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Volumn 9, Issue , 2009, Pages

Combined xanthorrhizol-curcumin exhibits synergistic growth inhibitory activity via apoptosis induction in human breast cancer cells MDA-MB-231

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTINEOPLASTIC AGENT; CURCUMIN; CURCUMIN PLUS XANTHORRHIZOL; DNA; NATURAL PRODUCT; SULFORHODAMINE B; UNCLASSIFIED DRUG; XANTHORRHIZOL;

EID: 60149089513     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/1475-2867-9-1     Document Type: Article
Times cited : (62)

References (62)
  • 1
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • 10.1021/np068054v 17309302
    • Newman DJ Cragg GM Natural products as sources of new drugs over the last 25 years J Nat Prod 2007, 70:461-477 10.1021/np068054v 17309302
    • (2007) J Nat Prod , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 2
    • 21344447259 scopus 로고    scopus 로고
    • Xanthorrhizol induces apoptosis via the up-regulation of bax and p53 in HeLa cells
    • 16158967
    • Ismail N Pihie AH Nallapan M Xanthorrhizol induces apoptosis via the up-regulation of bax and p53 in HeLa cells Anticancer Res 2005, 25:2221-2227 16158967
    • (2005) Anticancer Res , vol.25 , pp. 2221-2227
    • Ismail, N.1    Pihie, A.H.2    Nallapan, M.3
  • 3
    • 33845935202 scopus 로고    scopus 로고
    • Xanthorrhizol exhibits antiproliferative activity on MCF-7 breast cancer cells via apoptosis induction
    • 17201174
    • Cheah YH Azimahtol HL Abdullah NR Xanthorrhizol exhibits antiproliferative activity on MCF-7 breast cancer cells via apoptosis induction Anticancer Res 2006, 26:4527-4534 17201174
    • (2006) Anticancer Res , vol.26 , pp. 4527-4534
    • Cheah, Y.H.1    Azimahtol, H.L.2    Abdullah, N.R.3
  • 4
    • 34247155896 scopus 로고    scopus 로고
    • Regulation of p53-, Bcl-2-, and caspase-dependent signaling pathway in xanthorrhizol-induced apoptosis of HepG2 hepatoma cells
    • 17465228
    • Handayani T Sakinah S Nallapan M Pihie AH Regulation of p53-, Bcl-2-, and caspase-dependent signaling pathway in xanthorrhizol-induced apoptosis of HepG2 hepatoma cells Anticancer Res 2007, 27:965-971 17465228
    • (2007) Anticancer Res , vol.27 , pp. 965-971
    • Handayani, T.1    Sakinah, S.2    Nallapan, M.3    Pihie, A.H.4
  • 5
    • 38749109673 scopus 로고    scopus 로고
    • Curcumin as "curecumin": From kitchen to clinic
    • 10.1016/j.bcp.2007.08.016 17900536
    • Goel A Kunnumakkara AB Aggarwal BB Curcumin as "curecumin": from kitchen to clinic Biochem Pharmacol 2008, 75:787-809 10.1016/ j.bcp.2007.08.016 17900536
    • (2008) Biochem Pharmacol , vol.75 , pp. 787-809
    • Goel, A.1    Kunnumakkara, A.B.2    Aggarwal, B.B.3
  • 6
    • 45849143337 scopus 로고    scopus 로고
    • Cytotoxic effects of curcumin on osteosarcoma cell lines
    • 10.1007/s10637-007-9099-7 18071634
    • Walters DK Muff R Langsam B Born W Fuchs B Cytotoxic effects of curcumin on osteosarcoma cell lines Invest New Drugs 2008, 26:289-297 10.1007/ s10637-007-9099-7 18071634
    • (2008) Invest New Drugs , vol.26 , pp. 289-297
    • Walters, D.K.1    Muff, R.2    Langsam, B.3    Born, W.4    Fuchs, B.5
  • 7
    • 39149116345 scopus 로고    scopus 로고
    • Curcumin induces apoptosis through an ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells
    • 18187158
    • Liao YF Hung HC Hour TC Hsu PC Kao MC Tsay GJ Liu GY Curcumin induces apoptosis through an ornithine decarboxylase-dependent pathway in human promyelocytic leukemia HL-60 cells Life Sci 2008, 82:367-375 18187158
    • (2008) Life Sci , vol.82 , pp. 367-375
    • Liao, Y.F.1    Hung, H.C.2    Hour, T.C.3    Hsu, P.C.4    Kao, M.C.5    Tsay, G.J.6    Liu, G.Y.7
  • 8
    • 0037130290 scopus 로고    scopus 로고
    • Preferential targeting of apoptosis in tumor versus normal cells
    • 12084473
    • Woynarowska BA Woynarowski JM Preferential targeting of apoptosis in tumor versus normal cells Biochim Biophys Acta 2002, 1587:309-317 12084473
    • (2002) Biochim Biophys Acta , vol.1587 , pp. 309-317
    • Woynarowska, B.A.1    Woynarowski, J.M.2
  • 9
    • 44849099306 scopus 로고    scopus 로고
    • Membrane-thinning effect of curcumin
    • 10.1529/biophysj.107.126888 18310254
    • Hung WC Chen FY Lee CC Sun Y Lee MT Huang HW Membrane-thinning effect of curcumin Biophys J 2008, 94:4331-4338 10.1529/biophysj.107.126888 18310254
    • (2008) Biophys J , vol.94 , pp. 4331-4338
    • Hung, W.C.1    Chen, F.Y.2    Lee, C.C.3    Sun, Y.4    Lee, M.T.5    Huang, H.W.6
  • 10
    • 0023512993 scopus 로고
    • Influence of docosahexaenoic acid in vitro on intracellular adriamycin concentration in lymphocytes and human adriamycin-sensitive and -resistant small cell lung carcinoma cell line
    • 10.1002/ijc.2910400625 2826341
    • Zijlstra JG de Vries EGE Muskiet FAJ Martini LA Timmer-Bosscha H Mulder NH Influence of docosahexaenoic acid in vitro on intracellular adriamycin concentration in lymphocytes and human adriamycin-sensitive and -resistant small cell lung carcinoma cell line Int J Cancer 1987, 40:850-856 10.1002/ijc.2910400625 2826341
    • (1987) Int J Cancer , vol.40 , pp. 850-856
    • Zijlstra, J.G.1    de Vries, E.G.E.2    Muskiet, F.A.J.3    Martini, L.A.4    Timmer-Bosscha, H.5    Mulder, N.H.6
  • 12
    • 0030806425 scopus 로고    scopus 로고
    • Digitonin enhances the efficacy of carboplatin in liver tumour after intra-arterial administration
    • 10.1007/s002800050684 9272123
    • Lindner PG Heath D Howell SB Naredi PL Hafstrom LR Digitonin enhances the efficacy of carboplatin in liver tumour after intra-arterial administration Cancer Chemother Pharmacol 1997, 40:444-448 10.1007/ s002800050684 9272123
    • (1997) Cancer Chemother Pharmacol , vol.40 , pp. 444-448
    • Lindner, P.G.1    Heath, D.2    Howell, S.B.3    Naredi, P.L.4    Hafstrom, L.R.5
  • 14
    • 33750087577 scopus 로고    scopus 로고
    • Effect of coating the wells of polystyrene microtiter plate with xanthorrhizol on the biofilm formation of streptococcus mutans
    • 10.1002/jobm.200510088 17009296
    • Rukayadi Y Hwang JK Effect of coating the wells of polystyrene microtiter plate with xanthorrhizol on the biofilm formation of streptococcus mutans J Basic Microbiol 2006, 46:410-425 10.1002/ jobm.200510088 17009296
    • (2006) J Basic Microbiol , vol.46 , pp. 410-425
    • Rukayadi, Y.1    Hwang, J.K.2
  • 15
    • 0028116672 scopus 로고
    • Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron
    • 10.1007/BF00926033 7845373
    • Reddy AC Lokesh BR Studies on the inhibitory effects of curcumin and eugenol on the formation of reactive oxygen species and the oxidation of ferrous iron Mol Cell Biochem 1994, 137:1-8 10.1007/BF00926033 7845373
    • (1994) Mol Cell Biochem , vol.137 , pp. 1-8
    • Reddy, A.C.1    Lokesh, B.R.2
  • 16
    • 0032537814 scopus 로고    scopus 로고
    • Inhibition of the c-Jun N-terminal kinase (JNK) signalling pathway by curcumin
    • 10.1038/sj.onc.1201941 9674701
    • Chen YR Tan TH Inhibition of the c-Jun N-terminal kinase (JNK) signalling pathway by curcumin Oncogene 1998, 17:173-178 10.1038/ sj.onc.1201941 9674701
    • (1998) Oncogene , vol.17 , pp. 173-178
    • Chen, Y.R.1    Tan, T.H.2
  • 17
    • 0036645522 scopus 로고    scopus 로고
    • Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer
    • 12097302
    • Somasundaram S Edmund NA Moore DT Small GW Shi YY Orlowski RZ Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer Cancer Res 2002, 62:3868-3875 12097302
    • (2002) Cancer Res , vol.62 , pp. 3868-3875
    • Somasundaram, S.1    Edmund, N.A.2    Moore, D.T.3    Small, G.W.4    Shi, Y.Y.5    Orlowski, R.Z.6
  • 19
    • 29344455140 scopus 로고    scopus 로고
    • Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29
    • 10.1159/000090238 16340194
    • Du B Jiang L Xia Q Zhong L Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29 Chemotherapy 2006, 52:23-28 10.1159/000090238 16340194
    • (2006) Chemotherapy , vol.52 , pp. 23-28
    • Du, B.1    Jiang, L.2    Xia, Q.3    Zhong, L.4
  • 20
    • 18044363456 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun N-terminal kinases (JNKs) is involved in the preventive effects of xanthorrhizol on ciplatin-induced hepatotoxicity
    • 10.1007/s00204-004-0623-7 15536542
    • Hong KO Hwang JK Park KK Kim SH Phosphorylation of c-Jun N-terminal kinases (JNKs) is involved in the preventive effects of xanthorrhizol on ciplatin-induced hepatotoxicity Arch Toxicol 2005, 79:231-236 10.1007/ s00204-004-0623-7 15536542
    • (2005) Arch Toxicol , vol.79 , pp. 231-236
    • Hong, K.O.1    Hwang, J.K.2    Park, K.K.3    Kim, S.H.4
  • 21
    • 33244476761 scopus 로고    scopus 로고
    • Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells
    • 10.1016/j.cellbi.2005.10.024 16376585
    • Shi M Cai Q Yao L Mao Y Ming Y Ouyang G Antiproliferation and apoptosis induced by curcumin in human ovarian cancer cells Cell Biol Int 2006, 30:221-226 10.1016/j.cellbi.2005.10.024 16376585
    • (2006) Cell Biol Int , vol.30 , pp. 221-226
    • Shi, M.1    Cai, Q.2    Yao, L.3    Mao, Y.4    Ming, Y.5    Ouyang, G.6
  • 22
    • 0036195104 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl
    • 10.1093/carcin/23.1.143 11756235
    • Anto RJ Mukhopadhyay A Denning K Aggarwal Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl Carcinogenesis 2002, 23:143-150 10.1093/carcin/23.1.143 11756235
    • (2002) Carcinogenesis , vol.23 , pp. 143-150
    • Anto, R.J.1    Mukhopadhyay, A.2    Denning, K.3    Aggarwal4
  • 23
    • 0028674527 scopus 로고
    • Why are estrogen-receptor-negative breast cancer more aggressive than the estrogen-receptor-positive breast cancers?
    • (1Lj) 7657526
    • Sheikh MS Garcia M Pujol P Fontana JA Rochefort H Why are estrogen-receptor-negative breast cancer more aggressive than the estrogen-receptor-positive breast cancers? Invasion Metastasis 1995, 14(1Lj):329-336 7657526
    • (1995) Invasion Metastasis , vol.14 , pp. 329-336
    • Sheikh, M.S.1    Garcia, M.2    Pujol, P.3    Fontana, J.A.4    Rochefort, H.5
  • 24
    • 0030865104 scopus 로고    scopus 로고
    • Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth inhibitory potency of 123 anticancer agents
    • 9331090
    • O'Connor PM Jackman J Bae I Myers TG Fan S Mutoh M Scudiero DA Monks A Sausville EA Weinstein JN Friend S Jr AJF Kohn KW Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth inhibitory potency of 123 anticancer agents Cancer Res 1997, 57:4285-4300 9331090
    • (1997) Cancer Res , vol.57 , pp. 4285-4300
    • O'Connor, P.M.1    Jackman, J.2    Bae, I.3    Myers, T.G.4    Fan, S.5    Mutoh, M.6    Scudiero, D.A.7    Monks, A.8    Sausville, E.A.9    Weinstein, J.N.10    Friend Jr., S.A.J.F.11    Kohn, K.W.12
  • 25
    • 0038547793 scopus 로고    scopus 로고
    • Matrix metalloproteinase expression in breast cancer
    • 10.1016/S0022-4804(03)00007-6
    • Bartsch JE Staren ED Appert HE Matrix metalloproteinase expression in breast cancer J Surgl Res 2003, 110:383-392 10.1016/S0022-4804(03)00007-6
    • (2003) J Surgl Res , vol.110 , pp. 383-392
    • Bartsch, J.E.1    Staren, E.D.2    Appert, H.E.3
  • 27
    • 0344198117 scopus 로고    scopus 로고
    • TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer
    • 14654539
    • Geisler S Borresen-Dale Al Johnsen H Aas T Geisler J Akslen LA Anker G Lonning PE TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer Clin Cancer Res 2003, 9:5582-5588 14654539
    • (2003) Clin Cancer Res , vol.9 , pp. 5582-5588
    • Geisler, S.1    Borresen-Dale, A.L.2    Johnsen, H.3    Aas, T.4    Geisler, J.5    Akslen, L.A.6    Anker, G.7    Lonning, P.E.8
  • 28
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor genes: Clues to cancer etiology and molecular pathogenesis
    • 8069852
    • Greenblatt MS Bennett WP Hollstein M Harris CC Mutations in the p53 tumor suppressor genes: Clues to cancer etiology and molecular pathogenesis Cancer Res 1994, 54:4855-4878 8069852
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 29
    • 0035720521 scopus 로고    scopus 로고
    • Pharmacology of oral combination analgesics: Rational therapy for pain
    • 10.1046/j.1365-2710.2001.00355.x 11493367
    • Raffa RB Pharmacology of oral combination analgesics: Rational therapy for pain J Clin Pharm Ther 2001, 26:257-264 10.1046/ j.1365-2710.2001.00355.x 11493367
    • (2001) J Clin Pharm Ther , vol.26 , pp. 257-264
    • Raffa, R.B.1
  • 30
    • 9644268126 scopus 로고    scopus 로고
    • Xanthorrhizol, a natural sesquiterpenoid from Curcuma xanthorrhiza, has an anti-metastatic potential in experimental mouse lung metastatic model
    • 10.1016/j.bbrc.2004.11.020 15567173
    • Choi MA Kim Sh Chung WY Hwang JK Park KK Xanthorrhizol, a natural sesquiterpenoid from Curcuma xanthorrhiza, has an anti-metastatic potential in experimental mouse lung metastatic model Biochem Biophys Res Comm 2005, 326:210-217 10.1016/j.bbrc.2004.11.020 15567173
    • (2005) Biochem Biophys Res Comm , vol.326 , pp. 210-217
    • Choi, M.A.1    Kim, Sh.2    Chung, W.Y.3    Hwang, J.K.4    Park, K.K.5
  • 31
    • 51949108822 scopus 로고    scopus 로고
    • Antibacterial activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb. against foodborne pathogens
    • 18810881
    • Lee LY Shim JS Rukayadi Y Hwang JK Antibacterial activity of xanthorrhizol isolated from Curcuma xanthorrhiza Roxb. against foodborne pathogens J Food Prot 2008, 71:1926-1930 18810881
    • (2008) J Food Prot , vol.71 , pp. 1926-1930
    • Lee, L.Y.1    Shim, J.S.2    Rukayadi, Y.3    Hwang, J.K.4
  • 32
    • 33645064048 scopus 로고    scopus 로고
    • In vitro activity of xanthorrhizol against Streptococcus mutans biofilms
    • 10.1111/j.1472-765X.2006.01876.x 16599995
    • Rukayadi Y Hwang JK In vitro activity of xanthorrhizol against Streptococcus mutans biofilms Lett Appl Microbiol 2006, 42:400-404 10.1111/j.1472-765X.2006.01876.x 16599995
    • (2006) Lett Appl Microbiol , vol.42 , pp. 400-404
    • Rukayadi, Y.1    Hwang, J.K.2
  • 33
    • 1942471767 scopus 로고    scopus 로고
    • Abbrogation of cisplatin-induced hepatotoxicity in mice by xanthorrhizol is related to its effects on the regulation of gene transcription
    • 10.1016/j.taap.2003.11.020 15094305
    • Kim SH Hong KO Chung WY Hwang JK Park KK Abbrogation of cisplatin-induced hepatotoxicity in mice by xanthorrhizol is related to its effects on the regulation of gene transcription Toxicol Appl Pharmacol 2004, 196:346-355 10.1016/j.taap.2003.11.020 15094305
    • (2004) Toxicol Appl Pharmacol , vol.196 , pp. 346-355
    • Kim, S.H.1    Hong, K.O.2    Chung, W.Y.3    Hwang, J.K.4    Park, K.K.5
  • 34
    • 9744276713 scopus 로고    scopus 로고
    • Xanthorrhizol has a potential to attenuate the high dose cisplatin-induced nephrotoxicity in mice
    • 10.1016/j.fct.2004.08.018 15582203
    • Kim SH Hong KO Hwang JK Park KK Xanthorrhizol has a potential to attenuate the high dose cisplatin-induced nephrotoxicity in mice Food Chem Toxicol 2005, 43:117-122 10.1016/j.fct.2004.08.018 15582203
    • (2005) Food Chem Toxicol , vol.43 , pp. 117-122
    • Kim, S.H.1    Hong, K.O.2    Hwang, J.K.3    Park, K.K.4
  • 35
    • 28544452918 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia
    • 10.1002/jnr.20692 16273545
    • Lim CS Jin DQ Mok H Oh SJ Lee JU Hwang JK Ha I Han JS Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia J Neurosci Res 2005, 82:831-838 10.1002/ jnr.20692 16273545
    • (2005) J Neurosci Res , vol.82 , pp. 831-838
    • Lim, C.S.1    Jin, D.Q.2    Mok, H.3    Oh, S.J.4    Lee, J.U.5    Hwang, J.K.6    Ha, I.7    Han, J.S.8
  • 36
    • 0022382577 scopus 로고
    • Studies on the antitumor bisabolane sesquiterpenoids isolated from Curcuma xanthorrhiza
    • 4085078
    • Itokawa H Hirayama F Funakoshi K Takeya K Studies on the antitumor bisabolane sesquiterpenoids isolated from Curcuma xanthorrhiza Chem Pharm Bull 1985, 33:3488-3492 4085078
    • (1985) Chem Pharm Bull , vol.33 , pp. 3488-3492
    • Itokawa, H.1    Hirayama, F.2    Funakoshi, K.3    Takeya, K.4
  • 37
    • 34447532263 scopus 로고    scopus 로고
    • Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B
    • 10.1093/carcin/bgm005 17234720
    • Chung WY Park JH Kim MJ Kim HO Hwang JK Lee SK Park KK Xanthorrhizol inhibits 12-O-tetradecanoylphorbol-13-acetate-induced acute inflammation and two-stage mouse skin carcinogenesis by blocking the expression of ornithine decarboxylase, cyclooxygenase-2 and inducible nitric oxide synthase through mitogen-activated protein kinases and/or the nuclear factor-kappa B Carcinogenesis 2007, 28:1224-1231 10.1093/carcin/bgm005 17234720
    • (2007) Carcinogenesis , vol.28 , pp. 1224-1231
    • Chung, W.Y.1    Park, J.H.2    Kim, M.J.3    Kim, H.O.4    Hwang, J.K.5    Lee, S.K.6    Park, K.K.7
  • 39
    • 33750231566 scopus 로고    scopus 로고
    • Clinical trials of natural products as chemopreventive agents for prostate cancer
    • 10.1517/13543784.15.10.1191 16989596
    • Bemis DL Katz AE Buttyan R Clinical trials of natural products as chemopreventive agents for prostate cancer Expert Opin Investig Drugs 2006, 15:1191-1200 10.1517/13543784.15.10.1191 16989596
    • (2006) Expert Opin Investig Drugs , vol.15 , pp. 1191-1200
    • Bemis, D.L.1    Katz, A.E.2    Buttyan, R.3
  • 40
    • 38349011007 scopus 로고    scopus 로고
    • Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials
    • 10.1089/ars.2007.1769 18370854
    • Strimpakos AS Sharma RA Curcumin: Preventive and therapeutic properties in laboratory studies and clinical trials Antioxid Redox Signal 2008, 10:511-545 10.1089/ars.2007.1769 18370854
    • (2008) Antioxid Redox Signal , vol.10 , pp. 511-545
    • Strimpakos, A.S.1    Sharma, R.A.2
  • 42
    • 44749093175 scopus 로고    scopus 로고
    • Curcumin: From ancient medicine to current clinical trials
    • 10.1007/s00018-008-7452-4 18324353
    • Hatcher H Planalp R Cho J Torti FM Torti SV Curcumin: From ancient medicine to current clinical trials Cell Mol Life Sci 2008, 65:1631-1652 10.1007/s00018-008-7452-4 18324353
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1631-1652
    • Hatcher, H.1    Planalp, R.2    Cho, J.3    Torti, F.M.4    Torti, S.V.5
  • 43
    • 33845442300 scopus 로고    scopus 로고
    • Chemistry of xanthorrhizol: Synthesis of several bisabolane sesquiterpenoids from xanthorrhizol
    • 10.1016/j.tetlet.2006.11.051
    • Sirat HM Hong NM Jauri MH Chemistry of xanthorrhizol: Synthesis of several bisabolane sesquiterpenoids from xanthorrhizol Tetrahedron Lett 2007, 48:457-460 10.1016/j.tetlet.2006.11.051
    • (2007) Tetrahedron Lett , vol.48 , pp. 457-460
    • Sirat, H.M.1    Hong, N.M.2    Jauri, M.H.3
  • 44
    • 0036710477 scopus 로고    scopus 로고
    • Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs
    • 10.1016/S0006-2952(02)01148-6 12213579
    • Baell JB Huang DCS Prospects for targeting the Bcl-2 family of proteins to develop novel cytotoxic drugs Biochem Pharmacol 2002, 64:851-863 10.1016/S0006-2952(02)01148-6 12213579
    • (2002) Biochem Pharmacol , vol.64 , pp. 851-863
    • Baell, J.B.1    Huang, D.C.S.2
  • 45
    • 33644832665 scopus 로고    scopus 로고
    • Defects of the apoptotic pathway as therapeutic target against cancer
    • 10.1016/j.drup.2005.11.001 16338161
    • Mashima T Tsuruo T Defects of the apoptotic pathway as therapeutic target against cancer Drug Resist Updat 2005, 8:339-3343 10.1016/ j.drup.2005.11.001 16338161
    • (2005) Drug Resist Updat , vol.8 , pp. 339-3343
    • Mashima, T.1    Tsuruo, T.2
  • 47
    • 33746897281 scopus 로고    scopus 로고
    • E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents
    • 10.1158/0008-5472.CAN-05-3725 16849574
    • Russo AJ Magro PG Hu Z Li WW Peters R Mandola J Banerjee D Bertino JR E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents Cancer Res 2006, 66:7253-7260 10.1158/0008-5472.CAN-05-3725 16849574
    • (2006) Cancer Res , vol.66 , pp. 7253-7260
    • Russo, A.J.1    Magro, P.G.2    Hu, Z.3    Li, W.W.4    Peters, R.5    Mandola, J.6    Banerjee, D.7    Bertino, J.R.8
  • 48
    • 33745827711 scopus 로고    scopus 로고
    • Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway
    • 10.1074/jbc.M600746200 16679319
    • Shrivastava A Tiwari M Sinha RA Kumar A Balapure AK Bajpai VK Sharma R Mitra K Tandon A Godbole MM Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway J Biol Chem 2006, 281:19762-19771 10.1074/ jbc.M600746200 16679319
    • (2006) J Biol Chem , vol.281 , pp. 19762-19771
    • Shrivastava, A.1    Tiwari, M.2    Sinha, R.A.3    Kumar, A.4    Balapure, A.K.5    Bajpai, V.K.6    Sharma, R.7    Mitra, K.8    Tandon, A.9    Godbole, M.M.10
  • 49
    • 19344363980 scopus 로고    scopus 로고
    • The mechanism of ellipticine-induced apoptosis and cell cycle arrest in human breast MCF-7 cancer cells
    • 10.1016/j.canlet.2004.09.046 15896464
    • Kuo P Hsu Y Chang C Lin C The mechanism of ellipticine-induced apoptosis and cell cycle arrest in human breast MCF-7 cancer cells Cancer Lett 2005, 223:293-301 10.1016/j.canlet.2004.09.046 15896464
    • (2005) Cancer Lett , vol.223 , pp. 293-301
    • Kuo, P.1    Hsu, Y.2    Chang, C.3    Lin, C.4
  • 50
    • 33748199779 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: Role of caspase and MAPK activation
    • 10.1016/j.ygyno.2006.03.002 16624391
    • Satyan KS Swamy N Dizon DS Singh R Granai CO Brard L Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: Role of caspase and MAPK activation Gynecol Oncol 2006, 103:261-279 10.1016/j.ygyno.2006.03.002 16624391
    • (2006) Gynecol Oncol , vol.103 , pp. 261-279
    • Satyan, K.S.1    Swamy, N.2    Dizon, D.S.3    Singh, R.4    Granai, C.O.5    Brard, L.6
  • 51
    • 33748748204 scopus 로고    scopus 로고
    • Silymarin causes caspases activation and apoptosis in K562 leukemia cells through inactivation of Akt pathway
    • 10.1016/j.tox.2006.07.021
    • Zhong X Zhu Y Lu Q Zhang J Ge Z Zheng S Silymarin causes caspases activation and apoptosis in K562 leukemia cells through inactivation of Akt pathway Toxicol 2006, 227:211-216 10.1016/j.tox.2006.07.021
    • (2006) Toxicol , vol.227 , pp. 211-216
    • Zhong, X.1    Zhu, Y.2    Lu, Q.3    Zhang, J.4    Ge, Z.5    Zheng, S.6
  • 52
    • 30944436851 scopus 로고    scopus 로고
    • Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells
    • 10.1007/s10495-005-2137-z 16215679
    • Kallio A Zheng A Dahllund J Heiskanen K Harkonen P Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells Apoptosis 2005, 10:1395-1410 10.1007/s10495-005-2137-z 16215679
    • (2005) Apoptosis , vol.10 , pp. 1395-1410
    • Kallio, A.1    Zheng, A.2    Dahllund, J.3    Heiskanen, K.4    Harkonen, P.5
  • 53
    • 0036889913 scopus 로고    scopus 로고
    • Apoptosis: Biochemical aspects and clinical implications
    • 10.1016/S0009-8981(02)00297-8 12417095
    • Kiechle FL Zhang X Apoptosis: Biochemical aspects and clinical implications Clin Chim Acta 2002, 326:27-45 10.1016/ S0009-8981(02)00297-8 12417095
    • (2002) Clin Chim Acta , vol.326 , pp. 27-45
    • Kiechle, F.L.1    Zhang, X.2
  • 54
    • 0031773579 scopus 로고    scopus 로고
    • A necessary role for cell shrinkage in apoptosis
    • 10.1016/S0006-2952(98)00225-1 9973175
    • Bortner CD Cidlowski JA A necessary role for cell shrinkage in apoptosis Biochem Pharmacol 1998, 56:1549-1559 10.1016/S0006-2952(98)00225-1 9973175
    • (1998) Biochem Pharmacol , vol.56 , pp. 1549-1559
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 55
    • 0037087501 scopus 로고    scopus 로고
    • Bcl-2 family-mediated apoptotic effects of 3.3′-diindolylmethane (DIM) in human breast cancer cells
    • 10.1016/S0006-2952(02)00856-0 11931841
    • Hong C Firestone GL Bjeldanes LF Bcl-2 family-mediated apoptotic effects of 3.3′-diindolylmethane (DIM) in human breast cancer cells Biochem Pharmacol 2002, 63:1085-1097 10.1016/S0006-2952(02)00856-0 11931841
    • (2002) Biochem Pharmacol , vol.63 , pp. 1085-1097
    • Hong, C.1    Firestone, G.L.2    Bjeldanes, L.F.3
  • 56
    • 0344827168 scopus 로고    scopus 로고
    • Modulation of mitogen-activated protein kinases by 6-nitro-7-hydroxycoumarin mediates apoptosis in renal carcinoma cells
    • 10.1016/j.ejphar.2003.09.035 14642781
    • Finn G Creaven B Egan D Modulation of mitogen-activated protein kinases by 6-nitro-7-hydroxycoumarin mediates apoptosis in renal carcinoma cells Eur J Pharmacol 2003, 481:159-167 10.1016/j.ejphar.2003.09.035 14642781
    • (2003) Eur J Pharmacol , vol.481 , pp. 159-167
    • Finn, G.1    Creaven, B.2    Egan, D.3
  • 57
    • 0034930391 scopus 로고    scopus 로고
    • Signaling pathways and effector mechanisms preprogrammed cell death
    • 10.1016/S0968-0896(01)00041-4 11408158
    • Blatt NB Glinck GD Signaling pathways and effector mechanisms preprogrammed cell death Bioorg Med Chem 2001, 9:1371-1384 10.1016/ S0968-0896(01)00041-4 11408158
    • (2001) Bioorg Med Chem , vol.9 , pp. 1371-1384
    • Blatt, N.B.1    Glinck, G.D.2
  • 58
    • 34347230544 scopus 로고    scopus 로고
    • Sulforhodamine B colorimetric assay for cytotoxicity screening
    • 10.1038/nprot.2006.179 17406391
    • Vichai V Kirtikara K Sulforhodamine B colorimetric assay for cytotoxicity screening Nat Protoc 2006, 1:1112-1116 10.1038/ nprot.2006.179 17406391
    • (2006) Nat Protoc , vol.1 , pp. 1112-1116
    • Vichai, V.1    Kirtikara, K.2
  • 59
    • 50649125126 scopus 로고    scopus 로고
    • Anticancer properties of 2-piperidyl analogues of the natural indole phytoalexin 1-methoxyspirobrassinol
    • 10.1159/000152027
    • Mezencev R Kutschy P Salayová A Curillová Z Mojzis J Pilátová M McDonald J Anticancer properties of 2-piperidyl analogues of the natural indole phytoalexin 1-methoxyspirobrassinol Chemother 2008, 54:372-378 10.1159/000152027
    • (2008) Chemother , vol.54 , pp. 372-378
    • Mezencev, R.1    Kutschy, P.2    Salayová, A.3    Curillová, Z.4    Mojzis, J.5    Pilátová, M.6    McDonald, J.7
  • 61
    • 43149117910 scopus 로고    scopus 로고
    • Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines, Mcl-1 inactivation
    • 10.1093/jnci/djn076 18398104
    • Kang MH Wan Z Kang YH Sposto R Reynolds CP Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines, Mcl-1 inactivation J Natl Cancer Inst 2008, 100:580-595 10.1093/jnci/djn076 18398104
    • (2008) J Natl Cancer Inst , vol.100 , pp. 580-595
    • Kang, M.H.1    Wan, Z.2    Kang, Y.H.3    Sposto, R.4    Reynolds, C.P.5
  • 62
    • 53549093298 scopus 로고    scopus 로고
    • Research on the antitumor effect of ginsenoside Rg3 in B16 melanoma cells
    • 10.1097/CMR.0b013e32830b3536 18781130
    • Chen J Peng H Ou-Yang X He X Research on the antitumor effect of ginsenoside Rg3 in B16 melanoma cells Melanoma Res 2008, 18:322-329 10.1097/CMR.0b013e32830b3536 18781130
    • (2008) Melanoma Res , vol.18 , pp. 322-329
    • Chen, J.1    Peng, H.2    Ou-Yang, X.3    He, X.4


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