Caspase-independent pathways of hair cell death induced by kanamycin in vivo

Cell Death and Differentiation

Volumn 13, Issue 1, 2006, Pages 20-30

  Jiang, H ^a   Sha, S H ^a   Forge, A ^b   Schacht, J ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Aminoglycosides; Apoptosis; Calpains; Cathepsin D; Necrosis

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CASPASE; CASPASE 3; CASPASE 9; CATHEPSIN D; CYSTEINE PROTEINASE; CYTOCHROME C; ENDONUCLEASE G; HYDROLASE; KANAMYCIN A; MESSENGER RNA; MU CALPAIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; CALPAIN; KANAMYCIN; MU-CALPAIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL LOSS; CELL NUCLEUS; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CORTI ORGAN; EAR PROTECTION; ENZYME ACTIVATION; ENZYME SYNTHESIS; EVOKED BRAIN STEM AUDITORY RESPONSE; HAIR CELL; HEARING LOSS; IN VIVO STUDY; INNER EAR; MALE; MOUSE; NONHUMAN; OTOTOXICITY; PRIORITY JOURNAL; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; ANIMAL; CBA MOUSE; COCHLEA; DRUG EFFECT; ELECTRON MICROSCOPY; GENETICS; METABOLISM; MITOCHONDRION; NECROSIS; PATHOLOGY;

ANIMALIA;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; CALPAIN; CASPASES; CATHEPSIN D; CELL DEATH; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HAIR CELLS; HAIR CELLS, OUTER; KANAMYCIN; MALE; MICE; MICE, INBRED CBA; MICROSCOPY, ELECTRON; MITOCHONDRIA; NECROSIS; ORGAN OF CORTI; POLY(ADP-RIBOSE) POLYMERASES; RNA, MESSENGER;

EID: 33644817763     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401706     Document Type: Article

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