Synergistic neuroprotective effect via simian lentiviral vector-mediated simultaneous gene transfer of human pigment epithelium-derived factor and human fibroblast growth factor-2 in rodent models of retinitis pigmentosa

Journal of Gene Medicine

Volumn 10, Issue 12, 2008, Pages 1273-1281

  Miyazaki, Masanori ^a   Ikeda, Yasuhiro ^a   Yonemitsu, Yoshikazu ^b   Goto, Yoshinobu ^c   Kohno, Ri ichiro ^a   Murakami, Yusuke ^a   Inoue, Makoto ^d   Ueda, Yasuji ^b   Hasegawa, Mamoru ^d   Tobimatsu, Shozo ^a   Sueishi, Katsuo ^a   Ishibashi, Tatsuro ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c INTERNATIONAL UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^d DNAVEC Corporation   (Japan)

Author keywords

Fibroblast growth factor 2; Neuroprotection; Pigment epithelium derived factor; Retinitis pigmentosa; Royal College of Surgeons rats; Simian immunodeficiency virus

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 2; LENTIVIRUS VECTOR; PIGMENT EPITHELIUM DERIVED FACTOR; EYE PROTEIN; FIBROBLAST GROWTH FACTOR 2; GREEN FLUORESCENT PROTEIN; NERVE GROWTH FACTOR; PIGMENT EPITHELIUM-DERIVED FACTOR; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG SAFETY; ELECTRORETINOGRAPHY; GENE EXPRESSION; GENE TARGETING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; MONOTHERAPY; MOUSE; NEUROPROTECTION; NONHUMAN; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; RETINITIS PIGMENTOSA; SIMIAN IMMUNODEFICIENCY VIRUS; TREATMENT RESPONSE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ANIMAL; DISEASE MODEL; GENE VECTOR; GENETICS; METABOLISM; TRANSGENE;

ANIMALIA; MUS; RATTUS; RODENTIA; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

ANIMALS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; EYE PROTEINS; FIBROBLAST GROWTH FACTOR 2; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; MICE; NERVE GROWTH FACTORS; RATS; RETINITIS PIGMENTOSA; SERPINS; SIMIAN IMMUNODEFICIENCY VIRUS; TRANSGENES;

EID: 58949084050     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1257     Document Type: Article

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