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Volumn 100, Issue 2, 2009, Pages 327-333

Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; GLUCOSE; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; MACROCYCLIC COMPOUND; RAPAMYCIN; UNCLASSIFIED DRUG; VERSIPELOSTATIN;

EID: 58549115710     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2008.01036.x     Document Type: Article
Times cited : (28)

References (35)
  • 1
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
    • Brown JM, Giaccia AJ. The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 1998; 58: 1408-16.
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 2
    • 33947402280 scopus 로고    scopus 로고
    • The unfolded protein response and cancer: A brighter future unfolding?
    • Scrivaen P, Brown NJ, Pockley AG, Wyld L. The unfolded protein response and cancer: A brighter future unfolding? J Mol Med 2007; 85: 331-41.
    • (2007) J Mol Med , vol.85 , pp. 331-341
    • Scrivaen, P.1    Brown, N.J.2    Pockley, A.G.3    Wyld, L.4
  • 3
    • 33745844503 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in health and disease
    • Zhao L, Ackerman SL. Endoplasmic reticulum stress in health and disease. Curr Opin Cell Biol 2006; 18: 1-9.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 1-9
    • Zhao, L.1    Ackerman, S.L.2
  • 4
    • 10344222124 scopus 로고    scopus 로고
    • The role of the unfolded protein response in tumor development: Friend or foe?
    • Ma Y, Hendershot LM. The role of the unfolded protein response in tumor development: Friend or foe? Nat Rev Cancer 2004; 4: 966-77.
    • (2004) Nat Rev Cancer , vol.4 , pp. 966-977
    • Ma, Y.1    Hendershot, L.M.2
  • 5
    • 34248571826 scopus 로고    scopus 로고
    • GRP78 induction in cancer: Therapeutic and prognostic implications
    • Lee AS. GRP78 induction in cancer: Therapeutic and prognostic implications. Cancer Res 2007; 67: 3496-9.
    • (2007) Cancer Res , vol.67 , pp. 3496-3499
    • Lee, A.S.1
  • 6
    • 33748076770 scopus 로고    scopus 로고
    • GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer
    • Lee E, Nichols P, Spicer D, Groshen S, Yu MC, Lee AS. GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer. Cancer Res 2007; 66: 7849-53.
    • (2007) Cancer Res , vol.66 , pp. 7849-7853
    • Lee, E.1    Nichols, P.2    Spicer, D.3    Groshen, S.4    Yu, M.C.5    Lee, A.S.6
  • 7
    • 35448967382 scopus 로고    scopus 로고
    • The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas
    • Pyrko P, Schonthal AH, Hofman FM, Chen TC, Lee AS. The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res 2007; 67: 9809-16.
    • (2007) Cancer Res , vol.67 , pp. 9809-9816
    • Pyrko, P.1    Schonthal, A.H.2    Hofman, F.M.3    Chen, T.C.4    Lee, A.S.5
  • 8
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007; 8: 519-29.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 9
    • 33749492425 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress signalling in disease
    • Marciniak SJ, Ron D. Endoplasmic reticulum stress signalling in disease. Physiol Rev 2006; 86: 1133-49.
    • (2006) Physiol Rev , vol.86 , pp. 1133-1149
    • Marciniak, S.J.1    Ron, D.2
  • 10
    • 39049160268 scopus 로고    scopus 로고
    • Critical role in the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development
    • Dong D, Ni M, Li J et al. Critical role in the stress chaperone GRP78/ BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res 2008; 68: 498-505.
    • (2008) Cancer Res , vol.68 , pp. 498-505
    • Dong, D.1    Ni, M.2    Li, J.3
  • 11
    • 27144458505 scopus 로고    scopus 로고
    • ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
    • Bi M, Naczki C, Koritzinsky M et al. ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J 2005; 24: 3470-81.
    • (2005) EMBO J , vol.24 , pp. 3470-3481
    • Bi, M.1    Naczki, C.2    Koritzinsky, M.3
  • 12
    • 0033634641 scopus 로고    scopus 로고
    • Perk is essential for translational regulation and cell survival during the unfolded protein response
    • Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 2000; 5: 897-04.
    • (2000) Mol Cell , vol.5 , pp. 804-897
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 13
    • 10644233167 scopus 로고    scopus 로고
    • CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
    • Marciniak SJ, Yun CY, Oyadomari S et al. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 2004; 18: 3066-77.
    • (2004) Genes Dev , vol.18 , pp. 3066-3077
    • Marciniak, S.J.1    Yun, C.Y.2    Oyadomari, S.3
  • 14
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic reticulum-resident kinase
    • Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic reticulum-resident kinase. Nature 1999; 397: 271-4.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 15
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, Novoa I, Zhang Y et al. Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 2000; 6: 1099-08.
    • (2000) Mol Cell , vol.6 , pp. 1008-1099
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3
  • 16
    • 0041315834 scopus 로고    scopus 로고
    • Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress
    • Ma Y, Hendershot LM. Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress. J Biol Chem 2003; 278: 34 864-73.
    • (2003) J Biol Chem , vol.278 , pp. 34864-34873
    • Ma, Y.1    Hendershot, L.M.2
  • 17
    • 0041703031 scopus 로고    scopus 로고
    • The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress-elucidation by GADD34-deficient mice
    • Kojima E, Takeuchi A, Haneda M et al. The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress-elucidation by GADD34-deficient mice. FASEB J 2003; 17: 1573-5.
    • (2003) FASEB J , vol.17 , pp. 1573-1575
    • Kojima, E.1    Takeuchi, A.2    Haneda, M.3
  • 18
    • 0037416211 scopus 로고    scopus 로고
    • Stress-induce gene expression requires programmed recovery from translational repression
    • Novoa I, Zhang Y, Zeng H, Jungreis R, Harding HP, Ron D. Stress-induce gene expression requires programmed recovery from translational repression. EMBO J 2003; 22: 1180-7.
    • (2003) EMBO J , vol.22 , pp. 1180-1187
    • Novoa, I.1    Zhang, Y.2    Zeng, H.3    Jungreis, R.4    Harding, H.P.5    Ron, D.6
  • 19
    • 38849180436 scopus 로고    scopus 로고
    • Targeting the eukaryotic translation initiation factor 4E for cancer therapy
    • Graff JR, Konicek BW, Carter JH, Marcusson EG. Targeting the eukaryotic translation initiation factor 4E for cancer therapy. Cancer Res 2008; 68: 631-4.
    • (2008) Cancer Res , vol.68 , pp. 631-634
    • Graff, J.R.1    Konicek, B.W.2    Carter, J.H.3    Marcusson, E.G.4
  • 20
    • 33646764191 scopus 로고    scopus 로고
    • The cap-dependent translation apparatus integrates and amplifies cancer pathway
    • Polunovsky VA, Bitterman PB. The cap-dependent translation apparatus integrates and amplifies cancer pathway. RNA Biol 2006; 3: 10-17.
    • (2006) RNA Biol , vol.3 , pp. 10-17
    • Polunovsky, V.A.1    Bitterman, P.B.2
  • 21
    • 0037154965 scopus 로고    scopus 로고
    • Gene-specific regulation by general translation factors
    • Dever TE. Gene-specific regulation by general translation factors. Cell 2002; 108: 545-56.
    • (2002) Cell , vol.108 , pp. 545-556
    • Dever, T.E.1
  • 22
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • Gingras A, Raught B, Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes Dev 2001; 15: 807-26.
    • (2001) Genes Dev , vol.15 , pp. 807-826
    • Gingras, A.1    Raught, B.2    Sonenberg, N.3
  • 23
    • 0033153166 scopus 로고    scopus 로고
    • Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism
    • Gingras A, Gygi SP, Raught B et al. Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism. Genes Dev 1999; 13: 1422-37.
    • (1999) Genes Dev , vol.13 , pp. 1422-1437
    • Gingras, A.1    Gygi, S.P.2    Raught, B.3
  • 24
    • 33751285479 scopus 로고    scopus 로고
    • The PERK/eIF2α/ATF4 module of the UPR in hypoxia resistance and tumor growth
    • Fels DR, Koumenis C. The PERK/eIF2α/ATF4 module of the UPR in hypoxia resistance and tumor growth. Cancer Biol Ther 2006; 5: 723-8.
    • (2006) Cancer Biol Ther , vol.5 , pp. 723-728
    • Fels, D.R.1    Koumenis, C.2
  • 25
    • 4444302042 scopus 로고    scopus 로고
    • Effect on tumor cells of blocking survival response to glucose deprivation
    • Park H, Tomida A, Sato S et al. Effect on tumor cells of blocking survival response to glucose deprivation. J Natl Cancer Inst 2004; 96: 1300-10.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1300-1310
    • Park, H.1    Tomida, A.2    Sato, S.3
  • 26
    • 0037079237 scopus 로고    scopus 로고
    • SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin
    • Horie K, Tomida A, Sugimoto Y et al. SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin. Oncogene 2002; 21: 7913-22.
    • (2002) Oncogene , vol.21 , pp. 7913-7922
    • Horie, K.1    Tomida, A.2    Sugimoto, Y.3
  • 27
    • 0034637435 scopus 로고    scopus 로고
    • Translational control of the antiapoptotic function of Ras
    • Polunovsky VA, Gingras A, Sonenberg N et al. Translational control of the antiapoptotic function of Ras. J Biol Chem 2000; 275: 24 776-80.
    • (2000) J Biol Chem , vol.275 , pp. 24776-24780
    • Polunovsky, V.A.1    Gingras, A.2    Sonenberg, N.3
  • 28
    • 35748975933 scopus 로고    scopus 로고
    • Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation
    • Tsukumo Y, Akihiro T, Kitahara O. Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation. J Biol Chem 2007; 282: 29 264-72.
    • (2007) J Biol Chem , vol.282 , pp. 29264-29272
    • Tsukumo, Y.1    Akihiro, T.2    Kitahara, O.3
  • 29
    • 0042031047 scopus 로고    scopus 로고
    • A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets
    • Arsham AM, Howell JJ, Simon MC. A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets. J Biol Chem 2003; 32: 29 655-60.
    • (2003) J Biol Chem , vol.32 , pp. 29655-29660
    • Arsham, A.M.1    Howell, J.J.2    Simon, M.C.3
  • 30
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
    • Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Meth 1986; 89: 271-7.
    • (1986) J Immunol Meth , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 31
    • 39649107702 scopus 로고    scopus 로고
    • ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress
    • Yamaguchi Y, Ishihara H, Yamada T et al. ATF4-mediated induction of 4E-BP1 contributes to pancreatic β cell survival under endoplasmic reticulum stress. Cell Metab 2008; 7: 269-76.
    • (2008) Cell Metab , vol.7 , pp. 269-276
    • Yamaguchi, Y.1    Ishihara, H.2    Yamada, T.3
  • 32
    • 33644852277 scopus 로고    scopus 로고
    • Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control
    • Koritzinsky M, Magagnin MG, Beucken T et al. Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control. EMBO J 2006; 25: 1114-25.
    • (2006) EMBO J , vol.25 , pp. 1114-1125
    • Koritzinsky, M.1    Magagnin, M.G.2    Beucken, T.3
  • 33
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • Hudes G, Carducci M, Tomczak P et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007; 356: 2271-81.
    • (2007) N Engl J Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 34
    • 48649107474 scopus 로고    scopus 로고
    • Efficiency of everolimus in advanced renal cell carcinoma: A double-blind, randomized, placebo-controlled phase III trial
    • Motzer R, Escudier B, Oudard S et al. Efficiency of everolimus in advanced renal cell carcinoma: A double-blind, randomized, placebo-controlled phase III trial. Lancet 2008; 372: 449-56.
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.1    Escudier, B.2    Oudard, S.3
  • 35
    • 40349106029 scopus 로고    scopus 로고
    • The potential role of mTOR inhibitors in non-small cell lung cancer
    • Gridelli C, Maione P, Rossi A. The potential role of mTOR inhibitors in non-small cell lung cancer. Oncologist 2007; 13: 139-47.
    • (2007) Oncologist , vol.13 , pp. 139-147
    • Gridelli, C.1    Maione, P.2    Rossi, A.3


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