Radiation-Induced Salivary Gland Dysfunction Results From p53-Dependent Apoptosis

International Journal of Radiation Oncology Biology Physics

Volumn 73, Issue 2, 2009, Pages 523-529

  Avila, Jennifer L ^a   Grundmann, Oliver ^a   Burd, Randy ^a   Limesand, Kirsten H ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

Apoptosis; p53; Radiation; Salivary gland dysfunction; Salivary glands

Indexed keywords

AMINO ACIDS; CELL DEATH; DOSIMETRY; IRRADIATION; RADIATION EFFECTS; TRANSCRIPTION;

APOPTOSIS; CONSTITUTIVELY ACTIVES; IN VIVO STUDIES; IN-VIVO; INDUCED APOPTOSIS; KNOCKOUT MOUSE; MEDIATED TRANSCRIPTIONS; NECK CANCERS; P53; PAROTID GLANDS; QUALITY OF LIVES; RADIATION EXPOSURES; SALIVARY FUNCTIONS; SALIVARY GLAND DYSFUNCTION; SALIVARY GLANDS; SECONDARY SIDES; TARGET GENES; TIME POINTS; TRANSGENIC; TRANSGENIC MOUSE;

RADIATION;

COBALT 60; PROTEIN BAX; PROTEIN KINASE B; PROTEIN P53; PUMA PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER RADIOTHERAPY; CONTROLLED STUDY; FEMALE; HEAD AND NECK CANCER; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PAROTID GLAND; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVARY GLAND DISEASE; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENZYME ACTIVATION; FEMALE; GENES, P53; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PAROTID GLAND; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SALIVARY GLANDS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 58149326850     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.09.036     Document Type: Article

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