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Volumn 114, Issue 1-3, 2009, Pages 224-231

The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population

Author keywords

Gene environment interaction; Major depressive disorder; Negative life events; Objective social supports; Polymorphism; Serotonin

Indexed keywords

SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER;

EID: 59849095464     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2008.07.012     Document Type: Article
Times cited : (82)

References (52)
  • 3
    • 0036428848 scopus 로고    scopus 로고
    • Analysis of structural polymorphisms and C-1018G promoter variant of the 5-HT (1A) receptor gene as putative risk factors in major depression
    • Arias B., Arranz M.J., Gasto C., Catalan R., Pintor L., Gutierrez B., Kerwin R.W., and Fananas L. Analysis of structural polymorphisms and C-1018G promoter variant of the 5-HT (1A) receptor gene as putative risk factors in major depression. Mol. Psychiatry 7 (2002) 930-932
    • (2002) Mol. Psychiatry , vol.7 , pp. 930-932
    • Arias, B.1    Arranz, M.J.2    Gasto, C.3    Catalan, R.4    Pintor, L.5    Gutierrez, B.6    Kerwin, R.W.7    Fananas, L.8
  • 4
    • 17744397364 scopus 로고    scopus 로고
    • Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram
    • Arias B., Catalán R., Gastó C., Gutiérrez B., and Fañanás L. Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram. J. Psychopharmacol. 19 (2005) 166-167
    • (2005) J. Psychopharmacol. , vol.19 , pp. 166-167
    • Arias, B.1    Catalán, R.2    Gastó, C.3    Gutiérrez, B.4    Fañanás, L.5
  • 8
    • 0030702864 scopus 로고    scopus 로고
    • Cognitive impairment and social distress as different pathways to depression in the elderly: a cross-sectional study
    • Cervilla J.A., and Prince M.J. Cognitive impairment and social distress as different pathways to depression in the elderly: a cross-sectional study. Int. J. Geriatr. Psychiatry 12 (1997) 995-1000
    • (1997) Int. J. Geriatr. Psychiatry , vol.12 , pp. 995-1000
    • Cervilla, J.A.1    Prince, M.J.2
  • 9
    • 34547478713 scopus 로고    scopus 로고
    • The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort
    • PREDICT Study Core Group
    • Cervilla J.A., Molina E., Rivera M., Torres-González F., Bellón J.A., Moreno B., Luna J.D., Lorente J.A., Mayoral F., King M., Nazareth I., Gutiérrez B., and PREDICT Study Core Group. The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: evidence from the Spanish PREDICT-Gene cohort. Mol. Psychiatry 12 (2007) 748-755
    • (2007) Mol. Psychiatry , vol.12 , pp. 748-755
    • Cervilla, J.A.1    Molina, E.2    Rivera, M.3    Torres-González, F.4    Bellón, J.A.5    Moreno, B.6    Luna, J.D.7    Lorente, J.A.8    Mayoral, F.9    King, M.10    Nazareth, I.11    Gutiérrez, B.12
  • 10
    • 34250852332 scopus 로고    scopus 로고
    • No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: results from two community surveys
    • Chipman P., Jorm A.F., Prior M., Sanson A., Smart D., Tan X., and Easteal S. No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: results from two community surveys. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144 (2007) 561-565
    • (2007) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.144 , pp. 561-565
    • Chipman, P.1    Jorm, A.F.2    Prior, M.3    Sanson, A.4    Smart, D.5    Tan, X.6    Easteal, S.7
  • 14
    • 13444280555 scopus 로고    scopus 로고
    • The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression
    • Gillespie N.A., Whitfield J.B., Williams B., Heath A.C., and Martin N.G. The relationship between stressful life events, the serotonin transporter (5-HTTLPR) genotype and major depression. Psychol. Med. 35 (2005) 101-111
    • (2005) Psychol. Med. , vol.35 , pp. 101-111
    • Gillespie, N.A.1    Whitfield, J.B.2    Williams, B.3    Heath, A.C.4    Martin, N.G.5
  • 17
    • 0023808877 scopus 로고
    • Social relationships and health
    • House J.S., Landis K.R., and Umberson D. Social relationships and health. Science 241 (1988) 540-545
    • (1988) Science , vol.241 , pp. 540-545
    • House, J.S.1    Landis, K.R.2    Umberson, D.3
  • 19
    • 33748324559 scopus 로고    scopus 로고
    • Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression
    • Jacobs N., Kenis G., Peeters F., Derom C., Vlietinck R., and van Os J. Stress-related negative affectivity and genetically altered serotonin transporter function: evidence of synergism in shaping risk of depression. Arch. Gen. Psychiatry 63 (2006) 989-996
    • (2006) Arch. Gen. Psychiatry , vol.63 , pp. 989-996
    • Jacobs, N.1    Kenis, G.2    Peeters, F.3    Derom, C.4    Vlietinck, R.5    van Os, J.6
  • 21
    • 0035118875 scopus 로고    scopus 로고
    • Serotonin transporter polymorphisms: no association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia
    • Kaiser R., Tremblay P.B., Schmider J., Henneken M., Dettling M., Müller-Oerlinghausen B., Uebelhack R., Roots I., and Brockmöller J. Serotonin transporter polymorphisms: no association with response to antipsychotic treatment, but associations with the schizoparanoid and residual subtypes of schizophrenia. Mol. Psychiatry 6 (2001) 179-185
    • (2001) Mol. Psychiatry , vol.6 , pp. 179-185
    • Kaiser, R.1    Tremblay, P.B.2    Schmider, J.3    Henneken, M.4    Dettling, M.5    Müller-Oerlinghausen, B.6    Uebelhack, R.7    Roots, I.8    Brockmöller, J.9
  • 22
    • 33846160926 scopus 로고    scopus 로고
    • Molecular genetics of bipolar disorder and depression
    • Kato T. Molecular genetics of bipolar disorder and depression. Psychiatry Clin. Neurosci. 61 (2007) 3-19
    • (2007) Psychiatry Clin. Neurosci. , vol.61 , pp. 3-19
    • Kato, T.1
  • 25
    • 0036304285 scopus 로고    scopus 로고
    • Toward a comprehensive developmental model for major depression in women
    • Kendler K.S., Gardner C.O., and Prescott C.A. Toward a comprehensive developmental model for major depression in women. Am. J. Psychiatry 159 (2002) 1133-1145
    • (2002) Am. J. Psychiatry , vol.159 , pp. 1133-1145
    • Kendler, K.S.1    Gardner, C.O.2    Prescott, C.A.3
  • 26
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication
    • Kendler K.S., Kuhn J.W., Vittum J., Prescott C.A., and Riley B. The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch. Gen. Psychiatry 62 (2005) 529-535
    • (2005) Arch. Gen. Psychiatry , vol.62 , pp. 529-535
    • Kendler, K.S.1    Kuhn, J.W.2    Vittum, J.3    Prescott, C.A.4    Riley, B.5
  • 27
    • 0026810828 scopus 로고
    • Social support, depressed mood, and adjustment to stress: a genetic epidemiologic investigation
    • Kessler R.C., Kendler K.S., Heath A., Neale M.C., and Eaves L.J. Social support, depressed mood, and adjustment to stress: a genetic epidemiologic investigation. J. Pers. Soc. Psychol. 62 (1992) 257-272
    • (1992) J. Pers. Soc. Psychol. , vol.62 , pp. 257-272
    • Kessler, R.C.1    Kendler, K.S.2    Heath, A.3    Neale, M.C.4    Eaves, L.J.5
  • 28
    • 34247514361 scopus 로고    scopus 로고
    • Prevalence, comorbidity, and service utilization for mood disorders in the United States at the beginning of the twenty-first century
    • Kessler R.C., Merikangas K.R., and Wang P.S. Prevalence, comorbidity, and service utilization for mood disorders in the United States at the beginning of the twenty-first century. Annu. Rev. Clin. Psychol. 3 (2007) 137-158
    • (2007) Annu. Rev. Clin. Psychol. , vol.3 , pp. 137-158
    • Kessler, R.C.1    Merikangas, K.R.2    Wang, P.S.3
  • 29
    • 33748927438 scopus 로고    scopus 로고
    • MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis
    • Kim-Cohen J., Caspi A., Taylor A., Williams B., Newcombe R., Craig I.W., and Moffitt T.E. MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. Mol. Psychiatry 11 (2006) 903-913
    • (2006) Mol. Psychiatry , vol.11 , pp. 903-913
    • Kim-Cohen, J.1    Caspi, A.2    Taylor, A.3    Williams, B.4    Newcombe, R.5    Craig, I.W.6    Moffitt, T.E.7
  • 30
    • 0031423428 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder
    • Kunugi H., Hattori M., Kato T., Tatsumi M., Sakai T., Sasaki T., Hirose T., and Nanko S. Serotonin transporter gene polymorphisms: ethnic difference and possible association with bipolar affective disorder. Mol. Psychiatry 2 (1997) 457-462
    • (1997) Mol. Psychiatry , vol.2 , pp. 457-462
    • Kunugi, H.1    Hattori, M.2    Kato, T.3    Tatsumi, M.4    Sakai, T.5    Sasaki, T.6    Hirose, T.7    Nanko, S.8
  • 31
    • 12944312689 scopus 로고    scopus 로고
    • Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders
    • Lasky-Su J.A., Faraone S.V., Glatt S.J., and Tsuang M.T. Meta-analysis of the association between two polymorphisms in the serotonin transporter gene and affective disorders. Am. J. Med. Genet. B Neuropsychiatr. Genet. 133 (2005) 110-115
    • (2005) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.133 , pp. 110-115
    • Lasky-Su, J.A.1    Faraone, S.V.2    Glatt, S.J.3    Tsuang, M.T.4
  • 33
    • 0032145922 scopus 로고    scopus 로고
    • Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?
    • Lesch K.P., and Mössner R. Genetically driven variation in serotonin uptake: is there a link to affective spectrum, neurodevelopmental, and neurodegenerative disorders?. Biol. Psychiatry 44 (1998) 179-192
    • (1998) Biol. Psychiatry , vol.44 , pp. 179-192
    • Lesch, K.P.1    Mössner, R.2
  • 35
    • 33745726353 scopus 로고    scopus 로고
    • The genetics of depression: a review
    • Levinson D.F. The genetics of depression: a review. Biol. Psychiatry 60 (2006) 84-92
    • (2006) Biol. Psychiatry , vol.60 , pp. 84-92
    • Levinson, D.F.1
  • 36
    • 0034331195 scopus 로고    scopus 로고
    • Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences
    • Li Q., Wichems C., Heils A., Lesch K.P., and Murphy D.L. Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: gender and brain region differences. J. Neurosci. 20 (2000) 7888-7895
    • (2000) J. Neurosci. , vol.20 , pp. 7888-7895
    • Li, Q.1    Wichems, C.2    Heils, A.3    Lesch, K.P.4    Murphy, D.L.5
  • 37
    • 0032872035 scopus 로고    scopus 로고
    • Tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in Han Chinese
    • Liu W., Gu N., Feng G., Li S., Bai S., Zhang J., Shen T., Xue H., Breen G., St Clair D., and He L. Tentative association of the serotonin transporter with schizophrenia and unipolar depression but not with bipolar disorder in Han Chinese. Pharmacogenetics 9 (1999) 491-495
    • (1999) Pharmacogenetics , vol.9 , pp. 491-495
    • Liu, W.1    Gu, N.2    Feng, G.3    Li, S.4    Bai, S.5    Zhang, J.6    Shen, T.7    Xue, H.8    Breen, G.9    St Clair, D.10    He, L.11
  • 38
    • 4644232945 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter polymorphisms and affective disorders
    • Lotrich F.E., and Pollock B.G. Meta-analysis of serotonin transporter polymorphisms and affective disorders. Psychiatr. Genet. 14 (2004) 121-129
    • (2004) Psychiatr. Genet. , vol.14 , pp. 121-129
    • Lotrich, F.E.1    Pollock, B.G.2
  • 40
    • 0029939169 scopus 로고    scopus 로고
    • Polymorphism in serotonin transporter gene associated with susceptibility to major depression
    • Ogilvie A.D., Battersby S., Bubb V.J., Fink G., Harmar A.J., Goodwim G.M., and Smith C.A. Polymorphism in serotonin transporter gene associated with susceptibility to major depression. Lancet 347 (1996) 731-733
    • (1996) Lancet , vol.347 , pp. 731-733
    • Ogilvie, A.D.1    Battersby, S.2    Bubb, V.J.3    Fink, G.4    Harmar, A.J.5    Goodwim, G.M.6    Smith, C.A.7
  • 41
    • 27744588449 scopus 로고    scopus 로고
    • Association between 5-HTTLPR genotypes and persisting patterns of anxiety and alcohol use: results from a 10-year longitudinal study of adolescent mental health
    • Olsson C.A., Byrnes G.B., Lotfi-Miri M., Collins V., Williamson R., Patton C., and Anney R.J. Association between 5-HTTLPR genotypes and persisting patterns of anxiety and alcohol use: results from a 10-year longitudinal study of adolescent mental health. Mol. Psychiatry 10 (2005) 868-876
    • (2005) Mol. Psychiatry , vol.10 , pp. 868-876
    • Olsson, C.A.1    Byrnes, G.B.2    Lotfi-Miri, M.3    Collins, V.4    Williamson, R.5    Patton, C.6    Anney, R.J.7
  • 44
    • 0031837488 scopus 로고    scopus 로고
    • The serotonin transporter: a primary target for antidepressant drugs
    • Schloss P., and Williams D.C. The serotonin transporter: a primary target for antidepressant drugs. J. Psychopharmacol. 12 (1998) 115-121
    • (1998) J. Psychopharmacol. , vol.12 , pp. 115-121
    • Schloss, P.1    Williams, D.C.2
  • 46
    • 18944381751 scopus 로고    scopus 로고
    • SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
    • Shi Y.Y., and He L. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell. Res. 15 (2005) 97-98
    • (2005) Cell. Res. , vol.15 , pp. 97-98
    • Shi, Y.Y.1    He, L.2
  • 47
    • 32144435933 scopus 로고    scopus 로고
    • Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder
    • Surtees P.G., Wainwright N.W., Willis-Owen S.A., Luben R., Day N.E., and Flint J. Social adversity, the serotonin transporter (5-HTTLPR) polymorphism and major depressive disorder. Biol. Psychiatry 59 (2006) 224-229
    • (2006) Biol. Psychiatry , vol.59 , pp. 224-229
    • Surtees, P.G.1    Wainwright, N.W.2    Willis-Owen, S.A.3    Luben, R.4    Day, N.E.5    Flint, J.6
  • 51
    • 33747352180 scopus 로고    scopus 로고
    • Chinese social support rate scale (SSRS)
    • Wang X.D., Wang X.L., and Ma H. (Eds) [Press in Chinese]
    • Xiao S.Y. Chinese social support rate scale (SSRS). In: Wang X.D., Wang X.L., and Ma H. (Eds). Rating Scales for Mental Health. Beijing: Chin. Ment. Health J. (1999) 127-131 [Press in Chinese]
    • (1999) Rating Scales for Mental Health. Beijing: Chin. Ment. Health J. , pp. 127-131
    • Xiao, S.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.