Differential response to Na+ channel blockade, β-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long-QT syndrome

Circulation Research

Volumn 78, Issue 6, 1996, Pages 1009-1015

  Priori, Silvia G ^a   Napolitano, Carlo ^a   Cantù, Francesco ^a   Brown, Arthur M ^b   Schwartz, Peter J ^a,c  

^a UNIVERSITY OF MILAN   (Italy)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

genetic defects; long QT syndrome; Na+ channel blockade; sudden death; sympathetic stimulation

Indexed keywords

ANTHOPLEURIN A; DOFETILIDE; ISOPRENALINE; MEXILETINE; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; BETA ADRENERGIC STIMULATION; CHANNEL GATING; CHROMOSOME 3; CHROMOSOME 7; CONTROLLED STUDY; DRUG EFFECT; GENE MUTATION; GUINEA PIG; HEART MUSCLE POTENTIAL; HEART PACING; HEART REPOLARIZATION; HEART VENTRICLE WALL; LONG QT SYNDROME; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; SUDDEN DEATH;

EID: 0029887380     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.78.6.1009     Document Type: Article

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