, O.M.1
  • 105
    • 0010419880 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1978). Unpublished report to RIFM.
    • (1978)
    • Moreno, O.M.1
  • 106
    • 0010420016 scopus 로고
    • Unpublished report to RIFM
    • Moreno O. M. (1980). Unpublished report to RIFM.
    • (1980)
    • Moreno, O.M.1
  • 109
    • 0010461116 scopus 로고
    • Chirality evaluation in flavour analysis
    • Edited by A. Bessiere and A. F. Thomas. John Wiley & Sons, New York, NY
    • Mosandl A., Hagenauer-Hener U., Lehmann D., Kreis P. and Schmarr H-G. (1990) Chirality evaluation in flavour analysis. In Flavour Science and Technology. Edited by A. Bessiere and A. F. Thomas, pp. 21. John Wiley & Sons, New York, NY.
    • (1990) Flavour Science and Technology , pp. 21
    • Mosandl, A.1    Hagenauer-Hener, U.2    Lehmann, D.3    Kreis, P.4    Schmarr, H.-G.5
  • 110
    • 84920316863 scopus 로고
    • Biological evaluation of a flavour cocktail. 2. 13-week study in rats
    • Munday R. and Kirkby W. W. (1971) Biological evaluation of a flavour cocktail. 2. 13-Week study in rats. Research Report PCW 71 1624.
    • (1971) Research Report PCW , vol.71 , pp. 1624
    • Munday, R.1    Kirkby, W.W.2
  • 111
    • 84920307075 scopus 로고
    • Biological evaluation of a flavour cocktail. 3. One-year feeding study in rats
    • Munday R. and Kirkby W. W. (1973) Biological evaluation of a flavour cocktail. 3. One-year feeding study in rats. Research Report PCW 73 1103.
    • (1973) Research Report PCW , vol.73 , pp. 1103
    • Munday, R.1    Kirkby, W.W.2
  • 112
    • 0000288759 scopus 로고
    • Mutagenic activity of 42 coded compounds in the salmonella/microsome assay
    • Nagao M. and Takahashi Y. (1981) Mutagenic activity of 42 coded compounds in the salmonella/microsome assay. Progress in Mutation Research 1, 302-313.
    • (1981) Progress in Mutation Research , vol.1 , pp. 302-313
    • Nagao, M.1    Takahashi, Y.2
  • 118
    • 0003541547 scopus 로고
    • NTP-TR-394; NIH Publication No. 93-2849. Research Triangle Park, NC
    • 1 mice (gavage studies). NTP-TR-394; NIH Publication No. 93-2849. Research Triangle Park, NC.
    • (1993) 1 Mice (Gavage Studies)
  • 119
    • 0028171299 scopus 로고
    • Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose
    • Nutley P. B., Farmer P. and Caldwell J. (1994) Metabolism of trans-cinnamic acid in the rat and the mouse and its variation with dose. Food and Chemical Toxicology 32, 877-886.
    • (1994) Food and Chemical Toxicology , vol.32 , pp. 877-886
    • Nutley, P.B.1    Farmer, P.2    Caldwell, J.3
  • 121
    • 0010461539 scopus 로고
    • Unpublished report to RIFM
    • Oser B. L. (1962). Unpublished report to RIFM.
    • (1962)
    • Oser, B.L.1
  • 122
    • 0010501029 scopus 로고
    • Unpublished report to RIFM
    • Oser B. L. (1963). Unpublished report to RIFM.
    • (1963)
    • Oser, B.L.1
  • 124
    • 0010459983 scopus 로고
    • Unpublished report to RIFM
    • Paynter H. (1957). Unpublished report to RIFM.
    • (1957)
    • Paynter, H.1
  • 125
    • 0026781890 scopus 로고
    • Species differences and interindividual variation in the level of cytochrome P-450 2A enzymes: Effects of coumarin, dicumarol and testosterone oxidation
    • Pearce R., Greenway D. and Parkinson A. (1992) Species differences and interindividual variation in the level of cytochrome P-450 2A enzymes: effects of coumarin, dicumarol and testosterone oxidation. Archives of Biochemistry and Biophysics 298, 211-225.
    • (1992) Archives of Biochemistry and Biophysics , vol.298 , pp. 211-225
    • Pearce, R.1    Greenway, D.2    Parkinson, A.3
  • 126
    • 0010420456 scopus 로고
    • Unpublished report to RIFM
    • Pellmont I. (1970). Unpublished report to RIFM.
    • (1970)
    • Pellmont, I.1
  • 130
    • 0010420880 scopus 로고
    • Unpublished report to RIFM
    • Posternak J. M. (1965). Unpublished report to RIFM.
    • (1965)
    • Posternak, J.M.1
  • 132
    • 0016223141 scopus 로고
    • Phenylpropionic acid in the urine of patients with phenylketonuria and normals
    • Pollitt R. J. (1974) Phenylpropionic acid in the urine of patients with phenylketonuria and normals. Clinica Chimica Acta 55, 317-322.
    • (1974) Clinica Chimica Acta , vol.55 , pp. 317-322
    • Pollitt, R.J.1
  • 133
    • 0020322606 scopus 로고
    • Evaluation, using Salmonella typhimurium, of the mutagenicity of seven chemicals found in cosmetics
    • Prival M. J., Sheldon A. T., Jr and Popkin D. (1982) Evaluation, using Salmonella typhimurium, of the mutagenicity of seven chemicals found in cosmetics. Food and Chemical Toxicology 20, 427-432.
    • (1982) Food and Chemical Toxicology , vol.20 , pp. 427-432
    • Prival, M.J.1    Sheldon A.T., Jr.2    Popkin, D.3
  • 134
    • 0026934672 scopus 로고
    • Interindividual variability of coumarin 7-hydroxylation in healthy volunteers
    • Rautio A., Kraul H., Kojo A., Salmela E. and Pelkonen O. (1992) Interindividual variability of coumarin 7-hydroxylation in healthy volunteers. Pharmacogenetics 2, 227-233.
    • (1992) Pharmacogenetics , vol.2 , pp. 227-233
    • Rautio, A.1    Kraul, H.2    Kojo, A.3    Salmela, E.4    Pelkonen, O.5
  • 136
    • 0000288761 scopus 로고
    • Mutagenic activity of 42 coded compounds in the salmonella/microsome assay
    • Richold M. and Jones E. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. Progress in Mutation Research 1, 314-322.
    • (1981) Progress in Mutation Research , vol.1 , pp. 314-322
    • Richold, M.1    Jones, E.2
  • 138
    • 84973743783 scopus 로고
    • Enzootic and epizootic adrenal medullary proliferative disease of rats: Influence of dietary factors which affect calcium absorption
    • Roe F. J. C. and Baer A. (1985) Enzootic and epizootic adrenal medullary proliferative disease of rats: Influence of dietary factors which affect calcium absorption. Human Toxicology 4, 27-52.
    • (1985) Human Toxicology , vol.4 , pp. 27-52
    • Roe, F.J.C.1    Baer, A.2
  • 140
    • 0018903411 scopus 로고
    • Gamma-hydroxybutyrate: A role in the regulation of central dopaminergic neurons?
    • Roth R. H., Doherty J. D. and Walters J. R. (1980) Gamma-hydroxybutyrate: A role in the regulation of central dopaminergic neurons? Brain Research 189, 556-560.
    • (1980) Brain Research , vol.189 , pp. 556-560
    • Roth, R.H.1    Doherty, J.D.2    Walters, J.R.3
  • 141
    • 0000897717 scopus 로고
    • Preliminary report on the metabolism of γ-butyrolactone and γ-hydroxybutyric acid
    • Roth R. H. and Giarman N. J. (1965) Preliminary report on the metabolism of γ-butyrolactone and γ-hydroxybutyric acid. Biochemical Pharmacology 14, 177-178.
    • (1965) Biochemical Pharmacology , vol.14 , pp. 177-178
    • Roth, R.H.1    Giarman, N.J.2
  • 142
    • 0001585572 scopus 로고
    • γ-butyrolactone and γ-hydroxybutyric acid-I. Distribution and metabolism
    • Roth R. H. and Giarman N. J. (1966) γ-Butyrolactone and γ-hydroxybutyric acid-I. Distribution and metabolism. Biochemical Pharmacology 15, 1333-1348.
    • (1966) Biochemical Pharmacology , vol.15 , pp. 1333-1348
    • Roth, R.H.1    Giarman, N.J.2
  • 143
    • 0014448322 scopus 로고
    • Conversion in vivo of γ-aminobutyric to γ-hydroxybutyric acid in the rat
    • Roth R. H. and Giarman N. J. (1969) Conversion in vivo of γ-aminobutyric to γ-hydroxybutyric acid in the rat. Biochemical Pharmacology 18, 247-250.
    • (1969) Biochemical Pharmacology , vol.18 , pp. 247-250
    • Roth, R.H.1    Giarman, N.J.2
  • 144
    • 0010420017 scopus 로고
    • Unpublished report to RIFM
    • Roubier C. (1991). Unpublished report to RIFM.
    • (1991)
    • Roubier, C.1
  • 145
    • 0000592458 scopus 로고
    • Mutagenicity of carcinogens and noncarcinogens in the salmonella/microsome test
    • Rowland I. and Severn B. (1981) Mutagenicity of carcinogens and noncarcinogens in the Salmonella/microsome test. Progress in Mutation Research 1, 323-332.
    • (1981) Progress in Mutation Research , vol.1 , pp. 323-332
    • Rowland, I.1    Severn, B.2
  • 146
    • 0022878425 scopus 로고
    • Metabolism of the cinnamon substituent o-methoxycinnamaldehyde in the rat
    • Samuelson O. B., Brenna J., Solheim E. and Scheline R. R. (1986) Metabolism of the cinnamon substituent o-methoxycinnamaldehyde in the rat. Xenobiotica 16, 845-852.
    • (1986) Xenobiotica , vol.16 , pp. 845-852
    • Samuelson, O.B.1    Brenna, J.2    Solheim, E.3    Scheline, R.R.4
  • 148
    • 0014378229 scopus 로고
    • Studies on the role of the intestinal micronora in the metabolism of coumarin in rats
    • Scheline R. R. (1968) Studies on the role of the intestinal micronora in the metabolism of coumarin in rats. Acta Pharmacologica et Toxicologica 26, 325-331.
    • (1968) Acta Pharmacologica et Toxicologica , vol.26 , pp. 325-331
    • Scheline, R.R.1
  • 149
    • 0007700685 scopus 로고
    • Induction of mitotic gene conversion by 41 compounds using the yeast culture JD1
    • Sharp D. C. and Parry J. M. (1981) Induction of mitotic gene conversion by 41 compounds using the yeast culture JD1. Progress in Mutation Research 1, 491-501.
    • (1981) Progress in Mutation Research , vol.1 , pp. 491-501
    • Sharp, D.C.1    Parry, J.M.2
  • 150
    • 0010501190 scopus 로고
    • Gulf South Research Institute. Unpublished report to RIFM
    • Shellenberger R. (1971) Gulf South Research Institute. Unpublished report to RIFM.
    • (1971)
    • Shellenberger, R.1
  • 151
    • 0010419882 scopus 로고
    • Gulf South Research Institute. Unpublished report to RIFM
    • Shellenberger R. (1973) Gulf South Research Institute. Unpublished report to RIFM.
    • (1973)
    • Shellenberger, R.1
  • 153
    • 0000288760 scopus 로고
    • Mutagenic activity 42 coded compounds in the salmonella/microsome assay
    • Simmon V. F. and Shepard G. F. (1981) Mutagenic activity 42 coded compounds in the Salmonella/microsome assay. Progress in Mutation Research 1, 333-342.
    • (1981) Progress in Mutation Research , vol.1 , pp. 333-342
    • Simmon, V.F.1    Shepard, G.F.2
  • 155
    • 0024784645 scopus 로고
    • In vivo conversion of (-aminobutyric acid and 1,4-butanediol to γ-hydroxybutyric acid in rat brain
    • Snead O. C., III Furner R. and Liu C. C. (1989) In vivo conversion of (-aminobutyric acid and 1,4-butanediol to γ-hydroxybutyric acid in rat brain. Biochemical Pharmacology 38, 4375-4380.
    • (1989) Biochemical Pharmacology , vol.38 , pp. 4375-4380
    • Snead O.C. III1    Furner, R.2    Liu, C.C.3
  • 156
    • 0007616016 scopus 로고
    • Activity of 42 coded compounds in the BHK-21 cell transformation tests
    • Styles J. A. (1981) Activity of 42 coded compounds in the BHK-21 Cell transformation tests. Progress in Mutation Research 1, 638-646.
    • (1981) Progress in Mutation Research , vol.1 , pp. 638-646
    • Styles, J.A.1
  • 157
    • 0002460382 scopus 로고
    • Consumption ratio and food predominance of flavouring materials
    • Stofberg J. and Grundschober F. (1987) Consumption ratio and food predominance of flavouring materials. Perfumer and Flavourist 12, 27.
    • (1987) Perfumer and Flavourist , vol.12 , pp. 27
    • Stofberg, J.1    Grundschober, F.2
  • 158
    • 0022410028 scopus 로고
    • The consumption ratio of flavouring materials: A mechanism for setting priorities for safety evaluation
    • Stofberg J. and Kirschman J. C. (1985) The consumption ratio of flavouring materials: A mechanism for setting priorities for safety evaluation. Food and Chemical Toxicology 23, 857-860.
    • (1985) Food and Chemical Toxicology , vol.23 , pp. 857-860
    • Stofberg, J.1    Kirschman, J.C.2
  • 160
    • 3142642203 scopus 로고
    • Biochemical mechanisms of renal toxicity
    • Edited by E. Hodgson and P. Levi. 2nd Ed. Appleton and Lange, Norwalk, CN
    • Tarloff J. B. and Goldstein R. S. (1994) Biochemical mechanisms of renal toxicity. In Biochemical Toxicology. Edited by E. Hodgson and P. Levi. 2nd Ed. Appleton and Lange, Norwalk, CN.
    • (1994) Biochemical Toxicology
    • Tarloff, J.B.1    Goldstein, R.S.2
  • 162
    • 0000542924 scopus 로고
    • Evaluation of some chemicals by the sperm morphology assay
    • Topham J. C. (1981) Evaluation of some chemicals by the sperm morphology assay. Progress in Mutation Research 1, 718-720.
    • (1981) Progress in Mutation Research , vol.1 , pp. 718-720
    • Topham, J.C.1
  • 164
    • 0000239858 scopus 로고
    • Activity of 42 coded compounds in the Salmonella reverse mutation test
    • Trueman R. W. (1981) Activity of 42 coded compounds in the Salmonella reverse mutation test. Progress in Mutation Research 1, 343-350.
    • (1981) Progress in Mutation Research , vol.1 , pp. 343-350
    • Trueman, R.W.1
  • 166
    • 0000689458 scopus 로고
    • Mutagenicity of 42 coded compounds in a bacterial assay using Escherichia coli and Salmonella typhimurium
    • Venitt S. and Crofton-Sleigh C. (1981) Mutagenicity of 42 coded compounds in a bacterial assay using Escherichia coli and Salmonella typhimurium. Progress in Mutation Research 1, 351-360.
    • (1981) Progress in Mutation Research , vol.1 , pp. 351-360
    • Venitt, S.1    Crofton-Sleigh, C.2
  • 172
    • 0039334728 scopus 로고
    • Dairy flavourings
    • Edited by P. R. Ashurst. AVI, New York
    • White S. and White G. (1991) Dairy flavourings. In Food Flavourings. Edited by P. R. Ashurst. AVI, New York.
    • (1991) Food Flavourings
    • White, S.1    White, G.2
  • 176
    • 0010500570 scopus 로고
    • Unpublished report to RIFM
    • Wohl A. (1974). Unpublished report to RIFM.
    • (1974)
    • Wohl, A.1
  • 177
    • 0025022689 scopus 로고
    • The CYP2A3 gene product catalyses coumarin 7-hydroxylation in human liver microsomes
    • Yamano S., Tatsuno J. and Gonzalez F. J. (1990) The CYP2A3 gene product catalyses coumarin 7-hydroxylation in human liver microsomes. Biochemistry 29, 1322-1329.
    • (1990) Biochemistry , vol.29 , pp. 1322-1329
    • Yamano, S.1    Tatsuno, J.2    Gonzalez, F.J.3
  • 178
    • 0026744568 scopus 로고
    • Cytochrome P-4502E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
    • Yamazaki H., Inui I., Yun C. H., Guengerich F. P. and Shimada T. (1992) Cytochrome P-4502E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis 13, 1789-1794.
    • (1992) Carcinogenesis , vol.13 , pp. 1789-1794
    • Yamazaki, H.1    Inui, I.2    Yun, C.H.3    Guengerich, F.P.4    Shimada, T.5
  • 180
    • 0010420023 scopus 로고
    • Mutagenic and antimutagenic activities of flavouring agents used in foodstuffs
    • Yoo Y. S. (1986) Mutagenic and antimutagenic activities of flavouring agents used in foodstuffs. Journal of the Osaka City Medical Center 34, 267-288.
    • (1986) Journal of the Osaka City Medical Center , vol.34 , pp. 267-288
    • Yoo, Y.S.1
  • 181
    • 0015093147 scopus 로고
    • Profile of volatile metabolites in human urine
    • Zlatkis A. and Liebich H. M. (1971) Profile of volatile metabolites in human urine. Clinical Chemistry 17, 592-594.
    • (1971) Clinical Chemistry , vol.17 , pp. 592-594
    • Zlatkis, A.1    Liebich, H.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.