Evaluation of the effects of vitamin A supplementation on adult rat substantia nigra and striatum redox and bioenergetic states: Mitochondrial impairment, increased 3-nitrotyrosine and α-synuclein, but decreased D2 receptor contents

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 33, Issue 2, 2009, Pages 353-362

  de Oliveira, Marcos Roberto ^a   Oliveira, Max William Soares ^a   Behr, Guilherme Antônio ^a   Hoff, Mariana Leivas Muller ^a   da Rocha, Ricardo Fagundes ^a   Moreira, José Cláudio Fonseca ^a  

^a Instituto de Ciencias Biologicas e da Saude Pontifical Catholic University of Minas Gerais   (Brazil)

Author keywords

synuclein; Mitochondrial electron transfer chain; Striatum; Substantia nigra; Superoxide anion; Vitamin A

Indexed keywords

3 NITROTYROSINE; ALPHA SYNUCLEIN; ANTIOXIDANT; DOPAMINE 2 RECEPTOR; RETINOL PALMITATE; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA;

ADULT ANIMAL; ANIMAL EXPERIMENT; ARTICLE; BIOENERGY; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; DRUG MECHANISM; ELECTRON TRANSPORT; ENZYME LINKED IMMUNOSORBENT ASSAY; MALE; MITOCHONDRION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RAT; SUBSTANTIA NIGRA; VITAMIN SUPPLEMENTATION;

ALPHA-SYNUCLEIN; ANIMALS; CASPASE 3; DIETARY SUPPLEMENTS; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX III; ELECTRON TRANSPORT COMPLEX IV; ENERGY METABOLISM; FREE RADICAL SCAVENGERS; GLUTATHIONE TRANSFERASE; INDICATORS AND REAGENTS; MITOCHONDRIA; NEOSTRIATUM; OXIDATION-REDUCTION; RATS; RECEPTORS, DOPAMINE D2; SUBSTANTIA NIGRA; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE; VITAMIN A; VITAMINS;

EID: 60149110679     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pnpbp.2008.12.020     Document Type: Article

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