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Volumn 73, Issue 5, 1998, Pages 511-520

Radiosensitization of mouse sarcoma cells by fludarabine (F-ara-A) or gemcitabine (dFdC), two nucleoside analogues, is not mediated by an increased induction or a repair inhibition of DNA double-strand breaks as measured by pulsed-field gel electrophoresis

Author keywords

[No Author keywords available]

Indexed keywords

FLUDARABINE; GEMCITABINE;

EID: 7144264394     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530098142059     Document Type: Article
Times cited : (46)

References (51)
  • 1
    • 0019920433 scopus 로고
    • The effects of 9-β-D-arabinofuranosyladenine on the repair of DNA strand breaks in X-irradiated Ehrlich ascites tumour cells
    • BRYANT, P. E. and BLÖCHER, D., 1982, The effects of 9-β-D-arabinofuranosyladenine on the repair of DNA strand breaks in X-irradiated Ehrlich ascites tumour cells. International Journal of Radiation Biology, 42, 385-394.
    • (1982) International Journal of Radiation Biology , vol.42 , pp. 385-394
    • Bryant, P.E.1    Blöcher, D.2
  • 2
    • 0021317769 scopus 로고
    • Effects of ara-A and fresh medium on chromosome damage and DNA double-strand break repair in X-irradiated stationary cells
    • BRYANT, P. E., 1984, Effects of ara-A and fresh medium on chromosome damage and DNA double-strand break repair in X-irradiated stationary cells. British Journal of Cancer, 49 (suppl. VI), 61-65.
    • (1984) British Journal of Cancer , vol.49 , Issue.6 SUPPL. , pp. 61-65
    • Bryant, P.E.1
  • 3
    • 0025736690 scopus 로고
    • Inhibition of primer RNA formation in CCRF-CEM cells by fludarabine triphosphate
    • CATAPANO, C. V., CHANDLER, K. B. and FERNANDES, D. J., 1991, Inhibition of primer RNA formation in CCRF-CEM cells by fludarabine triphosphate. Cancer Research, 51, 1829-1835.
    • (1991) Cancer Research , vol.51 , pp. 1829-1835
    • Catapano, C.V.1    Chandler, K.B.2    Fernandes, D.J.3
  • 4
    • 0022991391 scopus 로고
    • 9-β-D-arabinofuranosyl-2-fluroadenine-5′-monophosphate pharmacokineties in plasma and tumours cells of patients with relapsed leukemia and lymphoma
    • DANHAUSER, L., PLUNKETT, W., KEATING, M. and CABANILLAS, F. 1986, 9-β-D-arabinofuranosyl-2-fluroadenine-5′-monophosphate pharmacokineties in plasma and tumours cells of patients with relapsed leukemia and lymphoma. Cancer Chemotherapy and Pharmacology, 18, 145-152.
    • (1986) Cancer Chemotherapy and Pharmacology , vol.18 , pp. 145-152
    • Danhauser, L.1    Plunkett, W.2    Keating, M.3    Cabanillas, F.4
  • 7
    • 0024421965 scopus 로고
    • Interaction of arabinosyl nucleotides in K562 human leukemia cells
    • GANDHI, V. and PLUNKETT, W. 1989, Interaction of arabinosyl nucleotides in K562 human leukemia cells. Biochemistry and Pharmacology, 38, 3351-3558.
    • (1989) Biochemistry and Pharmacology , vol.38 , pp. 3351-3558
    • Gandhi, V.1    Plunkett, W.2
  • 8
    • 0030707724 scopus 로고    scopus 로고
    • Kinetics of mouse jejunum radiosensitization by 2′,2′-difluorodeoxycytidine (gemcitabine) and its relationship with pharmacodynamics of DNA synthesis inhibition and cell cycle redistribution in crypt cells
    • GRÉGOIRE, V., BEAUDUIN, M., ROSIER, J-F., DE COSTER, B., BRUNIAUX, M., OCTAVE-PRIGNOT, M. and SCALLIET, P., 1997, Kinetics of mouse jejunum radiosensitization by 2′,2′-difluorodeoxycytidine (gemcitabine) and its relationship with pharmacodynamics of DNA synthesis inhibition and cell cycle redistribution in crypt cells. British Journal of Cancer, 76, 1315-1321.
    • (1997) British Journal of Cancer , vol.76 , pp. 1315-1321
    • Grégoire, V.1    Beauduin, M.2    Rosier, J.-F.3    De Coster, B.4    Bruniaux, M.5    Octave-Prignot, M.6    Scalliet, P.7
  • 10
    • 0013599829 scopus 로고    scopus 로고
    • Xucleoside analogs as radiosensitizing agents
    • edited by B. D. Cheson, M. J. Keating and W. Plunkett (New York: Marcel Dekker)
    • GRÉGOIRE, V and HITTELMAN, W., 1997, Xucleoside analogs as radiosensitizing agents. In Nucleoside Analogs In Cancer Therapy, edited by B. D. Cheson, M. J. Keating and W. Plunkett (New York: Marcel Dekker), pp. 315-358.
    • (1997) Nucleoside Analogs in Cancer Therapy , pp. 315-358
    • Grégoire, V.1    Hittelman, W.2
  • 14
    • 0028032726 scopus 로고
    • The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumours radiation response in vivo
    • GRÉGOIRE, V., VAN, N. T., BROCK, W. A., MILAS, L., PLUNKETT, W. and HITTELMAN, W. N., 1994c, The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumours radiation response in vivo. Cancer Research, 54, 6201-6209.
    • (1994) Cancer Research , vol.54 , pp. 6201-6209
    • Grégoire, V.1    Van, N.T.2    Brock, W.A.3    Milas, L.4    Plunkett, W.5    Hittelman, W.N.6
  • 15
    • 0023783698 scopus 로고
    • Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
    • HEINEMANN, V., HERTEL, L. W., GRINDEY, G. B. and PLUNKETT W., 1988, Comparison of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Research, 48, 4024-4031.
    • (1988) Cancer Research , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 16
    • 0026571795 scopus 로고
    • Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: A mechanism of self-potentiation
    • HEINEMANN, V., XU, Y-Z., CHUBB, S., SEN, A., HERTEL, L. W., GRINDEY, G. B. and PLUNKETT, W., 1992. Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: a mechanism of self-potentiation. Cancer Research, 52, 533-539.
    • (1992) Cancer Research , vol.52 , pp. 533-539
    • Heinemann, V.1    Xu, Y.-Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6    Plunkett, W.7
  • 17
    • 0017738023 scopus 로고
    • The effect of cytosine arabinoside on the frequency of single strand breaks in mammalian cells following irradiation or chemical treatment
    • HISS, F. A. and PRESTON R. J., 1977, The effect of cytosine arabinoside on the frequency of single strand breaks in mammalian cells following irradiation or chemical treatment. Biochimica et Biophysica Acta, 478, 1-8.
    • (1977) Biochimica et Biophysica Acta , vol.478 , pp. 1-8
    • Hiss, F.A.1    Preston, R.J.2
  • 20
    • 0025130572 scopus 로고
    • Termination of DNA synthesis by 9-β-D-arabinofuranosyl-2-fluoroadenosine: A mechanism for cytotoxicity
    • HUANG, P., CHUBB, S. and PLUNKETT, W., 1990, Termination of DNA synthesis by 9-β-D-arabinofuranosyl-2-fluoroadenosine: a mechanism for cytotoxicity. Journal of Biological Chemistry, 265, 16617-16625.
    • (1990) Journal of Biological Chemistry , vol.265 , pp. 16617-16625
    • Huang, P.1    Chubb, S.2    Plunkett, W.3
  • 22
    • 0037985941 scopus 로고    scopus 로고
    • Induction of apoptosis by nucleoside analogs
    • edited by B. D. Cheson, M. J. Keating and W. Plunkett (New York: Marcel Dekker)
    • HUANG, P. and WRIGHT, S., 1997, Induction of apoptosis by nucleoside analogs. In Nucleoside Analogs in Cancer Therapy, edited by B. D. Cheson, M. J. Keating and W. Plunkett (New York: Marcel Dekker), pp. 37-72.
    • (1997) Nucleoside Analogs in Cancer Therapy , pp. 37-72
    • Huang, P.1    Wright, S.2
  • 23
    • 0020611225 scopus 로고
    • Effects of the nucleoside analogues a-Ara-A, b-Ara-A and b-Ara-C on cell growth and repair of both potentially lethal damage and DNA double strand breaks in mammalian cells in culture
    • ILIAKIS, G. and BRYANT, P. E., 1983, Effects of the nucleoside analogues a-Ara-A, b-Ara-A and b-Ara-C on cell growth and repair of both potentially lethal damage and DNA double strand breaks in mammalian cells in culture. Anticancer Research, 3, 143-150.
    • (1983) Anticancer Research , vol.3 , pp. 143-150
    • Iliakis, G.1    Bryant, P.E.2
  • 24
    • 0024371477 scopus 로고
    • Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: Comparison with fixation of PLD
    • ILIAKIS, G., PANTELIAS, G., OKAYASU, R. and SEANER, R., 1989, Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: comparison with fixation of PLD. International Journal of Radiation Oncology, Biology, Physics, 16, 1261-1265.
    • (1989) International Journal of Radiation Oncology, Biology, Physics , vol.16 , pp. 1261-1265
    • Iliakis, G.1    Pantelias, G.2    Okayasu, R.3    Seaner, R.4
  • 25
    • 0000494957 scopus 로고
    • 9-β-D-arabinofuranosyl-2-fluroadenine (F-ara-A) inhibits both the fast and slow components of chromosome repair
    • edited by J. D. Chapman, W. C. Dewey and G. F. Whitmore (San Diego: Academic)
    • JAYANTH, R. V. and HITTELMAN, W. N., 1991, 9-β-D-arabinofuranosyl-2-fluroadenine (F-ara-A) inhibits both the fast and slow components of chromosome repair. In Radiation Research: A Twentieth-Century Perspective, vol. 1, edited by J. D. Chapman, W. C. Dewey and G. F. Whitmore (San Diego: Academic), pp. 411.
    • (1991) Radiation Research: A Twentieth-Century Perspective , vol.1 , pp. 411
    • Jayanth, R.V.1    Hittelman, W.N.2
  • 26
    • 0021205578 scopus 로고
    • The use of halogenated thymidine analogs as clinical radiosensitizers: Rationale, current status and future prospects: nonhypoxic sensitizers
    • KINSELLA, T. J., MITCHELL, J. B., RUSSO, A., MORSTYN, G. and GLASTEIN, E., 1984, The use of halogenated thymidine analogs as clinical radiosensitizers: rationale, current status and future prospects: nonhypoxic sensitizers. International Journal of Radiation Oncology, Biology, Physics, 10, 1399-1406.
    • (1984) International Journal of Radiation Oncology, Biology, Physics , vol.10 , pp. 1399-1406
    • Kinsella, T.J.1    Mitchell, J.B.2    Russo, A.3    Morstyn, G.4    Glastein, E.5
  • 28
    • 0030922494 scopus 로고    scopus 로고
    • Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′-difluoro-2′-deoxycytidine (gemcitabine)
    • LAWRENCE, T. S., CHANG, E., HAHN, T. M. and SHEWACH, D. S., 1997, Delayed radiosensitization of human colon carcinoma cells after a brief exposure to 2′,2′-difluoro-2′-deoxycytidine (gemcitabine). Clinical Cancer Research, 3, 777-782.
    • (1997) Clinical Cancer Research , vol.3 , pp. 777-782
    • Lawrence, T.S.1    Chang, E.2    Hahn, T.M.3    Shewach, D.S.4
  • 30
    • 0017362674 scopus 로고
    • A parametric method for estimation of dose-modifying factors: Low-dose extrapolation limit
    • MCLARTY, J. W. and THAMES, H. D., 1977, A parametric method for estimation of dose-modifying factors: low-dose extrapolation limit. Radiation Research, 69, 1-15.
    • (1977) Radiation Research , vol.69 , pp. 1-15
    • Mclarty, J.W.1    Thames, H.D.2
  • 31
    • 0029031276 scopus 로고
    • Tumor reoxygenation as a mechanism of taxol-induced enhancement of tumours radioresponse
    • MILAS L., HUNTER N., MASON K. A., MILROSS C. and PETERS L. J., 1995, Tumor reoxygenation as a mechanism of taxol-induced enhancement of tumours radioresponse. Acta Oncolologica, 34, 409-4012.
    • (1995) Acta Oncolologica , vol.34 , pp. 409-4012
    • Milas, L.1    Hunter, N.2    Mason, K.A.3    Milross, C.4    Peters, L.J.5
  • 32
    • 0023405469 scopus 로고
    • The effect of 9-beta-D-arabinofuranosyladenine on the formation of X-ray induced chromatid aberrations in X-irradiated G2 human cells
    • MOZDARANI H. and BRYANT P. E., 1987, The effect of 9-beta-D-arabinofuranosyladenine on the formation of X-ray induced chromatid aberrations in X-irradiated G2 human cells. Mutagenesis, 2, 371-374.
    • (1987) Mutagenesis , vol.2 , pp. 371-374
    • Mozdarani, H.1    Bryant, P.E.2
  • 35
    • 0000924845 scopus 로고    scopus 로고
    • New antimetabolites in preclinical and clinical development
    • PETERS, G. J AND ACKLAND, S. P., 1996, New antimetabolites in preclinical and clinical development. Exp. Opinion in Investigation Drugs. 5, 637-679.
    • (1996) Exp. Opinion in Investigation Drugs , vol.5 , pp. 637-679
    • Peters, G.J.1    Ackland, S.P.2
  • 37
    • 0002440308 scopus 로고    scopus 로고
    • Nucleoside analogs: Cellular pharmacology, mechanisms of action and strategies for combination therapy
    • edited by B. D. Cheson, M. J. Keating and W. Plunkett (New York: Marcel Dekker)
    • PLUNKETT, W. and GANDHI, V., 1997, Nucleoside analogs: cellular pharmacology, mechanisms of action and strategies for combination therapy. In Nucleoside Analogs in Cancer Therapy, edited by B. D. Cheson, M. J. Keating and W. Plunkett (New York: Marcel Dekker), pp. 1-36.
    • (1997) Nucleoside Analogs in Cancer Therapy , pp. 1-36
    • Plunkett, W.1    Gandhi, V.2
  • 38
    • 0037985936 scopus 로고
    • Radiation damage to DNA and its repair in the formation of chromosome aberrations
    • edited by A. R. Lin (New York: Alan R. Liss)
    • PRESTON, R. J., 1983, Radiation damage to DNA and its repair in the formation of chromosome aberrations. In Radiation-Induced Chromosome Damage in Man, edited by A. R. Lin (New York: Alan R. Liss), pp. 111-125.
    • (1983) Radiation-Induced Chromosome Damage in Man , pp. 111-125
    • Preston, R.J.1
  • 39
    • 0026984625 scopus 로고
    • Effect of 2′,2′-difluorodeoxycytidine on the viability and radiosensitivity of EMT6 cells in vitro
    • ROCKWELL, S. and GRINDEY, G. B., 1992, Effect of 2′,2′-difluorodeoxycytidine on the viability and radiosensitivity of EMT6 cells in vitro. Oncology Research, 4, 151-155.
    • (1992) Oncology Research , vol.4 , pp. 151-155
    • Rockwell, S.1    Grindey, G.B.2
  • 41
    • 0028105119 scopus 로고
    • Schedule dependence of sensitivity to 2′,2′-Difluorodeoxycytidine (gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours
    • RUIZ VAN HAPPEREN V. W. T., VEERMAN G., BOVEN E., NOORDHUIS P., VERMOKEN J. B. and PETERS G. J., 1994, Schedule dependence of sensitivity to 2′,2′-Difluorodeoxycytidine (gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours. Biochemical Pharmacology, 48, 1327-1839.
    • (1994) Biochemical Pharmacology , vol.48 , pp. 1327-1839
    • Ruiz Van Happeren, V.W.T.1    Veerman, G.2    Boven, E.3    Noordhuis, P.4    Vermoken, J.B.5    Peters, G.J.6
  • 42
    • 0029859821 scopus 로고    scopus 로고
    • Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes
    • SANDOVAL, A.,CONSOLI, U. and PLUNKETT, W., 1996, Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes. Clinical Cancer Research, 2, 1731-1741.
    • (1996) Clinical Cancer Research , vol.2 , pp. 1731-1741
    • Sandoval, A.1    Consoli, U.2    Plunkett, W.3
  • 43
    • 0028240063 scopus 로고
    • Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells
    • SHEWACH, D. S., HAHN, T. M., CHANG, E., HERTEL, L. W. and LAWRENCE, T. S., 1904, Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells. Cancer Research, 54, 3218-3223.
    • (1904) Cancer Research , vol.54 , pp. 3218-3223
    • Shewach, D.S.1    Hahn, T.M.2    Chang, E.3    Hertel, L.W.4    Lawrence, T.S.5
  • 44
    • 0028839329 scopus 로고
    • Radiosensitization of human tumours cells by gemcitabine in vitro
    • SHEWACH, D. S. and LAWRENCE, T. S., 1995, Radiosensitization of human tumours cells by gemcitabine in vitro. Seminar in Oncology, 22 (suppl. II), 68-71.
    • (1995) Seminar in Oncology , vol.22 , Issue.2 SUPPL. , pp. 68-71
    • Shewach, D.S.1    Lawrence, T.S.2
  • 45
    • 0020058465 scopus 로고
    • In vitro biological activity of 9-β-D-arabinofuranosyl-2-fluoroadenosine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells
    • TSENG, W. C., DERSE, D., CHENG, Y. C., BROCKMAN, R. W. and BENNETT, L. L. JR., 1982, In vitro biological activity of 9-β-D-arabinofuranosyl-2-fluoroadenosine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells. Molecular Pharmacology, 21, 474-477.
    • (1982) Molecular Pharmacology , vol.21 , pp. 474-477
    • Tseng, W.C.1    Derse, D.2    Cheng, Y.C.3    Brockman, R.W.4    Bennett Jr., L.L.5
  • 46
    • 0021365312 scopus 로고
    • Effects of inhibitors of DNA strand break repair on HeLa cell radiosensitivity
    • WARD, J. F., JONER, E. I. and BLAKELY, W. F., 1984, Effects of inhibitors of DNA strand break repair on HeLa cell radiosensitivity. Cancer Research, 44, 59-63.
    • (1984) Cancer Research , vol.44 , pp. 59-63
    • Ward, J.F.1    Joner, E.I.2    Blakely, W.F.3
  • 47
    • 0022312389 scopus 로고
    • Biochemistry of DNA lesions
    • WARD, J. F., 1985, Biochemistry of DNA lesions. Radiation Research, 104, S103-111.
    • (1985) Radiation Research , vol.104
    • Ward, J.F.1
  • 48
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation and reparability
    • WARD, J. F., 1988, DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation and reparability. Progress in Nucleic Acid Molecular Biology, 35, 95-125.
    • (1988) Progress in Nucleic Acid Molecular Biology , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 51
    • 0026801110 scopus 로고
    • Dual mode of inhibition of purified DNA ligase I from human cells by 9-β-D-arabinofuranosyl-2-fluoroadenosine
    • YANG, S. W., HUANG, P., PLUNKETT, W., BECKER, F. F. and CHAN, J. Y. H., 1992, Dual mode of inhibition of purified DNA ligase I from human cells by 9-β-D-arabinofuranosyl-2-fluoroadenosine. Journal of Biological Chemistry, 267, 2345-2349.
    • (1992) Journal of Biological Chemistry , vol.267 , pp. 2345-2349
    • Yang, S.W.1    Huang, P.2    Plunkett, W.3    Becker, F.F.4    Chan, J.Y.H.5


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