SCOPUS 정보 검색 플랫폼

Volumn 447, Issue 1, 2002, Pages 37-42

The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injury

(9) Legos, Jeffrey J a McLaughlin, BethAnn b Skaper, Stephen D c Strijbos, Paul J L M c Parsons, Andrew A c Aizenman, Elias b Herin, Greta A b Barone, Frank C a Erhardt, Joseph A a

a GLAXOSMITHKLINE (United States)

b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE (United States)

c GLAXOSMITHKLINE (United Kingdom)

Author keywords

Acute neuronal injury; Cell culture; Excitotoxicity; Ischemic cell death; Neuroprotection; p38 MAP Kinase

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; AMINO ACID RECEPTOR STIMULATING AGENT; ENZYME INHIBITOR; GLUCOSE; IMIDAZOLE DERIVATIVE; MAGNESIUM; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT; PYRIMIDINE DERIVATIVE; 1 (4 HYDROXYCYCLOHEXYL) 4 (FLUOROPHENYL) 5 (2 METHOXY PYRIMIDIN 4 YL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; N METHYL DEXTRO ASPARTIC ACID; OXYGEN; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; CELL CULTURE; CELL DEATH; CELL HYPOXIA; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FOREBRAIN; HIPPOCAMPUS; METABOLISM; NERVE CELL; PATCH CLAMP; PHYSIOLOGY; RAT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; DRUG SELECTIVITY; ELECTROPHYSIOLOGY; ENZYME ACTIVITY; FETUS; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; TOXICITY;

ANIMALS; CELL DEATH; CELL HYPOXIA; CELLS, CULTURED; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; GLUCOSE; HIPPOCAMPUS; IMIDAZOLES; MAGNESIUM; MITOGEN-ACTIVATED PROTEIN KINASES; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PATCH-CLAMP TECHNIQUES; PROSENCEPHALON; PYRIMIDINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; ANIMAL;

EID: 0037188746 PISSN: 00142999 EISSN: None Source Type: Journal
DOI: 10.1016/S0014-2999(02)01890-3 Document Type: Article

Times cited : (60)

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