Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration

Journal of Neuroscience

Volumn 24, Issue 25, 2004, Pages 5651-5658

  Grimm, Christian ^a,e   Wenzel, Andreas ^a   Stanescu, Dinu ^a   Samardzija, Marijana ^a   Hotop, Svenja ^a   Groszer, Mathias ^b   Naash, Muna ^c   Gassmann, Max ^d   Remé, Charlotte ^a  

^a University Eye Hospital   (Switzerland)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITÄTSSPITAL ZÜRICH   (Switzerland)

Author keywords

Apoptosis; Erythropoietin; Neuroprotection; Photoreceptor; Retinal degeneration; Transgene

Indexed keywords

RECOMBINANT ERYTHROPOIETIN;

ADAPTATION; ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL LOSS; CONSTITUTIVE OVEREXPRESSION; CONTROLLED STUDY; GENE OVEREXPRESSION; HYPOXIA; MOUSE; MOUSE MUTANT; MOUSE STRAIN; NEUROPROTECTION; NEWBORN; NONHUMAN; PHOTORECEPTOR; PHOTOTOXICITY; PRIORITY JOURNAL; RD1 MOUSE; RECEPTOR DOWN REGULATION; RETINA DEGENERATION; RETINA DYSTROPHY; RETINITIS PIGMENTOSA; TRANSGENE; TRANSGENIC MOUSE; VPP MOUSE;

ANIMALS; APOPTOSIS; ERYTHROPOIETIN; HUMANS; IMMUNOHISTOCHEMISTRY; LIGHT; MICE; MICE, TRANSGENIC; MUTATION; PHOSPHORIC DIESTER HYDROLASES; PHOTORECEPTORS; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; RETINA; RETINAL DEGENERATION; RHODOPSIN;

EID: 3042743240     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1288-04.2004     Document Type: Article

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