메뉴 건너뛰기




Volumn 105, Issue 51, 2008, Pages 20398-20403

CTCF-dependent enhancer-blocking by alternative chromatin loop formation

Author keywords

Beta globin genes; Epigenetics; Insulator; Locus control region; Transcription regulation

Indexed keywords

BETA GLOBIN; RNA POLYMERASE II; SMALL INTERFERING RNA;

EID: 58149498240     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808506106     Document Type: Article
Times cited : (156)

References (43)
  • 1
    • 0042978644 scopus 로고    scopus 로고
    • Visualization of chromatin domains created by the gypsy insulator of Drosophila
    • Byrd K, Corces VG (2003) Visualization of chromatin domains created by the gypsy insulator of Drosophila. J Cell Biol 162:565-574.
    • (2003) J Cell Biol , vol.162 , pp. 565-574
    • Byrd, K.1    Corces, V.G.2
  • 2
    • 9444232851 scopus 로고    scopus 로고
    • Boundary elements and nuclear organization
    • Capelson M, Corces VG (2004) Boundary elements and nuclear organization. Biol Cell 96:617-629.
    • (2004) Biol Cell , vol.96 , pp. 617-629
    • Capelson, M.1    Corces, V.G.2
  • 3
    • 35548990188 scopus 로고    scopus 로고
    • We gather together: Insulators and genome organization
    • Wallace JA, Felsenfeld G (2007) We gather together: insulators and genome organization. Curr Opin Genet Dev 17:400-407.
    • (2007) Curr Opin Genet Dev , vol.17 , pp. 400-407
    • Wallace, J.A.1    Felsenfeld, G.2
  • 4
    • 3543018516 scopus 로고    scopus 로고
    • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops
    • Murrell A, Heeson S, Reik W (2004) Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet 36:889-893.
    • (2004) Nat Genet , vol.36 , pp. 889-893
    • Murrell, A.1    Heeson, S.2    Reik, W.3
  • 5
    • 33746063711 scopus 로고    scopus 로고
    • CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
    • Kurukuti S, et al. (2006) CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci USA 103:10684-10689.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 10684-10689
    • Kurukuti, S.1
  • 6
    • 34247576603 scopus 로고    scopus 로고
    • Analysis of the H19ICR insulator
    • Yoon YS, et al. (2007) Analysis of the H19ICR insulator. Mol Cell Biol 27:3499-3510.
    • (2007) Mol Cell Biol , vol.27 , pp. 3499-3510
    • Yoon, Y.S.1
  • 7
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • Bell AC, West AG, Felsenfeld G (1999) The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98:387-396.
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 8
    • 1842505303 scopus 로고    scopus 로고
    • Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance
    • Pant V, et al. (2004) Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance. Mol Cell Biol 24:3497-3504.
    • (2004) Mol Cell Biol , vol.24 , pp. 3497-3504
    • Pant, V.1
  • 9
    • 29444448047 scopus 로고    scopus 로고
    • On a chromosome far, far away: LCRs and gene regulation
    • Dean A (2006) On a chromosome far, far away: LCRs and gene regulation. Trends Genet 22(1):38-45.
    • (2006) Trends Genet , vol.22 , Issue.1 , pp. 38-45
    • Dean, A.1
  • 11
    • 0036923833 scopus 로고    scopus 로고
    • Looping and interaction between hypersensitive sites in the active β-globin locus
    • Tolhuis B, Palstra RJ, Splinter E, Grosveld F, de Laat W (2002) Looping and interaction between hypersensitive sites in the active β-globin locus. Mol Cell 10:1453-1465.
    • (2002) Mol Cell , vol.10 , pp. 1453-1465
    • Tolhuis, B.1    Palstra, R.J.2    Splinter, E.3    Grosveld, F.4    de Laat, W.5
  • 12
    • 13244272059 scopus 로고    scopus 로고
    • Proximity among distant regulatory elements at the β-globin locus requires GATA-1 and FOG-1
    • Vakoc CR, et al. (2005) Proximity among distant regulatory elements at the β-globin locus requires GATA-1 and FOG-1. Mol Cell 17:453-462.
    • (2005) Mol Cell , vol.17 , pp. 453-462
    • Vakoc, C.R.1
  • 13
    • 5444255213 scopus 로고    scopus 로고
    • The active spatial organization of the β-globin locus requires the transcription factor EKLF
    • Drissen R, et al. (2004) The active spatial organization of the β-globin locus requires the transcription factor EKLF. Genes Dev 18:2485-2490.
    • (2004) Genes Dev , vol.18 , pp. 2485-2490
    • Drissen, R.1
  • 14
    • 33748259774 scopus 로고    scopus 로고
    • CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus
    • Splinter E, et al. (2006) CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev 20:2349-2354.
    • (2006) Genes Dev , vol.20 , pp. 2349-2354
    • Splinter, E.1
  • 15
    • 0141730403 scopus 로고    scopus 로고
    • The β-globin nuclear compartment in development and erythroid differentiation
    • Palstra RJ, et al. (2003) The β-globin nuclear compartment in development and erythroid differentiation. Nat Genet 35:190-194.
    • (2003) Nat Genet , vol.35 , pp. 190-194
    • Palstra, R.J.1
  • 16
    • 0032402123 scopus 로고    scopus 로고
    • Description and targeted deletion of 5′ hypersensitive site 5 and 6 of the mouse β-globin locus control region
    • Bender MA, et al. (1998) Description and targeted deletion of 5′ hypersensitive site 5 and 6 of the mouse β-globin locus control region. Blood 92:4394-4403.
    • (1998) Blood , vol.92 , pp. 4394-4403
    • Bender, M.A.1
  • 17
    • 0034687661 scopus 로고    scopus 로고
    • A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse β-globin locus
    • Farrell CM, et al. (2000) A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse β-globin locus. Proc Natl Acad Sci USA 97:14554-14559.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 14554-14559
    • Farrell, C.M.1
  • 18
    • 0033602445 scopus 로고    scopus 로고
    • Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice
    • Tanimoto K, Liu Q, Bungert J, Engel JD (1999) Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice. Nature 398:344-348.
    • (1999) Nature , vol.398 , pp. 344-348
    • Tanimoto, K.1    Liu, Q.2    Bungert, J.3    Engel, J.D.4
  • 19
    • 0043239344 scopus 로고    scopus 로고
    • HS5 of the human beta-globin locus control region: A developmental stage-specific border in erythroid cells
    • Wai AW, et al. (2003) HS5 of the human beta-globin locus control region: a developmental stage-specific border in erythroid cells. EMBO J 22:4489-4500.
    • (2003) EMBO J , vol.22 , pp. 4489-4500
    • Wai, A.W.1
  • 20
    • 0344629446 scopus 로고    scopus 로고
    • Human beta-globin locus control region HS5 contains CTCF-and developmental stage-dependent enhancer-blocking activity in erythroid cells
    • Tanimoto K, et al. (2003) Human beta-globin locus control region HS5 contains CTCF-and developmental stage-dependent enhancer-blocking activity in erythroid cells. Mol Cell Biol 23:8946-8952.
    • (2003) Mol Cell Biol , vol.23 , pp. 8946-8952
    • Tanimoto, K.1
  • 21
    • 0042091987 scopus 로고    scopus 로고
    • A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse β-globin locus
    • Bulger M, et al. (2003) A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse β-globin locus. Mol Cell Biol 23:5234-5244.
    • (2003) Mol Cell Biol , vol.23 , pp. 5234-5244
    • Bulger, M.1
  • 22
    • 34250183131 scopus 로고    scopus 로고
    • Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation
    • Kim SI, Bultman SJ, Jing H, Blobel GA, Bresnick EH (2007) Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation. Mol Cell Biol 27:4551-4565.
    • (2007) Mol Cell Biol , vol.27 , pp. 4551-4565
    • Kim, S.I.1    Bultman, S.J.2    Jing, H.3    Blobel, G.A.4    Bresnick, E.H.5
  • 23
    • 0037447160 scopus 로고    scopus 로고
    • The β-globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation
    • Sawado T, Halow J, Bender MA, Groudine M (2003) The β-globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation. Genes Dev 17:1009-1018.
    • (2003) Genes Dev , vol.17 , pp. 1009-1018
    • Sawado, T.1    Halow, J.2    Bender, M.A.3    Groudine, M.4
  • 24
    • 0032478276 scopus 로고    scopus 로고
    • CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation
    • Blobel GA, Nakajima T, Eckner R, Montminy M, Orkin SH (1998) CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc Natl Acad Sci USA 95:2061-2066.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2061-2066
    • Blobel, G.A.1    Nakajima, T.2    Eckner, R.3    Montminy, M.4    Orkin, S.H.5
  • 25
    • 0032544123 scopus 로고    scopus 로고
    • Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activity by interaction with histone acetyltransferases
    • Zhang W, Bieker JJ (1998) Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activity by interaction with histone acetyltransferases. Proc Natl Acad Sci USA 95:9855-9860.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9855-9860
    • Zhang, W.1    Bieker, J.J.2
  • 26
    • 0031032776 scopus 로고    scopus 로고
    • The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2
    • Cheng X, Reginato MJ, Andrews NC, Lazar MA (1997) The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2. Mol Cell Biol 17:1407-1416.
    • (1997) Mol Cell Biol , vol.17 , pp. 1407-1416
    • Cheng, X.1    Reginato, M.J.2    Andrews, N.C.3    Lazar, M.A.4
  • 27
    • 0035815647 scopus 로고    scopus 로고
    • Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation
    • Hung HL, Kim AY, Hong W, Rakowski C, Blobel GA (2001) Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation. J Biol Chem 276:10715-10721.
    • (2001) J Biol Chem , vol.276 , pp. 10715-10721
    • Hung, H.L.1    Kim, A.Y.2    Hong, W.3    Rakowski, C.4    Blobel, G.A.5
  • 28
    • 0037317298 scopus 로고    scopus 로고
    • Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1
    • Letting DL, Rakowski C, Weiss MJ, Blobel GA (2003) Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Mol Cell Biol 23:1334-1340.
    • (2003) Mol Cell Biol , vol.23 , pp. 1334-1340
    • Letting, D.L.1    Rakowski, C.2    Weiss, M.J.3    Blobel, G.A.4
  • 29
    • 28044437502 scopus 로고    scopus 로고
    • Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region
    • Im H, et al. (2005) Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region. Proc Natl Acad Sci USA 102:17065-17070.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 17065-17070
    • Im, H.1
  • 30
    • 34447536151 scopus 로고    scopus 로고
    • Beta-globin active chromatin hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice
    • Kooren J, et al. (2007) Beta-globin active chromatin hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice. J Biol Chem 282:16544-16552.
    • (2007) J Biol Chem , vol.282 , pp. 16544-16552
    • Kooren, J.1
  • 32
    • 2342485824 scopus 로고    scopus 로고
    • Does looping and clustering in the nucleus regulate gene expression?
    • Chambeyron S, Bickmore WA (2004) Does looping and clustering in the nucleus regulate gene expression? Curr Opin Cell Biol 16:256-262.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 256-262
    • Chambeyron, S.1    Bickmore, W.A.2
  • 33
    • 33748432578 scopus 로고    scopus 로고
    • Transcriptional control thrown for a loop
    • Fraser P (2006) Transcriptional control thrown for a loop. Curr Opin Genet Dev 16:490-495.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 490-495
    • Fraser, P.1
  • 34
    • 13444250972 scopus 로고    scopus 로고
    • Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer
    • Ameres SL, et al. (2005) Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer. EMBO J 24:358-367.
    • (2005) EMBO J , vol.24 , pp. 358-367
    • Ameres, S.L.1
  • 35
    • 0141514008 scopus 로고    scopus 로고
    • Rationally designed insulator-like elements can block enhancer action in vitro
    • Bondarenko VA, Jiang YI, Studitsky VM (2003) Rationally designed insulator-like elements can block enhancer action in vitro. EMBO J 22:4728-4737.
    • (2003) EMBO J , vol.22 , pp. 4728-4737
    • Bondarenko, V.A.1    Jiang, Y.I.2    Studitsky, V.M.3
  • 36
    • 38649128173 scopus 로고    scopus 로고
    • Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus
    • Jing H, et al. (2008) Exchange of GATA factors mediates transitions in looped chromatin organization at a developmentally regulated gene locus. Mol Cell 29:232-242.
    • (2008) Mol Cell , vol.29 , pp. 232-242
    • Jing, H.1
  • 37
    • 38849121606 scopus 로고    scopus 로고
    • Cohesins functionally associate with CTCF on mammalian chromosome arms
    • Parelho V, et al. (2008) Cohesins functionally associate with CTCF on mammalian chromosome arms. Cell 132:422-433.
    • (2008) Cell , vol.132 , pp. 422-433
    • Parelho, V.1
  • 38
    • 39149121436 scopus 로고    scopus 로고
    • Cohesin mediates transcriptional insulation by CCCTC-binding factor
    • Wendt KS, et al. (2008) Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature 451:796-801.
    • (2008) Nature , vol.451 , pp. 796-801
    • Wendt, K.S.1
  • 39
    • 39449111307 scopus 로고    scopus 로고
    • Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators
    • Stedman W, et al. (2008) Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators. EMBO J 27:654-666.
    • (2008) EMBO J , vol.27 , pp. 654-666
    • Stedman, W.1
  • 40
    • 33947201809 scopus 로고    scopus 로고
    • Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome
    • Kim TH, et al. (2007) Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome. Cell 128:1231-1245.
    • (2007) Cell , vol.128 , pp. 1231-1245
    • Kim, T.H.1
  • 41
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • Barski A, et al. (2007) High-resolution profiling of histone methylations in the human genome. Cell 129:823-837.
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1
  • 42
    • 0033936743 scopus 로고    scopus 로고
    • Functional gene expression domains: Defining the functional unit of eukaryotic gene regulation
    • Dillon N, Sabbattini P (2000) Functional gene expression domains: defining the functional unit of eukaryotic gene regulation. Bioessays 22:657-665.
    • (2000) Bioessays , vol.22 , pp. 657-665
    • Dillon, N.1    Sabbattini, P.2
  • 43
    • 36749056884 scopus 로고    scopus 로고
    • A positive role for NLI/Ldb1 in long-range β-globin locus control region function
    • Song S-H, Hou C, Dean A (2007) A positive role for NLI/Ldb1 in long-range β-globin locus control region function. Mol Cell 28:810-822.
    • (2007) Mol Cell , vol.28 , pp. 810-822
    • Song, S.-H.1    Hou, C.2    Dean, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.