Toll-like receptors and atherosclerosis

Medicinski Glasnik

Volumn 6, Issue 1, 2009, Pages 23-31

  Džumhur, Andrea ^a   Alkhamis, Tamara ^b   Džumhur, Edo ^c   Džijan, Snježana ^b   Barbić, Jerko ^a  

^a UNIVERSITY HOSPITAL OSIJEK   (Croatia)

^b JOSIP JURAJ STROSSMAYER UNIVERSITY OF OSIJEK   (Croatia)

^c General Hospital Vukovar   (Croatia)

Author keywords

Atherosclerosis; Gene polymorphism; Inflammation; Toll like receptors

Indexed keywords

B7 ANTIGEN; CHEMOKINE; CORTICOSTERONE; CYTOKINE; INTERLEUKIN 12; STEROID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ACUTE CORONARY SYNDROME; ACUTE DISEASE; ADRENAL GLAND; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BACTERIAL INFECTION; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; DISEASE COURSE; ENDOTOXEMIA; GENETIC POLYMORPHISM; HEART INFARCTION; HUMAN; INFLAMMATION; PARASITOSIS; REVIEW; STEROID RELEASE; VIRUS INFECTION;

EID: 60049089404     PISSN: 18400132     EISSN: 18402445     Source Type: Journal    
DOI: None     Document Type: Review

References (43)

1. Sabroe I, Parker LC, Dower SK, Whyte MK. The role of TLR activation in inflammation. J Pathol 2008; 214:126-35.
2. Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ. Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 2002; 105:1158-61.
3. Bornstein SR, Moraweitz H, Kazemi MR, Grunfeld C and Feingold KR. Toll-Like Receptors, Endocrine Stress Response, and Arteriosclerosis. Arterioscler Thromb Vase Biol 2005; 25:el35.
4. Ross R. Atherosclerosis- an inflammatory disease. N Engl J Med 1999; 340:115-26.
5. Vcev A, Nakić D, Mrden A, Mirat J, Balen S, Ruzić A, Peršić V, Soldo I, Matijević M, Barbić J, Matijević V, Bozić D, Radanović B. Helicobacter pylori infection and coronary artery disease. Coll Antropol 2007; 31:757-60.
6. Reiner Ž, Gamulin S. Ateroskleroza. In: Gamulin S, Marǔsić M, Kovač Z, editors. Patofiziologija. Zagreb: Medicinska naklada, 2002:72-6.
7. Fuster VBL, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992; 326:242-50, 310-8.
8. Fuster V. Mechanisms leading to myocardial infarction: insights from studies of vascular biology. Circulation 1994; 90:2126-46.
9. Barbic J, Leef MF, Burns DL, Shahin RD. Role of gamma interferon in natural clearance of Bordetella pertussis infection. Infection and Immunity 1997; 65:4904-8.
10. Medzhitov R and Janeway C. Innate immunity. N Engl J Med 2000; 343:338-44.
11. Hansson GK, Libby P, Schönbeck U, Yan ZQ. Innate and adaptive immunity in the pathogenesis of atherosclerosis. Circ Res 2002; 91:281-91.
12. Mitchell JA, Paul-Clark MJ, Clarke GW, McMaster SK and Cartwright N. Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease. J Endocrinology 2007; 193:323-30.
13. Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, Hoshino K, Takeuchi O, Kobayashi M, Fujita T, Takeda K, Akira S. Essential role for TIRAP in activation of the signaling cascade shared by TLR2 and TLR4. Nature 2002; 420:324-9.
14. Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Takeda K, Akira S. Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 2003; 301:640-3.
15. Yamamoto M, Sato S, Hemmi H, Uematsu S, Hoshino K, Kaisho T, Takeuchi O, Takeda K, Akira S. TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-inde- pendent signaling pathway. Nat Immunol 2003; 4:1144-50.
16. Toshchakov V, Jones BW, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN. TLR4, but not TLR2, mediates IFN-beta-induced STATlalpha/ beta-dependent gene expression in macrophages. Nature Immunology 2002; 3:392-8.
17. Gewritz AT, Nasvas TA, Lyons S, Godowski PJ, Madara JL. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. J Immunol 2001; 167:1882-5.
18. Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001; 410:1009-103.
19. Wu XY, Xiang LX, Huang L, Jin Y, Shao JZ. Characterization, expression and evolution analysis of Toll-like receptor 1 gene in pufferfish (Tetraodon nigroviridis). Int J Immunogenet 2008; 35:215- 25.
20. Vakharia K, Hinson JP. Lipopolysaccharide directly stimulates Cortisol secretion by human adrenal cells by a cyclooxygenase-dependent mechanism. Endocrinology 2005; 146:1398-402.
21. Tran N, Koch A, Berkels R, Boehm O, Zacharowski PA, Baurngarten G, Knuefermann P, Schott M, Kanczkowski W, Bornstein SR, Lightman SL, Zacharowski K. Toll like receptor 9 expression in murine and human adrenal glands and possible implications during inflammation. J Clin Endocrinol 2007; 92:2773-83.
22. th edition. Amsterdam; Boston: Elsevier; Academic Press; 2006:889-97.
23. Wiedemann CJ, Kiechl S. Dunzendorfer S, Schartzberger P, Egger G, Oberhollenzer F, Willeit Jl. Association of endotoxemia with carotid atherosclerosis and cardiovascular disease. Prospective results from Bruneck study. J Am Coll Cardiol 1999; 34:1975-81.
24. Pajkrt D, Lerch PG, van der Poll T, Levi M, Illi M, Doran JE, Arnet B, van den Ende A, ten Cate JW, van Deventer SJ. Differential effects of reconstituted high-density lipoprotein on coagulation, fibrinolysis and platelet activation during human endotoxemia. Thromb Haemost 1997; 77:303-7.
25. Kazemi MR, Mc Donald CM, Shigenag JK, Grunfeld C, Feingold KR. Adipocyte fatty acid- binding protein expression and lipid accumulation is increased during activation of murine macrophages by toll-like receptors. Arterioscler Thromb Vase Biol 2005; 25:1220-4.
26. Miller YI, Viriyakosol S, Worrall DS, Boullier A, Butler S, Witztum JL. Toll-like receptor 4-dependent and independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages. Arterioscler Thromb Vase Biol 2005; 25:1213-9.
27. Hoek RM, Ruuls SR, Murphy CA, Wright GJ, Goddard R, Zurawski SM, Blom B, Homola ME, Streit WJ, Brown MH, Barclay AN, Sedgwick JD. Down-regulation of the macrophage lineage through interaction with 0X2 (CD200). Science 2000; 290:1768-71.
28. Häcker H, Redecke V, Blagoev B, Kratchmarova 1, Hsu LC, Wang GG, Kamps MP, Raz E, Wagner H, Häcker G, Mann M, Karin M. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 2006; 12; 439:204-7.
29. Vabulas RM, Wagner H, Schild H. Heat shock proteins as ligands of toll-like receptors. Curr Top Microbiol Immunol 2002; 270:169-84.
30. Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002; 418:191-5
31. Michelsen KS, Wong MH, Shah P, Zhang W, Yano J, Doherty TM, Akira S, Rajavashisth TB, Arditi M. Lack of Toll like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc Natl Acad Sci USA 2004; 101:10679-84.
32. Shishido T, Nozaki N, Yamaguchi S, Shibata Y, Nitobe J, Miyamoto T, Takahashi H, Arimoto T, Maeda K, Yamakawa M, Takeuchi O, Akira S, Takeishi Y, Kubota I. Toll-like Receptor-2 Modulates Remodeling After Myocardial Infarction. Circulation 2003; 108:2905-10.
33. Xu XH, Shah PK, Faure E, Equils O, Thomas L, Fishbein MC, Luthringer D, Xu XP, Rajavashisth TB, Yano J, Kaul S, Arditi M. Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation 2001; 104:3103-8.
34. Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R. Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2001; 2:947-50.
35. Methe H, Zimmer E, Grimm C, Nabauer M, Koglin J. Evidence for a role of toll-like receptor 4 in development of chronic allograft rejection after cardiac transplantation. Transplantation 2004; 78:1324-31.
36. Bjorckbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW. Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways. Net Med 2004; 10:416-21.
37. Balistreri CR, Caruso M, Franceschi C, Caruso C. Roll of Toll-like Receptor 4 in Acute Myocardial Infarction and Longevity. JAMA 2004; 292:2339-40.
38. Yang IA, Holloway JW, Ye S. TLR4 Asp 299Gly polymorphism is not associated with coronary artery stenosis. Atherosclerosis 2003; 170:187-90.
39. Netea MG, Hijmans A, Van Wissen S, Smilde TJ, Trip MD, Kullberg BJ, de Boo T, Van der Meer JW, Kastelein JJ, Stalenhoef AF. Toll-like receptor 4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia. Eur J Clin Ivest 2004; 34:94-9.
40. Oyama J, Blais C.Jr, Liu X, Pu M, Kobzik L, Kelly RA, Bourcier T. Reduced myocardial ischemia-reperfusion injuri in Toll-like receptror 4- deficient mice. Circulation 2004; 109:784-9.
41. Lin YC, Chang YM, Yu JM, Yen JH, Chang JG, Hu CJ. Toll-like receptor 4 gene C119A but not Asp299Gly polymorphism is associated with ischemic stroke among ethnic Chinese Taiwan. Atherosclerosis 2005; 180:305-9.
42. Hamann L, Gomma A, Schroder NWJ, Stamme C, Glaeser C, Schultz S, Gross M, Anker SD, Fox K, Schumann RR. A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis. J Mol Med 2005; 83:478-85.
43. Labrum R, Bevan S, Sitzer M, Lorenz M, Markus HS. Toll receptor polymorphisms and carotid artery intima-media thickness. Stroke 2007; 38:1179-84.