-
1
-
-
36048960251
-
Evaluation of physicochemical properties, skin permeation and accumulation profiles of ketorolac fatty ester prodrugs
-
Bhandari KH et al. Evaluation of physicochemical properties, skin permeation and accumulation profiles of ketorolac fatty ester prodrugs. Biol Pharm Bull 2007; 30: 2211-2216.
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 2211-2216
-
-
Bhandari, K.H.1
-
2
-
-
34447316150
-
Microemulsions as topical delivery vehicles for the anti-melanoma prodrug, temozolomide hexyl ester (TMZA-HE)
-
Suppasansatorn P et al. Microemulsions as topical delivery vehicles for the anti-melanoma prodrug, temozolomide hexyl ester (TMZA-HE). J Pharm Pharmacol 2007; 59; 787-794.
-
(2007)
J Pharm Pharmacol
, vol.59
, pp. 787-794
-
-
Suppasansatorn, P.1
-
3
-
-
0033751414
-
Prediction of transdermal flux of prodrugs of 5-fluorouracil, theophylline, and 6-mercaptopurine with a series/parallel model
-
Roberts WJ, Sloan KB. Prediction of transdermal flux of prodrugs of 5-fluorouracil, theophylline, and 6-mercaptopurine with a series/parallel model. J Pharm Sci 2000; 89: 1415-1431.
-
(2000)
J Pharm Sci
, vol.89
, pp. 1415-1431
-
-
Roberts, W.J.1
Sloan, K.B.2
-
4
-
-
2942551392
-
A duplex "Gemini" prodrug of naltrexone for transdermal delivery
-
Hammell DC et al. A duplex "Gemini" prodrug of naltrexone for transdermal delivery. J Control Release 2004; 97: 283-290.
-
(2004)
J Control Release
, vol.97
, pp. 283-290
-
-
Hammell, D.C.1
-
5
-
-
34447295359
-
Ester prodrugs of morphine improve transdermal drug delivery: A mechanistic study
-
Wang JJ et al. Ester prodrugs of morphine improve transdermal drug delivery: a mechanistic study. J Pharm Pharmacol 2007; 59: 917-925.
-
(2007)
J Pharm Pharmacol
, vol.59
, pp. 917-925
-
-
Wang, J.J.1
-
6
-
-
0027849619
-
The USA experience with the clonidine transdermal therapeutic system
-
Burris JF. The USA experience with the clonidine transdermal therapeutic system. Clin Auton Res 1993; 3: 391.
-
(1993)
Clin Auton Res
, vol.3
, pp. 391
-
-
Burris, J.F.1
-
7
-
-
31544444739
-
Design, synthesis and characterization of captopril prodrugs for enhanced percutaneous absorption
-
Moss GP et al. Design, synthesis and characterization of captopril prodrugs for enhanced percutaneous absorption. J Pharm Pharmacol 2006; 58: 167-177.
-
(2006)
J Pharm Pharmacol
, vol.58
, pp. 167-177
-
-
Moss, G.P.1
-
8
-
-
0018069608
-
The skin as a drug-metabolizing organ
-
Pannatier A et al. The skin as a drug-metabolizing organ. Drug Metab Rev 1978; 8: 319-343.
-
(1978)
Drug Metab Rev
, vol.8
, pp. 319-343
-
-
Pannatier, A.1
-
9
-
-
0019403369
-
Drug metabolism in skin. Comparative activity of the mixed-function oxidases, epoxide hydratase, and glutathione S-transferase in liver and skin of the neonatal rat
-
Mukhtar H, Bickers DR. Drug metabolism in skin. Comparative activity of the mixed-function oxidases, epoxide hydratase, and glutathione S-transferase in liver and skin of the neonatal rat. Drug Metab Dispos 1981; 9: 311-314.
-
(1981)
Drug Metab Dispos
, vol.9
, pp. 311-314
-
-
Mukhtar, H.1
Bickers, D.R.2
-
10
-
-
0029958121
-
Evaluation of stereoselective transdermal transport and concurrent cutaneous hydrolysis of several ester prodrugs of propranolol: Mechanism of stereoselective permeation
-
Ahmed S et al. Evaluation of stereoselective transdermal transport and concurrent cutaneous hydrolysis of several ester prodrugs of propranolol: mechanism of stereoselective permeation. Pharm Res 1996; 13: 1524-1529.
-
(1996)
Pharm Res
, vol.13
, pp. 1524-1529
-
-
Ahmed, S.1
-
11
-
-
0036892908
-
Straight-chain naltrexone ester prodrugs: Diffusion and concurrent esterase biotransformation in human skin
-
Stinchcomb AL et al. Straight-chain naltrexone ester prodrugs: diffusion and concurrent esterase biotransformation in human skin. J Pharm Sci 2002; 91: 2571-2578.
-
(2002)
J Pharm Sci
, vol.91
, pp. 2571-2578
-
-
Stinchcomb, A.L.1
-
12
-
-
39749175491
-
Evaluation of simultaneous permeation and metabolism of methyl nicotinate in human, snake, and shed snake skin
-
Ngawhirunpat T et al. Evaluation of simultaneous permeation and metabolism of methyl nicotinate in human, snake, and shed snake skin. Pharm Dev Technol 2008; 13: 75-83.
-
(2008)
Pharm Dev Technol
, vol.13
, pp. 75-83
-
-
Ngawhirunpat, T.1
-
13
-
-
34548409870
-
The distribution of esterases in the skin of the minipig
-
Jewell C et al. The distribution of esterases in the skin of the minipig. Toxicol Lett 2007; 173: 118-123.
-
(2007)
Toxicol Lett
, vol.173
, pp. 118-123
-
-
Jewell, C.1
-
14
-
-
33748328153
-
Topical delivery of retinyl ascorbate co-drug. 5. In vitro degradation studies
-
Abdulmajed K et al. Topical delivery of retinyl ascorbate co-drug. 5. In vitro degradation studies. Skin Pharmacol Physiol 2006; 19: 248-258.
-
(2006)
Skin Pharmacol Physiol
, vol.19
, pp. 248-258
-
-
Abdulmajed, K.1
-
15
-
-
33749236438
-
Skin delivery potency and antitumor activities of temozolomide ester prodrugs
-
Suppasansatorn P et al. Skin delivery potency and antitumor activities of temozolomide ester prodrugs. Cancer Lett 2006; 244: 42-52.
-
(2006)
Cancer Lett
, vol.244
, pp. 42-52
-
-
Suppasansatorn, P.1
-
16
-
-
33745618672
-
Comparison of skin esterase activities from different species
-
Prusakiewicz JJ et al. Comparison of skin esterase activities from different species. Pharm Res 2006; 23: 1517-1524.
-
(2006)
Pharm Res
, vol.23
, pp. 1517-1524
-
-
Prusakiewicz, J.J.1
-
17
-
-
0027070937
-
Ester hydrolysis and conjugation reactions in intact skin and skin homogenate, and by liver esterase of rabbits
-
Henrikus BM, Kampffmeyer HG. Ester hydrolysis and conjugation reactions in intact skin and skin homogenate, and by liver esterase of rabbits. Xenobiotica 1992; 22: 1357-1366.
-
(1992)
Xenobiotica
, vol.22
, pp. 1357-1366
-
-
Henrikus, B.M.1
Kampffmeyer, H.G.2
-
18
-
-
59049086479
-
-
British Pharmacopeia. Captopril monograph. In: British Pharmacopoeia. London: HMSO, 2003: 324-325.
-
British Pharmacopeia. Captopril monograph. In: British Pharmacopoeia. London: HMSO, 2003: 324-325.
-
-
-
-
19
-
-
0025288355
-
The metabolism of amethocaine by porcine and human skin extracts: Influence on percutaneous anaesthesia
-
Woolfson AD et al. The metabolism of amethocaine by porcine and human skin extracts: influence on percutaneous anaesthesia. Int J Pharm 1990; 62: 9.
-
(1990)
Int J Pharm
, vol.62
, pp. 9
-
-
Woolfson, A.D.1
-
20
-
-
0000125764
-
A new model for calculating atomic charges in molecules
-
Gasteiger J, Marsili M. A new model for calculating atomic charges in molecules. Tetrahedron Lett 1978; 19: 3181-3184.
-
(1978)
Tetrahedron Lett
, vol.19
, pp. 3181-3184
-
-
Gasteiger, J.1
Marsili, M.2
-
21
-
-
0003089312
-
Comparing simple linear equations
-
Zar JH, ed, 4th edn. Upper Saddle River, NJ: Prentice Hall
-
Zar JH. Comparing simple linear equations. In: Zar JH, ed. Biostatistical Analysis, 4th edn. Upper Saddle River, NJ: Prentice Hall, 1999: 360-376.
-
(1999)
Biostatistical Analysis
, pp. 360-376
-
-
Zar, J.H.1
-
22
-
-
0242516016
-
Synthesis and evaluation of ketorolac ester prodrugs for transdermal delivery
-
Doh HJ et al. Synthesis and evaluation of ketorolac ester prodrugs for transdermal delivery. J Pharm Sci 2003; 92: 1008-1017.
-
(2003)
J Pharm Sci
, vol.92
, pp. 1008-1017
-
-
Doh, H.J.1
-
23
-
-
0025084188
-
Enhanced delivery of zidovudine through rat and human skin via ester prodrugs
-
Seki T et al. Enhanced delivery of zidovudine through rat and human skin via ester prodrugs. Pharm Res 1990; 7: 948-952.
-
(1990)
Pharm Res
, vol.7
, pp. 948-952
-
-
Seki, T.1
-
24
-
-
0029705324
-
Automated docking of flexible ligands: Applications of AutoDock
-
Goodsell DS et al. Automated docking of flexible ligands: applications of AutoDock. J Mol Recognit 1996; 9: 1-5.
-
(1996)
J Mol Recognit
, vol.9
, pp. 1-5
-
-
Goodsell, D.S.1
-
25
-
-
27444434892
-
MetaSite: Understanding metabolism in human cytochromes from the perspective of the chemist
-
Cruciani G et al. MetaSite: understanding metabolism in human cytochromes from the perspective of the chemist. J Med Chem 2005; 48: 6970-6979.
-
(2005)
J Med Chem
, vol.48
, pp. 6970-6979
-
-
Cruciani, G.1
-
26
-
-
0021875517
-
Cutaneous biotransformation as a parameter in the modulation of the activity of topical corticosteroids
-
Cheung YW et al. Cutaneous biotransformation as a parameter in the modulation of the activity of topical corticosteroids. Int J Pharm 1985; 26: 175.
-
(1985)
Int J Pharm
, vol.26
, pp. 175
-
-
Cheung, Y.W.1
-
27
-
-
0034898142
-
In vitro and in vivo evaluation of polyoxyethylene esters as dermal prodrugs of ketoprofen, naproxen and diclofenac
-
Bonina FP et al. In vitro and in vivo evaluation of polyoxyethylene esters as dermal prodrugs of ketoprofen, naproxen and diclofenac. Eur J Pharm Sci 2001; 14: 123-134.
-
(2001)
Eur J Pharm Sci
, vol.14
, pp. 123-134
-
-
Bonina, F.P.1
-
28
-
-
15044355680
-
Ketorolac amide prodrugs for transdermal delivery: Stability and in vitro rat skin permeation studies
-
Kim BY et al. Ketorolac amide prodrugs for transdermal delivery: stability and in vitro rat skin permeation studies. Int J Pharm 2005; 293: 193-202.
-
(2005)
Int J Pharm
, vol.293
, pp. 193-202
-
-
Kim, B.Y.1
-
29
-
-
0020059595
-
Epidermis: A site of drug metabolism in neonatal rat skin. Studies on cytochrome P-450 content and mixed-function oxidase and epoxide hydrolase activity
-
Bickers DR et al. Epidermis: a site of drug metabolism in neonatal rat skin. Studies on cytochrome P-450 content and mixed-function oxidase and epoxide hydrolase activity. Mol Pharmacol 1982; 21: 239-247.
-
(1982)
Mol Pharmacol
, vol.21
, pp. 239-247
-
-
Bickers, D.R.1
-
30
-
-
33646411475
-
Analysis of in vitro skin permeation of 22-oxacalcitriol having a complicated metabolic pathway
-
Yamaguchi K et al. Analysis of in vitro skin permeation of 22-oxacalcitriol having a complicated metabolic pathway. Pharm Res 2006; 23: 680-688.
-
(2006)
Pharm Res
, vol.23
, pp. 680-688
-
-
Yamaguchi, K.1
-
31
-
-
0018898875
-
Variations in percutaneous absorption of testosterone in the rhesus monkey due to anatomic site of application and frequency of application
-
Wester RC et al. Variations in percutaneous absorption of testosterone in the rhesus monkey due to anatomic site of application and frequency of application. Arch Dermatol Res 1980; 267: 229-235.
-
(1980)
Arch Dermatol Res
, vol.267
, pp. 229-235
-
-
Wester, R.C.1
-
32
-
-
0029041381
-
Reproduction and the renin-angiotensin system
-
Ganong WF. Reproduction and the renin-angiotensin system. Neurosci Biobehav Rev 1995; 19: 241.
-
(1995)
Neurosci Biobehav Rev
, vol.19
, pp. 241
-
-
Ganong, W.F.1
|