-
1
-
-
2942615282
-
Polo-like kinases and the orchestration of cell division
-
Barr FA, Silljé HH, Nigg EA. (2004). Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol 5: 429-440.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 429-440
-
-
Barr, F.A.1
Silljé, H.H.2
Nigg, E.A.3
-
2
-
-
0037434841
-
Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxolor 2-methoxyestradiol- induced apoptosis
-
Basu A, Haldar S. (2003). Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxolor 2-methoxyestradiol- induced apoptosis. FEBS Lett 538: 41-47.
-
(2003)
FEBS Lett
, vol.538
, pp. 41-47
-
-
Basu, A.1
Haldar, S.2
-
3
-
-
0027282044
-
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise LH, González-García M, Postema CE, Ding L, Lindsten T, Turka LA et al. (1993). bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74: 597-608.
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
González-García, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
-
5
-
-
0031918223
-
BCL-2 family: Regulators of cell death
-
Chao DT, Korsmeyer SJ. (1998). BCL-2 family: regulators of cell death. Annu Rev Immunol 16: 395-419.
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
6
-
-
33745133669
-
Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation
-
Chen J, Dai G, Wang YQ, Wang S, Pan FY, Xue B et al. (2006). Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation. FEBS Lett 580: 3626-3630.
-
(2006)
FEBS Lett
, vol.580
, pp. 3626-3630
-
-
Chen, J.1
Dai, G.2
Wang, Y.Q.3
Wang, S.4
Pan, F.Y.5
Xue, B.6
-
9
-
-
0036716281
-
The BCL2 family: Regulators of the cellular life-or-death switch
-
Cory S, Adams JM. (2002). The BCL2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2: 647-656.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.M.2
-
11
-
-
12444306413
-
Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: Evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction
-
Du L, Lyle CS, Chambers TC. (2005). Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction. Oncogene 24: 107-117.
-
(2005)
Oncogene
, vol.24
, pp. 107-117
-
-
Du, L.1
Lyle, C.S.2
Chambers, T.C.3
-
12
-
-
10744221449
-
The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain
-
Elia AE, Rellos P, Haire LF, Chao JW, Ivins FJ, Hoepker K et al. (2003). The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain. Cell 115: 83-95.
-
(2003)
Cell
, vol.115
, pp. 83-95
-
-
Elia, A.E.1
Rellos, P.2
Haire, L.F.3
Chao, J.W.4
Ivins, F.J.5
Hoepker, K.6
-
13
-
-
0033561274
-
Association of polo-like kinase with α-, β- and γ-tubulins in a stable complex
-
Feng Y, Hodge DR, Palmieri G, Chase DL, Longo DL, Ferris DK. (1999). Association of polo-like kinase with α-, β- and γ-tubulins in a stable complex. Biochem J 339: 435-442.
-
(1999)
Biochem J
, vol.339
, pp. 435-442
-
-
Feng, Y.1
Hodge, D.R.2
Palmieri, G.3
Chase, D.L.4
Longo, D.L.5
Ferris, D.K.6
-
14
-
-
17644368237
-
ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent
-
Gumireddy K, Reddy MV, Cosenza SC, Nathan RB, Baker SJ, Papathi N et al. (2005). ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell 7: 275-286.
-
(2005)
Cancer Cell
, vol.7
, pp. 275-286
-
-
Gumireddy, K.1
Reddy, M.V.2
Cosenza, S.C.3
Nathan, R.B.4
Baker, S.J.5
Papathi, N.6
-
15
-
-
2942625430
-
L sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers
-
L sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers. EMBO J 23: 2146-2155.
-
(2004)
EMBO J
, vol.23
, pp. 2146-2155
-
-
Jeong, S.Y.1
Gaume, B.2
Lee, Y.J.3
Hsu, Y.T.4
Ryu, S.W.5
Yoon, S.H.6
-
16
-
-
0037421190
-
L, but not Bcl-2, to the mitochondrial outer membrane
-
L, but not Bcl-2, to the mitochondrial outer membrane. J Cell Biol 160: 53-64.
-
(2003)
J Cell Biol
, vol.160
, pp. 53-64
-
-
Kaufmann, T.1
Schlipf, S.2
Sanz, J.3
Neubert, K.4
Stein, R.5
Borner, C.6
-
17
-
-
0038165498
-
Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion
-
Kawatani M, Imoto M. (2003). Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion. J Biol Chem 278: 19732-19742.
-
(2003)
J Biol Chem
, vol.278
, pp. 19732-19742
-
-
Kawatani, M.1
Imoto, M.2
-
18
-
-
0033152543
-
Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin
-
Kondoh M, Usui T, Nishikiori T, Mayumi T, Osada H. (1999). Apoptosis induction via microtubule disassembly by an antitumour compound, pironetin. Biochem J 340: 411-416.
-
(1999)
Biochem J
, vol.340
, pp. 411-416
-
-
Kondoh, M.1
Usui, T.2
Nishikiori, T.3
Mayumi, T.4
Osada, H.5
-
19
-
-
0038624074
-
Polo-like kinase (Plk) 1 depletion induces apoptosis in cancer cells
-
Liu X, Erikson RL. (2003). Polo-like kinase (Plk) 1 depletion induces apoptosis in cancer cells. Proc Natl Acad Sci USA 100: 5789-5794.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5789-5794
-
-
Liu, X.1
Erikson, R.L.2
-
20
-
-
5244224827
-
L, an inhibitor of programmed cell death
-
L, an inhibitor of programmed cell death. Nature 381: 335-341.
-
(1996)
Nature
, vol.381
, pp. 335-341
-
-
Muchmore, S.W.1
Sattler, M.2
Liang, H.3
Meadows, R.P.4
Harlan, J.E.5
Yoon, H.S.6
-
21
-
-
0038492408
-
Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate
-
Nakajima H, Toyoshima-Morimoto F, Taniguchi E, Nishida E. (2003). Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate. J Biol Chem 278: 25277-25280.
-
(2003)
J Biol Chem
, vol.278
, pp. 25277-25280
-
-
Nakajima, H.1
Toyoshima-Morimoto, F.2
Taniguchi, E.3
Nishida, E.4
-
22
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA et al. (2005). An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435: 677-681.
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
-
25
-
-
0346733235
-
Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1
-
Ree AH, Bratland Å, Nome RV, Stokke T, Fodstad Ø. (2003). Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1. Oncogene 22: 8952-8955.
-
(2003)
Oncogene
, vol.22
, pp. 8952-8955
-
-
Ree, A.H.1
Bratland, A.2
Nome, R.V.3
Stokke, T.4
Fodstad, Ø.5
-
26
-
-
0036463649
-
Apoptosis-based therapies
-
Reed JC. (2002). Apoptosis-based therapies. Nat Rev Drug Discov 1: 111-121.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 111-121
-
-
Reed, J.C.1
-
27
-
-
1442359881
-
Bcl-2 family members: Intracellular targeting, membrane-insertion, and changes in subcellular localization
-
Schinzel A, Kaufmann T, Borner C. (2004). Bcl-2 family members: intracellular targeting, membrane-insertion, and changes in subcellular localization. Biochim Biophys Acta 1644: 95-105.
-
(2004)
Biochim Biophys Acta
, vol.1644
, pp. 95-105
-
-
Schinzel, A.1
Kaufmann, T.2
Borner, C.3
-
28
-
-
0033778278
-
Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines
-
Simizu S, Osada H. (2000). Mutations in the Plk gene lead to instability of Plk protein in human tumour cell lines. Nat Cell Biol 2: 852-854.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 852-854
-
-
Simizu, S.1
Osada, H.2
-
29
-
-
23844508415
-
RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines
-
Simizu S, Takagi S, Tamura Y, Osada H. (2005). RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines. Cancer Res 65: 7455-7461.
-
(2005)
Cancer Res
, vol.65
, pp. 7455-7461
-
-
Simizu, S.1
Takagi, S.2
Tamura, Y.3
Osada, H.4
-
30
-
-
1842866996
-
Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance
-
Simizu S, Tamura Y, Osada H. (2004). Dephosphorylation of Bcl-2 by protein phosphatase 2A results in apoptosis resistance. Cancer Sci 95: 266-270.
-
(2004)
Cancer Sci
, vol.95
, pp. 266-270
-
-
Simizu, S.1
Tamura, Y.2
Osada, H.3
-
31
-
-
3042549655
-
The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria
-
Tamura Y, Simizu S, Osada H. (2004). The phosphorylation status and anti-apoptotic activity of Bcl-2 are regulated by ERK and protein phosphatase 2A on the mitochondria. FEBS Lett 569: 249-255.
-
(2004)
FEBS Lett
, vol.569
, pp. 249-255
-
-
Tamura, Y.1
Simizu, S.2
Osada, H.3
-
32
-
-
0033971901
-
Bcl-2 family: Life-or-death switch
-
Tsujimoto Y, Shimizu S. (2000). Bcl-2 family: life-or-death switch. FEBS Lett 466: 6-10.
-
(2000)
FEBS Lett
, vol.466
, pp. 6-10
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
33
-
-
3042686764
-
The anticancer natural product pironetin selectively targets Lys352 of α-tubulin
-
Usui T, Watanabe H, Nakayama H, Tada Y, Kanoh N, Kondoh M et al. (2004). The anticancer natural product pironetin selectively targets Lys352 of α-tubulin. Chem Biol 11: 799-806.
-
(2004)
Chem Biol
, vol.11
, pp. 799-806
-
-
Usui, T.1
Watanabe, H.2
Nakayama, H.3
Tada, Y.4
Kanoh, N.5
Kondoh, M.6
-
34
-
-
23844525856
-
Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways
-
Watanabe N, Arai H, Iwasaki J, Shiina M, Ogata K, Hunter T et al. (2005). Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways. Proc Natl Acad Sci USA 102: 11663-11668.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11663-11668
-
-
Watanabe, N.1
Arai, H.2
Iwasaki, J.3
Shiina, M.4
Ogata, K.5
Hunter, T.6
|