Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity

Journal of Clinical Oncology

Volumn 16, Issue 1, 1998, Pages 197-203

  Yang, James C ^a   Chang, Alfred E ^a   Baker, Alan R ^a   Sindelar, William F ^a   Danforth, David N ^a   Topalian, Suzanne L ^a   DeLaney, Thomas ^a   Glatstein, Eli ^a   Steinberg, Seth M ^a   Merino, Maria J ^a   Rosenberg, Steven A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN;

ARTICLE; BEAM THERAPY; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DAILY LIFE ACTIVITY; EDEMA; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; JOINT CHARACTERISTICS AND FUNCTIONS; LIMB SALVAGE; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; PRIORITY JOURNAL; QUALITY OF LIFE; RANDOMIZED CONTROLLED TRIAL; SOFT TISSUE SARCOMA;

EID: 0031962230     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.1.197     Document Type: Article

References (32)

1. Suit HD, Russell WO, Martin RG: Sarcoma of soft tissue: Clinical and histopathologic parameters and response to treatment. Cancer 35:1478-1483, 1975
2. Lindberg RD, Martin RG, Romsdahl MM, et al: Conservative surgery and postoperative radiotherapy in 300 adults with soft-tissue sarcomas. Cancer 47:2391-2397, 1981
3. McNeer GP, Cantin J, Chu F, et al: Effectiveness of radiation therapy in the management of sarcoma of the soft somatic tissues. Cancer 22:391-397, 1968
4. Cantin J, McNeer GP, Chu FC, et al: The problem of local recurrence after treatment of soft tissue sarcoma. Ann Surg 168:47-53, 1968
5. Gerner RE, Moore GE, Pickren JW: Soft tissue sarcomas. Ann Surg 181:803-808, 1975
6. Rosenberg SA, Tepper J, Glatstein E, et al: The treatment of soft-tissue sarcomas of the extremities. Ann Surg 196:305-315, 1982
7. Lawrence W Jr, Donegan WL, Nachimuth N, et al: Adult soft tissue sarcomas: A pattern of care survey of the American College of Surgeons. Ann Surg 205:349-359, 1987
8. Stinson SF, DeLaney TF, Greenberg J, et al: Acute and long-term effects on limb function of combined modality limb sparing therapy for extremity soft tissue sarcoma. Int J Radiat Oncol Biol Phys 21:1493-1499, 1992
9. Stotter AT, A'Hern RP, Fisher C: The influence of local recurrence of extremity soft tissue sarcoma on metastasis and survival. Cancer 65:1119-1129, 1990
10. Collins CF, Friedrich C, Godbold J, et al: Prognostic factors for local recurrence and survival in patients with localized extremity soft-tissue sarcoma. Semin Surg Oncol 4:30-37, 1988
11. Rooser B, Gustafson P, Rydholm A: Is there no influence of local control on the rate of metastases in high-grade soft tissue sarcoma? Cancer 65:1727-1729, 1990
12. Gustafson P, Rooser B, Rydholm A: Is local recurrence of minor importance for metastases in soft tissue sarcoma? Cancer 67:2083-2086, 1991
13. Brennan MF, Hilaris B, Shiu MH, et al: Local recurrence in adult soft-tissue sarcoma. Arch Surg 122:1289-1293, 1987
14. Pisters PWT, Harrison LB, Leung DHY, et al: Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma. J Clin Oncol 14:859-868, 1996
15. Alvegard TA, Sigurdsson H, Mouridsen H, et al: Adjuvant chemotherapy with doxorubicin for high-grade soft tissue sarcoma: A randomized trial of the Scandinavian Sarcoma Group. J Clin Oncol 7:1504-1513, 1989
16. Bramwell V, Rouesse J, Steward W, et al: Adjuvant CYVADIC chemotherapy for adult soft tissue sarcoma - reduced local recurrence but no improvement in survival: A study of the EORTC Soft Tissue and Bone Sarcoma Group. J Clin Oncol 12:1137-1149, 1994
17. Ravaud A, Bui NB, Coindre JM, et al: Adjuvant chemotherapy with CYVADIC in high risk soft tissue sarcoma: A randomized prospective trial, in Salmon SE (ed): Adjuvant Therapy of Cancer 1990, vol 6, Philadelphia, PA, Saunders, pp 556-566
18. Rosenberg SA, Tepper J, Glatstein E, et al: Prospective randomized evaluation of adjuvant chemotherapy in adults with soft tissue sarcomas of the extremities. Cancer 52:424-434, 1983
19. Chang AE, Kinsella T, Glatstein E, et al: Adjuvant chemotherapy for patients with high-grade soft-tissue sarcomas of the extremity. J Clin Oncol 6:1491-1500, 1988
20. Costa J, Wesley RA, Glatstein E, et al: The grading of soft tissue sarcomas: Results of a clinicohistopathologic correlation in a series of 163 cases. Cancer 53:530-541, 1984
21. Chang AE, Steinberg SM, Culnane M, et al: Functional and psychosocial effects of multimodality limb-sparing therapy in patients with soft tissue sarcomas. J Clin Oncol 7:1217-1228, 1989
22. Scranton J, Fogel ML, Erdman WR II: Evaluation of functional levels of patients during and following rehabilitation. Arch Phys Med Rehabil 51:1-21, 1970
23. Schipper H, Clinch J, McMurray A, et al: Measuring the quality of life of cancer patients: The Functional Living Index - Cancer: Development and validation. J Clin Oncol 2:472-483, 1984
24. Mantel N: Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 50:163-170, 1966
25. Kaplan E, Meier P: Non-parametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
26. Mehta CR, Patel NR: A Network algorithm for performing Fisher's exact test in r × c contingency tables. J Am Stat Assoc 78:427-434, 1983
27. Fisher B, Bauer M, Margolese R: Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med 312:666-673, 1985
28. Gastrointestinal Tumor Study Group: Prolongation of the disease-free interval in surgically treated rectal carcinoma. N Engl J Med 312:1467-1472, 1985
29. Pisters PW, Harrison LB, Woodruff JM, et al: A prospective randomized trial of adjuvant brachytherapy in the management of low-grade soft tissue sarcomas of the extremity and superficial trunk. J Clin Oncol 12:1150-1155, 1994
30. Harrison LB, Franzese F, Gaynor JJ, et al: Long-term results of a prospective randomized trial of adjuvant brachytherapy in the management of completely resected soft tissue sarcomas of the extremity and superficial trunk. Int J Radiat Oncol Biol Phys 27:259-265, 1993
31. Markhede G, Angervall L, Stener B: A multivariate analysis of the prognosis after surgical treatment of malignant soft-tissue tumors. Cancer 49:1721-1733, 1982
32. Collin CF, Friedrich C, Godbold J, et al: Prognostic factors for local recurrence and survival in patients with localized extremity soft-tissue sarcoma. Semin Surg Oncol 4:30-37, 1988