Differential modulation of late sodium current by protein kinase A in R1623Q mutant of LQT3

Life Sciences

Volumn 84, Issue 11-12, 2009, Pages 380-387

  Tsurugi, Takuo ^a   Nagatomo, Toshihisa ^a   Abe, Haruhiko ^a   Oginosawa, Yasushi ^a   Takemasa, Hiroko ^a   Kohno, Ritsuko ^a   Makita, Naomasa ^b   Makielski, Jonathan C ^c   Otsuji, Yutaka ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Arrhythmia; Long QT syndrome; Protein kinase A; Sodium channel

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FLUORIDE; MUTANT PROTEIN; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BETA ADRENERGIC STIMULATION; CELL LINE; CHANNEL GATING; GENE MUTATION; GENETIC TRANSFECTION; HEART PACING; HEART RATE; HUMAN; HUMAN CELL; LONG QT SYNDROME; LONG QT SYNDROME TYPE 3; PATCH CLAMP; PROTEIN FUNCTION; QT INTERVAL; SODIUM CURRENT;

ACTION POTENTIALS; CELL LINE; CLONING, MOLECULAR; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FLUORIDES; HUMANS; ION CHANNEL GATING; LONG QT SYNDROME; MUSCLE PROTEINS; MUTATION; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE INHIBITORS; SODIUM CHANNELS; THIONUCLEOTIDES; TRANSFECTION;

EID: 60149112633     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2009.01.001     Document Type: Article

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