Sustained delivery of NT-3 from lens fiber cells in transgenic mice reveals specificity of neuroprotection in retinal degenerations

Journal of Comparative Neurology

Volumn 511, Issue 6, 2008, Pages 724-735

  Lavail, Matthew M ^a   Nishikawa, Shimpei ^a,f   Duncan, Jacque L ^a   Yang, Haidong ^a   Matthes, Michael T ^a   Yasumura, Douglas ^a   Vollrath, Doulgas ^b   Overbeek, Paul A ^c   Ash, John D ^d   Robinson, Michael L ^e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^e MIAMI UNIVERSITY   (United States)

^f NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Mertk; Neurotrophic factor; Q344ter; Rd; Retinal degeneration

Indexed keywords

ALPHA CRYSTALLIN; NEUROTROPHIN 3; PRIMER DNA; RHODOPSIN; MERTK PROTEIN, MOUSE; MESSENGER RNA; ONCOPROTEIN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE CONSTRUCT; GENE INSERTION; GENE LOCATION; GENE OVEREXPRESSION; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; KNOCKOUT MOUSE; LENS FIBER; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RETINA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CELL PROTECTION; EPITHELIUM CELL; GENETICS; IMMUNOHISTOCHEMISTRY; LENS; LIGHT; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHOTORECEPTOR CELL; RADIATION EXPOSURE; SECRETION; TIME; TRANSGENE;

ANIMALS; CYTOPROTECTION; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; IMMUNOHISTOCHEMISTRY; LENS, CRYSTALLINE; LIGHT; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; NEUROTROPHIN 3; PHOTORECEPTOR CELLS, VERTEBRATE; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RETINAL DEGENERATION; RNA, MESSENGER; TIME FACTORS; TRANSGENES;

EID: 58749094300     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.21858     Document Type: Article

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