Deletion of inducible nitric oxide synthase provides cardioprotection in mice with 2-kidney, 1-clip hypertension

Hypertension

Volumn 53, Issue 1, 2009, Pages 49-56

  Sun, Ying ^a,b   Carretero, Oscar A ^a   Xu, Jiang ^a   Rhaleb, Nour Eddine ^a   Yang, James J ^a   Pagano, Patrick J ^a   Yang, Xiao Ping ^a,c  

^a HENRY FORD HOSPITAL   (United States)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac function; DOCA salt hypertension; NO synthase; Oxidative stress

Indexed keywords

ANGIOTENSIN I; ANGIOTENSINOGEN; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DEOXYCORTICOSTERONE ACETATE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; ISOPRENALINE; NITRATE; NITRITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RENIN; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPPLER ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART PROTECTION; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SYSTOLIC BLOOD PRESSURE; URINE LEVEL; WESTERN BLOTTING; ANIMAL; BLOOD; BLOOD PRESSURE; C57BL MOUSE; DISEASE MODEL; FIBROSIS; GENE DELETION; GENETICS; HEART MUSCLE; METABOLISM; MOUSE MUTANT; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; RENOVASCULAR HYPERTENSION; SURGICAL INSTRUMENT; URINE;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; FIBROSIS; GENE DELETION; HYPERTENSION, RENOVASCULAR; HYPERTROPHY, LEFT VENTRICULAR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOCARDIUM; NITRATES; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; ORGAN SIZE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RENIN; SURGICAL INSTRUMENTS;

EID: 58149401216     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.108.121822     Document Type: Article

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