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Volumn 24, Issue 2, 2005, Pages 358-367

Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer

Author keywords

Conditional gene regulation; Dimerizer; DNA loop formation; SV40 enhancer; Tet

Indexed keywords

ARTICLE; COVALENT BOND; DNA STRUCTURE; EFFECTOR CELL; ENHANCER REGION; GENE CONTROL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE INDUCTION; GENETIC TRANSCRIPTION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MODIFICATION; SIMIAN VIRUS 40; TRANSACTIVATION; TRANSCRIPTION REGULATION;

EID: 13444250972     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600531     Document Type: Article
Times cited : (39)

References (40)
  • 1
    • 0033514374 scopus 로고    scopus 로고
    • Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes
    • Baron U, Schnappinger D, Helbl V, Gossen M, Hillen W, Bujard H (1999) Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes. Proc Natl Acad Sci USA 96: 1013-1018
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1013-1018
    • Baron, U.1    Schnappinger, D.2    Helbl, V.3    Gossen, M.4    Hillen, W.5    Bujard, H.6
  • 2
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
    • Bell AC, West AG, Felsenfeld G (1999) The protein CTCF is required for the enhancer blocking activity of vertebrate insulators. Cell 98: 387-396
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 3
    • 0042268512 scopus 로고    scopus 로고
    • Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes
    • Berens C, Hillen W (2003) Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes. Eur J Biochem 270: 3109-3121
    • (2003) Eur J Biochem , vol.270 , pp. 3109-3121
    • Berens, C.1    Hillen, W.2
  • 4
    • 0029415181 scopus 로고
    • Deletion mutagenesis of Tn10 Tet repressor localization of regions important for dimerization and inducibility in vivo
    • Berens C, Pfleiderer K, Helbl V, Hillen W (1995) Deletion mutagenesis of Tn10 Tet repressor localization of regions important for dimerization and inducibility in vivo. Mol Microbiol 18: 437-448
    • (1995) Mol Microbiol , vol.18 , pp. 437-448
    • Berens, C.1    Pfleiderer, K.2    Helbl, V.3    Hillen, W.4
  • 5
    • 0032479079 scopus 로고    scopus 로고
    • Going the distance: A current view of enhancer action
    • Blackwood EM, Kadonaga JT (1998) Going the distance: a current view of enhancer action. Science 281: 60-63
    • (1998) Science , vol.281 , pp. 60-63
    • Blackwood, E.M.1    Kadonaga, J.T.2
  • 6
    • 0037338603 scopus 로고    scopus 로고
    • Proteimprotein interactions and the pairing of boundary elements in vivo
    • Blanton J, Gaszner M, Schedl P (2003) Proteimprotein interactions and the pairing of boundary elements in vivo. Genes Dev 17: 664-675
    • (2003) Genes Dev , vol.17 , pp. 664-675
    • Blanton, J.1    Gaszner, M.2    Schedl, P.3
  • 7
    • 0141514008 scopus 로고    scopus 로고
    • Rationally designed insulator-like elements can block enhancer action in vitro
    • Bondarenko VA, Jiang YI, Studitsky VM (2003) Rationally designed insulator-like elements can block enhancer action in vitro. EMBO J 22: 4728-4737
    • (2003) EMBO J , vol.22 , pp. 4728-4737
    • Bondarenko, V.A.1    Jiang, Y.I.2    Studitsky, V.M.3
  • 8
    • 0019586165 scopus 로고
    • Mechanism of action of the lexA gene product
    • Brent R, Ptashne M (1981) Mechanism of action of the lexA gene product. Proc Natl Acad Sci USA 78: 4204-4208
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 4204-4208
    • Brent, R.1    Ptashne, M.2
  • 9
    • 2342485824 scopus 로고    scopus 로고
    • Does looping and clustering in the nucleus regulate gene expression?
    • Chambeyron S, Bickmore WA (2004) Does looping and clustering in the nucleus regulate gene expression? Curr Opin Cell Biol 16: 256-262
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 256-262
    • Chambeyron, S.1    Bickmore, W.A.2
  • 10
    • 0036169663 scopus 로고    scopus 로고
    • A system for small-molecule control of conditionally replication- competent adenoviral vectors
    • Chong H, Ruchatz A, Clackson T, Rivera VM, Vile RG (2002) A system for small-molecule control of conditionally replication-competent adenoviral vectors. Mol Ther 5: 195-203
    • (2002) Mol Ther , vol.5 , pp. 195-203
    • Chong, H.1    Ruchatz, A.2    Clackson, T.3    Rivera, V.M.4    Vile, R.G.5
  • 12
    • 0027254748 scopus 로고
    • A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila
    • Chung JH, Whiteley M, Felsenfeld G (1993) A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74: 505-514
    • (1993) Cell , vol.74 , pp. 505-514
    • Chung, J.H.1    Whiteley, M.2    Felsenfeld, G.3
  • 13
    • 0031033367 scopus 로고    scopus 로고
    • The activity of the scs and scs' insulator elements is not dependent on chromosomal context
    • Dunaway M, Hwang JY, Xiong M, Yuen HL (1997) The activity of the scs and scs' insulator elements is not dependent on chromosomal context. Mol Cell Biol 17: 182-189
    • (1997) Mol Cell Biol , vol.17 , pp. 182-189
    • Dunaway, M.1    Hwang, J.Y.2    Xiong, M.3    Yuen, H.L.4
  • 15
    • 0037195153 scopus 로고    scopus 로고
    • Interphase chromosomes in Arabidopsis are organized as well defined chromocenters from which euchromatin loops emanate
    • Fransz P, De Jong JH, Lysak M, Castiglione MR, Schubert I (2002) Interphase chromosomes in Arabidopsis are organized as well defined chromocenters from which euchromatin loops emanate. Proc Natl Acad Sci USA 99: 14584-14589
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14584-14589
    • Fransz, P.1    De Jong, J.H.2    Lysak, M.3    Castiglione, M.R.4    Schubert, I.5
  • 16
    • 0032548927 scopus 로고    scopus 로고
    • Polycomb and trithorax group proteins mediate the function of a chromatin insulator
    • Gerasimova TI, Corces VG (1998) Polycomb and trithorax group proteins mediate the function of a chromatin insulator. Cell 92: 511-521
    • (1998) Cell , vol.92 , pp. 511-521
    • Gerasimova, T.I.1    Corces, V.G.2
  • 17
    • 0035671406 scopus 로고    scopus 로고
    • Chromatin insulators and boundaries: Effects on transcription and nuclear organization
    • Gerasimova TI, Corces VG (2001) Chromatin insulators and boundaries: effects on transcription and nuclear organization. Annu Rev Genet 35: 193-208
    • (2001) Annu Rev Genet , vol.35 , pp. 193-208
    • Gerasimova, T.I.1    Corces, V.G.2
  • 18
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89: 5547-5551
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 20
    • 3242701306 scopus 로고    scopus 로고
    • Structure-based design of Tet repressor to optimize a new inducer specificity
    • Henssler EM, Scholz O, Lochner S, Gmeiner P, Hillen W (2004) Structure-based design of Tet repressor to optimize a new inducer specificity. Biochemistry 43: 9512-9518
    • (2004) Biochemistry , vol.43 , pp. 9512-9518
    • Henssler, E.M.1    Scholz, O.2    Lochner, S.3    Gmeiner, P.4    Hillen, W.5
  • 21
    • 0026100193 scopus 로고
    • Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster
    • Holdridge C, Dorsett D (1991) Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogaster. Mol Cell Biol 11: 1894-1900
    • (1991) Mol Cell Biol , vol.11 , pp. 1894-1900
    • Holdridge, C.1    Dorsett, D.2
  • 22
    • 0025598302 scopus 로고
    • Sequence requirements for coiled-coils: Analysis with λ repressor-GCN4 leucine zipper fusions
    • Hu JC, O'Shea EK, Kim PS, Sauer RT (1990) Sequence requirements for coiled-coils: analysis with λ repressor-GCN4 leucine zipper fusions. Science 250: 1400-1403
    • (1990) Science , vol.250 , pp. 1400-1403
    • Hu, J.C.1    O'Shea, E.K.2    Kim, P.S.3    Sauer, R.T.4
  • 23
    • 0003191832 scopus 로고
    • BRL pUC host: E. coli DH5α competent cells
    • Invitrogen (1986) BRL pUC host: E. coli DH5α competent cells. Focus 8: 9
    • (1986) Focus , vol.8 , pp. 9
  • 25
    • 0038022782 scopus 로고    scopus 로고
    • Genomic insulators: Connecting properties to mechanism
    • Kuhn EJ, Geyer PK (2003) Genomic insulators: connecting properties to mechanism. Curr Opin Cell Biol 15: 259-265
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 259-265
    • Kuhn, E.J.1    Geyer, P.K.2
  • 26
  • 27
    • 0037049548 scopus 로고    scopus 로고
    • Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH
    • Mahy NL, Perry PE, Bickmore WA (2002) Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH. J Cell Biol 159: 753-763
    • (2002) J Cell Biol , vol.159 , pp. 753-763
    • Mahy, N.L.1    Perry, P.E.2    Bickmore, W.A.3
  • 28
    • 0037133141 scopus 로고    scopus 로고
    • Structure-based design of a leucine zipper protein with new DNA contacting region
    • Morii T, Sato S, Hagihara M, Mori Y, Imoto K, Makino K (2002) Structure-based design of a leucine zipper protein with new DNA contacting region. Biochemistry 41: 2177-2183
    • (2002) Biochemistry , vol.41 , pp. 2177-2183
    • Morii, T.1    Sato, S.2    Hagihara, M.3    Mori, Y.4    Imoto, K.5    Makino, K.6
  • 29
    • 3543018516 scopus 로고    scopus 로고
    • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops
    • Murrell A, Heeson S, Reik W (2004) Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet 36: 889-893
    • (2004) Nat Genet , vol.36 , pp. 889-893
    • Murrell, A.1    Heeson, S.2    Reik, W.3
  • 30
    • 0032554641 scopus 로고    scopus 로고
    • Kinetic studies of sequence-specific binding of GCN4-bZIP peptides to DNA strands immobilized on a 27-MHz quartz-crystal microbalance
    • Okahata Y, Niikura K, Sugiura Y, Sawada M, Morii T (1998) Kinetic studies of sequence-specific binding of GCN4-bZIP peptides to DNA strands immobilized on a 27-MHz quartz-crystal microbalance. Biochemistry 37: 5666-5672
    • (1998) Biochemistry , vol.37 , pp. 5666-5672
    • Okahata, Y.1    Niikura, K.2    Sugiura, Y.3    Sawada, M.4    Morii, T.5
  • 31
    • 0034087676 scopus 로고    scopus 로고
    • Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system
    • Orth P, Schnappinger D, Hillen W, Saenger W, Hinrichs W (2000) Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nat Struct Biol 7: 215-219
    • (2000) Nat Struct Biol , vol.7 , pp. 215-219
    • Orth, P.1    Schnappinger, D.2    Hillen, W.3    Saenger, W.4    Hinrichs, W.5
  • 32
    • 1842505303 scopus 로고    scopus 로고
    • Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance
    • Pant V, Kurukuti S, Pugacheva E, Shamsuddin S, Mariano P, Renkawitz R, Klenova E, Lobanenkov V, Ohlsson R (2004) Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance. Mol Cell Biol 24: 3497-3504
    • (2004) Mol Cell Biol , vol.24 , pp. 3497-3504
    • Pant, V.1    Kurukuti, S.2    Pugacheva, E.3    Shamsuddin, S.4    Mariano, P.5    Renkawitz, R.6    Klenova, E.7    Lobanenkov, V.8    Ohlsson, R.9
  • 33
    • 0033453222 scopus 로고    scopus 로고
    • Positional enhancer-blocking activity of the chicken β-globin insulator in transiently transfected cells
    • Recillas-Targa F, Bell AC, Felsenfeld G (1999) Positional enhancer-blocking activity of the chicken β-globin insulator in transiently transfected cells. Proc Natl Acad Sci USA 96: 14354-14359
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14354-14359
    • Recillas-Targa, F.1    Bell, A.C.2    Felsenfeld, G.3
  • 34
    • 0035668536 scopus 로고    scopus 로고
    • Making contacts on a nucleic acid polymer
    • Rippe K (2001) Making contacts on a nucleic acid polymer. Trends Biochem Sci 26: 733-740
    • (2001) Trends Biochem Sci , vol.26 , pp. 733-740
    • Rippe, K.1
  • 35
    • 0024277747 scopus 로고
    • The carboxy-terminal domain of the LexA repressor oligomerises essentially as the entire protein
    • Schnarr M, Granger-Schnarr M, Hurstel S, Pouyet J (1988) The carboxy-terminal domain of the LexA repressor oligomerises essentially as the entire protein. FEBS Lett 234: 56-60
    • (1988) FEBS Lett , vol.234 , pp. 56-60
    • Schnarr, M.1    Granger-Schnarr, M.2    Hurstel, S.3    Pouyet, J.4
  • 36
    • 0024366249 scopus 로고
    • Tet repressor binding induced curvature of tet operator DNA
    • Tovar K, Hillen W (1989) Tet repressor binding induced curvature of tet operator DNA. Nucleic Acids Res 17: 6515-6522
    • (1989) Nucleic Acids Res , vol.17 , pp. 6515-6522
    • Tovar, K.1    Hillen, W.2
  • 37
    • 0022178109 scopus 로고
    • The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains
    • Udvardy A, Maine E, Schedl P (1985) The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains. J Mol Biol 185: 341-358
    • (1985) J Mol Biol , vol.185 , pp. 341-358
    • Udvardy, A.1    Maine, E.2    Schedl, P.3
  • 38
    • 0028600559 scopus 로고
    • Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions
    • Vazquez J, Schedl P (1994) Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions. EMBO J 13: 5984-5993
    • (1994) EMBO J , vol.13 , pp. 5984-5993
    • Vazquez, J.1    Schedl, P.2
  • 39
    • 0014588869 scopus 로고
    • Characteristics of some multiply recombination-deficient strains of Escherichia coli
    • Willetts NS, Clark AJ (1969) Characteristics of some multiply recombination-deficient strains of Escherichia coli. J Bacteriol 100: 231-239
    • (1969) J Bacteriol , vol.100 , pp. 231-239
    • Willetts, N.S.1    Clark, A.J.2
  • 40
    • 0842310349 scopus 로고    scopus 로고
    • CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species
    • Yusufzai TM, Tagami H, Nakatani Y, Felsenfeld G (2004) CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species. Mol Cell 13: 291-298
    • (2004) Mol Cell , vol.13 , pp. 291-298
    • Yusufzai, T.M.1    Tagami, H.2    Nakatani, Y.3    Felsenfeld, G.4


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