-
1
-
-
0032400513
-
Somatic hypermutation in T-independent and T-dependent immune responses to Haemophilus influenzae type b polysaccharide
-
Adderson, E. E., P. G. Shackelford, and W. L. Carroll. 1998. Somatic hypermutation in T-independent and T-dependent immune responses to Haemophilus influenzae type b polysaccharide. Clin. Immunol. Immunopathol. 89:240-246.
-
(1998)
Clin. Immunol. Immunopathol.
, vol.89
, pp. 240-246
-
-
Adderson, E.E.1
Shackelford, P.G.2
Carroll, W.L.3
-
2
-
-
0027216150
-
Restricted immunoglobulin VH usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of mono-specific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens
-
Adderson, E. E., P. G. Shackelford, A. Quinn, P. M. Wilson, M. W. Cunningham, R. A. Insel, and W. L. Carroll. 1993. Restricted immunoglobulin VH usage and VDJ combinations in the human response to Haemophilus influenzae type b capsular polysaccharide. Nucleotide sequences of mono-specific anti-Haemophilus antibodies and polyspecific antibodies cross-reacting with self antigens. J. Clin. Investig. 91:2734-2743.
-
(1993)
J. Clin. Investig.
, vol.91
, pp. 2734-2743
-
-
Adderson, E.E.1
Shackelford, P.G.2
Quinn, A.3
Wilson, P.M.4
Cunningham, M.W.5
Insel, R.A.6
Carroll, W.L.7
-
3
-
-
0032532032
-
Haemophilus influenzae type b polysaccharide-protein conjugate vaccine elicits a more diverse antibody repertoire in infants than in adults
-
Adderson, E. E., P. M. Wilson, M. W. Cunningham, and P. G. Shackelford. 1998. Haemophilus influenzae type b polysaccharide-protein conjugate vaccine elicits a more diverse antibody repertoire in infants than in adults. J. Immunol. 161:4177-4182.
-
(1998)
J. Immunol.
, vol.161
, pp. 4177-4182
-
-
Adderson, E.E.1
Wilson, P.M.2
Cunningham, M.W.3
Shackelford, P.G.4
-
4
-
-
0024044570
-
Antibody engineering for the analysis of affinity maturation of an anti-hapten response
-
Allen, D., T. Simon, F. Sablitzky, K. Rajewsky, and A. Cumano. 1988. Antibody engineering for the analysis of affinity maturation of an anti-hapten response. EMBO J. 7:1995-2001.
-
(1988)
EMBO J.
, vol.7
, pp. 1995-2001
-
-
Allen, D.1
Simon, T.2
Sablitzky, F.3
Rajewsky, K.4
Cumano, A.5
-
5
-
-
0017058503
-
The quellung reaction, a neglected microbiologic technique
-
Austrian, R. 1976. The quellung reaction, a neglected microbiologic technique. Mt. Sinai J. Med. 43:699-709.
-
(1976)
Mt. Sinai J. Med.
, vol.43
, pp. 699-709
-
-
Austrian, R.1
-
6
-
-
0034004886
-
Immunogenetic analysis of the immune response to pneumococcal polysaccharide
-
Baxendale, H. E., Z. Davis, H. N. White, M. B. Spellerberg, F. K. Stevenson, and D. Goldblatt. 2000. Immunogenetic analysis of the immune response to pneumococcal polysaccharide. Eur. J. Immunol. 30:1214-1223.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 1214-1223
-
-
Baxendale, H.E.1
Davis, Z.2
White, H.N.3
Spellerberg, M.B.4
Stevenson, F.K.5
Goldblatt, D.6
-
7
-
-
25444490970
-
Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection
-
Bose, B., and S. Sinha. 2005. Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection. Immunology 116:172-183.
-
(2005)
Immunology
, vol.116
, pp. 172-183
-
-
Bose, B.1
Sinha, S.2
-
8
-
-
0027932998
-
The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement
-
Chang, B., and P. Casali. 1994. The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement. Immunol. Today 15:367-373.
-
(1994)
Immunol. Today
, vol.15
, pp. 367-373
-
-
Chang, B.1
Casali, P.2
-
9
-
-
0034022546
-
A pneumococcal capsular polysaccharide vaccine induces a repertoire shift with increased VH3 expression in peripheral B cells from human immunodeficiency virus (HIV)-uninfected but not HIV-infected persons
-
Chang, Q., J. Abadi, P. Alpert, and L. Pirofski. 2000. A pneumococcal capsular polysaccharide vaccine induces a repertoire shift with increased VH3 expression in peripheral B cells from human immunodeficiency virus (HIV)-uninfected but not HIV-infected persons. J. Infect. Dis. 181:1313-1321.
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 1313-1321
-
-
Chang, Q.1
Abadi, J.2
Alpert, P.3
Pirofski, L.4
-
10
-
-
0026782875
-
Generation and analysis of random point mutations in an antibody CDR2 sequence: Many mutated antibodies lose their ability to bind antigen
-
Chen, C., V. A. Roberts, and M. B. Rittenberg. 1992. Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigen. J. Exp. Med. 176:855-866.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 855-866
-
-
Chen, C.1
Roberts, V.A.2
Rittenberg, M.B.3
-
11
-
-
0029047689
-
Enhancement and destruction of antibody function by somatic mutation: Unequal occurrence is controlled by V gene combinatorial associations
-
Chen, C., V. A. Roberts, S. Stevens, M. Brown, P. M. Stenzel, and M. B. Rittenberg. 1995. Enhancement and destruction of antibody function by somatic mutation: unequal occurrence is controlled by V gene combinatorial associations. EMBO J. 14:2784-2794.
-
(1995)
EMBO J.
, vol.14
, pp. 2784-2794
-
-
Chen, C.1
Roberts, V.A.2
Stevens, S.3
Brown, M.4
Stenzel, P.M.5
Rittenberg, M.B.6
-
12
-
-
0032031498
-
Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes
-
Dunn, W. D., A. Dogan, L. Boursier, C. M. MacDonald, and J. Spencer. 1998. Base-specific sequences that bias somatic hypermutation deduced by analysis of out-of-frame human IgVH genes. J. Immunol. 160:2360-2364.
-
(1998)
J. Immunol.
, vol.160
, pp. 2360-2364
-
-
Dunn, W.D.1
Dogan, A.2
Boursier, L.3
MacDonald, C.M.4
Spencer, J.5
-
13
-
-
0031764112
-
Strong intrinsic biases towards mutation and conservation of bases in human IgVH genes during somatic hypermutation prevent statistical analysis of antigen selection
-
Dunn, W. D., and J. Spencer. 1998. Strong intrinsic biases towards mutation and conservation of bases in human IgVH genes during somatic hypermutation prevent statistical analysis of antigen selection. Immunology 95:339-345.
-
(1998)
Immunology
, vol.95
, pp. 339-345
-
-
Dunn, W.D.1
Spencer, J.2
-
14
-
-
0033999821
-
Immunogenicity of pneumococcal conjugate vaccines
-
Eskola, J. 2000. Immunogenicity of pneumococcal conjugate vaccines. Pediatr. Infect. Dis. J. 19:388-393.
-
(2000)
Pediatr. Infect. Dis. J.
, vol.19
, pp. 388-393
-
-
Eskola, J.1
-
15
-
-
0036467608
-
Natural and vaccine-induced immunity and immunologic memory to Neisseria meningitidis serogroup C in young adults
-
Goldblatt, D., R. Borrow, and E. Miller. 2002. Natural and vaccine-induced immunity and immunologic memory to Neisseria meningitidis serogroup C in young adults. J. Infect. Dis. 185:397-400.
-
(2002)
J. Infect. Dis.
, vol.185
, pp. 397-400
-
-
Goldblatt, D.1
Borrow, R.2
Miller, E.3
-
16
-
-
0027717510
-
The role of pH in modified ELISA procedures used for the estimation of functional antibody affinity
-
Goldblatt, D., L. van Etten, F. J. van Milligen, R. C. Aalberse, and M. W. Turner. 1993. The role of pH in modified ELISA procedures used for the estimation of functional antibody affinity. J. Immunol. Methods 166:281-285.
-
(1993)
J. Immunol. Methods
, vol.166
, pp. 281-285
-
-
Goldblatt, D.1
Van Etten, L.2
Van Milligen, F.J.3
Aalberse, R.C.4
Turner, M.W.5
-
17
-
-
17344361836
-
Antibody avidity as a surrogate marker of successful priming by Haemophilus influenzae type b conjugate vaccines following infant immunization
-
Goldblatt, D., A. R. Vaz, and E. Miller. 1998. Antibody avidity as a surrogate marker of successful priming by Haemophilus influenzae type b conjugate vaccines following infant immunization. J. Infect. Dis. 177:1112-1115.
-
(1998)
J. Infect. Dis.
, vol.177
, pp. 1112-1115
-
-
Goldblatt, D.1
Vaz, A.R.2
Miller, E.3
-
18
-
-
0031932299
-
Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation
-
Gonzalez-Fernandez, A., and C. Milstein. 1998. Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation. Immunology 93:149-153.
-
(1998)
Immunology
, vol.93
, pp. 149-153
-
-
Gonzalez-Fernandez, A.1
Milstein, C.2
-
19
-
-
0032931928
-
The first dose of a Haemophilus influenzae type b conjugate vaccine reactivates memory B cells: Evidence for extensive clonal selection, intraclonal affinity maturation, and multiple isotype switches to IgA2
-
Hougs, L., L. Juul, H. J. Ditzel, C. Heilmann, A. Svejgaard, and T. Barington. 1999. The first dose of a Haemophilus influenzae type b conjugate vaccine reactivates memory B cells: evidence for extensive clonal selection, intraclonal affinity maturation, and multiple isotype switches to IgA2. J. Immunol. 162:224-237.
-
(1999)
J. Immunol.
, vol.162
, pp. 224-237
-
-
Hougs, L.1
Juul, L.2
Ditzel, H.J.3
Heilmann, C.4
Svejgaard, A.5
Barington, T.6
-
20
-
-
0032953203
-
Structural requirements of the major protective antibody to Haemophilus influenzae type b
-
Hougs, L., L. Juul, A. Svejgaard, and T. Barington. 1999. Structural requirements of the major protective antibody to Haemophilus influenzae type b. Infect. Immun. 67:2503-2514.
-
(1999)
Infect. Immun.
, vol.67
, pp. 2503-2514
-
-
Hougs, L.1
Juul, L.2
Svejgaard, A.3
Barington, T.4
-
21
-
-
0032434029
-
Use of highly encapsulated Streptococcus pneumoniae strains in a flow-cytometric assay for assessment of the phagocytic capacity of serotype-specific antibodies
-
Jansen, W. T., J. Gootjes, M. Zelle, D. V. Madore, J. Verhoef, H. Snippe, and A. F. Verheul. 1998. Use of highly encapsulated Streptococcus pneumoniae strains in a flow-cytometric assay for assessment of the phagocytic capacity of serotype-specific antibodies. Clin. Diagn. Lab. Immunol. 5:703-710.
-
(1998)
Clin. Diagn. Lab. Immunol.
, vol.5
, pp. 703-710
-
-
Jansen, W.T.1
Gootjes, J.2
Zelle, M.3
Madore, D.V.4
Verhoef, J.5
Snippe, H.6
Verheul, A.F.7
-
22
-
-
0034566064
-
Preparation of human-mouse heterohybridomas against an immunising antigen
-
Jessup, C. F., H. Baxendale, D. Goldblatt, and H. Zola. 2000. Preparation of human-mouse heterohybridomas against an immunising antigen. J. Immunol. Methods 246:187-202.
-
(2000)
J. Immunol. Methods
, vol.246
, pp. 187-202
-
-
Jessup, C.F.1
Baxendale, H.2
Goldblatt, D.3
Zola, H.4
-
23
-
-
0033016586
-
Correlation of opsonophagocytosis and passive protection assays using human anticapsular antibodies in an infant mouse model of bacteremia for Streptococcus pneumoniae
-
Johnson, S. E., L. Rubin, S. S. Romero, J. K. Dykes, L. B. Pais, A. Rizvi, E. Ades, and G. M. Carlone. 1999. Correlation of opsonophagocytosis and passive protection assays using human anticapsular antibodies in an infant mouse model of bacteremia for Streptococcus pneumoniae. J. Infect. Dis. 180:133-140.
-
(1999)
J. Infect. Dis.
, vol.180
, pp. 133-140
-
-
Johnson, S.E.1
Rubin, L.2
Romero, S.S.3
Dykes, J.K.4
Pais, L.B.5
Rizvi, A.6
Ades, E.7
Carlone, G.M.8
-
24
-
-
14844358870
-
Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type B polysaccharide-protein conjugates
-
Lucas, A. H., and D. M. Granoff. 1995. Functional differences in idiotypically defined IgG1 anti-polysaccharide antibodies elicited by vaccination with Haemophilus influenzae type B polysaccharide-protein conjugates. J. Immunol. 154:4195-4202.
-
(1995)
J. Immunol.
, vol.154
, pp. 4195-4202
-
-
Lucas, A.H.1
Granoff, D.M.2
-
25
-
-
0030729224
-
Oligoclonality of serum immunoglobulin G antibody responses to Streptococcus pneumoniae capsular polysaccharide serotypes 6B and 23F
-
Lucas, A. H., D. M. Granoff, R. E. Mandrell, C. C. Connolly, A. S. Shan, and D. C. Powers. 1997. Oligoclonality of serum immunoglobulin G antibody responses to Streptococcus pneumoniae capsular polysaccharide serotypes 6B and 23F. Infect. Immun. 65:5103-5109.
-
(1997)
Infect. Immun.
, vol.65
, pp. 5103-5109
-
-
Lucas, A.H.1
Granoff, D.M.2
Mandrell, R.E.3
Connolly, C.C.4
Shan, A.S.5
Powers, D.C.6
-
26
-
-
0032193211
-
Role of kappa II-A2 light chain CDR-3 junctional residues in human antibody binding to the Haemophilus influenzae type b polysaccharide
-
Lucas, A. H., K. D. Moulton, and D. C. Reason. 1998. Role of kappa II-A2 light chain CDR-3 junctional residues in human antibody binding to the Haemophilus influenzae type b polysaccharide. J. Immunol. 161:3776-3780.
-
(1998)
J. Immunol.
, vol.161
, pp. 3776-3780
-
-
Lucas, A.H.1
Moulton, K.D.2
Reason, D.C.3
-
27
-
-
0035145467
-
Combinatorial library cloning of human antibodies to Streptococcus pneumoniae capsular polysaccharides: Variable region primary structures and evidence for somatic mutation of Fab fragments specific for capsular serotypes 6B and 23F
-
Lucas, A. H., K. D. Moulton, V. R. Tang, and D. C. Reason. 2001. Combinatorial library cloning of human antibodies to Streptococcus pneumoniae capsular polysaccharides: variable region primary structures and evidence for somatic mutation of Fab fragments specific for capsular serotypes 6B and 23F. Infect. Immun. 69:853-864.
-
(2001)
Infect. Immun.
, vol.69
, pp. 853-864
-
-
Lucas, A.H.1
Moulton, K.D.2
Tang, V.R.3
Reason, D.C.4
-
28
-
-
0030757999
-
Correlation between the avidity of mouse-human chimeric IgG subclass monoclonal antibodies measured by solid-phase elution ELISA and biospecific interaction analysis (BIA)
-
McCloskey, N., M. W. Turner, and T. D. Goldblatt. 1997. Correlation between the avidity of mouse-human chimeric IgG subclass monoclonal antibodies measured by solid-phase elution ELISA and biospecific interaction analysis (BIA). J. Immunol. Methods 205:67-72.
-
(1997)
J. Immunol. Methods
, vol.205
, pp. 67-72
-
-
McCloskey, N.1
Turner, M.W.2
Goldblatt, T.D.3
-
29
-
-
0029895302
-
Human constant regions influence the antibody binding characteristics of mouse-human chimeric IgG subclasses
-
McCloskey, N., M. W. Turner, P. Steffner, R. Owens, and D. Goldblatt. 1996. Human constant regions influence the antibody binding characteristics of mouse-human chimeric IgG subclasses. Immunology 88:169-173.
-
(1996)
Immunology
, vol.88
, pp. 169-173
-
-
McCloskey, N.1
Turner, M.W.2
Steffner, P.3
Owens, R.4
Goldblatt, D.5
-
30
-
-
0034536631
-
Can isotype switch modulate antigen-binding affinity and influence clonal selection?
-
Pritsch, O., C. Magnac, G. Dumas, J. P. Bouvet, P. Alzari, and G. Dighiero. 2000. Can isotype switch modulate antigen-binding affinity and influence clonal selection? Eur. J. Immunol. 30:3387-3395.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 3387-3395
-
-
Pritsch, O.1
Magnac, C.2
Dumas, G.3
Bouvet, J.P.4
Alzari, P.5
Dighiero, G.6
-
31
-
-
0032776804
-
Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity
-
Romero, S. S., D. M. Musher, M. S. Cetron, L. B. Pais, J. E. Groover, A. E. Fiore, B. D. Plikaytis, and G. M. Carlone. 1999. Reduction in functional antibody activity against Streptococcus pneumoniae in vaccinated elderly individuals highly correlates with decreased IgG antibody avidity. Clin. Infect. Dis. 29:281-288.
-
(1999)
Clin. Infect. Dis.
, vol.29
, pp. 281-288
-
-
Romero, S.S.1
Musher, D.M.2
Cetron, M.S.3
Pais, L.B.4
Groover, J.E.5
Fiore, A.E.6
Plikaytis, B.D.7
Carlone, G.M.8
-
32
-
-
0034782205
-
The response in old mice: Positive and negative immune memory after priming in early age
-
Sanchez, M., K. Lindroth, E. Sverremark, F. A. Gonzalez, and C. Fernandez. 2001. The response in old mice: positive and negative immune memory after priming in early age. Int. Immunol. 13:1213-1221.
-
(2001)
Int. Immunol.
, vol.13
, pp. 1213-1221
-
-
Sanchez, M.1
Lindroth, K.2
Sverremark, E.3
Gonzalez, F.A.4
Fernandez, C.5
-
33
-
-
0033012615
-
Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B
-
Sun, Y., M. K. Park, J. Kim, B. Diamond, A. Solomon, and M. H. Nahm. 1999. Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B. Infect. Immun. 67:1172-1179.
-
(1999)
Infect. Immun.
, vol.67
, pp. 1172-1179
-
-
Sun, Y.1
Park, M.K.2
Kim, J.3
Diamond, B.4
Solomon, A.5
Nahm, M.H.6
-
34
-
-
0032903986
-
Avidity as a determinant of the protective efficacy of human antibodies to pneumococcal capsular polysaccharides
-
Usinger, W. R., and A. H. Lucas. 1999. Avidity as a determinant of the protective efficacy of human antibodies to pneumococcal capsular polysaccharides. Infect. Immun. 67:2366-2370.
-
(1999)
Infect. Immun.
, vol.67
, pp. 2366-2370
-
-
Usinger, W.R.1
Lucas, A.H.2
-
35
-
-
0033711628
-
Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities
-
Xu, J. L., and M. M. Davis. 2000. Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities. Immunity 13:37-45.
-
(2000)
Immunity
, vol.13
, pp. 37-45
-
-
Xu, J.L.1
Davis, M.M.2
-
36
-
-
0036073282
-
Recurrent variable region gene usage and somatic mutation in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae type 23F
-
Zhou, J., K. R. Lottenbach, S. J. Barenkamp, A. H. Lucas, and D. C. Reason. 2002. Recurrent variable region gene usage and somatic mutation in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae type 23F. Infect. Immun. 70:4083-4091.
-
(2002)
Infect. Immun.
, vol.70
, pp. 4083-4091
-
-
Zhou, J.1
Lottenbach, K.R.2
Barenkamp, S.J.3
Lucas, A.H.4
Reason, D.C.5
-
37
-
-
2542556728
-
Somatic hypermutation and diverse immunoglobulin gene usage in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae type 6B
-
Zhou, J., K. R. Lottenbach, S. J. Barenkamp, and D. C. Reason. 2004. Somatic hypermutation and diverse immunoglobulin gene usage in the human antibody response to the capsular polysaccharide of Streptococcus pneumoniae type 6B. Infect. Immun. 72:3505-3514.
-
(2004)
Infect. Immun.
, vol.72
, pp. 3505-3514
-
-
Zhou, J.1
Lottenbach, K.R.2
Barenkamp, S.J.3
Reason, D.C.4
|