메뉴 건너뛰기




Volumn 10, Issue 4, 2008, Pages 212-223

Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: A systematic review of virologic and biochemical evidence

Author keywords

Drug resistance; Genetic diversity; HIV 1; Non B subtypes

Indexed keywords

ABACAVIR; ATAZANAVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ENFUVIRTIDE; INDINAVIR; LAMIVUDINE; LOPINAVIR; NELFINAVIR; PROTEINASE; RITONAVIR; RNA DIRECTED DNA POLYMERASE; SAQUINAVIR; STAVUDINE; TENOFOVIR; ZIDOVUDINE;

EID: 59549100674     PISSN: 11396121     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (68)

References (56)
  • 1
    • 34648824673 scopus 로고    scopus 로고
    • HIV-1 subtype distribution in the worldwide epidemic: Pathogenetic and therapeutic implications
    • Buonaguro L, Tornesello M, Buonaguro F. HIV-1 subtype distribution in the worldwide epidemic: pathogenetic and therapeutic implications. J Virol. 2007;81:10209-19.
    • (2007) J Virol , vol.81 , pp. 10209-10219
    • Buonaguro, L.1    Tornesello, M.2    Buonaguro, F.3
  • 2
    • 33745085240 scopus 로고    scopus 로고
    • HIV-1 pol mutation frequency by subtype and treatment experience: Extension of the HIVseq program to seven non-B subtypes
    • Rhee S, Kantor R, Katzenstein D, et al. HIV-1 pol mutation frequency by subtype and treatment experience: extension of the HIVseq program to seven non-B subtypes. AIDS. 2006;20:643-51.
    • (2006) AIDS , vol.20 , pp. 643-651
    • Rhee, S.1    Kantor, R.2    Katzenstein, D.3
  • 3
    • 38449122522 scopus 로고    scopus 로고
    • HIV-1 strains identified in Brazilian blood donors: Significant prevalence of B/F1 recombinants
    • Brennan C, Brites C, Bodelle P, et al. HIV-1 strains identified in Brazilian blood donors: significant prevalence of B/F1 recombinants. AIDS Res Hum Retroviruses. 2007;23:1434-41.
    • (2007) AIDS Res Hum Retroviruses , vol.23 , pp. 1434-1441
    • Brennan, C.1    Brites, C.2    Bodelle, P.3
  • 4
    • 20244384565 scopus 로고    scopus 로고
    • French national sentinel survey of antiretroviral drug resistance in patients with HIV-1 primary infection and in antiretroviral-naive chronically infected patients in 2001-2002
    • Descamps D, Chaix M, Andre P, et al. French national sentinel survey of antiretroviral drug resistance in patients with HIV-1 primary infection and in antiretroviral-naive chronically infected patients in 2001-2002. J Acquir Immune Defic Syndr. 2005;38:545-52.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , pp. 545-552
    • Descamps, D.1    Chaix, M.2    Andre, P.3
  • 5
    • 52449125643 scopus 로고    scopus 로고
    • Increase of non-B subtypes and recombinants among newly diagnosed HIV-1 native Spaniards and immigrants in Spain
    • Holguin A, de Mulder M, Yebra G, Lopez M, Soriano V. Increase of non-B subtypes and recombinants among newly diagnosed HIV-1 native Spaniards and immigrants in Spain. Curr HIV Res. 2008;6:327-34.
    • (2008) Curr HIV Res , vol.6 , pp. 327-334
    • Holguin, A.1    de Mulder, M.2    Yebra, G.3    Lopez, M.4    Soriano, V.5
  • 6
    • 34548290957 scopus 로고    scopus 로고
    • Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil
    • Locateli D, Stoco P, de Queiroz A, et al. Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil. J Med Virol. 2007;79:1455-63.
    • (2007) J Med Virol , vol.79 , pp. 1455-1463
    • Locateli, D.1    Stoco, P.2    de Queiroz, A.3
  • 7
    • 59549094389 scopus 로고    scopus 로고
    • High proportion of non-B viral subtypes among persons with HIV-1 in Ontario
    • Toronto, Canada;
    • Njihia J, Rank C, Remis R, et al. High proportion of non-B viral subtypes among persons with HIV-1 in Ontario, 2003-2005. In: CAHR meeting. Toronto, Canada; 2007.
    • (2003) CAHR meeting , pp. 2007
    • Njihia, J.1    Rank, C.2    Remis, R.3
  • 8
    • 44449104622 scopus 로고    scopus 로고
    • Expected response to protease inhibitors of HIV-1 non-B subtype viruses according to resistance algorithms
    • Champenois K, Bocket L, Deuffic-Burban S, et al. Expected response to protease inhibitors of HIV-1 non-B subtype viruses according to resistance algorithms. AIDS. 2008;22:1087-9.
    • (2008) AIDS , vol.22 , pp. 1087-1089
    • Champenois, K.1    Bocket, L.2    Deuffic-Burban, S.3
  • 9
    • 36048933670 scopus 로고    scopus 로고
    • Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: An OPTIMA trial substudy
    • Desai S, Kyriakides T, Holodniy M, Al-Salman J, Griffith B, Kozal M. Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: an OPTIMA trial substudy. HIV Clin Trials. 2007;8:293-302.
    • (2007) HIV Clin Trials , vol.8 , pp. 293-302
    • Desai, S.1    Kyriakides, T.2    Holodniy, M.3    Al-Salman, J.4    Griffith, B.5    Kozal, M.6
  • 10
    • 44649084936 scopus 로고    scopus 로고
    • A study of seven rule-based algorithms for the interpretation of HIV-1 genotypic resistance data in Thailand
    • Poonpiriya V, Sungkanuparph S, Leechanachai P, et al. A study of seven rule-based algorithms for the interpretation of HIV-1 genotypic resistance data in Thailand. J Virol Methods. 2008;151:79-86.
    • (2008) J Virol Methods , vol.151 , pp. 79-86
    • Poonpiriya, V.1    Sungkanuparph, S.2    Leechanachai, P.3
  • 11
    • 31944440917 scopus 로고    scopus 로고
    • Discordances between interpretation algorithms for genotypic resistance to protease and reverse transcriptase inhibitors of HIV are subtype dependent
    • Snoeck J, Kantor R, Shafer RW, et al. Discordances between interpretation algorithms for genotypic resistance to protease and reverse transcriptase inhibitors of HIV are subtype dependent. Antimicrob Agents Chemother. 2006;50:694-701.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 694-701
    • Snoeck, J.1    Kantor, R.2    Shafer, R.W.3
  • 12
    • 21844469736 scopus 로고    scopus 로고
    • HIV-1 proteases from drug-naive West African patients are differentially less susceptible to protease inhibitors
    • Kinomoto M, Appiah-Opong R, Brandful J, et al. HIV-1 proteases from drug-naive West African patients are differentially less susceptible to protease inhibitors. Clin Infect Dis. 2005;41:243-51.
    • (2005) Clin Infect Dis , vol.41 , pp. 243-251
    • Kinomoto, M.1    Appiah-Opong, R.2    Brandful, J.3
  • 13
    • 33646146697 scopus 로고    scopus 로고
    • Susceptibility to antiretroviral drugs of CRF01Æ, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: Comparative genotypic and phenotypic data
    • Fleury H, Toni T, Lan N, et al. Susceptibility to antiretroviral drugs of CRF01Æ, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: comparative genotypic and phenotypic data. AIDS Res Hum Retroviruses. 2006;22:357-66.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , pp. 357-366
    • Fleury, H.1    Toni, T.2    Lan, N.3
  • 14
    • 33744548300 scopus 로고    scopus 로고
    • Natural polymorphism in protease and reverse transcriptase genes and in vitro antiretroviral drug susceptibilities of non-B HIV-1 strains from treatment-naive patients
    • Vergne L, Stuyver L, Van Houtte M, Butel C, Delaporte E, Peeters M. Natural polymorphism in protease and reverse transcriptase genes and in vitro antiretroviral drug susceptibilities of non-B HIV-1 strains from treatment-naive patients. J Clin Virol. 2006;36:43-9.
    • (2006) J Clin Virol , vol.36 , pp. 43-49
    • Vergne, L.1    Stuyver, L.2    Van Houtte, M.3    Butel, C.4    Delaporte, E.5    Peeters, M.6
  • 15
    • 0042629374 scopus 로고    scopus 로고
    • Development of phenotypic and genotypic resistance to antiretroviral therapy in the UNAIDS HIV Drug Access Initiative-Uganda
    • Weidle P, Downing R, Sozi C, et al. Development of phenotypic and genotypic resistance to antiretroviral therapy in the UNAIDS HIV Drug Access Initiative-Uganda. AIDS. 2003;17(Suppl 3):S39-48.
    • (2003) AIDS , vol.17 , Issue.SUPPL. 3
    • Weidle, P.1    Downing, R.2    Sozi, C.3
  • 16
    • 27544477733 scopus 로고    scopus 로고
    • Protease mutation M89I/V is linked to therapy failure in patients infected with the HIV-1 non-B subtypes C, F or G
    • Abecasis A, Deforche K, Snoeck J, et al. Protease mutation M89I/V is linked to therapy failure in patients infected with the HIV-1 non-B subtypes C, F or G. AIDS. 2005;19:1799-806.
    • (2005) AIDS , vol.19 , pp. 1799-1806
    • Abecasis, A.1    Deforche, K.2    Snoeck, J.3
  • 17
    • 33747778089 scopus 로고    scopus 로고
    • Investigation of baseline susceptibility to protease inhibitors in HIV-1 subtypes C, F, G and CRF02_AG
    • Abecasis A, Deforche K, Bacheler L, et al. Investigation of baseline susceptibility to protease inhibitors in HIV-1 subtypes C, F, G and CRF02_AG. Antivir Ther. 2006;11:581-9.
    • (2006) Antivir Ther , vol.11 , pp. 581-589
    • Abecasis, A.1    Deforche, K.2    Bacheler, L.3
  • 18
    • 0035933060 scopus 로고    scopus 로고
    • Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes
    • Velazquez-Campoy A, Todd M, Vega S, Freire E. Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes. Proc Natl Acad Sci USA. 2001;98:6062-7.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6062-6067
    • Velazquez-Campoy, A.1    Todd, M.2    Vega, S.3    Freire, E.4
  • 19
    • 0037047028 scopus 로고    scopus 로고
    • Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes
    • Velazquez-Campoy A, Vega S, Freire E. Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes. Biochemistry. 2002;41:8613-9.
    • (2002) Biochemistry , vol.41 , pp. 8613-8619
    • Velazquez-Campoy, A.1    Vega, S.2    Freire, E.3
  • 20
    • 0041923577 scopus 로고    scopus 로고
    • In vitro hypersusceptibility of HIV-1 subtype C protease to lopinavir
    • Gonzalez L, Brindeiro R, Tarin M, et al. In vitro hypersusceptibility of HIV-1 subtype C protease to lopinavir. Antimicrob Agents Chemother. 2003;47:2817-22.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2817-2822
    • Gonzalez, L.1    Brindeiro, R.2    Tarin, M.3
  • 21
    • 38849209120 scopus 로고    scopus 로고
    • The contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C protease
    • Coman R, Robbins A, Fernandez M, et al. The contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C protease. Biochemistry. 2008;47: 731-43.
    • (2008) Biochemistry , vol.47 , pp. 731-743
    • Coman, R.1    Robbins, A.2    Fernandez, M.3
  • 22
    • 33646383073 scopus 로고    scopus 로고
    • Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: Structural determinants for maintaining sensitivity and developing resistance to atazanavir
    • Clemente J, Coman R, Thiaville M, et al. Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry. 2006; 45:5468-77.
    • (2006) Biochemistry , vol.45 , pp. 5468-5477
    • Clemente, J.1    Coman, R.2    Thiaville, M.3
  • 23
    • 33745853539 scopus 로고    scopus 로고
    • HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture
    • Brenner B, Oliveira M, Doualla-Bell F, et al. HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture. AIDS. 2006; 20:F9-13.
    • (2006) AIDS , vol.20
    • Brenner, B.1    Oliveira, M.2    Doualla-Bell, F.3
  • 24
    • 42149158303 scopus 로고    scopus 로고
    • In vitro molecular characterization of the development of the K65R and M184V mutations in subtype C HIV-1
    • abstract 114
    • Coutsinos D, Invernizzi C, Xu H, Brenner B, Wainberg M. In vitro molecular characterization of the development of the K65R and M184V mutations in subtype C HIV-1. Antivir Ther. 2007;12(Suppl 1):S127 [abstract 114].
    • (2007) Antivir Ther , vol.12 , Issue.SUPPL. 1
    • Coutsinos, D.1    Invernizzi, C.2    Xu, H.3    Brenner, B.4    Wainberg, M.5
  • 25
    • 0037415062 scopus 로고    scopus 로고
    • A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to NNRTIs
    • Brenner B, Turner D, Oliveira M, et al. A V106M mutation in HIV-1 clade C viruses exposed to efavirenz confers cross-resistance to NNRTIs. AIDS. 2003;17:F1-5.
    • (2003) AIDS , vol.17
    • Brenner, B.1    Turner, D.2    Oliveira, M.3
  • 26
    • 43249086528 scopus 로고    scopus 로고
    • Prevalence of HIV-1 drug resistance after failure of a first HAART regimen in KwaZulu Natal, South Africa
    • Marconi V, Sunpath H, Lu Z, et al. Prevalence of HIV-1 drug resistance after failure of a first HAART regimen in KwaZulu Natal, South Africa. Clin Infect Dis. 2008;46:1589-97.
    • (2008) Clin Infect Dis , vol.46 , pp. 1589-1597
    • Marconi, V.1    Sunpath, H.2    Lu, Z.3
  • 27
    • 33845242455 scopus 로고    scopus 로고
    • High prevalence of the K65R mutation in HIV-1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens
    • Doualla-Bell F, Avalos A, Brenner B, et al. High prevalence of the K65R mutation in HIV-1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. Antimicrob Agents Chemother. 2006;50:4182-5.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 4182-4185
    • Doualla-Bell, F.1    Avalos, A.2    Brenner, B.3
  • 28
    • 59549088129 scopus 로고    scopus 로고
    • Resistance profile of patients failing first line ART in Malawi when using clinical and immunologic monitoring
    • Abstract TUAB0105, Mexico City;
    • Hosseinipour M, Oosterhout J, Weigel R, et al. Resistance profile of patients failing first line ART in Malawi when using clinical and immunologic monitoring. Abstract TUAB0105. In: 17th International AIDS Conference. Mexico City; 2008.
    • (2008) 17th International AIDS Conference
    • Hosseinipour, M.1    Oosterhout, J.2    Weigel, R.3
  • 29
    • 33845954396 scopus 로고    scopus 로고
    • K65R development among subtype C HIV-1-infected patients in tenofovir DF clinical trials
    • Miller M, Margot N, McColl D, Cheng AK. K65R development among subtype C HIV-1-infected patients in tenofovir DF clinical trials. AIDS. 2007;21:265-6.
    • (2007) AIDS , vol.21 , pp. 265-266
    • Miller, M.1    Margot, N.2    McColl, D.3    Cheng, A.K.4
  • 30
    • 0344474694 scopus 로고    scopus 로고
    • A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant HIV-1 isolates from patients treated with antiretroviral drugs
    • Hertogs K, de Bethune M, Miller V, et al. A rapid method for simultaneous detection of phenotypic resistance to inhibitors of protease and reverse transcriptase in recombinant HIV-1 isolates from patients treated with antiretroviral drugs. Antimicrob Agents Chemother. 1998;42:269-76.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 269-276
    • Hertogs, K.1    de Bethune, M.2    Miller, V.3
  • 31
    • 0036359634 scopus 로고    scopus 로고
    • A sensitive replicative system to assess HIV-1 drug resistance
    • Klimkait T. A sensitive replicative system to assess HIV-1 drug resistance. Am Clin Lab. 2002;21:20-4.
    • (2002) Am Clin Lab , vol.21 , pp. 20-24
    • Klimkait, T.1
  • 33
    • 0032750954 scopus 로고    scopus 로고
    • Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies
    • Race E, Dam E, Obry V, Paulous S, Clavel F. Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies. AIDS. 1999;13: 2061-8.
    • (1999) AIDS , vol.13 , pp. 2061-2068
    • Race, E.1    Dam, E.2    Obry, V.3    Paulous, S.4    Clavel, F.5
  • 34
    • 33750937532 scopus 로고    scopus 로고
    • Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients
    • Verheyen J, Litau E, Sing T, et al. Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients. Antivir Ther. 2006;11:879-87.
    • (2006) Antivir Ther , vol.11 , pp. 879-887
    • Verheyen, J.1    Litau, E.2    Sing, T.3
  • 35
    • 7644230388 scopus 로고    scopus 로고
    • Structural basis for co-evolution of a HIV-1 nucleocapsid-p1 cleavage site with a V82A drug-resistant mutation in viral protease
    • Prabu-Jeyabalan M, Nalivaika E, King N, Schiffer C. Structural basis for co-evolution of a HIV-1 nucleocapsid-p1 cleavage site with a V82A drug-resistant mutation in viral protease. J Virol. 2004;78:12446-54.
    • (2004) J Virol , vol.78 , pp. 12446-12454
    • Prabu-Jeyabalan, M.1    Nalivaika, E.2    King, N.3    Schiffer, C.4
  • 36
    • 0942290560 scopus 로고    scopus 로고
    • Gag non-cleavage site mutations contribute to full recovery of viral fitness in protease inhibitor-resistant HIV-1
    • Myint L, Matsuda M, Matsuda Z, et al. Gag non-cleavage site mutations contribute to full recovery of viral fitness in protease inhibitor-resistant HIV-1. Antimicrob Agents Chemother. 2004;48:444-52.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 444-452
    • Myint, L.1    Matsuda, M.2    Matsuda, Z.3
  • 38
    • 0037155193 scopus 로고    scopus 로고
    • Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors
    • Gatanaga H, Suzuki Y, Tsang H, et al. Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors. J Biol Chem. 2002;277:5952-61.
    • (2002) J Biol Chem , vol.277 , pp. 5952-5961
    • Gatanaga, H.1    Suzuki, Y.2    Tsang, H.3
  • 39
    • 0036092647 scopus 로고    scopus 로고
    • Inclusion of full length HIV-1 gag sequences in viral recombinants applied to drug susceptibility phenotyping
    • Robinson L, Gale C, Kleim J. Inclusion of full length HIV-1 gag sequences in viral recombinants applied to drug susceptibility phenotyping. J Virol Methods. 2002;104:147-60.
    • (2002) J Virol Methods , vol.104 , pp. 147-160
    • Robinson, L.1    Gale, C.2    Kleim, J.3
  • 40
    • 29444451897 scopus 로고    scopus 로고
    • Genotypic HIV-1 drug resistance in HAART-treated children in Abidjan, Cote d'Ivoire
    • Chaix M, Rouet F, Kouakoussui K, et al. Genotypic HIV-1 drug resistance in HAART-treated children in Abidjan, Cote d'Ivoire. Pediatr Infect Dis J. 2005;24:1072-6.
    • (2005) Pediatr Infect Dis J , vol.24 , pp. 1072-1076
    • Chaix, M.1    Rouet, F.2    Kouakoussui, K.3
  • 41
    • 33645372546 scopus 로고    scopus 로고
    • Phenotypic drug resistance patterns in subtype A HIV-1 clones with nonnucleoside reverse transcriptase resistance mutations
    • Eshleman S, Jones D, Galovich J, et al. Phenotypic drug resistance patterns in subtype A HIV-1 clones with nonnucleoside reverse transcriptase resistance mutations. AIDS Res Hum Retroviruses. 2006;22: 289-93.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , pp. 289-293
    • Eshleman, S.1    Jones, D.2    Galovich, J.3
  • 42
    • 39849100685 scopus 로고    scopus 로고
    • Polymorphisms in HIV-1 subtype C proteases and the potential impact on protease inhibitors
    • Bessong P. Polymorphisms in HIV-1 subtype C proteases and the potential impact on protease inhibitors. Trop Med Int Health. 2008;13: 144-51.
    • (2008) Trop Med Int Health , vol.13 , pp. 144-151
    • Bessong, P.1
  • 43
    • 32044465983 scopus 로고    scopus 로고
    • Genotypic and phenotypic analyses of HIV-1 in antiretroviral drug-naive Nigerian patients
    • Agwale S, Zeh C, Paxinos E, et al. Genotypic and phenotypic analyses of HIV-1 in antiretroviral drug-naive Nigerian patients. AIDS Res Hum Retroviruses. 2006;22:22-6.
    • (2006) AIDS Res Hum Retroviruses , vol.22 , pp. 22-26
    • Agwale, S.1    Zeh, C.2    Paxinos, E.3
  • 44
    • 0031957561 scopus 로고    scopus 로고
    • HIV-1 subtype F reverse transcriptase sequence and drug susceptibility
    • Apetrei C, Descamps D, Collin G, et al. HIV-1 subtype F reverse transcriptase sequence and drug susceptibility. J Virol. 1998;72:3534-8.
    • (1998) J Virol , vol.72 , pp. 3534-3538
    • Apetrei, C.1    Descamps, D.2    Collin, G.3
  • 45
    • 0034665229 scopus 로고    scopus 로고
    • Drug-resistant reverse transcriptase genotyping and phenotyping of B and non-B subtypes (F and A) of HIV-I found in Brazilian patients failing HAART
    • Caride E, Brindeiro R, Hertogs K, et al. Drug-resistant reverse transcriptase genotyping and phenotyping of B and non-B subtypes (F and A) of HIV-I found in Brazilian patients failing HAART. Virology. 2000;275:107-15.
    • (2000) Virology , vol.275 , pp. 107-115
    • Caride, E.1    Brindeiro, R.2    Hertogs, K.3
  • 46
    • 0034751827 scopus 로고    scopus 로고
    • Genotypic and phenotypic evidence of different drug-resistance mutation patterns between B and non-B subtype isolates of HIV-1 found in Brazilian patients failing HAART
    • Caride E, Hertogs K, Larder B, et al. Genotypic and phenotypic evidence of different drug-resistance mutation patterns between B and non-B subtype isolates of HIV-1 found in Brazilian patients failing HAART. Virus Genes. 2001;23:193-202.
    • (2001) Virus Genes , vol.23 , pp. 193-202
    • Caride, E.1    Hertogs, K.2    Larder, B.3
  • 47
    • 2542479976 scopus 로고    scopus 로고
    • Mutation D30N is not preferentially selected by HIV-1 subtype C in the development of resistance to nelfinavir
    • Grossman Z, Paxinos E, Averbuch D, et al. Mutation D30N is not preferentially selected by HIV-1 subtype C in the development of resistance to nelfinavir. Antimicrob Agents Chemother. 2004;48:2159-65.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2159-2165
    • Grossman, Z.1    Paxinos, E.2    Averbuch, D.3
  • 48
    • 4744338164 scopus 로고    scopus 로고
    • Impact of frequent natural polymorphisms at the protease gene on the in vitro susceptibility to protease inhibitors in HIV-1 non-B subtypes
    • Holguin A, Paxinos E, Hertogs K, Womac C, Soriano V. Impact of frequent natural polymorphisms at the protease gene on the in vitro susceptibility to protease inhibitors in HIV-1 non-B subtypes. J Clin Virol. 2004;31:215-20.
    • (2004) J Clin Virol , vol.31 , pp. 215-220
    • Holguin, A.1    Paxinos, E.2    Hertogs, K.3    Womac, C.4    Soriano, V.5
  • 49
    • 33746025903 scopus 로고    scopus 로고
    • Natural polymorphisms in the protease gene modulate the replicative capacity of non-B HIV-1 variants in the absence of drug pressure
    • Holguin A, Sune C, Hamy F, Soriano V, Klimkait T. Natural polymorphisms in the protease gene modulate the replicative capacity of non-B HIV-1 variants in the absence of drug pressure. J Clin Virol. 2006;36: 264-71.
    • (2006) J Clin Virol , vol.36 , pp. 264-271
    • Holguin, A.1    Sune, C.2    Hamy, F.3    Soriano, V.4    Klimkait, T.5
  • 50
    • 0034834838 scopus 로고    scopus 로고
    • Tenofovir, adefovir, and zidovudine susceptibilities of primary HIV-1 isolates with non-B subtypes or nucleoside resistance
    • Palmer S, Margot N, Gilbert H, Shaw N, Buckheit R, Miller M. Tenofovir, adefovir, and zidovudine susceptibilities of primary HIV-1 isolates with non-B subtypes or nucleoside resistance. AIDS Res Hum Retroviruses. 2001;17:1167-73.
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 1167-1173
    • Palmer, S.1    Margot, N.2    Gilbert, H.3    Shaw, N.4    Buckheit, R.5    Miller, M.6
  • 51
    • 0031883581 scopus 로고    scopus 로고
    • Drug susceptibility of subtypes A, B, C, D, and E HIV-1 primary isolates
    • Palmer S, Alaeus A, Albert J, Cox S. Drug susceptibility of subtypes A, B, C, D, and E HIV-1 primary isolates. AIDS Res Hum Retroviruses. 1998;14:157-62.
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 157-162
    • Palmer, S.1    Alaeus, A.2    Albert, J.3    Cox, S.4
  • 52
    • 2342464173 scopus 로고    scopus 로고
    • High prevalence of antiretroviral resistance in treated Ugandans infected with non-subtype B HIV-1
    • Richard N, Juntilla M, Abraha A, et al. High prevalence of antiretroviral resistance in treated Ugandans infected with non-subtype B HIV-1. AIDS Res Hum Retroviruses. 2004;20:355-64.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 355-364
    • Richard, N.1    Juntilla, M.2    Abraha, A.3
  • 53
    • 0032904487 scopus 로고    scopus 로고
    • Sequence and drug susceptibility of subtype C protease from HIV-1 seroconverters in Zimbabwe
    • Shafer R, Chuang T, Hsu P, White C, Katzenstein D. Sequence and drug susceptibility of subtype C protease from HIV-1 seroconverters in Zimbabwe. AIDS Res Hum Retroviruses. 1999;15:65-9.
    • (1999) AIDS Res Hum Retroviruses , vol.15 , pp. 65-69
    • Shafer, R.1    Chuang, T.2    Hsu, P.3    White, C.4    Katzenstein, D.5
  • 54
    • 0032995647 scopus 로고    scopus 로고
    • Genetic variation and susceptibilities to protease inhibitors among subtype B and F isolates in Brazil
    • Tanuri A, Vicente A, Otsuki K, et al. Genetic variation and susceptibilities to protease inhibitors among subtype B and F isolates in Brazil. Antimicrob Agents Chemother. 1999;43:253-8.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 253-258
    • Tanuri, A.1    Vicente, A.2    Otsuki, K.3
  • 55
    • 4344641898 scopus 로고    scopus 로고
    • Impact of nelfinavir resistance mutations on in vitro phenotype, fitness, and replication capacity of HIV-1 with subtype B and C proteases
    • Gonzalez L, Brindeiro R, Aguiar R, et al. Impact of nelfinavir resistance mutations on in vitro phenotype, fitness, and replication capacity of HIV-1 with subtype B and C proteases. Antimicrob Agents Chemother. 2004; 48:3552-5.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3552-3555
    • Gonzalez, L.1    Brindeiro, R.2    Aguiar, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.