메뉴 건너뛰기




Volumn 66, Issue 1, 2009, Pages 24-35

Functional studies of an evolutionary conserved, cytochrome b5 domain protein reveal a specific role in axonemal organisation and the general phenomenon of post-division axonemal growth in trypanosomes

Author keywords

Central pair; Flagellum; RNAi; Trypanosome

Indexed keywords

CYTOCHROME B5; HYBRID PROTEIN; PROTEIN; RNA; TRYPANOSOME AXONEMAL 2 PROTEIN; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; PROTOZOAL PROTEIN;

EID: 58149354852     PISSN: 08861544     EISSN: 10970169     Source Type: Journal    
DOI: 10.1002/cm.20322     Document Type: Article
Times cited : (26)

References (42)
  • 2
    • 55849123576 scopus 로고    scopus 로고
    • Absalon S, Kohl L, Branche C, Blisnick T, Toutirais G, Rusconi F, Cosson J, Bonhivers M, Robinson D, Bastin P. 2007. Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. PLoSONE 2:e437.
    • Absalon S, Kohl L, Branche C, Blisnick T, Toutirais G, Rusconi F, Cosson J, Bonhivers M, Robinson D, Bastin P. 2007. Basal body positioning is controlled by flagellum formation in Trypanosoma brucei. PLoSONE 2:e437.
  • 4
    • 0034649566 scopus 로고    scopus 로고
    • Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
    • Arabidopsis Genome Initiative
    • Arabidopsis Genome Initiative. 2000. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature 408:796-815.
    • (2000) Nature , vol.408 , pp. 796-815
  • 5
    • 0016590744 scopus 로고
    • The structure of ferrocytochrome b5 at 2.8 A resolution
    • Argos P. Mathews FS. 1975. The structure of ferrocytochrome b5 at 2.8 A resolution. J Biol Chem 250:747-751.
    • (1975) J Biol Chem , vol.250 , pp. 747-751
    • Argos, P.1    Mathews, F.S.2
  • 8
    • 34249650299 scopus 로고    scopus 로고
    • Stuck in reverse: Loss of LC1 in Trypanosoma brucei disrupts outer dynein arms and leads to reverse flagellar beat and backward movement
    • Baron DM, Kabututu ZP, Hill KL. 2007a. Stuck in reverse: loss of LC1 in Trypanosoma brucei disrupts outer dynein arms and leads to reverse flagellar beat and backward movement. J Cell Sci 120 (Pt 9): 1513-1520.
    • (2007) J Cell Sci , vol.120 , Issue.PART 9 , pp. 1513-1520
    • Baron, D.M.1    Kabututu, Z.P.2    Hill, K.L.3
  • 9
    • 33847370317 scopus 로고    scopus 로고
    • Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella
    • Baron DM. Ralston KS, Kabututu ZP, Hill KL. 2007b. Functional genomics in Trypanosoma brucei identifies evolutionarily conserved components of motile flagella. J Cell Sci 120(Part 3): 478-491.
    • (2007) J Cell Sci , vol.120 , Issue.PART 3 , pp. 478-491
    • Baron, D.M.1    Ralston, K.S.2    Kabututu, Z.P.3    Hill, K.L.4
  • 10
    • 0032484944 scopus 로고    scopus 로고
    • Paraflagellar rod is vital for trypanosome motility
    • Bastin P, Sherwin T, Gull K. 1998. Paraflagellar rod is vital for trypanosome motility. Nature 391:548.
    • (1998) Nature , vol.391 , pp. 548
    • Bastin, P.1    Sherwin, T.2    Gull, K.3
  • 11
    • 33748759561 scopus 로고    scopus 로고
    • Conserved and specific functions of axoneme components in trypanosome motility
    • Branche C, Kohl L, Toutirais G, Buisson J, Cosson J, Bastin P. 2006. Conserved and specific functions of axoneme components in trypanosome motility. J Cell Sci 119(Part 16):3443-3455.
    • (2006) J Cell Sci , vol.119 , Issue.PART 16 , pp. 3443-3455
    • Branche, C.1    Kohl, L.2    Toutirais, G.3    Buisson, J.4    Cosson, J.5    Bastin, P.6
  • 12
    • 4143126756 scopus 로고    scopus 로고
    • More than one way to build a flagellum: Comparative genomics of parasitic protozoa
    • Briggs LJ, Davidge JA, Wickstead B, Ginger ML, Gull K. 2004. More than one way to build a flagellum: comparative genomics of parasitic protozoa. Curr Biol 14:R611-R612.
    • (2004) Curr Biol , vol.14
    • Briggs, L.J.1    Davidge, J.A.2    Wickstead, B.3    Ginger, M.L.4    Gull, K.5
  • 14
    • 0017467555 scopus 로고
    • A new semi-defined medium for Trypanosoma brucei sspp
    • Brun R, Jenni L. 1977. A new semi-defined medium for Trypanosoma brucei sspp. Acta Trop 34:21-33.
    • (1977) Acta Trop , vol.34 , pp. 21-33
    • Brun, R.1    Jenni, L.2
  • 15
    • 33750444557 scopus 로고    scopus 로고
    • Trypanosome IPT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formation
    • Davidge JA, Chambers E, Dickinson HA, Towers K, Ginger ML. McKean PG, Gull K. 2006. Trypanosome IPT mutants provide insight into the motor location for mobility of the flagella connector and flagellar membrane formation. J Cell Sci 119(Part 19):3935-3943.
    • (2006) J Cell Sci , vol.119 , Issue.PART 19 , pp. 3935-3943
    • Davidge, J.A.1    Chambers, E.2    Dickinson, H.A.3    Towers, K.4    Ginger, M.L.5    McKean, P.G.6    Gull, K.7
  • 16
    • 30544436017 scopus 로고    scopus 로고
    • The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet micro-tubule morphogenesis
    • Dawe HR, Farr H, Portman N, Shaw MK, Gull K. 2005. The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet micro-tubule morphogenesis. J Cell Sci 118(Part 23):5421-5430.
    • (2005) J Cell Sci , vol.118 , Issue.PART 23 , pp. 5421-5430
    • Dawe, H.R.1    Farr, H.2    Portman, N.3    Shaw, M.K.4    Gull, K.5
  • 20
    • 33746092106 scopus 로고    scopus 로고
    • Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes
    • Gadelha C, Wickstead B, McKean PG, Gull K. 2006. Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axonemes of trypanosomes. J Cell Sci 119(Part 12):2405-2413.
    • (2006) J Cell Sci , vol.119 , Issue.PART 12 , pp. 2405-2413
    • Gadelha, C.1    Wickstead, B.2    McKean, P.G.3    Gull, K.4
  • 22
    • 0031871382 scopus 로고    scopus 로고
    • Cloning and tissue expression of two putative steroid membrane receptors
    • Gerdes D, Wehling M, Leube B, Falkenstein E. 1998. Cloning and tissue expression of two putative steroid membrane receptors. Biol Chem 379:907-911.
    • (1998) Biol Chem , vol.379 , pp. 907-911
    • Gerdes, D.1    Wehling, M.2    Leube, B.3    Falkenstein, E.4
  • 23
    • 34447572946 scopus 로고    scopus 로고
    • RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection
    • Griffiths S, Portman N, Taylor PR, Gordon S, Ginger ML, Gull K. 2007. RNA interference mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection. Eukaryot Cell 6:1248-1250.
    • (2007) Eukaryot Cell , vol.6 , pp. 1248-1250
    • Griffiths, S.1    Portman, N.2    Taylor, P.R.3    Gordon, S.4    Ginger, M.L.5    Gull, K.6
  • 24
    • 0024948840 scopus 로고
    • Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
    • Hirumi H, Hirumi K. 1989. Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J Parasitol 75:985-989.
    • (1989) J Parasitol , vol.75 , pp. 985-989
    • Hirumi, H.1    Hirumi, K.2
  • 25
    • 0037018159 scopus 로고    scopus 로고
    • Trypanin is a cytoskeletal linker protein and is required for cell motility in African trypanosomes
    • Hutchings NR, Donelson JE, Hill KL. 2002. Trypanin is a cytoskeletal linker protein and is required for cell motility in African trypanosomes. J Cell Biol 156:867-877.
    • (2002) J Cell Biol , vol.156 , pp. 867-877
    • Hutchings, N.R.1    Donelson, J.E.2    Hill, K.L.3
  • 30
    • 0037380134 scopus 로고    scopus 로고
    • Gamma-tubulin functions in the nucleation of a discrete subset of microtubules in the eukaryotic flagellum
    • McKean PG, Baines A, Vaughan S, Gull K. 2003. Gamma-tubulin functions in the nucleation of a discrete subset of microtubules in the eukaryotic flagellum. Curr Biol 13:598-602.
    • (2003) Curr Biol , vol.13 , pp. 598-602
    • McKean, P.G.1    Baines, A.2    Vaughan, S.3    Gull, K.4
  • 32
    • 33749528009 scopus 로고    scopus 로고
    • Trypanin, a component of the flagellar dynein regulatory complex, is essential in bloodstream form African trypanosomes
    • Ralston KS, Hill KL, 2006, Trypanin, a component of the flagellar dynein regulatory complex, is essential in bloodstream form African trypanosomes. PLoS Pathog 2:e101.
    • (2006) PLoS Pathog , vol.2
    • Ralston, K.S.1    Hill, K.L.2
  • 33
    • 0037306331 scopus 로고    scopus 로고
    • The many roles of cytochrome b5
    • Schenkman JB, Jansson I. 2003, The many roles of cytochrome b5. Pharmacol Ther 97:139-152.
    • (2003) Pharmacol Ther , vol.97 , pp. 139-152
    • Schenkman, J.B.1    Jansson, I.2
  • 34
    • 0024967876 scopus 로고
    • The cell division cycle of Trypanosoma brucei brucei: Timing of event markers and cytoskeletal modulations
    • Sherwin T, Gull K. 1989. The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations. Philos Trans R Soc Lond B Biol Sci 323:573-588.
    • (1989) Philos Trans R Soc Lond B Biol Sci , vol.323 , pp. 573-588
    • Sherwin, T.1    Gull, K.2
  • 35
    • 14844346387 scopus 로고    scopus 로고
    • Genomewide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes
    • Stole V, Samanta MP, Tongprasit W, Marshall WF. 2005. Genomewide transcriptional analysis of flagellar regeneration in Chlamydomonas reinhardtii identifies orthologs of ciliary disease genes. Proc Natl Acad Sci USA 102:3703-3707.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3703-3707
    • Stole, V.1    Samanta, M.P.2    Tongprasit, W.3    Marshall, W.F.4
  • 36
    • 0032509302 scopus 로고    scopus 로고
    • The C. elegans Sequencing Consortium, 1998. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282:2012-2018.
    • The C. elegans Sequencing Consortium, 1998. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282:2012-2018.
  • 37
    • 0031574072 scopus 로고    scopus 로고
    • The CLUSTAL-X windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
    • Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. 1997, The CLUSTAL-X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 25:4876-4882.
    • (1997) Nucleic Acids Res , vol.25 , pp. 4876-4882
    • Thompson, J.D.1    Gibson, T.J.2    Plewniak, F.3    Jeanmougin, F.4    Higgins, D.G.5
  • 38
    • 0036860235 scopus 로고    scopus 로고
    • Targeting of a tetracycline- inducible expression system to the transcriptionally silent mini-chromosomes of Trypanosoma brucei
    • Wickstead B, Ersfeld K, Gull K. 2002. Targeting of a tetracycline- inducible expression system to the transcriptionally silent mini-chromosomes of Trypanosoma brucei. Mol Biochem Parasitol 125:211-216.
    • (2002) Mol Biochem Parasitol , vol.125 , pp. 211-216
    • Wickstead, B.1    Ersfeld, K.2    Gull, K.3
  • 39
    • 0242617271 scopus 로고
    • Dynamics of microbial populations
    • Patten B, editor, New York: Academic press, pp
    • Williams FM. 1971, Dynamics of microbial populations. In: Patten B, editor. Systems Analysis and Simulation Ecology. New York: Academic press, pp 247-262.
    • (1971) Systems Analysis and Simulation Ecology , pp. 247-262
    • Williams, F.M.1
  • 40
    • 0033525524 scopus 로고    scopus 로고
    • A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei
    • Wirtz E, Leal S, Ochatt C, Cross GA. 1999. A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei, Mol Biochem Parasitol 99:89-101.
    • (1999) Mol Biochem Parasitol , vol.99 , pp. 89-101
    • Wirtz, E.1    Leal, S.2    Ochatt, C.3    Cross, G.A.4
  • 42
    • 0025061165 scopus 로고
    • Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei
    • Woodward R, Gull K. 1990. Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci 95(Part 1):49-57.
    • (1990) J Cell Sci , vol.95 , Issue.PART 1 , pp. 49-57
    • Woodward, R.1    Gull, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.