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Volumn 41, Issue 27, 2002, Pages 8613-8619
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Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes
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Author keywords
[No Author keywords available]
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Indexed keywords
DRUG RESISTANCE;
POLYMORPHISM;
AMINO ACIDS;
DRUG THERAPY;
ENZYME INHIBITION;
GENES;
GIBBS FREE ENERGY;
PROTEINS;
THERMODYNAMICS;
VIRUSES;
MUTAGENESIS;
INDINAVIR;
KNI 764;
NELFINAVIR;
PROTEINASE INHIBITOR;
RITONAVIR;
SAQUINAVIR;
UNCLASSIFIED DRUG;
AFRICA;
AMINO ACID ANALYSIS;
ARTICLE;
BINDING AFFINITY;
BIOCHEMISTRY;
CELL VIABILITY;
DRUG RESISTANCE;
ENTHALPY;
ENTROPY;
ENZYME KINETICS;
ENZYME POLYMORPHISM;
GENE AMPLIFICATION;
HUMAN;
HUMAN IMMUNODEFICIENCY VIRUS 1;
HUMAN IMMUNODEFICIENCY VIRUS 2;
NONHUMAN;
NUCLEOTIDE SEQUENCE;
PREVALENCE;
PRIORITY JOURNAL;
PROTEINASE INHIBITION;
THERMODYNAMICS;
VIRUS MUTATION;
VIRUS TYPING;
WILD TYPE;
AFRICA;
AMIDES;
AMINO ACID SUBSTITUTION;
ANTI-HIV AGENTS;
CALORIMETRY;
DRUG RESISTANCE, VIRAL;
HIV PROTEASE;
HIV PROTEASE INHIBITORS;
HIV-1;
HUMANS;
INDINAVIR;
KINETICS;
MUTAGENESIS, SITE-DIRECTED;
NELFINAVIR;
PHENOTYPE;
POLYMORPHISM, GENETIC;
RECOMBINANT PROTEINS;
RITONAVIR;
SAQUINAVIR;
THERMODYNAMICS;
THIAZOLES;
HUMAN IMMUNODEFICIENCY VIRUS;
HUMAN IMMUNODEFICIENCY VIRUS 1;
HUMAN IMMUNODEFICIENCY VIRUS 2;
RNA VIRUSES;
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EID: 0037047028
PISSN: 00062960
EISSN: None
Source Type: Journal
DOI: 10.1021/bi020160i Document Type: Article |
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Times cited : (82)
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References (20)
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