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Volumn 1, Issue 1, 2008, Pages 50-56

Gemcitabine-mediated radiosensitization of human soft tissue sarcoma

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EID: 59449091435     PISSN: None     EISSN: 19365233     Source Type: Journal    
DOI: 10.1593/tlo.07121     Document Type: Article
Times cited : (15)

References (47)
  • 2
    • 0023243237 scopus 로고
    • Adult soft tissue sarcomas. A pattern of care survey of the American College of Surgeons
    • Lawrence W Jr, Donegan WL, Natarajan N, Mettlin C, Beart R, and Winchester D (1987). Adult soft tissue sarcomas. A pattern of care survey of the American College of Surgeons. Ann Surg 205, 349-359.
    • (1987) Ann Surg , vol.205 , pp. 349-359
    • Lawrence Jr, W.1    Donegan, W.L.2    Natarajan, N.3    Mettlin, C.4    Beart, R.5    Winchester, D.6
  • 3
    • 0029918660 scopus 로고    scopus 로고
    • Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma
    • Pisters PW, Harrison LB, Leung DH, Woodruff JM, Casper ES, and Brennan MF (1996). Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma. J Clin Oncol 14, 859-868.
    • (1996) J Clin Oncol , vol.14 , pp. 859-868
    • Pisters, P.W.1    Harrison, L.B.2    Leung, D.H.3    Woodruff, J.M.4    Casper, E.S.5    Brennan, M.F.6
  • 7
    • 0029866867 scopus 로고    scopus 로고
    • Retroperitoneal sarcoma: The University of Florida experience
    • Kilkenny JW III, Bland KI, and Copeland EM III (1996). Retroperitoneal sarcoma: the University of Florida experience. J Am Coll Surg 182, 329-339.
    • (1996) J Am Coll Surg , vol.182 , pp. 329-339
    • Kilkenny III, J.W.1    Bland, K.I.2    Copeland III, E.M.3
  • 8
    • 0035878627 scopus 로고    scopus 로고
    • Prognostic factors in retroperitoneal sarcoma: A multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group
    • Stoeckle E, Coindre JM, Bonvalot S, Kantor G, Terrier P, Bonichon F, and Nguyen Bui B (2001). Prognostic factors in retroperitoneal sarcoma: a multivariate analysis of a series of 165 patients of the French Cancer Center Federation Sarcoma Group. Cancer 92, 359-368.
    • (2001) Cancer , vol.92 , pp. 359-368
    • Stoeckle, E.1    Coindre, J.M.2    Bonvalot, S.3    Kantor, G.4    Terrier, P.5    Bonichon, F.6    Nguyen, B.B.7
  • 9
    • 0036804429 scopus 로고    scopus 로고
    • Long-term outcome of combined modality therapy in retroperitoneal and deep-trunk soft-tissue sarcoma: Analysis of prognostic factors
    • Youssef E, Fontanesi J, Mott M, Kraut M, Lucas D, Mekhael H, and Ben-Josef E (2002). Long-term outcome of combined modality therapy in retroperitoneal and deep-trunk soft-tissue sarcoma: analysis of prognostic factors. Int J Radiat Oncol Biol Phys 54, 514-519.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 514-519
    • Youssef, E.1    Fontanesi, J.2    Mott, M.3    Kraut, M.4    Lucas, D.5    Mekhael, H.6    Ben-Josef, E.7
  • 11
    • 0035127288 scopus 로고    scopus 로고
    • The role of apoptosis in 2′,2′-difluoro-2′-deoxycytidine (gemcitabine)-mediated radiosensitization
    • Lawrence TS, Davis MA, Hough A, and Rehemtulla A (2001). The role of apoptosis in 2′,2′-difluoro-2′-deoxycytidine (gemcitabine)-mediated radiosensitization. Clin Cancer Res 7, 314-319.
    • (2001) Clin Cancer Res , vol.7 , pp. 314-319
    • Lawrence, T.S.1    Davis, M.A.2    Hough, A.3    Rehemtulla, A.4
  • 13
    • 0028240063 scopus 로고
    • Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells
    • Shewach DS, Hahn TM, Chang E, Hertel LW, and Lawrence TS (1994). Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells. Cancer Res 54, 3218-3223.
    • (1994) Cancer Res , vol.54 , pp. 3218-3223
    • Shewach, D.S.1    Hahn, T.M.2    Chang, E.3    Hertel, L.W.4    Lawrence, T.S.5
  • 15
    • 0027180521 scopus 로고
    • 2′,2′- Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines
    • Ruiz van Haperen VW, Veerman G, Vermorken JB, and Peters GJ (1993). 2′,2′- Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines. Biochem Pharmacol 46, 762-766.
    • (1993) Biochem Pharmacol , vol.46 , pp. 762-766
    • van Haperen, V.W.R.1    Veerman, G.2    Vermorken, J.B.3    Peters, G.J.4
  • 16
    • 0034326813 scopus 로고    scopus 로고
    • The role of cell cycle progression in radiosensitization by 2′,2′-difluoro-2′-deoxycytidine
    • Ostruszka LJ and Shewach DS (2000). The role of cell cycle progression in radiosensitization by 2′,2′-difluoro-2′-deoxycytidine. Cancer Res 60, 6080-6088.
    • (2000) Cancer Res , vol.60 , pp. 6080-6088
    • Ostruszka, L.J.1    Shewach, D.S.2
  • 20
    • 2642519543 scopus 로고    scopus 로고
    • A phase I dose escalation trial of gemcitabine with radiotherapy for breast cancer in the treatment of unresectable chest wall recurrences
    • Suh WW, Schott AF, Hayman JA, Schipper MJ, Shewach DS, and Pierce LJ (2004). A phase I dose escalation trial of gemcitabine with radiotherapy for breast cancer in the treatment of unresectable chest wall recurrences. Breast J 10, 204-210.
    • (2004) Breast J , vol.10 , pp. 204-210
    • Suh, W.W.1    Schott, A.F.2    Hayman, J.A.3    Schipper, M.J.4    Shewach, D.S.5    Pierce, L.J.6
  • 21
    • 0021244486 scopus 로고
    • Mean inactivation dose: A useful concept for intercomparison of human cell survival curves
    • Fertil B, Dertinger H, Courdi A, and Malaise EP (1984). Mean inactivation dose: a useful concept for intercomparison of human cell survival curves. Radiat Res 99, 73-84.
    • (1984) Radiat Res , vol.99 , pp. 73-84
    • Fertil, B.1    Dertinger, H.2    Courdi, A.3    Malaise, E.P.4
  • 22
    • 0024398561 scopus 로고
    • Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): Critical factors that affect the amount of fluorescence and the shape of BrdUrd/ DNA histogram
    • Hoy CA, Seamer LC, and Schimke RT (1989). Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): critical factors that affect the amount of fluorescence and the shape of BrdUrd/ DNA histogram. Cytometry 10, 718-725.
    • (1989) Cytometry , vol.10 , pp. 718-725
    • Hoy, C.A.1    Seamer, L.C.2    Schimke, R.T.3
  • 23
    • 0019977912 scopus 로고
    • The treatment of softtissue sarcomas of the extremities: Prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy
    • Rosenberg SA, Tepper J, Glatstein E, Costa J, Baker A, Brennan M, DeMoss EV, Seipp C, Sindelar WF, Sugarbaker P, et al. (1982). The treatment of softtissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy. Ann Surg 196, 305-315.
    • (1982) Ann Surg , vol.196 , pp. 305-315
    • Rosenberg, S.A.1    Tepper, J.2    Glatstein, E.3    Costa, J.4    Baker, A.5    Brennan, M.6    Demoss, E.V.7    Seipp, C.8    Sindelar, W.F.9    Sugarbaker, P.10
  • 24
    • 33646567780 scopus 로고    scopus 로고
    • An open label, non-comparative phase II study of gemcitabine as salvage treatment for patients with pretreated adult type soft tissue sarcoma
    • Hartmann JT, Oechsle K, Huober J, Jakob A, Azemar M, Horger M, Kanz L, and Bokemeyer C (2006). An open label, non-comparative phase II study of gemcitabine as salvage treatment for patients with pretreated adult type soft tissue sarcoma. Invest New Drugs 24, 249-253.
    • (2006) Invest New Drugs , vol.24 , pp. 249-253
    • Hartmann, J.T.1    Oechsle, K.2    Huober, J.3    Jakob, A.4    Azemar, M.5    Horger, M.6    Kanz, L.7    Bokemeyer, C.8
  • 25
    • 0842267357 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine as second-line chemotherapy of uterine leiomyosarcoma: A Gynecologic Oncology Group (GOG) Study
    • Look KY, Sandler A, Blessing JA, Lucci JA III, and Rose PG (2004). Phase II trial of gemcitabine as second-line chemotherapy of uterine leiomyosarcoma: a Gynecologic Oncology Group (GOG) Study. Gynecol Oncol 92, 644-647.
    • (2004) Gynecol Oncol , vol.92 , pp. 644-647
    • Look, K.Y.1    Sandler, A.2    Blessing, J.A.3    Lucci III, J.A.4    Rose, P.G.5
  • 26
    • 34447572873 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: Results of sarcoma alliance for research through collaboration study 002 [corrected]
    • Maki RG, Wathen JK, Patel SR, Priebat DA, Okuno SH, Samuels B, Fanucchi M, Harmon DC, Schuetze SM, Reinke D, et al. (2007). Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 [corrected]. J Clin Oncol 25, 2755-2763.
    • (2007) J Clin Oncol , vol.25 , pp. 2755-2763
    • Maki, R.G.1    Wathen, J.K.2    Patel, S.R.3    Priebat, D.A.4    Okuno, S.H.5    Samuels, B.6    Fanucchi, M.7    Harmon, D.C.8    Schuetze, S.M.9    Reinke, D.10
  • 29
    • 0344839034 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine in patients with advanced sarcomas (E1797): A trial of the Eastern Cooperative Oncology Group
    • Okuno S, Ryan LM, Edmonson JH, Priebat DA, and Blum RH (2003). Phase II trial of gemcitabine in patients with advanced sarcomas (E1797): a trial of the Eastern Cooperative Oncology Group. Cancer 97, 1969-1973.
    • (2003) Cancer , vol.97 , pp. 1969-1973
    • Okuno, S.1    Ryan, L.M.2    Edmonson, J.H.3    Priebat, D.A.4    Blum, R.H.5
  • 30
    • 0035424877 scopus 로고    scopus 로고
    • Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation
    • Patel SR, Gandhi V, Jenkins J, Papadopolous N, Burgess MA, Plager C, Plunkett W, and Benjamin RS (2001). Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation. J Clin Oncol 19, 3483-3489.
    • (2001) J Clin Oncol , vol.19 , pp. 3483-3489
    • Patel, S.R.1    Gandhi, V.2    Jenkins, J.3    Papadopolous, N.4    Burgess, M.A.5    Plager, C.6    Plunkett, W.7    Benjamin, R.S.8
  • 33
    • 33644869706 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine as first line chemotherapy in patients with metastatic or unresectable soft tissue sarcoma
    • Von Burton G, Rankin C, Zalupski MM, Mills GM, Borden EC, and Karen A (2006). Phase II trial of gemcitabine as first line chemotherapy in patients with metastatic or unresectable soft tissue sarcoma. Am J Clin Oncol 29, 59-61.
    • (2006) Am J Clin Oncol , vol.29 , pp. 59-61
    • von Burton, G.1    Rankin, C.2    Zalupski, M.M.3    Mills, G.M.4    Borden, E.C.5    Karen, A.6
  • 34
    • 4344633285 scopus 로고    scopus 로고
    • Combined-modality therapy with gemcitabine and radiotherapy as a bladder preservation strategy: Results of a phase I trial
    • Kent E, Sandler H, Montie J, Lee C, Herman J, Esper P, Fardig J, and Smith DC (2004). Combined-modality therapy with gemcitabine and radiotherapy as a bladder preservation strategy: results of a phase I trial. J Clin Oncol 22, 2540-2545.
    • (2004) J Clin Oncol , vol.22 , pp. 2540-2545
    • Kent, E.1    Sandler, H.2    Montie, J.3    Lee, C.4    Herman, J.5    Esper, P.6    Fardig, J.7    Smith, D.C.8
  • 35
    • 0025651424 scopus 로고
    • Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells
    • Bruso CE, Shewach DS, and Lawrence TS (1990). Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells. Int J Radiat Oncol Biol Phys 19, 1411-1417.
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 1411-1417
    • Bruso, C.E.1    Shewach, D.S.2    Lawrence, T.S.3
  • 36
    • 0024371774 scopus 로고
    • Mechanism of radiosensitization by halogenated pyrimidines: Effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing
    • Iliakis G, Kurtzman S, Pantelias G, and Okayasu R (1989). Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing. Radiat Res 119, 286-304.
    • (1989) Radiat Res , vol.119 , pp. 286-304
    • Iliakis, G.1    Kurtzman, S.2    Pantelias, G.3    Okayasu, R.4
  • 37
    • 7144264394 scopus 로고    scopus 로고
    • Radiosensitization of mouse sarcoma cells by fludarabine (F-ara-A) or gemcitabine (dFdC), two nucleoside analogues, is not mediated by an increased induction or a repair inhibition of DNA double-strand breaks as measured by pulsed-field gel electrophoresis
    • Gregoire V, Beauduin M, Bruniaux M, De Coster B, Octave Prignot M, and Scalliet P (1998). Radiosensitization of mouse sarcoma cells by fludarabine (F-ara-A) or gemcitabine (dFdC), two nucleoside analogues, is not mediated by an increased induction or a repair inhibition of DNA double-strand breaks as measured by pulsed-field gel electrophoresis. Int J Radiat Biol 73, 511-520.
    • (1998) Int J Radiat Biol , vol.73 , pp. 511-520
    • Gregoire, V.1    Beauduin, M.2    Bruniaux, M.3    de Coster, B.4    Octave, P.M.5    Scalliet, P.6
  • 38
    • 0030922494 scopus 로고    scopus 로고
    • Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′- difluoro-2′-deoxycytidine (gemcitabine)
    • Lawrence TS, Chang EY, Hahn TM, and Shewach DS (1997). Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′- difluoro-2′-deoxycytidine (gemcitabine). Clin Cancer Res 3, 777-782.
    • (1997) Clin Cancer Res , vol.3 , pp. 777-782
    • Lawrence, T.S.1    Chang, E.Y.2    Hahn, T.M.3    Shewach, D.S.4
  • 39
    • 0034100255 scopus 로고    scopus 로고
    • The role of p53 in gemcitabine- mediated cytotoxicity and radiosensitization
    • Chen M, Hough AM, and Lawrence TS (2000). The role of p53 in gemcitabine- mediated cytotoxicity and radiosensitization. Cancer Chemother Pharmacol 45, 369-374.
    • (2000) Cancer Chemother Pharmacol , vol.45 , pp. 369-374
    • Chen, M.1    Hough, A.M.2    Lawrence, T.S.3
  • 41
    • 0025737572 scopus 로고    scopus 로고
    • Jarvi E, and Resvick R (1991). 2′-Deoxy-2′-methylenecytidine and 2′-deoxy- 2′,2′-difluorocytidine 5′-diphosphates: Potent mechanism-based inhibitors of ribonucleotide reductase
    • Baker CH, Banzon J, Bollinger JM, Stubbe J, Samano V, Robins MJ, Lippert B, Jarvi E, and Resvick R (1991). 2′-Deoxy-2′-methylenecytidine and 2′-deoxy- 2′,2′-difluorocytidine 5′-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase. J Med Chem 34, 1879-1884.
    • J Med Chem , vol.34 , pp. 1879-1884
    • Baker, C.H.1    Banzon, J.2    Bollinger, J.M.3    Stubbe, J.4    Samano, V.5    Robins, M.J.6    Lippert, B.7
  • 42
    • 34250721675 scopus 로고    scopus 로고
    • Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: A new paradigm for antimetabolite radiosensitizers
    • Flanagan SA, Robinson BW, Krokosky CM, and Shewach DS (2007). Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: a new paradigm for antimetabolite radiosensitizers. Mol Cancer Ther 6, 1858-1868.
    • (2007) Mol Cancer Ther , vol.6 , pp. 1858-1868
    • Flanagan, S.A.1    Robinson, B.W.2    Krokosky, C.M.3    Shewach, D.S.4
  • 43
    • 0142219871 scopus 로고    scopus 로고
    • Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells
    • Robinson BW, Im MM, Ljungman M, Praz F, and Shewach DS (2003). Enhanced radiosensitization with gemcitabine in mismatch repair-deficient HCT116 cells. Cancer Res 63, 6935-6941.
    • (2003) Cancer Res , vol.63 , pp. 6935-6941
    • Robinson, B.W.1    Im, M.M.2    Ljungman, M.3    Praz, F.4    Shewach, D.S.5
  • 44
    • 80052649091 scopus 로고    scopus 로고
    • Phase I trial using toxicity severity weights for dose finding of gemcitabine combined with radiation therapy and subsequent surgery for patients with extremity and trunk soft tissue sarcomas
    • Pisters PW, Ballo MT, Bekele PF, Feig P, Lin JN, Cormier RS, and Benjamin SR (2004). Phase I trial using toxicity severity weights for dose finding of gemcitabine combined with radiation therapy and subsequent surgery for patients with extremity and trunk soft tissue sarcomas. J Clin Oncol 22(14S), 9008.
    • (2004) J Clin Oncol , vol.22 , Issue.14 SUPPL. , pp. 9008
    • Pisters, P.W.1    Ballo, M.T.2    Bekele, P.F.3    Feig, P.4    Lin, J.N.5    Cormier, R.S.6    Benjamin, S.R.7


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