메뉴 건너뛰기




Volumn 267, Issue 3, 1997, Pages 684-695

Mapping the protein surface of human immunodeficiency virus type 1 gp120 using human monoclonal antibodies from phage display libraries

Author keywords

Combinatorial libraries; Epitope mapping; gp120 topology; HIV infection; Human antibody repertoires

Indexed keywords

GLYCOPROTEIN GP 120; HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; RECOMBINANT PROTEIN; VIRUS PROTEIN;

EID: 0031552347     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1997.0912     Document Type: Article
Times cited : (50)

References (45)
  • 1
    • 0025838021 scopus 로고
    • Assembly of combinatorial antibody libraries on phage surfaces: The gene III site
    • Barbas C. F., Kang A. S., Lerner R. A., Benkovic S. J. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl Acad. Sci. USA. 88:1991;7978-7982.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 7978-7982
    • Barbas, C.F.1    Kang, A.S.2    Lerner, R.A.3    Benkovic, S.J.4
  • 4
    • 0029957873 scopus 로고    scopus 로고
    • Human antibody responses to HIV-1 gp41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding
    • Binley J. M., Ditzel H. J., Barbas C. F., Sullivan N., Sodroski J., Parren P. W. H. I., Burton D. R. Human antibody responses to HIV-1 gp41 cloned in phage display libraries suggest three major epitopes are recognized and give evidence for conserved antibody motifs in antigen binding. AIDS Res. Hum. Retrovir. 12:1996;911-924.
    • (1996) AIDS Res. Hum. Retrovir. , vol.12 , pp. 911-924
    • Binley, J.M.1    Ditzel, H.J.2    Barbas, C.F.3    Sullivan, N.4    Sodroski, J.5    Parren, P.W.H.I.6    Burton, D.R.7
  • 5
    • 0028672525 scopus 로고
    • Human antibodies from combinatorial libraries
    • Burton D. R., Barbas C. F. Human antibodies from combinatorial libraries. Advan. Immunol. 57:1994;191-280.
    • (1994) Advan. Immunol. , vol.57 , pp. 191-280
    • Burton, D.R.1    Barbas, C.F.2
  • 6
    • 0025838698 scopus 로고
    • A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals
    • Burton D. R., Barbas C. F., Persson M. A., Koenig S., Chanock R. M., Lerner R. A. A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals. Proc. Natl Acad. Sci. USA. 88:1991;10134-10137.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 10134-10137
    • Burton, D.R.1    Barbas, C.F.2    Persson, M.A.3    Koenig, S.4    Chanock, R.M.5    Lerner, R.A.6
  • 7
    • 17144456021 scopus 로고    scopus 로고
    • The antibody response in HIV-1 infection
    • Burton D. R., Montefiori D. C. The antibody response in HIV-1 infection. AIDS. 1997.
    • (1997) AIDS
    • Burton, D.R.1    Montefiori, D.C.2
  • 10
    • 0028334944 scopus 로고
    • The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection
    • Ditzel H. J., Barbas S. M., Barbas C. F., Burton D. R. The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection. Proc. Natl Acad. Sci. USA. 91:1994;3710-3714.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 3710-3714
    • Ditzel, H.J.1    Barbas, S.M.2    Barbas, C.F.3    Burton, D.R.4
  • 11
    • 0028831142 scopus 로고
    • Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure
    • Ditzel H. J., Binley J. M., Moore J. P., Sodroski J., Sullivan N., Sawyer L. S. W., Hendry R. M., Yang W.-P., Barbas C. F., Burton D. R. Neutralizing recombinant human antibodies to a conformational V2- and CD4-binding site-sensitive epitope of HIV-1 gp120 isolated by using an epitope-masking procedure. J. Immunol. 154:1995;895-908.
    • (1995) J. Immunol. , vol.154 , pp. 895-908
    • Ditzel, H.J.1    Binley, J.M.2    Moore, J.P.3    Sodroski, J.4    Sullivan, N.5    Sawyer, L.S.W.6    Hendry, R.M.7    Yang, W.-P.8    Barbas, C.F.9    Burton, D.R.10
  • 12
    • 0028355456 scopus 로고
    • Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities
    • Earl P. L., Broder C. C., Long D., Lee S. A., Peterson J., Chakrabarti S., Doms R. W., Moss B. Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities. J. Virol. 68:1994;3015-3026.
    • (1994) J. Virol. , vol.68 , pp. 3015-3026
    • Earl, P.L.1    Broder, C.C.2    Long, D.3    Lee, S.A.4    Peterson, J.5    Chakrabarti, S.6    Doms, R.W.7    Moss, B.8
  • 13
    • 0026595148 scopus 로고
    • Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120
    • Fung M. S. C., Sun C. R. Y., Gordon W. L., Liou R.-S., Chang T. W., Sun W. N. C., Daar E. S., Ho D. D. Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120. J. Virol. 66:1992;848-840.
    • (1992) J. Virol. , vol.66 , pp. 848-840
    • Fung, M.S.C.1    Sun, C.R.Y.2    Gordon, W.L.3    Liou, R.-S.4    Chang, T.W.5    Sun, W.N.C.6    Daar, E.S.7    Ho, D.D.8
  • 15
    • 0025074650 scopus 로고
    • Application of a rapid microplaque assay for determination of human immunodeficiency virus neutralizing antibody titers
    • Hanson C. V., Crawford-Miksza L., Sheppard H. W. Application of a rapid microplaque assay for determination of human immunodeficiency virus neutralizing antibody titers. J. Clin. Microbiol. 28:1990;2030-2034.
    • (1990) J. Clin. Microbiol. , vol.28 , pp. 2030-2034
    • Hanson, C.V.1    Crawford-Miksza, L.2    Sheppard, H.W.3
  • 16
    • 0025268873 scopus 로고
    • Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants
    • Helseth E., Kowalski M., Gabuzda D., Olshevsky U., Haseltine W., Sodroski J. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants. J. Virol. 64:1990;2416-2420.
    • (1990) J. Virol. , vol.64 , pp. 2416-2420
    • Helseth, E.1    Kowalski, M.2    Gabuzda, D.3    Olshevsky, U.4    Haseltine, W.5    Sodroski, J.6
  • 17
    • 0025950326 scopus 로고
    • Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibody
    • Ho D. D., Fung M. S. C., Cao Y. Z., Li X. L., Sun C., Chang T. W., Sun N. C. Another discontinuous epitope on glycoprotein gp120 that is important in human immunodeficiency virus type 1 neutralization is identified by a monoclonal antibody. Proc. Natl Acad. Sci. USA. 88:1991;8949-8952.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 8949-8952
    • Ho, D.D.1    Fung, M.S.C.2    Cao, Y.Z.3    Li, X.L.4    Sun, C.5    Chang, T.W.6    Sun, N.C.7
  • 19
    • 0028111660 scopus 로고
    • Immunization with a soluble CD4-gp120 complex preferentially induces neutralizing anti-human immunodeficiency virus type 1 antibodies directed to conformation-dependent epitopes of gp120
    • Kang C.-Y., Hariharan K., Nara P. L., Sodroski J., Moore J. P. Immunization with a soluble CD4-gp120 complex preferentially induces neutralizing anti-human immunodeficiency virus type 1 antibodies directed to conformation-dependent epitopes of gp120. J. Virol. 68:1994;5854-5862.
    • (1994) J. Virol. , vol.68 , pp. 5854-5862
    • Kang, C.-Y.1    Hariharan, K.2    Nara, P.L.3    Sodroski, J.4    Moore, J.P.5
  • 20
    • 0025876152 scopus 로고
    • Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system
    • Karlsson R. A., Michaelsson A., Mattsson L. Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. J. Immunol. Methods. 145:1991;229-240.
    • (1991) J. Immunol. Methods , vol.145 , pp. 229-240
    • Karlsson, R.A.1    Michaelsson, A.2    Mattsson, L.3
  • 21
    • 0028097964 scopus 로고
    • Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains
    • Kayman S. C., Wu Z., Revesz K., Chen H., Kopelman R., Pinter A. Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains. J. Virol. 68:1994;400-410.
    • (1994) J. Virol. , vol.68 , pp. 400-410
    • Kayman, S.C.1    Wu, Z.2    Revesz, K.3    Chen, H.4    Kopelman, R.5    Pinter, A.6
  • 22
    • 0026537412 scopus 로고
    • Variant-specific monoclonal and group-specific polyclonal human immunodeficiency virus type 1 neutralizing antibodies raised with synthetic peptides from gp120 third variable domain
    • Laman J. D., Schellekens M. M., Abacioglu Y. F., Lewis G. K., Tersmette M., Fouchier R. A. M., Langedijk J. P. M., Claassen E., Boersma W. J. A. Variant-specific monoclonal and group-specific polyclonal human immunodeficiency virus type 1 neutralizing antibodies raised with synthetic peptides from gp120 third variable domain. J. Virol. 66:1992;1823-1831.
    • (1992) J. Virol. , vol.66 , pp. 1823-1831
    • Laman, J.D.1    Schellekens, M.M.2    Abacioglu, Y.F.3    Lewis, G.K.4    Tersmette, M.5    Fouchier, R.A.M.6    Langedijk, J.P.M.7    Claassen, E.8    Boersma, W.J.A.9
  • 23
    • 0023107134 scopus 로고
    • Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: Prediction of antigenic epitopes in conserved and variable regions
    • Modrow S., Hahn B. H., Shaw G. M., Gallo R. C., Wong-Staal F., Wolf H. Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions. J. Virol. 61:1987;570-578.
    • (1987) J. Virol. , vol.61 , pp. 570-578
    • Modrow, S.1    Hahn, B.H.2    Shaw, G.M.3    Gallo, R.C.4    Wong-Staal, F.5    Wolf, H.6
  • 24
    • 0027397052 scopus 로고
    • Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans
    • Moore J. P., Ho D. D. Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans. J. Virol. 67:1993;863-875.
    • (1993) J. Virol. , vol.67 , pp. 863-875
    • Moore, J.P.1    Ho, D.D.2
  • 25
    • 0005000433 scopus 로고
    • HIV-1 neutralization: The consequences of viral adaptation to growth on transformed T cells
    • Moore J. P., Ho D. D. HIV-1 neutralization: the consequences of viral adaptation to growth on transformed T cells. AIDS. 9(suppl A):1995;S117-S136.
    • (1995) AIDS , vol.9
    • Moore, J.P.1    Ho, D.D.2
  • 26
    • 0030043169 scopus 로고    scopus 로고
    • Antibody cross-competition analysis of the human immundeficiency virus type 1 gp120 exterior envelope glycoprotein
    • Moore J. P., Sodroski J. Antibody cross-competition analysis of the human immundeficiency virus type 1 gp120 exterior envelope glycoprotein. J. Virol. 70:1996;1863-1872.
    • (1996) J. Virol. , vol.70 , pp. 1863-1872
    • Moore, J.P.1    Sodroski, J.2
  • 29
    • 0028107685 scopus 로고
    • Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies
    • Moore J. P., Sattentau Q. J., Wyatt R., Sodroski J. Probing the structure of the human immunodeficiency virus surface glycoprotein gp120 with a panel of monoclonal antibodies. J. Virol. 68:1994a;469-484.
    • (1994) J. Virol. , vol.68 , pp. 469-484
    • Moore, J.P.1    Sattentau, Q.J.2    Wyatt, R.3    Sodroski, J.4
  • 30
    • 0028034993 scopus 로고
    • Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1
    • Moore J. P., Willey R. L., Lewis G. K., Robinson J., Sodroski J. Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1. J. Virol. 68:1994b;6836-6847.
    • (1994) J. Virol. , vol.68 , pp. 6836-6847
    • Moore, J.P.1    Willey, R.L.2    Lewis, G.K.3    Robinson, J.4    Sodroski, J.5
  • 31
    • 0028917784 scopus 로고
    • Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120
    • Moore J. P., Cao Y., Qing L., Sattentau Q. J., Pyati J., Koduri R., Robinson J., Barbas C. F., Burton D. R., Ho D. D. Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120. J. Virol. 69:1995;101-109.
    • (1995) J. Virol. , vol.69 , pp. 101-109
    • Moore, J.P.1    Cao, Y.2    Qing, L.3    Sattentau, Q.J.4    Pyati, J.5    Koduri, R.6    Robinson, J.7    Barbas, C.F.8    Burton, D.R.9    Ho, D.D.10
  • 32
    • 0023553078 scopus 로고
    • Simple, rapid, quantitative syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody
    • Nara P. L., Hatch W. C., Dunlop N. M., Robey W. G., Arthur L. O., Gonda M. A., Fischinger P. J. Simple, rapid, quantitative syncytium-forming microassay for the detection of human immunodeficiency virus neutralizing antibody. AIDS Res. Hum. Retrovir. 3:1987;283-302.
    • (1987) AIDS Res. Hum. Retrovir. , vol.3 , pp. 283-302
    • Nara, P.L.1    Hatch, W.C.2    Dunlop, N.M.3    Robey, W.G.4    Arthur, L.O.5    Gonda, M.A.6    Fischinger, P.J.7
  • 33
    • 0029861453 scopus 로고    scopus 로고
    • In vitro antigen challenge of human antibody libraries for vaccine evaluation: The human immunodeficiency virus type I envelope
    • Parren P. W. H. I., Fisicaro P., Labrijn A. F., Binley J. M., Yang W. P., Ditzel H. J., Barbas C. F., Burton D. R. In vitro antigen challenge of human antibody libraries for vaccine evaluation: the human immunodeficiency virus type I envelope. J. Virol. 70:1996;9046-9050.
    • (1996) J. Virol. , vol.70 , pp. 9046-9050
    • Parren, P.W.H.I.1    Fisicaro, P.2    Labrijn, A.F.3    Binley, J.M.4    Yang, W.P.5    Ditzel, H.J.6    Barbas, C.F.7    Burton, D.R.8
  • 34
    • 0026057989 scopus 로고
    • Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning
    • Persson M. A., Caothien R. H., Burton D. R. Generation of diverse high-affinity human monoclonal antibodies by repertoire cloning. Proc. Natl Acad. Sci. USA. 88:1991;2432-2436.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 2432-2436
    • Persson, M.A.1    Caothien, R.H.2    Burton, D.R.3
  • 36
    • 0028291731 scopus 로고
    • Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1
    • Roben P., Moore J. P., Thali M., Sodroski J., Barbas C. F., Burton D. R. Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1. J. Virol. 68:1994;4821-4828.
    • (1994) J. Virol. , vol.68 , pp. 4821-4828
    • Roben, P.1    Moore, J.P.2    Thali, M.3    Sodroski, J.4    Barbas, C.F.5    Burton, D.R.6
  • 37
    • 0028999803 scopus 로고
    • Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer
    • Sattentau Q. J., Moore J. P. Human immunodeficiency virus type 1 neutralization is determined by epitope exposure on the gp120 oligomer. J. Exp. Med. 182:1995;185-196.
    • (1995) J. Exp. Med. , vol.182 , pp. 185-196
    • Sattentau, Q.J.1    Moore, J.P.2
  • 39
    • 0022459886 scopus 로고
    • Identification and characterization of conserved and variable regions in the envelope gene of HTLVIII/LAV the retrovirus of AIDS
    • Starcich B. R., Hahn B. H., Shaw G. M., McNeal P. D., Modrow, Wolf H., Parks W. P., Josephs F., Gallo R. C., Wong-Staal F. Identification and characterization of conserved and variable regions in the envelope gene of HTLVIII/LAV the retrovirus of AIDS. Cell. 45:1986;637-648.
    • (1986) Cell , vol.45 , pp. 637-648
    • Starcich, B.R.1    Hahn, B.H.2    Shaw, G.M.3    McNeal, P.D.4    Modrow5    Wolf, H.6    Parks, W.P.7    Josephs, F.8    Gallo, R.C.9    Wong-Staal, F.10
  • 40
    • 0027204667 scopus 로고
    • Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody
    • Sullivan N., Thali M., Furman C., Ho D. D., Sodroski J. Effect of amino acid changes in the V1/V2 region of the human immunodeficiency virus type 1 gp120 glycoprotein on subunit association, syncytium formation, and recognition by a neutralizing antibody. J. Virol. 67:1993;3674-3679.
    • (1993) J. Virol. , vol.67 , pp. 3674-3679
    • Sullivan, N.1    Thali, M.2    Furman, C.3    Ho, D.D.4    Sodroski, J.5
  • 41
    • 0027256814 scopus 로고
    • Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding
    • Thali M., Moore J. P., Furman C., Charles M., Ho D. D., Robinson J., Sodroski J. Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. J. Virol. 67:1993;3978-3988.
    • (1993) J. Virol. , vol.67 , pp. 3978-3988
    • Thali, M.1    Moore, J.P.2    Furman, C.3    Charles, M.4    Ho, D.D.5    Robinson, J.6    Sodroski, J.7
  • 45
    • 0026454213 scopus 로고
    • Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region
    • Wyatt R., Thali M., Tilley S., Pinter A., Posner M., Ho D., Robinson J., Sodroski J. Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region. J. Virol. 66:1992;6997-7004.
    • (1992) J. Virol. , vol.66 , pp. 6997-7004
    • Wyatt, R.1    Thali, M.2    Tilley, S.3    Pinter, A.4    Posner, M.5    Ho, D.6    Robinson, J.7    Sodroski, J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.