-
2
-
-
8944261362
-
A Phase II trial of gemcitabine in patients with 5-FU-refractory pancreas cancer
-
(1996)
Ann. Oncol.
, vol.7
, pp. 347-353
-
-
Rothenberg, M.L.1
Moore, M.J.2
Cripps, M.C.3
Andersen, J.S.4
Portenoy, R.K.5
Burris III, H.A.6
Green, M.R.7
Tarassoff, P.G.8
Brown, T.D.9
Casper, E.S.10
Storniolo, A.M.11
Von Hoff, D.D.12
-
4
-
-
0031025090
-
Maximum-tolerated dose defined for single-agent gemcitabine: A Phase I dose-escalation study in chemotherapy-naive patients with advanced non-small-cell lung cancer
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 310-316
-
-
Fossella, F.V.1
Lippman, S.C.2
Shin, D.M.3
Tarassoff, P.4
Calayag-Jung, M.5
Perez-Soler, R.6
Lee, J.S.7
Murphy, W.K.8
Glisson, B.9
Rivera, E.10
Hong, W.K.11
-
6
-
-
0032188825
-
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines
-
(1998)
Cancer Res.
, vol.58
, pp. 4349-4357
-
-
Mackey, J.R.1
Mani, R.S.2
Selner, M.3
Mowles, D.4
Young, J.D.5
Belt, J.A.6
Crawford, C.R.7
Cass, C.E.8
-
13
-
-
0025049372
-
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 567-572
-
-
Heinemann, V.1
Xu, Y.-Z.2
Chubb, S.3
Sen, A.4
Hertel, L.W.5
Grindey, G.B.6
Plunkett, W.7
-
14
-
-
0025737572
-
2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine 5'-diphosphates: Potent mechanism-based inhibitors of ribonucleotide reductase
-
(1991)
J. Med. Chem.
, vol.34
, pp. 1879-1884
-
-
Baker, C.H.1
Banzon, J.2
Bollinger, J.M.3
Stubbe, J.4
Samano, V.5
Robins, M.J.6
Lippert, B.7
Jarvi, E.8
Resvick, R.9
-
15
-
-
0026571795
-
Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: A mechanism of self-potentiation
-
(1992)
Cancer Res.
, vol.52
, pp. 533-539
-
-
Heinemann, V.1
Xu, Y.-Z.2
Chubb, S.3
Sen, A.4
Hertel, L.W.5
Grindey, G.B.6
Plunkett, W.7
-
18
-
-
0014253355
-
The combined effect of hydroxyurea and X-rays on Chinese hamster cells in vitro
-
(1968)
Cancer Res.
, vol.28
, pp. 198-206
-
-
Sinclair, W.K.1
-
19
-
-
0017728872
-
The effects of incorporation of 5-halogenated deoxyuridines into the DNA of eukaryotic cells
-
(1978)
Pharmacol. Rev.
, vol.29
, pp. 249-272
-
-
Goz, B.1
-
25
-
-
0032948219
-
Enhancement of tumor radioresponse in vivo by gemcitabine
-
(1999)
Cancer Res.
, vol.59
, pp. 104-114
-
-
Milas, L.1
Fujii, T.2
Hunter, N.3
Elshaikh, M.4
Mason, K.A.5
Plunkett, W.6
Ang, K.K.7
Hittelman, W.8
-
26
-
-
0032815755
-
Maximizing therapeutic gain with gemcitabine and fractionated radiation
-
(1999)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.44
, pp. 1125-1135
-
-
Mason, K.A.1
Milas, L.2
Hunter, N.R.3
Elshaikh, M.4
Buchmiller, L.5
Kishi, K.6
Hittelman, W.N.7
Ang, K.K.8
-
27
-
-
0003222655
-
Phase I trial of radiation (RT) concurrent with low-dose gemcitabine (GEM) for head and neck cancer. High mucosal and pharyngeal toxicity
-
(1997)
Proc. Am. Soc. Clin. Oncol.
, vol.16
-
-
Eisbruch, A.1
Shewach, D.S.2
Urba, S.3
Wolf, G.T.4
Bradford, C.R.5
Marentette, L.J.6
Terell, J.E.7
Hogikyan, N.D.8
Esclamade, R.M.9
Lawrence, T.S.10
-
28
-
-
0033022613
-
Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2208-2212
-
-
Blackstock, A.W.1
Bernard, S.A.2
Richards, F.3
Eagle, K.S.4
Case, L.D.5
Poole, M.E.6
Savage, P.D.7
Tepper, J.E.8
-
29
-
-
0007155256
-
Concurrent infusional gemcitabine and radiation in the treatment of advanced unresectable GI malignancy
-
(1999)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.45
, Issue.SUPPL.
, pp. 255
-
-
Mohiuddin, M.1
Kurdrimoti, M.2
Regine, P.3
McGrath, P.4
Hanna, N.5
Meeker, T.6
John, W.7
-
31
-
-
0024405228
-
Modification of radiotherapy by radiosensitizers and cancer chemotherapy agents. I. Radiosensitizers
-
(1989)
Semin. Oncol.
, vol.16
, pp. 169-175
-
-
Coleman, C.N.1
-
33
-
-
0032005473
-
Influence of bromodeoxyuridine radiosensitization on malignant glioma patient survival: A retrospective comparison of survival data from the northern California oncology group (NCOG) and radiation therapy oncology group trials (RTOG) for glioblastoma multiforme and anaplastic astrocytoma
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.40
, pp. 653-659
-
-
Prados, M.D.1
Scott, C.B.2
Rotman, M.3
Rubin, P.4
Murray, K.5
Sause, W.6
Asbell, S.7
Comis, R.8
Curran, W.9
Nelson, J.10
Davis, R.L.11
Levin, V.A.12
Lamborn, K.13
Phillips, T.L.14
-
35
-
-
0027965149
-
Bromodeoxyuridine-mediated radiosensitization in human glioma: The effect of concentration, duration, and fluoropyrimidine modulation
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.30
, pp. 601-607
-
-
McLaughlin, P.W.1
Lawrence, T.S.2
Seabury, H.3
Nguyen, N.4
Stetson, P.L.5
Greenberg, H.6
Mancini, W.R.7
-
36
-
-
0030865104
-
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
-
(1997)
Cancer Res.
, vol.57
, pp. 4285-4300
-
-
O'Connor, P.M.1
Jackman, J.2
Bae, I.3
Myers, T.G.4
Fan, S.5
Mutoh, M.6
Scudiero, D.A.7
Monks, A.8
Sausville, E.A.9
Weinstein, J.N.10
Friend, S.11
Fornace A.J., Jr.12
Kohn, K.W.13
-
37
-
-
0028117269
-
Analysis of the p53 gene and its expression in human glioblastoma cells
-
(1994)
Cancer Res.
, vol.54
, pp. 649-652
-
-
Van Meir, E.G.1
Kikuchi, T.2
Tada, M.3
Li, H.4
Diserens, A.-C.5
Wojcik, B.E.6
Huang, H.-J.S.7
Friedmann, T.8
Tribolet, N.9
Cavenee, W.K.10
-
38
-
-
0030020689
-
Adenovirus-mediated transfer of the p53 gene produces rapid and generalized death of human glioma cells via apoptosis
-
(1996)
Cancer Res.
, vol.56
, pp. 694-699
-
-
Gomez-Manzano, C.1
Fueyo, J.2
Kyritsis, A.P.3
Steck, P.A.4
Roth, J.A.5
McDonnell, T.J.6
Steck, K.D.7
Levin, V.A.8
Yung, W.K.A.9
-
41
-
-
0030990910
-
Reappraisal of p53 mutations in human malignant astrocytic neoplasms by p53 functional assay: Comparison with conventional structural analyses
-
(1997)
Mol. Carcinog.
, vol.18
, pp. 171-176
-
-
Tada, M.1
Iggo, R.D.2
Waridel, F.3
Nozaki, M.4
Matsumoto, R.5
Sawamura, Y.6
Shinohe, Y.7
Ikeda, J.8
Abe, H.9
-
42
-
-
0030941458
-
p53, The cellular gatekeeper for growth and division
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
45
-
-
0026801917
-
Quantitation of deoxyribonucleoside 5'-triphosphates by a sequential boronate and anion-exchange high pressure liquid chromatography procedure
-
(1992)
Anal. Biochem.
, vol.206
, pp. 178-182
-
-
Shewach, D.S.1
-
46
-
-
0024398561
-
Thermal denaturation of DNA for immunochemical staining of incorporated bromodeoxyuridine (BrdUrd): Critical factors that affect the amount of fluorescence and the shape of the BrdUrd/DNA histogram
-
(1989)
Cytometry
, vol.10
, pp. 718-725
-
-
Hoy, C.A.1
Seamer, L.C.2
Schimke, R.T.3
-
48
-
-
0032475878
-
Signaling to p53: Breaking the mdm2-p53 circuit
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
55
-
-
7144264394
-
Radiosensitization of mouse sarcoma cells by fludarabine (F-ara-A) or gemcitabine (dFdC), two nucleoside analogues, is not mediated by an increased induction or a repair inhibition of DNA double-strand breaks as measured by pulsed-field gel electrophoresis
-
(1998)
Int. J. Radiat. Biol.
, vol.73
, pp. 511-520
-
-
Gregoire, V.1
Beauduin, M.2
Bruniaux, M.3
DeCoster, B.4
Octave Prignot, M.5
Scalliet, P.6
-
57
-
-
0029662191
-
p53-dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma
-
(1996)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.36
, pp. 95-103
-
-
Haas-Kogan, D.A.1
Yount, G.2
Haas, M.3
Levi, D.4
Kogan, S.S.5
Hu, L.6
Vidair, C.7
Deen, D.F.8
Dewey, W.C.9
Israel, M.A.10
-
64
-
-
0031756707
-
Cytotoxicity and DNA fragmentation associated with sequential gemcitabine and 5-fluoro-2'-deoxyuridine in HT-29 colon cancer cells
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 2811-2818
-
-
Ren, Q.1
Kao, V.2
Grem, J.L.3
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