A yeast two-hybrid assay provides a simple way to evaluate the vast majority of hMLH1 germ-line mutations

Cancer Research

Volumn 63, Issue 12, 2003, Pages 3302-3308

  Kondo, Emiko ^a   Suzuki, Hideyuki ^a   Horii, Akira ^a   Fukushige, Shinichi ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GENE PRODUCT; PROTEIN MLH1;

AMINO ACID SUBSTITUTION; ANALYTIC METHOD; ARTICLE; CARBOXY TERMINAL SEQUENCE; COLON CARCINOGENESIS; COLORECTAL CANCER; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA POLYMORPHISM; ENZYME ACTIVITY; GENE; GENE FREQUENCY; GENE HMLH1; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GERM LINE; HUMAN; MISSENSE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN INTERACTION; RELIABILITY; SITE DIRECTED MUTAGENESIS; TWO HYBRID SYSTEM; YEAST;

ADENOCARCINOMA; AMINO ACID MOTIFS; AMINO ACID SUBSTITUTION; CARRIER PROTEINS; CODON, NONSENSE; CODON, TERMINATOR; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MUTATIONAL ANALYSIS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FRAMESHIFT MUTATION; GENE LIBRARY; GERM-LINE MUTATION; HUMANS; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; POLYMORPHISM, GENETIC; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0038407386     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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