Isoflurane modulates excitability in the mouse thalamus via GABA-dependent and GABA-independent mechanisms

Neuropharmacology

Volumn 56, Issue 2, 2009, Pages 438-447

  Ying, Shui Wang ^a   Werner, David F ^b   Homanics, Gregg E ^b   Harrison, Neil L ^a   Goldstein, Peter A ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Potassium channel; Reticular thalamic nucleus (RTN); ventrobasal (VB) thalamus; Volatile anesthetic

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOPYRIDINE; BARIUM; GAMMA AMINOBUTYRIC ACID A RECEPTOR ALPHA1; ISOFLURANE; RECOMBINANT RECEPTOR; UNCLASSIFIED DRUG; ZOLPIDEM;

ACTION POTENTIAL; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG MECHANISM; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; GENE MUTATION; GENOTYPE; INHIBITORY POSTSYNAPTIC POTENTIAL; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; REBOUND; THALAMUS;

4-AMINOPYRIDINE; ACTION POTENTIALS; ALANINE; ANESTHETICS, INHALATION; ANIMALS; BIOPHYSICS; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; HISTIDINE; INHIBITORY POSTSYNAPTIC POTENTIALS; ISOFLURANE; LEUCINE; MICE; MICE, TRANSGENIC; MUTATION; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; PYRIDAZINES; RECEPTORS, GABA-A; SERINE; THALAMUS; TIME FACTORS;

EID: 58549100304     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2008.09.015     Document Type: Article

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