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Volumn 11, Issue 1, 1996, Pages 31-38

Human antibody variable region gene usage in HIV-1 infection

Author keywords

Antibody gene usage; Heavy chain variable region; Human immunodeficiency virus type 1; Human monoclonal antibodies

Indexed keywords

ANTIBODY PRODUCTION; ANTIBODY STRUCTURE; GENE EXPRESSION; GENE STRUCTURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOGLOBULIN VARIABLE REGION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 0030026943     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199601010-00004     Document Type: Review
Times cited : (21)

References (57)
  • 1
    • 85012474693 scopus 로고
    • New concepts in the immunopathogenesis of human immunodeficiency virus infection
    • Pantaleo G, Graziosi C, Fauci AS. New concepts in the immunopathogenesis of human immunodeficiency virus infection. N Engl J Med 1993;328:327-33.
    • (1993) N Engl J Med , vol.328 , pp. 327-333
    • Pantaleo, G.1    Graziosi, C.2    Fauci, A.S.3
  • 2
    • 0024404415 scopus 로고
    • HIV-1-specific B-cell activation: A major constituent of spontaneous B cell activation during HIV-1 infection
    • Amadori A, Zamarchi R, Ciminale V, et al. HIV-1-specific B-cell activation: a major constituent of spontaneous B cell activation during HIV-1 infection. J Immunol 1989;143: 2146-52.
    • (1989) J Immunol , vol.143 , pp. 2146-2152
    • Amadori, A.1    Zamarchi, R.2    Ciminale, V.3
  • 3
    • 0023927940 scopus 로고
    • Lymphoid neoplasia associated with the acquired immune deficiency syndrome
    • Knowles D, Chamulak G, Subar M, et al. Lymphoid neoplasia associated with the acquired immune deficiency syndrome. Ann Intern Med 1988;108:744-9.
    • (1988) Ann Intern Med , vol.108 , pp. 744-749
    • Knowles, D.1    Chamulak, G.2    Subar, M.3
  • 4
    • 0025500474 scopus 로고
    • B-cell activation and HIV-1 infection: Deeds and misdeeds
    • Amadori A, Chieco-Bianchi L, B-cell activation and HIV-1 infection: deeds and misdeeds. Immunol Today 1990;11: 374-9.
    • (1990) Immunol Today , vol.11 , pp. 374-379
    • Amadori, A.1    Chieco-Bianchi, L.2
  • 5
    • 0027488833 scopus 로고
    • B-cell abnormalities in AIDS: Stable and clonally restricted antibody response in HIV-1 infection
    • Muller S, Wang H, Silverman G, Bramlet G, Haigwood N, Kohler H. B-cell abnormalities in AIDS: stable and clonally restricted antibody response in HIV-1 infection. Scand J Immunol 1993;38:327-34.
    • (1993) Scand J Immunol , vol.38 , pp. 327-334
    • Muller, S.1    Wang, H.2    Silverman, G.3    Bramlet, G.4    Haigwood, N.5    Kohler, H.6
  • 7
    • 0025868277 scopus 로고
    • Molecular characterization of five anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response
    • Andris JS, Johnson S, Zolla-Pazner S, Capra JD. Molecular characterization of five anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response. Proc Natl Acad Sci USA 1991;88:7783-8.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7783-7788
    • Andris, J.S.1    Johnson, S.2    Zolla-Pazner, S.3    Capra, J.D.4
  • 8
    • 43949157657 scopus 로고
    • Deceptive imprinting in the immune response against HIV-1
    • Kohler H, Muller S, Nara P. Deceptive imprinting in the immune response against HIV-1. Immunol Today 1994;15: 475-8.
    • (1994) Immunol Today , vol.15 , pp. 475-478
    • Kohler, H.1    Muller, S.2    Nara, P.3
  • 10
    • 0028217004 scopus 로고
    • Immunoglobulin V regions and the B cell
    • Stewart A, Schwartz R. Immunoglobulin V regions and the B cell. Blood 1994;83:1717-30.
    • (1994) Blood , vol.83 , pp. 1717-1730
    • Stewart, A.1    Schwartz, R.2
  • 11
    • 0025787513 scopus 로고
    • Restricted Ig heavy chain V gene usage in the human antibody response to Hemophilus influenza capsular polysaccharide
    • Adderson EE, Shackelford PG, Quinn A, Carroll WL. Restricted Ig heavy chain V gene usage in the human antibody response to Hemophilus influenza capsular polysaccharide. J Immunol 1991;147:1667-74.
    • (1991) J Immunol , vol.147 , pp. 1667-1674
    • Adderson, E.E.1    Shackelford, P.G.2    Quinn, A.3    Carroll, W.L.4
  • 13
    • 0009466478 scopus 로고
    • Restricted usage of immunoglobulin variable-region genes in human autoantibodies
    • Honjo T, Alt FW, Rabbitts TH, eds., San Diego: Academic Press
    • Newkirk MM, Capra JD. Restricted usage of immunoglobulin variable-region genes in human autoantibodies, 203-220. In: Honjo T, Alt FW, Rabbitts TH, eds., The immunoglobulin genes. San Diego: Academic Press, 1990.
    • (1990) The Immunoglobulin Genes , pp. 203-220
    • Newkirk, M.M.1    Capra, J.D.2
  • 14
    • 0000634555 scopus 로고
    • Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia
    • Kipps TJ, Tomhaven E, Pratt LF, Duffy S, Chen PP, Carson DA. Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 1989;86:5913-21.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5913-5921
    • Kipps, T.J.1    Tomhaven, E.2    Pratt, L.F.3    Duffy, S.4    Chen, P.P.5    Carson, D.A.6
  • 16
    • 0023525849 scopus 로고
    • Early restriction of the human antibody repertoire
    • Schroeder HW, Hillson JL, Perlmutter RM. Early restriction of the human antibody repertoire. Science 1987;2328: 791-5.
    • (1987) Science , vol.2328 , pp. 791-795
    • Schroeder, H.W.1    Hillson, J.L.2    Perlmutter, R.M.3
  • 17
    • 0025907671 scopus 로고
    • + B lymphocytes
    • Weiss L, eds. Washington, D.C.: The Society for Experimental Biology and Medicine
    • + B lymphocytes. In: Weiss L, eds. Bone and the immune system. Washington, D.C.: The Society for Experimental Biology and Medicine, 1991:226-41.
    • (1991) Bone and the Immune System , pp. 226-241
    • Kasain, M.1    Ikematsu, H.2    Casali, P.3
  • 18
    • 0023688171 scopus 로고
    • Restricted heterogeneity of antibody to gp120 and p24 in AIDS
    • Grimaldi L, Roos R, Devare S, et al. Restricted heterogeneity of antibody to gp120 and p24 in AIDS. J Immunol 1988; 141:114-7.
    • (1988) J Immunol , vol.141 , pp. 114-117
    • Grimaldi, L.1    Roos, R.2    Devare, S.3
  • 19
    • 0025119215 scopus 로고
    • IgG oligoclonal bands in sera of HIV-l-infected patients are mainly directed against HIV-1 determinants
    • Amadori A, Gallo P, Zamarchi R, et al. IgG oligoclonal bands in sera of HIV-l-infected patients are mainly directed against HIV-1 determinants. AIDS Res Hum Retrovir 1990; 6:581-6.
    • (1990) AIDS Res Hum Retrovir , vol.6 , pp. 581-586
    • Amadori, A.1    Gallo, P.2    Zamarchi, R.3
  • 20
    • 0026675432 scopus 로고
    • Spectrotype of antigp120 antibodies remains stable over the course of HIV-1 disease
    • Amelio R, Bisselli R, Nisini R, et al. Spectrotype of antigp120 antibodies remains stable over the course of HIV-1 disease. J Acquir Immune Defic Syndr 1992;5:930-5.
    • (1992) J Acquir Immune Defic Syndr , vol.5 , pp. 930-935
    • Amelio, R.1    Bisselli, R.2    Nisini, R.3
  • 21
    • 0025775863 scopus 로고
    • Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/ CD4 binding in HIV-1 infected humans
    • Kang C, Nara P, Chamat S, et al. Evidence for non-V3-specific neutralizing antibodies that interfere with gp120/ CD4 binding in HIV-1 infected humans. Proc Natl Acad Sci USA 1991;88:6171-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6171-6175
    • Kang, C.1    Nara, P.2    Chamat, S.3
  • 22
    • 0026663512 scopus 로고
    • Two major groups of neutralizing anti-gp120 antibodies exist in HIV-1 infected individuals: Evidence for epitope diversity around the CD4 attachment site
    • Chamat S, Nara P, Berquist L, et al. Two major groups of neutralizing anti-gp120 antibodies exist in HIV-1 infected individuals: evidence for epitope diversity around the CD4 attachment site. J Immunol 1992;149:649-55.
    • (1992) J Immunol , vol.149 , pp. 649-655
    • Chamat, S.1    Nara, P.2    Berquist, L.3
  • 23
    • 0026776364 scopus 로고
    • Human monoclonal and polyclonal anti-HIV-1 antibodies share a common clonotypic specificity
    • Wang H, Muller S, Zolla-Pazner H. Human monoclonal and polyclonal anti-HIV-1 antibodies share a common clonotypic specificity. Eur J Immunol 1992;22:1749-55.
    • (1992) Eur J Immunol , vol.22 , pp. 1749-1755
    • Wang, H.1    Muller, S.2    Zolla-Pazner, H.3
  • 24
    • 0008607557 scopus 로고
    • Concept of idiotypic network: Description and functions
    • Cerny J, Hiernaux J, eds. Washington, D.C.: American Society for Microbiology
    • Cerny J, Hiernaux J. Concept of idiotypic network: description and functions. In: Cerny J, Hiernaux J, eds. Idiotypic network and disease: Washington, D.C.: American Society for Microbiology, 1990:13-29.
    • (1990) Idiotypic Network and Disease , pp. 13-29
    • Cerny, J.1    Hiernaux, J.2
  • 25
    • 0026462782 scopus 로고
    • Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody
    • Marasco WA, Bagley J, Zani C, et al. Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody. J Clin Invest 1992;90:1467-72.
    • (1992) J Clin Invest , vol.90 , pp. 1467-1472
    • Marasco, W.A.1    Bagley, J.2    Zani, C.3
  • 26
    • 0025160356 scopus 로고
    • Nucleotide sequence of the cDNA encoding the V-regions of the H- and L-chains of a human monoclonal antibody specific to HIV-1 gp41
    • Felgenhauer M, Kohl J, Ruker F. Nucleotide sequence of the cDNA encoding the V-regions of the H- and L-chains of a human monoclonal antibody specific to HIV-1 gp41. Nucl Acids Res 1990;18:4927.
    • (1990) Nucl Acids Res , vol.18 , pp. 4927
    • Felgenhauer, M.1    Kohl, J.2    Ruker, F.3
  • 27
    • 0027367543 scopus 로고
    • Variable region genes of anti-HIV-1 human monoclonal antibodies: Non-restricted use of the V gene repertoire and extensive somatic mutation
    • Moran M, Andris J, Matsumato Y, Capra D, Hersh E. Variable region genes of anti-HIV-1 human monoclonal antibodies: non-restricted use of the V gene repertoire and extensive somatic mutation. Mol Immunol 1993;30:1543-51.
    • (1993) Mol Immunol , vol.30 , pp. 1543-1551
    • Moran, M.1    Andris, J.2    Matsumato, Y.3    Capra, D.4    Hersh, E.5
  • 28
    • 0028001662 scopus 로고
    • Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120
    • Bagley J, Dillon P, Rosen C, Robbinson J, Sodroski J, Marasco W. Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120. Mol Immunol 1994;31:1149-60.
    • (1994) Mol Immunol , vol.31 , pp. 1149-1160
    • Bagley, J.1    Dillon, P.2    Rosen, C.3    Robbinson, J.4    Sodroski, J.5    Marasco, W.6
  • 30
    • 0025921519 scopus 로고
    • H gene family utilization in human peripheral B cells by in situ hybridization
    • H gene family utilization in human peripheral B cells by in situ hybridization. J Immunol 1991;146:2855-64.
    • (1991) J Immunol , vol.146 , pp. 2855-2864
    • Zouali, M.1    Theze, J.2
  • 31
    • 0027223565 scopus 로고
    • Molecular profile of an antibody response to HIV-1 as probed by combinatorial phage display libraries
    • Barbas C, Collet T, Amberg W, et al. Molecular profile of an antibody response to HIV-1 as probed by combinatorial phage display libraries. J Mol Biol 1993;230:812-23.
    • (1993) J Mol Biol , vol.230 , pp. 812-823
    • Barbas, C.1    Collet, T.2    Amberg, W.3
  • 32
    • 0025370699 scopus 로고
    • Evolving abundance and clonal pattern of human germinal center B cells during childhood
    • Valles-Ayoub Y, Govan H, Braun J. Evolving abundance and clonal pattern of human germinal center B cells during childhood. Blood 1990;76:7-12.
    • (1990) Blood , vol.76 , pp. 7-12
    • Valles-Ayoub, Y.1    Govan, H.2    Braun, J.3
  • 35
    • 37049178741 scopus 로고
    • The Staphylococcal enterotoxins and their relatives
    • Marrack P, Kappler J. The Staphylococcal enterotoxins and their relatives. Science 1990;248:705-11.
    • (1990) Science , vol.248 , pp. 705-711
    • Marrack, P.1    Kappler, J.2
  • 36
    • 0027475327 scopus 로고
    • Structure and physical map of 64 variable segments in the 3′ 0.8-megabase region of the human immunoglobulin heavy chain locus
    • Matsuda F, Shin E, Nagaoka H, et al. Structure and physical map of 64 variable segments in the 3′ 0.8-megabase region of the human immunoglobulin heavy chain locus. Nature Genet 1993;3:88-94.
    • (1993) Nature Genet , vol.3 , pp. 88-94
    • Matsuda, F.1    Shin, E.2    Nagaoka, H.3
  • 37
    • 43949158538 scopus 로고
    • The Th1-Th2 hypothesis of HIV-1 infection: New insights
    • Clerici M, Shearer G. The Th1-Th2 hypothesis of HIV-1 infection: new insights. Immunol Today 1994;15:575-81.
    • (1994) Immunol Today , vol.15 , pp. 575-581
    • Clerici, M.1    Shearer, G.2
  • 39
    • 1542570366 scopus 로고
    • Elevated serum IL-6 in patients with common variable immunodeficiency associated with a failure in B-cell differentiation
    • Adelman D, Matsuda T, Hirano T, Kishimoto T, Saxon A. Elevated serum IL-6 in patients with common variable immunodeficiency associated with a failure in B-cell differentiation. J Allergy Clin Immunol 1990;86:1512-20.
    • (1990) J Allergy Clin Immunol , vol.86 , pp. 1512-1520
    • Adelman, D.1    Matsuda, T.2    Hirano, T.3    Kishimoto, T.4    Saxon, A.5
  • 40
    • 0023719496 scopus 로고
    • Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency
    • Sherr E, Adelman D, Saxon A, Gilly M, Wall R, Sidell N. Retinoic acid induces the differentiation of B cell hybridomas from patients with common variable immunodeficiency. J Exp Med 1988;168:55-60.
    • (1988) J Exp Med , vol.168 , pp. 55-60
    • Sherr, E.1    Adelman, D.2    Saxon, A.3    Gilly, M.4    Wall, R.5    Sidell, N.6
  • 41
    • 0024395025 scopus 로고
    • Failure of B cells in common variable immunodeficiency to transit from proliferation to differentiation is associated with altered B cell surface molecule display
    • Saxon A, Giorgi J, Sherr E, Kagan J. Failure of B cells in common variable immunodeficiency to transit from proliferation to differentiation is associated with altered B cell surface molecule display. J Allergy Clin Immunol 1989;84:44-9.
    • (1989) J Allergy Clin Immunol , vol.84 , pp. 44-49
    • Saxon, A.1    Giorgi, J.2    Sherr, E.3    Kagan, J.4
  • 42
    • 0025144869 scopus 로고
    • Structural characterization of the second major cross reactive idiotype group of rheumatoid factors
    • Silverman G, Schohenoler R, Accavitti M, Koopman W, Carson D. Structural characterization of the second major cross reactive idiotype group of rheumatoid factors. Arthritis Rheum 1990;33:1347-60.
    • (1990) Arthritis Rheum , vol.33 , pp. 1347-1360
    • Silverman, G.1    Schohenoler, R.2    Accavitti, M.3    Koopman, W.4    Carson, D.5
  • 46
    • 0024367292 scopus 로고
    • A hybridoma producing human monoclonal antibody specific for glycoprotein 120 kDa of HIV-1
    • Lake D, Sugano T, Matsumoto Y, Peterson E, Feorino P, Hersh E. A hybridoma producing human monoclonal antibody specific for glycoprotein 120 kDa of HIV-1. Life Sci 1989;45:iii-x.
    • (1989) Life Sci , vol.45
    • Lake, D.1    Sugano, T.2    Matsumoto, Y.3    Peterson, E.4    Feorino, P.5    Hersh, E.6
  • 47
    • 0026574967 scopus 로고
    • Generation and characterization of a human monoclonal antibody that neutralizes diverse HIV-1 isolates in vitro
    • Lake D, Kawamura T, Tomiyama T, et al. Generation and characterization of a human monoclonal antibody that neutralizes diverse HIV-1 isolates in vitro. AIDS 1992;6:17-242.
    • (1992) AIDS , vol.6 , pp. 17-242
    • Lake, D.1    Kawamura, T.2    Tomiyama, T.3
  • 48
    • 0023684227 scopus 로고
    • Human monoclonal antibodies against glycoproteins of HIV-1
    • Sugano T, Masuho Y, Matsumoto Y, et al. Human monoclonal antibodies against glycoproteins of HIV-1. Biochem Biophys Res Commun 1988;155:1105-12.
    • (1988) Biochem Biophys Res Commun , vol.155 , pp. 1105-1112
    • Sugano, T.1    Masuho, Y.2    Matsumoto, Y.3
  • 49
    • 0027290678 scopus 로고
    • Further characterization of an antigenic site of HIV-1 gp120 recognized by virus neutralizing human monoclonal antibodies
    • Schutten M, McNight A, Huisman R, et al. Further characterization of an antigenic site of HIV-1 gp120 recognized by virus neutralizing human monoclonal antibodies. AIDS 1993;7:919-23.
    • (1993) AIDS , vol.7 , pp. 919-923
    • Schutten, M.1    McNight, A.2    Huisman, R.3
  • 51
    • 0026801056 scopus 로고
    • Discontinuous, conserved neutralization epitopes overlapping the CD4 binding region of HIV-1 gp120 glycoprotein
    • Thali M, Furman C. Ho D, et al. Discontinuous, conserved neutralization epitopes overlapping the CD4 binding region of HIV-1 gp120 glycoprotein. J Virol 1992;66:5635-41.
    • (1992) J Virol , vol.66 , pp. 5635-5641
    • Thali, M.1    Furman, C.2    Ho, D.3
  • 52
    • 0023846025 scopus 로고
    • The high efficiency, human B cell immortalizing heteromyeloma CB-F7
    • Grunow R, Jahn S, Porstmann T, et al. The high efficiency, human B cell immortalizing heteromyeloma CB-F7. J Immunol Meth 1988;106:257-65.
    • (1988) J Immunol Meth , vol.106 , pp. 257-265
    • Grunow, R.1    Jahn, S.2    Porstmann, T.3
  • 53
    • 0024415389 scopus 로고
    • Pilot scale production of a human monoclonal antibody against HIV-1
    • Jungbauer A, Tauer C, Wenisch E, et al. Pilot scale production of a human monoclonal antibody against HIV-1. J Biochem Biophys Meth 1989;19:223-9.
    • (1989) J Biochem Biophys Meth , vol.19 , pp. 223-229
    • Jungbauer, A.1    Tauer, C.2    Wenisch, E.3
  • 54
    • 0025958022 scopus 로고
    • Conformational epitope on gp120 important in CD4 binding and HIV-1 neutralization identified by a human monoclonal antibody
    • Ho D, McKeating J, Li X, et al. Conformational epitope on gp120 important in CD4 binding and HIV-1 neutralization identified by a human monoclonal antibody. J Virol 1991;65: 489-93.
    • (1991) J Virol , vol.65 , pp. 489-493
    • Ho, D.1    McKeating, J.2    Li, X.3
  • 56
    • 0026356679 scopus 로고
    • Production of site selected neutralizing human monoclonal antibodies against the third variable domain of HIV-1 envelope glycoprotein
    • Gorny M, Xu J, Gianakakos V, et al. Production of site selected neutralizing human monoclonal antibodies against the third variable domain of HIV-1 envelope glycoprotein. Proc Natl Acad Sci USA 1991;88:3238-42.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 3238-3242
    • Gorny, M.1    Xu, J.2    Gianakakos, V.3
  • 57
    • 0026001658 scopus 로고
    • An IgG human monoclonal antibody which reacts with HIV-l/gp120, inhibits virus binding to cells, and neutralizes infection
    • Posner M, Hideshima T, Cannon T, Mukherjee M, Mayer K, Bryn R. An IgG human monoclonal antibody which reacts with HIV-l/gp120, inhibits virus binding to cells, and neutralizes infection. J Immunol 1991;146:4325-32.
    • (1991) J Immunol , vol.146 , pp. 4325-4332
    • Posner, M.1    Hideshima, T.2    Cannon, T.3    Mukherjee, M.4    Mayer, K.5    Bryn, R.6


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