-
1
-
-
0003964363
-
-
American Cancer Society, Atlanta: American Cancer Society
-
American Cancer Society Cancer Facts & Figures (2008). Atlanta: American Cancer Society.
-
(2008)
Cancer Facts & Figures
-
-
-
2
-
-
0026605632
-
In vitro paracrine regulation of human keratinocyte growth by fibroblast derived insulin-like growth factors
-
Barreca A, De Luca M, Del Monte P, Bondanza S, Damonte G, Cariola G et al. (1992) In vitro paracrine regulation of human keratinocyte growth by fibroblast derived insulin-like growth factors. J Cell Physiol 151:262-8
-
(1992)
J Cell Physiol
, vol.151
, pp. 262-268
-
-
Barreca, A.1
De Luca, M.2
Del Monte, P.3
Bondanza, S.4
Damonte, G.5
Cariola, G.6
-
3
-
-
0030980895
-
Overexpression of the insulin-like growth factor-1 induces hyperplasia, dermal abnormalities and spontaneous tumor formation in transgenic mice
-
Bol DK, Kigucji K, Gimenez-Conti I, Rupp T, DiGiovanni J (1997) Overexpression of the insulin-like growth factor-1 induces hyperplasia, dermal abnormalities and spontaneous tumor formation in transgenic mice. Oncogene 14:1725-34
-
(1997)
Oncogene
, vol.14
, pp. 1725-1734
-
-
Bol, D.K.1
Kigucji, K.2
Gimenez-Conti, I.3
Rupp, T.4
DiGiovanni, J.5
-
4
-
-
13944270339
-
Senescent cells, tumor suppression and organismal aging: Good citizens, bad neighbors
-
Campisi J (2005) Senescent cells, tumor suppression and organismal aging: good citizens, bad neighbors. Cell 120:513-22
-
(2005)
Cell
, vol.120
, pp. 513-522
-
-
Campisi, J.1
-
5
-
-
1642555946
-
Resistance of UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53
-
Chaturvedi V, Qin JZ, Stennett L, Choubey D, Nickoloff BJ (2004) Resistance of UV-induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53. J Cell Physio 198:100-109
-
(2004)
J Cell Physio
, vol.198
, pp. 100-109
-
-
Chaturvedi, V.1
Qin, J.Z.2
Stennett, L.3
Choubey, D.4
Nickoloff, B.J.5
-
6
-
-
24044494290
-
Knockdown of p53 levles in human keratinocytes accelerated Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis
-
Chaturvedi V, Sitailo LA, Qin JZ, Bodner B, Denning MF, Curry J et al. (2005) Knockdown of p53 levles in human keratinocytes accelerated Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 24:5299-312
-
(2005)
Oncogene
, vol.24
, pp. 5299-5312
-
-
Chaturvedi, V.1
Sitailo, L.A.2
Qin, J.Z.3
Bodner, B.4
Denning, M.F.5
Curry, J.6
-
7
-
-
24344463518
-
Decreased incidence of non-melanoma skin cancer in patients with type 2 diabetes mellitus using insulin: A pilot study
-
Chuang T-Y, Lewis DA, Spandau DF (2005) Decreased incidence of non-melanoma skin cancer in patients with type 2 diabetes mellitus using insulin: a pilot study. Br J Derm 153:552-7
-
(2005)
Br J Derm
, vol.153
, pp. 552-557
-
-
Chuang, T.-Y.1
Lewis, D.A.2
Spandau, D.F.3
-
8
-
-
34447543913
-
Cellular senescence in cancer and aging
-
Collado M, Blasco MA, Serrao M (2007) Cellular senescence in cancer and aging. Cell 130:223-31
-
(2007)
Cell
, vol.130
, pp. 223-231
-
-
Collado, M.1
Blasco, M.A.2
Serrao, M.3
-
9
-
-
38149136430
-
The role of recombinant human insulin-like growth factor-I in treating children with short stature
-
Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society
-
Collett-Solberg PF, Misra M, Drug and Therapeutics Committee of the Lawson Wilkins Pediatric Endocrine Society (2008) The role of recombinant human insulin-like growth factor-I in treating children with short stature. J Clin Endocrin Metabol 93:10-18
-
(2008)
J Clin Endocrin Metabol
, vol.93
, pp. 10-18
-
-
Collett-Solberg, P.F.1
Misra, M.2
-
10
-
-
0031053387
-
Ultraviolet B dose influences the induction of apoptosis and p53 in human keratinocytes
-
Cotton J, Spandau DF (1997) Ultraviolet B dose influences the induction of apoptosis and p53 in human keratinocytes. Radiat Res 147:148-55
-
(1997)
Radiat Res
, vol.147
, pp. 148-155
-
-
Cotton, J.1
Spandau, D.F.2
-
11
-
-
34548544452
-
Nonablative tissue remodeling and photorejuvenation
-
DeHoratius DM, Dover JS (2007) Nonablative tissue remodeling and photorejuvenation. Clin Dermatol 25:474-9
-
(2007)
Clin Dermatol
, vol.25
, pp. 474-479
-
-
DeHoratius, D.M.1
Dover, J.S.2
-
12
-
-
0034653704
-
Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion
-
DiGiovanni J, Bol DK, Wilker E, Beltran L, Carbajal S, Moats S et al. (2000) Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion. Cancer Res 60:1561-70
-
(2000)
Cancer Res
, vol.60
, pp. 1561-1570
-
-
DiGiovanni, J.1
Bol, D.K.2
Wilker, E.3
Beltran, L.4
Carbajal, S.5
Moats, S.6
-
13
-
-
0141792500
-
Novel mechanisms of sublethal oxidant toxicity: Induction of premature senescence in human fibroblasts confer tumor promoter activity
-
Dilley T, Bowden G, Chen Q (2003) Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confer tumor promoter activity. Exp Cell Res 290:38-48
-
(2003)
Exp Cell Res
, vol.290
, pp. 38-48
-
-
Dilley, T.1
Bowden, G.2
Chen, Q.3
-
14
-
-
0029047362
-
A biomarkers that identifies senescent human cells in culture and in aging skin in vivo
-
Dimiri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C et al. (1995) A biomarkers that identifies senescent human cells in culture and in aging skin in vivo. Pro Natl Acad Sci USA 92:9363-7
-
(1995)
Pro Natl Acad Sci USA
, vol.92
, pp. 9363-9367
-
-
Dimiri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
-
15
-
-
35548929551
-
Declining p53 function in the aging process: A possible mechanism for the increased tumor incidence in older population
-
Feng Z, Hu W, Teresky AK, Hernando E, Cordon-Cardo C, Levine AJ (2007) Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older population. Proc Natl Acad Sci USA 104:16633-8
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 16633-16638
-
-
Feng, Z.1
Hu, W.2
Teresky, A.K.3
Hernando, E.4
Cordon-Cardo, C.5
Levine, A.J.6
-
16
-
-
0027295499
-
Failure of senescent human fibroblasts to express insulin-like growth factor-1 gene
-
Ferber A, Chang C, Sells C, Ptasznik A, Cristofalo V, Hubbard K et al. (1993) Failure of senescent human fibroblasts to express insulin-like growth factor-1 gene. J Biol Chem 268:17883-8
-
(1993)
J Biol Chem
, vol.268
, pp. 17883-17888
-
-
Ferber, A.1
Chang, C.2
Sells, C.3
Ptasznik, A.4
Cristofalo, V.5
Hubbard, K.6
-
17
-
-
33646174323
-
Current treatments of actinic keratosis
-
Gold MH, Nestor MS (2006) Current treatments of actinic keratosis. J Drugs Dermatol 5(Suppl 2):17-25
-
(2006)
J Drugs Dermatol
, vol.5
, Issue.SUPPL. 2
, pp. 17-25
-
-
Gold, M.H.1
Nestor, M.S.2
-
18
-
-
22144477243
-
Reduced insulin/IGF-1 signalling and human longevity
-
Heemst DV, Beekman M, Mooijaart SP, Heijmans BT, Brandt BW, Zwaan BJ et al. (2005) Reduced insulin/IGF-1 signalling and human longevity. Aging Cell 4:79-85
-
(2005)
Aging Cell
, vol.4
, pp. 79-85
-
-
Heemst, D.V.1
Beekman, M.2
Mooijaart, S.P.3
Heijmans, B.T.4
Brandt, B.W.5
Zwaan, B.J.6
-
20
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC et al. (2003) IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 21:182-7
-
(2003)
Nature
, vol.21
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Even, P.C.6
-
21
-
-
34249818455
-
Senescence as an anticancer mechanism
-
Hornsby PJ (2007) Senescence as an anticancer mechanism. J Clin Oncol 14:1852-7
-
(2007)
J Clin Oncol
, vol.14
, pp. 1852-1857
-
-
Hornsby, P.J.1
-
22
-
-
28844474827
-
Anti-apoptotic and anti-senescent effects of Klotho on vascular endothelial cells
-
Ikushima M, Rakugi H, Ishidawa K, Maedawa Y, Yamamoto K, Ohta J et al. (2006) Anti-apoptotic and anti-senescent effects of Klotho on vascular endothelial cells. Biochem Biophys Res Commun 339:827-32
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 827-832
-
-
Ikushima, M.1
Rakugi, H.2
Ishidawa, K.3
Maedawa, Y.4
Yamamoto, K.5
Ohta, J.6
-
25
-
-
0036829090
-
Cancer and aging: A model for the cancer promoting effects of the aging stroma
-
Krtolica A, Campisi J (2002) Cancer and aging: a model for the cancer promoting effects of the aging stroma. Int J Biochem Cell Biol 34:1401-14
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1401-1414
-
-
Krtolica, A.1
Campisi, J.2
-
26
-
-
0035834121
-
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
-
Krtolica A, Parrinello S, Lockett S, Desprez P-Y, Campisi J (2001) Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci USA 98:12072-12077
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12072-12077
-
-
Krtolica, A.1
Parrinello, S.2
Lockett, S.3
Desprez, P.-Y.4
Campisi, J.5
-
27
-
-
0032939970
-
Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation
-
Kuhn C, Kumar M, Hurwitz SA, Cotton J, Spandau DF (1999) Activation of the insulin-like growth factor-1 receptor promotes the survival of human keratinocytes following ultraviolet B irradiation. Int J Cancer 80:431-8
-
(1999)
Int J Cancer
, vol.80
, pp. 431-438
-
-
Kuhn, C.1
Kumar, M.2
Hurwitz, S.A.3
Cotton, J.4
Spandau, D.F.5
-
28
-
-
24944481544
-
Suppression of aging in mice by the hormone Klotho
-
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P et al. (2005) Suppression of aging in mice by the hormone Klotho. Science 309:1829-33
-
(2005)
Science
, vol.309
, pp. 1829-1833
-
-
Kurosu, H.1
Yamamoto, M.2
Clark, J.D.3
Pastor, J.V.4
Nandi, A.5
Gurnani, P.6
-
29
-
-
33746171325
-
Aberrant NF-κB activity in HaCaT cells alters their response to UVB signaling
-
Lewis DA, Hengeltraub S, Gao F, Leivant MA, Spandau DF (2006) Aberrant NF-κB activity in HaCaT cells alters their response to UVB signaling. J Invest Dermatol 126:1885-92
-
(2006)
J Invest Dermatol
, vol.126
, pp. 1885-1892
-
-
Lewis, D.A.1
Hengeltraub, S.2
Gao, F.3
Leivant, M.A.4
Spandau, D.F.5
-
30
-
-
34247628480
-
UVB activation of NF-κB in normal human keratinocytes occurs via a unique mechanism
-
Lewis DA, Spandau DF (2007) UVB activation of NF-κB in normal human keratinocytes occurs via a unique mechanism. Arch Dermatol Res 299:93-101
-
(2007)
Arch Dermatol Res
, vol.299
, pp. 93-101
-
-
Lewis, D.A.1
Spandau, D.F.2
-
31
-
-
40649118792
-
UVB-induced activation of NF kappa B is regulated by the IGF-1R and dependent on p38 MAPK
-
Lewis DA, Spandau DF (2008) UVB-induced activation of NF kappa B is regulated by the IGF-1R and dependent on p38 MAPK. J Invest Dermatol 128:1022-9
-
(2008)
J Invest Dermatol
, vol.128
, pp. 1022-1029
-
-
Lewis, D.A.1
Spandau, D.F.2
-
32
-
-
44949201233
-
UVB-induced senescence in human keratinocytes requires a functional IGF-1R and p53
-
Lewis DA, Yi Q, Travers JB, Spandau DF (2008) UVB-induced senescence in human keratinocytes requires a functional IGF-1R and p53. Mol Biol Cell 19:1349-53
-
(2008)
Mol Biol Cell
, vol.19
, pp. 1349-1353
-
-
Lewis, D.A.1
Yi, Q.2
Travers, J.B.3
Spandau, D.F.4
-
33
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I and type 1 IGF receptor
-
Lui JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A (1993) Mice carrying null mutations of the genes encoding insulin-like growth factor I and type 1 IGF receptor. Cell 75:59-72
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Lui, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
34
-
-
33744795221
-
Long-term health risk to the skin of ultraviolet radiation
-
MacKie RM (2006) Long-term health risk to the skin of ultraviolet radiation. Prog Biophys Mol Biol 92:92-6
-
(2006)
Prog Biophys Mol Biol
, vol.92
, pp. 92-96
-
-
MacKie, R.M.1
-
35
-
-
32144442585
-
Treatment of hypertrophic scars and keloids with a radiofrequency device: A study of collagen effects
-
Meshkinpour A, Ghasri P, Pope K, Lyubovitsky JG, Risteli J, Krasieva TB et al. (2005) Treatment of hypertrophic scars and keloids with a radiofrequency device: a study of collagen effects. Lasers Surg Med 37:343-9
-
(2005)
Lasers Surg Med
, vol.37
, pp. 343-349
-
-
Meshkinpour, A.1
Ghasri, P.2
Pope, K.3
Lyubovitsky, J.G.4
Risteli, J.5
Krasieva, T.B.6
-
36
-
-
13944260728
-
Stromal-epithelial interactions in aging and cancer: Senescent fibroblasts alter epithelial cell differentiation
-
Parinello S, Coppe J-P, Krtolica A, Campisi J (2005) Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation. J Cell Sci 118:485-96
-
(2005)
J Cell Sci
, vol.118
, pp. 485-496
-
-
Parinello, S.1
Coppe, J.-P.2
Krtolica, A.3
Campisi, J.4
-
37
-
-
0037007427
-
Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes
-
Qin JZ, Chaturvedi V, Denning MF, Bacon P, Panella J, Choubey D et al. (2002) Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes. Oncogene 21:2991-3002
-
(2002)
Oncogene
, vol.21
, pp. 2991-3002
-
-
Qin, J.Z.1
Chaturvedi, V.2
Denning, M.F.3
Bacon, P.4
Panella, J.5
Choubey, D.6
-
39
-
-
33645224054
-
Insulin-like growth factor receptor signaling regulates skin development and inhibits skin keratinocyte differentiation
-
Sadagurski M, Yakar S, Weingarten G, Holzenberger M, Rhodes C, Breikreutz D et al. (2006) Insulin-like growth factor receptor signaling regulates skin development and inhibits skin keratinocyte differentiation. Mol Cell Biol 26:2675-87
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2675-2687
-
-
Sadagurski, M.1
Yakar, S.2
Weingarten, G.3
Holzenberger, M.4
Rhodes, C.5
Breikreutz, D.6
-
40
-
-
33846874575
-
The role of the IGF1 system in cancer growth and metastasis: Overview and recent highlights
-
Samani AA, Shoshana Y, LeRoith D, Brodt P (2005) The role of the IGF1 system in cancer growth and metastasis: overview and recent highlights. Endocr Rev 28:20-47
-
(2005)
Endocr Rev
, vol.28
, pp. 20-47
-
-
Samani, A.A.1
Shoshana, Y.2
LeRoith, D.3
Brodt, P.4
-
41
-
-
0026757921
-
Expression of growth hormone receptor, insulin-like growth factor 1 (IGF-1) and IGF-1 receptor mRNA and proteins in human skin
-
Tavakkol A, Elder JT, Griffiths CE, Cooper KD, Talwar H, Fisher GJ et al. (1992) Expression of growth hormone receptor, insulin-like growth factor 1 (IGF-1) and IGF-1 receptor mRNA and proteins in human skin. J Invest Dermatol 99:343-9
-
(1992)
J Invest Dermatol
, vol.99
, pp. 343-349
-
-
Tavakkol, A.1
Elder, J.T.2
Griffiths, C.E.3
Cooper, K.D.4
Talwar, H.5
Fisher, G.J.6
-
42
-
-
0035144754
-
Childhood sun exposure as a risk factor for melanoma: A systematic review of epidemiologic studies
-
Whiteman DC, Whiteman CA, Green AC (2001) Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies. Cancer Causes Control 12:69-82
-
(2001)
Cancer Causes Control
, vol.12
, pp. 69-82
-
-
Whiteman, D.C.1
Whiteman, C.A.2
Green, A.C.3
-
43
-
-
0033059976
-
Enhancement for susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice
-
Wilker E, Bol D, Kiguchi K, Rupp T, Beltran L, Di Giovanni J (1999) Enhancement for susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice. Mol Carcinog 25:122-131
-
(1999)
Mol Carcinog
, vol.25
, pp. 122-131
-
-
Wilker, E.1
Bol, D.2
Kiguchi, K.3
Rupp, T.4
Beltran, L.5
Di Giovanni, J.6
-
44
-
-
0000055057
-
Pleiotropy, natural selection and the evolution of senescence
-
Williams GC (1957) Pleiotropy, natural selection and the evolution of senescence. Evolution 11:398-411
-
(1957)
Evolution
, vol.11
, pp. 398-411
-
-
Williams, G.C.1
-
45
-
-
29044437964
-
Aged human skin removes UVB-induced pyrimidine dimmers from the epidermis more slowly than younger adult skin in vivo
-
Yamada M, Udono M, Hori M, Hirose R, Sato S, Mori T et al. (2006) Aged human skin removes UVB-induced pyrimidine dimmers from the epidermis more slowly than younger adult skin in vivo. Arch Dermatol Res 297:294-302
-
(2006)
Arch Dermatol Res
, vol.297
, pp. 294-302
-
-
Yamada, M.1
Udono, M.2
Hori, M.3
Hirose, R.4
Sato, S.5
Mori, T.6
|