Computational Design of Calmodulin Mutants with up to 900-Fold Increase in Binding Specificity

Journal of Molecular Biology

Volumn 385, Issue 5, 2009, Pages 1470-1480

  Yosef, Eliyahu ^a   Politi, Regina ^a   Choi, Mee H ^b   Shifman, Julia M ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

calmodulin; computational protein design; protein binding specificity; protein protein interactions

Indexed keywords

CALMODULIN;

ARTICLE; BINDING AFFINITY; CALCIUM SIGNALING; MATHEMATICAL COMPUTING; MUTANT; MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN VARIANT;

EID: 58549091879     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.09.053     Document Type: Article

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