Increased diabetes development and decreased function of CD4+CD25+ Treg in the absence of a functional DAP12 adaptor protein

European Journal of Immunology

Volumn 38, Issue 11, 2008, Pages 3191-3199

  Hall, Håkan T L ^a   Sjölin, Hanna ^a   Brauner, Hanna ^a   Tomasello, Elena ^b,c,d   Dalod, Marc ^b,c,d   Vivier, Eric ^b,c,d,e   Höglund, Petter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^c INSERM   (France)

^d CNRS   (France)

^e HÔPITAL DE LA CONCEPTION   (France)

Author keywords

DAP12; Diabetes; Pancreatic lymph nodes; Treg

Indexed keywords

KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; GLYCOPROTEIN P 15095; LYMPHOCYTE ANTIGEN RECEPTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TYROBP PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL ACTIVITY; IMMUNE RESPONSE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; DENDRITIC CELL; IMMUNOLOGY; LYMPH NODE; LYMPHOCYTE ACTIVATION; NONOBESE DIABETIC MOUSE; PANCREAS ISLET; PHYSIOLOGY; T LYMPHOCYTE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD11C; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; ISLETS OF LANGERHANS; LYMPH NODES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NOD; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY;

EID: 58149330299     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838259     Document Type: Article

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