Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 2, 2009, Pages 553-557

  Thiry, Anne ^a   Ledecq, Marie ^a   Cecchi, Alessandro ^b   Frederick, Raphael ^a   Dogné, Jean Michel ^a   Supuran, Caudiu T ^b   Wouters, Johan ^a   Masereel, Bernard ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Carbonic anhydrase; Pharmacophore; Sulfonamides; Virtual screening

Indexed keywords

ACETAZOLAMIDE; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE INHIBITOR; CARBONATE DEHYDRATASE IX; LIGAND;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; ENZYME INHIBITION; MOLECULAR DOCKING; PHARMACOPHORE;

ANTIGENS, NEOPLASM; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; COMPUTER SIMULATION; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 58549100656     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.11.071     Document Type: Article

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