In70 of plasmid pAX22, a blaVIM-1-containing integron carrying a new aminoglycoside phosphotransferase gene cassette

Antimicrobial Agents and Chemotherapy

Volumn 45, Issue 4, 2001, Pages 1249-1253

  Riccio, M L ^a   Pallecchi, L ^a   Fontana, R ^a   Rossolini, G M ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE; AMPICILLIN; AZTREONAM; BETA LACTAM; BETA LACTAMASE; CARBAPENEM; CEFOTAXIME; CEFTAZIDIME; GENE PRODUCT; GENTAMICIN; IMIPENEM; KANAMYCIN; MEROPENEM; METALLO BETA LACTASE; MEZLOCILLIN; NEOMYCIN; NETILMICIN; PHOSPHOTRANSFERASE; PIPERACILLIN; PROTEIN APHA15; SPECTINOMYCIN; STREPTOMYCIN; TOBRAMYCIN; UNCLASSIFIED DRUG;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIUM ISOLATION; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVITY; ENZYME ASSAY; ESCHERICHIA COLI; GENE CASSETTE; GENE EXPRESSION; GENE STRUCTURE; GENETIC CODE; INTEGRON; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; THIOTRICHACEAE; TRANSPOSON;

ALCALIGENES; AMINO ACID SEQUENCE; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; DNA TRANSPOSABLE ELEMENTS; GENE ORDER; GENES, BACTERIAL; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; KANAMYCIN KINASE; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PLASMIDS; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0035076960     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.45.4.1249-1253.2001     Document Type: Article

References (27)

1. Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5
2. Characterization of In0 of Pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of gram-negative bacteria
3. The integrons In0, In2, and In5 are defective transposon derivatives
4. New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pBWH301
5. In vitro activities of quinolones, β-lactams, tobramycin, and trimethoprim-sulfamethoxazole against nonfermentative gram-negative bacilli
6. Purification and biochemical characterization of the VIM-1 metallo-β-lactamase
7. Sequence and characterization of a novel chromosomal aminoglycoside phosphotransferase gene, aph(3′)-IIb, in Pseudomonas aeruginosa
8. Mobile gene cassettes and integrons: Capture and spread of genes by site-specific recombination
9. Integrons found in different locations have identical 5′ ends but variable 3′ ends
10. A spontaneous mutation in the aac(6′)-Ib gene results in altered substrate specificity of aminoglycoside 6′-N-acetyltransferase of a Pseudomonas fluorescens strain
11. IMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes
12. VIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate
13. Diversity and relative strength of tandem promoters for the antibiotic resistance genes of several integrons
14. Carbapenem-hydrolyzing β-lactamases in Pseudomonas aeruginosa
15. Characterization of VIM-2, a carbapenem-hydrolyzing metallo-β-lactamase and its plasmid- and integron-borne gene from a Pseudomonas aeruginosa clinical isolate in France
16. Transposon Tn5090 of plasmid R751, which carries an integron, is related to Tn7, Mu, and the retroelements
17. Gene cassettes: A new class of mobile element
18. Origins of the mobile gene cassettes found in integrons
19. VIM metallo-β-lactamase determinants, Italy
20. Acinetobacter, Achromobacter, Alcaligenes, Moraxella, Methylobacterium, and other nonfermentative gram-negative rods
21. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes
22. Susceptibilities of non-Pseudomonas aeruginosa gram-negative nonfermentative rods to ciprofloxacin, ofloxacin, levofloxacin, D-ofloxacin, sparfloxacin, ceftazidime, piperacillin, piperacillin-tazobactam, trimethoprim-sulphamethoxazole, and imipenem
23. Structure and function of 59-base element recombination sites associated with mobile gene cassettes
24. Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece