Cigarette smoke attenuation of poly I:C-induced innate antiviral responses in human PBMC is mainly due to inhibition of IFN-β production

Molecular Immunology

Volumn 46, Issue 5, 2009, Pages 821-829

  Mian, M Firoz ^a   Stämpfli, Martin R ^a,b   Mossman, Karen L ^a,b   Ashkar, Ali A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Anti viral immunity; Cigarette smoke; IRF 3; PBMC; STAT1; Type 1 IFN

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CIGARETTE SMOKE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; POLYINOSINIC POLYCYTIDYLIC ACID; STAT1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CELL STIMULATION; CIGARETTE SMOKING; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFECTION RESISTANCE; INHIBITION KINETICS; INNATE IMMUNITY; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SHAM PROCEDURE; SIGNAL TRANSDUCTION; SMOKING; SPLEEN CELL; VESICULAR STOMATITIS VIRUS; VIRUS INFECTION;

ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; FEMALE; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MICE; MICE, KNOCKOUT; NF-KAPPA B; POLY I-C; SMOKING; STAT1 TRANSCRIPTION FACTOR; VERO CELLS; VESICULOVIRUS;

MUS;

EID: 59249099648     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.09.007     Document Type: Article

References (51)

1. Aderem A., and Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature 406 (2000) 782-787
2. Akira S., Takeda K., and Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2 (2001) 675-680
3. Alexopoulou L., Holt A.C., Medzhitov R., and Flavell R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413 (2001) 732-738
4. Aramburu J., Azzoni L., Rao A., and Perussia B. Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding. J. Exp. Med. 182 (1995) 801-810
5. Arcavi L., and Benowitz N.L. Cigarette smoking and infection. Arch. Intern. Med. 164 (2004) 2206-2216
6. Aronson M.D., Weiss S.T., Ben R.L., and Komaroff A.L. Association between cigarette smoking and acute respiratory tract illness in young adults. JAMA 248 (1982) 181-183
7. Ashkar A.A., and Rosenthal K.L. Interleukin-15 and natural killer and NKT cells play a critical role in innate protection against genital herpes simplex virus type 2 infection. J. Virol. 77 (2003) 10168-10171
8. Ashkar A.A., Yao X.D., Gill N., Sajic D., Patrick A.J., and Rosenthal K.L. Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA. J. Infect. Dis. 190 (2004) 1841-1849
9. Baccala R., Hoebe K., Kono D.H., Beutler B., and Theofilopoulos A.N. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity. Nat. Med. 13 (2007) 543-551
10. Barton G.M., and Medzhitov R. Toll-like receptor signaling pathways. Science 300 (2003) 1524-1525
11. Bauer C.M., Dewitte-Orr S.J., Hornby K.R., Zavitz C.C., Lichty B.D., Stampfli M.R., and Mossman K.L. Cigarette smoke suppresses type I interferon-mediated antiviral immunity in lung fibroblast and epithelial cells. J. Interferon. Cytokine Res. 28 (2008) 167-179
12. Bernhard D., Huck C.W., Jakschitz T., Pfister G., Henderson B., Bonn G.K., and Wick G. Development and evaluation of an in vitro model for the analysis of cigarette smoke effects on cultured cells and tissues. J. Pharmacol. Toxicol. Methods 50 (2004) 45-51
13. Biron C.A. Role of early cytokines, including alpha and beta interferons (IFN-alpha/beta), in innate and adaptive immune responses to viral infections. Semin. Immunol. 10 (1998) 383-390
14. Boehme K.W., and Compton T. Innate sensing of viruses by Toll-like receptors. J. Virol. 78 (2004) 7867-7873
15. Burns D.N., Landesman S., Muenz L.R., Nugent R.P., Goedert J.J., Minkoff H., Walsh J.H., Mendez H., Rubinstein A., and Willoughby A. Cigarette smoking, premature rupture of membranes, and vertical transmission of HIV-1 among women with low CD4+levels. J. Acquir. Immune Defic. Syndr. 7 (1994) 718-726
16. Collins S.E., Noyce R.S., and Mossman K.L. Innate cellular response to virus particle entry requires IRF3 but not virus replication. J. Virol. 78 (2004) 1706-1717
17. Crothers K., Griffith T.A., McGinnis K.A., Rodriguez-Barradas M.C., Leaf D.A., Weissman S., Gibert C.L., Butt A.A., and Justice A.C. The impact of cigarette smoking on mortality, quality of life, and comorbid illness among HIV-positive veterans. J. Gen. Intern. Med. 20 (2005) 1142-1145
18. Demirjian L., Abboud R.T., Li H., and Duronio V. Acute effect of cigarette smoke on TNF-alpha release by macrophages mediated through the erk1/2 pathway. Biochim. Biophys. Acta 1762 (2006) 592-597
19. Doyle S.E., O'Connell R., Vaidya S.A., Chow E.K., Yee K., and Cheng G. Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4. J. Immunol. 170 (2003) 3565-3571
20. Gaschler G.J., Zavitz C.C., Bauer C.M., Skrtic M., Lindahl M., Robbins C.S., Chen B., and Stampfli M.R. Cigarette smoke exposure attenuates cytokine production by mouse alveolar macrophages. Am. J. Respir. Cell Mol. Biol. (2007)
21. Gill N., Deacon P.M., Lichty B., Mossman K.L., and Ashkar A.A. Induction of innate immunity against herpes simplex virus type 2 infection via local delivery of Toll-like receptor ligands correlates with beta interferon production. J. Virol. 80 (2006) 9943-9950
22. Goriely S., Molle C., Nguyen M., Albarani V., Haddou N.O., Lin R., De Wit D., Flamand V., Willems F., and Goldman M. Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood 107 (2006) 1078-1084
23. Honda K., Takaoka A., and Taniguchi T. Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25 (2006) 349-360
24. Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., and Taniguchi T. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 434 (2005) 772-777
25. Iwasaki A., and Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5 (2004) 987-995
26. Kawai T., and Akira S. TLR signaling. Cell Death Differ 13 (2006) 816-825
27. Lauzon N.M., Mian F., MacKenzie R., and Ashkar A.A. The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell Immunol. 241 (2006) 102-112
28. Lu L.M., Zavitz C.C., Chen B., Kianpour S., Wan Y., and Stampfli M.R. Cigarette smoke impairs NK cell-dependent tumor immune surveillance. J. Immunol. 178 (2007) 936-943
29. McCrea K.A., Ensor J.E., Nall K., Bleecker E.R., and Hasday J.D. Altered cytokine regulation in the lungs of cigarette smokers. Am. J. Respir. Crit. Care Med. 150 (1994) 696-703
30. Medzhitov R., and Janeway Jr. C.A. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91 (1997) 295-298
31. Meylan E., and Tschopp J. Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol. Cell 22 (2006) 561-569
32. Mian M.F., Lauzon N.M., Stampfli M.R., Mossman K.L., and Ashkar A.A. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke. J. Leukoc. Biol. 83 (2008) 774-784
33. Nicholson K.G., Kent J., and Hammersley V. Influenza A among community-dwelling elderly persons in Leicestershire during winter 1993-4; cigarette smoking as a risk factor and the efficacy of influenza vaccination. Epidemiol. Infect. 123 (1999) 103-108
34. Paladino P., Cummings D.T., Noyce R.S., and Mossman K.L. The IFN-independent response to virus particle entry provides a first line of antiviral defense that is independent of TLRs and retinoic acid-inducible gene I. J. Immunol. 177 (2006) 8008-8016
35. Platanias L.C. Mechanisms of type-I- and type-II-interferon-mediated signalling. Nat. Rev. Immunol. 5 (2005) 375-386
36. Robbins C.S., Dawe D.E., Goncharova S.I., Pouladi M.A., Drannik A.G., Swirski F.K., Cox G., and Stampfli M.R. Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am. J. Respir. Cell Mol. Biol. 30 (2004) 202-211
37. Sato M., Suemori H., Hata N., Asagiri M., Ogasawara K., Nakao K., Nakaya T., Katsuki M., Noguchi S., Tanaka N., and Taniguchi T. Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction. Immunity 13 (2000) 539-548
38. Schaefer T.M., Fahey J.V., Wright J.A., and Wira C.R. Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C). J. Immunol. 174 (2005) 992-1002
39. Schmidt K.N., Leung B., Kwong M., Zarember K.A., Satyal S., Navas T.A., Wang F., and Godowski P.J. APC-independent activation of NK cells by the Toll-like receptor 3 agonist double-stranded RNA. J. Immunol. 172 (2004) 138-143
40. Sonnenfeld G., and Hudgens R.W. Effect of sidestream and mainstream smoke exposure on in vitro interferon-alpha/beta production by L-929 cells. Cancer Res. 46 (1986) 2779-2783
41. Sopori M. Effects of cigarette smoke on the immune system. Nat. Rev. Immunol. 2 (2002) 372-377
42. Stark G.R., Kerr I.M., Williams B.R., Silverman R.H., and Schreiber R.D. How cells respond to interferons. Annu. Rev. Biochem. 67 (1998) 227-264
43. Takaoka A., and Taniguchi T. New aspects of IFN-alpha/beta signalling in immunity, oncogenesis and bone metabolism. Cancer Sci. 94 (2003) 405-411
44. Taniguchi T., Ogasawara K., Takaoka A., and Tanaka N. IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol. 19 (2001) 623-655
45. Tato C.M., Mason N., Artis D., Shapira S., Caamano J.C., Bream J.H., Liou H.C., and Hunter C.A. Opposing roles of NF-kappaB family members in the regulation of NK cell proliferation and production of IFN-gamma. Int. Immunol. 18 (2006) 505-513
46. Theofilopoulos A.N., Baccala R., Beutler B., and Kono D.H. Type I interferons (alpha/beta) in immunity and autoimmunity. Annu. Rev. Immunol. 23 (2005) 307-336
47. Tissari J., Siren J., Meri S., Julkunen I., and Matikainen S. IFN-alpha enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J. Immunol. 174 (2005) 4289-4294
48. Underhill D.M., and Ozinsky A. Toll-like receptors: key mediators of microbe detection. Curr. Opin. Immunol. 14 (2002) 103-110
49. Walker W., Aste-Amezaga M., Kastelein R.A., Trinchieri G., and Hunter C.A. IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12-induced IFN-gamma. J. Immunol. 162 (1999) 5894-5901
50. Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., Takeuchi O., Sugiyama M., Okabe M., Takeda K., and Akira S. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301 (2003) 640-643
51. Yoneyama M., Suhara W., Fukuhara Y., Fukuda M., Nishida E., and Fujita T. Direct triggering of the type I interferon system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/p300. EMBO J. 17 (1998) 1087-1095