-
1
-
-
0025737572
-
2′-Deoxy-2′-methylenecytidine and 2′-deoxy-2′,2′-difluorocytidine 5′-diphosphates: Potent mechanism-based inhibitors of ribonucleotide reductase
-
1. Baker CH, Banzon J, Bollinger JM, et al (1991) 2′-Deoxy-2′-methylenecytidine and 2′-deoxy-2′,2′-difluorocytidine 5′-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase. J Med Chem 34: 1879-1884
-
(1991)
J Med Chem
, vol.34
, pp. 1879-1884
-
-
Baker, C.H.1
Banzon, J.2
Bollinger, J.M.3
-
2
-
-
0030630531
-
Role of p53 in apoptosis
-
2. Canman C, Kastan M (1997) Role of p53 in apoptosis. Adv Pharmacol 41: 429-460
-
(1997)
Adv Pharmacol
, vol.41
, pp. 429-460
-
-
Canman, C.1
Kastan, M.2
-
3
-
-
0027993581
-
Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells
-
3. Chen HH, Zhang J, Ling CC (1994) Transfected c-myc and c-Ha-ras modulate radiation-induced apoptosis in rat embryo cells. Radiat Res 139: 307-315
-
(1994)
Radiat Res
, vol.139
, pp. 307-315
-
-
Chen, H.H.1
Zhang, J.2
Ling, C.C.3
-
4
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
4. Fan S, Smith ML, Rivet DJ, et al (1995) Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 55: 1649-1654
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
-
5
-
-
0021244486
-
Mean inactivation dose: A useful concept for intercomparison of human cell survival curves
-
5. Fertil B, Dertinger H, Courdi A, et al (1984) Mean inactivation dose: a useful concept for intercomparison of human cell survival curves. Radiat Res 99: 73-84
-
(1984)
Radiat Res
, vol.99
, pp. 73-84
-
-
Fertil, B.1
Dertinger, H.2
Courdi, A.3
-
6
-
-
0030632192
-
Pathways of p53-dependent apoptosis
-
6. Grasso L, Mercer W (1997) Pathways of p53-dependent apoptosis. Vitamins Hormones 53: 139-173
-
(1997)
Vitamins Hormones
, vol.53
, pp. 139-173
-
-
Grasso, L.1
Mercer, W.2
-
7
-
-
0029868112
-
The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death promoting bax protein
-
7. Han J, Sabbatini P, Perez D, et al (1996) The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death promoting bax protein. Genes Dev 10: 461-477
-
(1996)
Genes Dev
, vol.10
, pp. 461-477
-
-
Han, J.1
Sabbatini, P.2
Perez, D.3
-
8
-
-
0028568315
-
Cell cycle control and cancer
-
8. Hartwell LH, Kastan MB (1994) Cell cycle control and cancer. Science 266: 1821-1828
-
(1994)
Science
, vol.266
, pp. 1821-1828
-
-
Hartwell, L.H.1
Kastan, M.B.2
-
9
-
-
0024398561
-
Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): Critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA istogram
-
9. Hoy CA, Seamer LC, Schimke RT (1989) Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): critical factors that affect the amount of fluorescence and the shape of BrdUrd/DNA histogram. Cytometry 10: 718-725
-
(1989)
Cytometry
, vol.10
, pp. 718-725
-
-
Hoy, C.A.1
Seamer, L.C.2
Schimke, R.T.3
-
10
-
-
0029060757
-
Fludarabine-and gemcitabine-induced apoptosis: Incorporation of analogs into DNA is a critical event
-
10. Huang P, Plunkett W (1995) Fludarabine-and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother Pharmacol 36: 181-188
-
(1995)
Cancer Chemother Pharmacol
, vol.36
, pp. 181-188
-
-
Huang, P.1
Plunkett, W.2
-
12
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
12. Kastan MB, Onyekwere O, Sidransky D, Volgestein B, Craig RW (1991) Participation of p53 protein in the cellular response to DNA damage. Cancer Res 51: 6304-6311
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Volgestein, B.4
Craig, R.W.5
-
13
-
-
0027266971
-
Human papillomavirus 16 E6 expression disrupts the p53-mediated response to DNA damage
-
13. Kessis TD, Siebos RJ, Nelson WG, et al (1993) Human papillomavirus 16 E6 expression disrupts the p53-mediated response to DNA damage. Proc Natl Acad Sci USA 90: 3988-3992
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3988-3992
-
-
Kessis, T.D.1
Siebos, R.J.2
Nelson, W.G.3
-
14
-
-
0026656853
-
Wild type p53 is a cell cycle check point determinant following irradiation
-
14. Kuerbitz SJ, Plunkett BS, Walsh WV, et al (1992) Wild type p53 is a cell cycle check point determinant following irradiation. Proc Natl Acad Sci USA 89: 7491-7495
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
-
15
-
-
0027109075
-
P53, guardian of the genome
-
15. Lane D (1992) P53, guardian of the genome. Nature 358: 15-16
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.1
-
16
-
-
0031804603
-
Radiosensitizing potential of gemcitabine 2′,2′-difluoro-2′-deoxycytidine within the cell cycle in vitro
-
16. Latz D, Fleckenstein K, Eble M, et al (1998) Radiosensitizing potential of gemcitabine (2′,2′-difluoro-2′-deoxycytidine within the cell cycle in vitro. Int J Radiat Oncol Biol Phys 41: 875-882
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.41
, pp. 875-882
-
-
Latz, D.1
Fleckenstein, K.2
Eble, M.3
-
17
-
-
0030005273
-
Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine
-
17. Lawrence TS, Chang EY, Hahn TM, et al (1996) Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine. Int J Radiat Oncol Biol Phys 34: 867-872
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.34
, pp. 867-872
-
-
Lawrence, T.S.1
Chang, E.Y.2
Hahn, T.M.3
-
18
-
-
0030922494
-
Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′-difluoro-2′-deoxycytidine (Gemcitabine)
-
18. Lawrence TS, Chang EY, Hahn TM, et al (1997) Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′-difluoro-2′-deoxycytidine (Gemcitabine). Clin Cancer Res 3: 777-782
-
(1997)
Clin Cancer Res
, vol.3
, pp. 777-782
-
-
Lawrence, T.S.1
Chang, E.Y.2
Hahn, T.M.3
-
22
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anti-cancer agents
-
22. Lowe SW, Ruley HE, Jacks T, et al (1993) p53-dependent apoptosis modulates the cytotoxicity of anti-cancer agents. Cell 74: 947-967
-
(1993)
Cell
, vol.74
, pp. 947-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
-
23
-
-
0030938089
-
Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
-
23. McCurrach M, Connor T, Knudson C, et al (1997) Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc Natl Acad Sci USA 94: 2345-2349
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2345-2349
-
-
McCurrach, M.1
Connor, T.2
Knudson, C.3
-
25
-
-
0000046403
-
A phase I study of gemcitabine in combination with radiation therapy in patients with localized unresectable pancreatic cancer
-
25. McGinn C, Smith D, Szarka C, et al (1998) A phase I study of gemcitabine in combination with radiation therapy in patients with localized unresectable pancreatic cancer. Proc Am Soc Cancer Oncol 17: 264a
-
(1998)
Proc Am Soc Cancer Oncol
, vol.17
-
-
McGinn, C.1
Smith, D.2
Szarka, C.3
-
26
-
-
0027931008
-
Cell cycle arrests and radiosensitivity of human tumor cell lines: Dependence on wild-type p53 for radiosensitivity
-
26. McIlwrath AJ, Vasey PA, Ross GM, et al (1994) Cell cycle arrests and radiosensitivity of human tumor cell lines: dependence on wild-type p53 for radiosensitivity. Cancer Res 54: 3718-3722
-
(1994)
Cancer Res
, vol.54
, pp. 3718-3722
-
-
McIlwrath, A.J.1
Vasey, P.A.2
Ross, G.M.3
-
27
-
-
0028335717
-
Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
-
27. Miyashita T, Krajewski S, Krajewski M, et al (1994) Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogenetics 9: 1799-1805
-
(1994)
Oncogenetics
, vol.9
, pp. 1799-1805
-
-
Miyashita, T.1
Krajewski, S.2
Krajewski, M.3
-
28
-
-
0030910037
-
p53 and ATM: Cell cycle, cell death, and cancer
-
28. Morgan SE, Kastan MB (1997) p53 and ATM: cell cycle, cell death, and cancer. Adv Cancer Res 71: 1-25
-
(1997)
Adv Cancer Res
, vol.71
, pp. 1-25
-
-
Morgan, S.E.1
Kastan, M.B.2
-
29
-
-
0031799135
-
The effect of activation of wild type p53 function on fluoropyrimidine-mediated radiosensitization
-
29. Naida JD, Davis MA, Lawrence TS (1998) The effect of activation of wild type p53 function on fluoropyrimidine-mediated radiosensitization. Int J Radiat Oncol Biol Phys 41: 675-680
-
(1998)
Int J Radiat Oncol Biol Phys
, vol.41
, pp. 675-680
-
-
Naida, J.D.1
Davis, M.A.2
Lawrence, T.S.3
-
30
-
-
0030612166
-
Mammalian G1 and G2 phase checkpoints
-
30. O'Connor PM (1997) Mammalian G1 and G2 phase checkpoints. Cancer Surv 29: 151-182
-
(1997)
Cancer Surv
, vol.29
, pp. 151-182
-
-
O'Connor, P.M.1
-
31
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
31. Oltvai Z, Milliman C, Korsmeyer S (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.1
Milliman, C.2
Korsmeyer, S.3
-
32
-
-
0028799108
-
Gemcitabine: Metabolism, mechanisms of action, and self-potentiation
-
32. Plunkett W, Huang P, Xu Y-Z, et al (1995) Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin Oncol 22 [Suppl 11]: S3-S10
-
(1995)
Semin Oncol
, vol.22
, Issue.SUPPL. 11
-
-
Plunkett, W.1
Huang, P.2
Xu, Y.-Z.3
-
33
-
-
0028062981
-
Molecular effects of 2′,2′-difluorodeoxycytidine on DNA replication in intact HL-60 cells
-
33. Ross DD, Cuddy DP (1994) Molecular effects of 2′,2′-difluorodeoxycytidine on DNA replication in intact HL-60 cells. Biochem Pharmacol 48: 1619-1630
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1619-1630
-
-
Ross, D.D.1
Cuddy, D.P.2
-
34
-
-
0029097470
-
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax
-
34. Sedlak T, Oltvai Z, Yang E, et al (1995) Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 92: 7834-7838
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7834-7838
-
-
Sedlak, T.1
Oltvai, Z.2
Yang, E.3
-
35
-
-
0028238213
-
Immediate early up-regulation of bax expression by p53 but not TGF beta 1: A paradigm for distinct apoptotic pathways
-
35. Selvakumaran M, Lin H, Miyashita T, et al (1994) Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways. Oncogene 9: 1791-1798
-
(1994)
Oncogene
, vol.9
, pp. 1791-1798
-
-
Selvakumaran, M.1
Lin, H.2
Miyashita, T.3
-
36
-
-
0029840251
-
p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell
-
36. Servomaa K, Kiuru A, Grenman R, et al (1996) p53 mutations associated with increased sensitivity to ionizing radiation in human head and neck cancer cell. Cell Prolif 29: 1649-1654
-
(1996)
Cell Prolif
, vol.29
, pp. 1649-1654
-
-
Servomaa, K.1
Kiuru, A.2
Grenman, R.3
-
37
-
-
0028839329
-
Radiosensitization of human tumor cells by gemcitabine in vitro
-
37. Shewach D, Lawrence T (1995) Radiosensitization of human tumor cells by gemcitabine in vitro. Semin Oncol [Suppl] 22: 68-71
-
(1995)
Semin Oncol
, vol.22
, Issue.SUPPL.
, pp. 68-71
-
-
Shewach, D.1
Lawrence, T.2
-
38
-
-
0028240063
-
Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells
-
38. Shewach DS, Hahn TM, Chang E, et al (1994) Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells. Cancer Res 54: 3218-3223
-
(1994)
Cancer Res
, vol.54
, pp. 3218-3223
-
-
Shewach, D.S.1
Hahn, T.M.2
Chang, E.3
-
39
-
-
0013635636
-
Sensitivity to mitotic delay and stage in the cycle
-
39. Sinclair WK (1972) Sensitivity to mitotic delay and stage in the cycle. Curr Top Radiat Res 7: 323-327
-
(1972)
Curr Top Radiat Res
, vol.7
, pp. 323-327
-
-
Sinclair, W.K.1
-
40
-
-
0028296270
-
Influence of cell cycle phase on radiation-induced cytotoxicity and DNA damage in human colon cancer (HT29) and Chinese hamster ovary cells
-
40. Tang H-Y, Davis MA, Strickfaden SM, et al (1994) Influence of cell cycle phase on radiation-induced cytotoxicity and DNA damage in human colon cancer (HT29) and Chinese hamster ovary cells. Radiat Res 138: S109-S112
-
(1994)
Radiat Res
, vol.138
-
-
Tang, H.-Y.1
Davis, M.A.2
Strickfaden, S.M.3
-
41
-
-
0023741259
-
Growth phase related variation in the radiation sensitivity of human colon adenocarcinoma cells
-
41. West CML, Keng PC, Sutherland RM (1988) Growth phase related variation in the radiation sensitivity of human colon adenocarcinoma cells. Int J Radiat Oncol Biol Phys 14: 1213-1219
-
(1988)
Int J Radiat Oncol Biol Phys
, vol.14
, pp. 1213-1219
-
-
West, C.M.L.1
Keng, P.C.2
Sutherland, R.M.3
-
42
-
-
0013654573
-
Masked radiosensitization by gemcitabine
-
42. Yang S, Zhang X (1998) Masked radiosensitization by gemcitabine. Proc Radiat Res Soc 46: 181
-
(1998)
Proc Radiat Res Soc
, vol.46
, pp. 181
-
-
Yang, S.1
Zhang, X.2
|