메뉴 건너뛰기




Volumn 50, Issue 1, 2009, Pages 65-71

Anticonvulsant effects of linolenic acid are unrelated to brain phospholipid cell membrane compositions

Author keywords

Antiepileptic drugs; Epilepsy; Ketogenic diet; Pentylenetetrazol; Polyunsaturated fatty acids; Rat

Indexed keywords

ARACHIDONIC ACID; FATTY ACID; ICOSAPENTAENOIC ACID; KETOCAL; LINOLENIC ACID; PENTETRAZOLE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; UNCLASSIFIED DRUG;

EID: 58149250333     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2008.01723.x     Document Type: Article
Times cited : (32)

References (49)
  • 1
    • 0016332555 scopus 로고
    • An animal model for the ketogenic diet
    • Appleton DB, DeVivo DC. (1974) An animal model for the ketogenic diet. Epilepsia 15 : 211 227.
    • (1974) Epilepsia , vol.15 , pp. 211-227
    • Appleton, D.B.1    Devivo, D.C.2
  • 2
    • 33644811740 scopus 로고    scopus 로고
    • The utility of testing pentylenetetrazol threshold
    • Auvin S, Shin D, Mazarati A, Sankar R. (2006) The utility of testing pentylenetetrazol threshold. Epilepsia 47 : 662 663.
    • (2006) Epilepsia , vol.47 , pp. 662-663
    • Auvin, S.1    Shin, D.2    Mazarati, A.3    Sankar, R.4
  • 3
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ. (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37 : 911 917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 4
    • 0037185379 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids induce ischemic and epileptic tolerance
    • Blondeau N, Widmann C, Lazdunski M, Heurteaux C. (2002) Polyunsaturated fatty acids induce ischemic and epileptic tolerance. Neuroscience 109 : 231 241.
    • (2002) Neuroscience , vol.109 , pp. 231-241
    • Blondeau, N.1    Widmann, C.2    Lazdunski, M.3    Heurteaux, C.4
  • 5
    • 0032901064 scopus 로고    scopus 로고
    • A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat
    • Bough KJ, Eagles DA. (1999) A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. Epilepsia 40 : 138 143.
    • (1999) Epilepsia , vol.40 , pp. 138-143
    • Bough, K.J.1    Eagles, D.A.2
  • 6
    • 0032738404 scopus 로고    scopus 로고
    • Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the rat
    • Bough KJ, Chen RS, Eagles DA. (1999a) Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the rat. Dev Neurosci 21 : 400 406.
    • (1999) Dev Neurosci , vol.21 , pp. 400-406
    • Bough, K.J.1    Chen, R.S.2    Eagles, D.A.3
  • 7
    • 0032902642 scopus 로고    scopus 로고
    • Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet
    • Bough KJ, Valiyil R, Han FT, Eagles DA. (1999b) Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet. Epilepsy Res 35 : 21 28.
    • (1999) Epilepsy Res , vol.35 , pp. 21-28
    • Bough, K.J.1    Valiyil, R.2    Han, F.T.3    Eagles, D.A.4
  • 8
    • 0033992065 scopus 로고    scopus 로고
    • A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion
    • Bough KJ, Matthews PJ, Eagles DA. (2000) A ketogenic diet has different effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion. Epilepsy Res 38 : 105 114.
    • (2000) Epilepsy Res , vol.38 , pp. 105-114
    • Bough, K.J.1    Matthews, P.J.2    Eagles, D.A.3
  • 10
    • 1042265019 scopus 로고    scopus 로고
    • The ketogneic diet: Fatty acids, fatty acid-activated receptors and neurological disorders
    • Cullingford TE. (2004) The ketogneic diet: fatty acids, fatty acid-activated receptors and neurological disorders. Prostaglandins Leukot Essent Fatty Acids 70 : 253 264.
    • (2004) Prostaglandins Leukot Essent Fatty Acids , vol.70 , pp. 253-264
    • Cullingford, T.E.1
  • 11
    • 0035033819 scopus 로고    scopus 로고
    • Lipid and fatty acid profiles in rats consuming different high-fat ketogenic diets
    • Dell CA, Likhodii SS, Musa K, Ryan MA, Burnham WM, Cunnane SC. (2001) Lipid and fatty acid profiles in rats consuming different high-fat ketogenic diets. Lipids 36 : 373 378.
    • (2001) Lipids , vol.36 , pp. 373-378
    • Dell, C.A.1    Likhodii, S.S.2    Musa, K.3    Ryan, M.A.4    Burnham, W.M.5    Cunnane, S.C.6
  • 12
    • 0025328572 scopus 로고
    • A comparison of the effects of linolenic (18:3 omega 3) and docosahexaenoic (22:6 omega 3) acids on phospholipid bilayers
    • Ehringer W, Belcher D, Wassall SR, Stillwell W. (1990) A comparison of the effects of linolenic (18:3 omega 3) and docosahexaenoic (22:6 omega 3) acids on phospholipid bilayers. Chem Phys Lipids 54 : 79 88.
    • (1990) Chem Phys Lipids , vol.54 , pp. 79-88
    • Ehringer, W.1    Belcher, D.2    Wassall, S.R.3    Stillwell, W.4
  • 13
    • 0037465771 scopus 로고    scopus 로고
    • Elevated polyunsaturated fatty acids in blood serum obtained from children on the ketogenic diet
    • Fraser DD, Whiting S, Andrew RD, Macdonald EA, Musa-Veloso K, Cunnane SC. (2003) Elevated polyunsaturated fatty acids in blood serum obtained from children on the ketogenic diet. Neurology 60 : 1026 1029.
    • (2003) Neurology , vol.60 , pp. 1026-1029
    • Fraser, D.D.1    Whiting, S.2    Andrew, R.D.3    MacDonald, E.A.4    Musa-Veloso, K.5    Cunnane, S.C.6
  • 14
    • 0031773486 scopus 로고    scopus 로고
    • The efficacy of the ketogenic diet-1998: A prospective evaluation of intervention in 150 children
    • Freeman JM, Vining EP, Pillas DJ, Pyzik PL, Casey JC, Kelly LM. (1998) The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children. Pediatrics 102 : 1358 1363.
    • (1998) Pediatrics , vol.102 , pp. 1358-1363
    • Freeman, J.M.1    Vining, E.P.2    Pillas, D.J.3    Pyzik, P.L.4    Casey, J.C.5    Kelly, L.M.6
  • 15
    • 0023182457 scopus 로고
    • Relationships between the lipid content and the rheological properties of airway secretions in cystic fibrosis
    • Galabert C, Jacquot J, Zahm JM, Puchelle E. (1987) Relationships between the lipid content and the rheological properties of airway secretions in cystic fibrosis. Clin Chim Acta 164 : 139 149.
    • (1987) Clin Chim Acta , vol.164 , pp. 139-149
    • Galabert, C.1    Jacquot, J.2    Zahm, J.M.3    Puchelle, E.4
  • 16
    • 0038292118 scopus 로고    scopus 로고
    • Essential fatty acids and the brain
    • Haag M. (2003) Essential fatty acids and the brain. Can J Psychiatry 48 : 195 203.
    • (2003) Can J Psychiatry , vol.48 , pp. 195-203
    • Haag, M.1
  • 17
    • 0030756197 scopus 로고    scopus 로고
    • Ketogenic diet: Effects on expression of kindled seizures and behavior in adult rats
    • Hori A, Tandon P, Holmes GL, Stafstrom CE. (1997) Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats. Epilepsia 38 : 750 758.
    • (1997) Epilepsia , vol.38 , pp. 750-758
    • Hori, A.1    Tandon, P.2    Holmes, G.L.3    Stafstrom, C.E.4
  • 18
    • 33749125215 scopus 로고    scopus 로고
    • Biophysical properties of lipids and dynamic membranes
    • Janmey PA, Kinnunen PK. (2006) Biophysical properties of lipids and dynamic membranes. Trends Cell Biol 16 : 538 546.
    • (2006) Trends Cell Biol , vol.16 , pp. 538-546
    • Janmey, P.A.1    Kinnunen, P.K.2
  • 19
    • 0030957326 scopus 로고    scopus 로고
    • Arachidonic acid inhibits transient potassium currents and broadens action potentials during electrographic seizures in hippocampal pyramidal and inhibitory interneurons
    • Keros S, McBain CJ. (1997) Arachidonic acid inhibits transient potassium currents and broadens action potentials during electrographic seizures in hippocampal pyramidal and inhibitory interneurons. J Neurosci 17 : 3476 3487.
    • (1997) J Neurosci , vol.17 , pp. 3476-3487
    • Keros, S.1    McBain, C.J.2
  • 22
    • 0025817126 scopus 로고
    • The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazole seizure models
    • Loscher W, Honack D, Fassbender CP, Nolting B. (1991) The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazole seizure models. Epilepsy Res 8 : 171 189.
    • (1991) Epilepsy Res , vol.8 , pp. 171-189
    • Loscher, W.1    Honack, D.2    Fassbender, C.P.3    Nolting, B.4
  • 23
    • 4243190715 scopus 로고
    • Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol
    • Morrison WR, Smith LM. (1964) Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol. J Lipid Res 5 : 600 608.
    • (1964) J Lipid Res , vol.5 , pp. 600-608
    • Morrison, W.R.1    Smith, L.M.2
  • 25
    • 0021906711 scopus 로고
    • A timed intravenous pentylenetetrazol infusion seizure model for quantitating the anticonvulsant effect of valproic acid in the rat
    • Pollack GM, Shen DD. (1985) A timed intravenous pentylenetetrazol infusion seizure model for quantitating the anticonvulsant effect of valproic acid in the rat. J Pharmacol Methods 13 : 135 146.
    • (1985) J Pharmacol Methods , vol.13 , pp. 135-146
    • Pollack, G.M.1    Shen, D.D.2
  • 27
    • 0242269459 scopus 로고    scopus 로고
    • Anticonvulsant efficiency, behavioral performance and cortisol levels: A comparison of carbamazepine (CBZ) and a fatty acid compound (SR-3)
    • Rabinovitz S, Mostofsky DI, Yehuda S. (2004) Anticonvulsant efficiency, behavioral performance and cortisol levels: a comparison of carbamazepine (CBZ) and a fatty acid compound (SR-3). Psychoneuroendocrinology 29 : 113 124.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 113-124
    • Rabinovitz, S.1    Mostofsky, D.I.2    Yehuda, S.3
  • 28
    • 0001425525 scopus 로고
    • Nutrition
    • In. Baker, H., Lindsey, J., Weisbroth, S. (. Eds). Academic Press, Orlando, FL.
    • Rogers A. (1979) Nutrition. In Baker H, Lindsey J, Weisbroth S. (Eds) The laboratory rat. Academic Press, Orlando, FL.
    • (1979) The Laboratory Rat.
    • Rogers, A.1
  • 29
    • 0036200360 scopus 로고    scopus 로고
    • Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients
    • Schlanger S, Shinitzky M, Yam D. (2002) Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients. Epilepsia 43 : 103 104.
    • (2002) Epilepsia , vol.43 , pp. 103-104
    • Schlanger, S.1    Shinitzky, M.2    Yam, D.3
  • 30
    • 0034913114 scopus 로고    scopus 로고
    • Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain
    • Spector AA. (2001) Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain. J Mol Neurosci 16 : 159 165.
    • (2001) J Mol Neurosci , vol.16 , pp. 159-165
    • Spector, A.A.1
  • 31
    • 0027394324 scopus 로고
    • Docosahexaenoic acid increases permeability of lipid vesicles and tumor cells
    • Stillwell W, Ehringer W, Jenski LJ. (1993) Docosahexaenoic acid increases permeability of lipid vesicles and tumor cells. Lipids 28 : 103 108.
    • (1993) Lipids , vol.28 , pp. 103-108
    • Stillwell, W.1    Ehringer, W.2    Jenski, L.J.3
  • 32
    • 23944442745 scopus 로고    scopus 로고
    • Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats
    • Taha AY, Ryan MA, Cunnane SC. (2005) Despite transient ketosis, the classic high-fat ketogenic diet induces marked changes in fatty acid metabolism in rats. Metabolism 54 : 1127 1132.
    • (2005) Metabolism , vol.54 , pp. 1127-1132
    • Taha, A.Y.1    Ryan, M.A.2    Cunnane, S.C.3
  • 33
    • 33747222482 scopus 로고    scopus 로고
    • Lack of benefit of linoleic and alpha-linolenic polyunsaturated fatty acids on seizure latency, duration, severity or incidence in rats
    • Taha AY, Baghiu BM, Lui R, Nylen K, Ma DW, Burnham WM. (2006) Lack of benefit of linoleic and alpha-linolenic polyunsaturated fatty acids on seizure latency, duration, severity or incidence in rats. Epilepsy Res 71 : 40 46.
    • (2006) Epilepsy Res , vol.71 , pp. 40-46
    • Taha, A.Y.1    Baghiu, B.M.2    Lui, R.3    Nylen, K.4    Ma, D.W.5    Burnham, W.M.6
  • 34
    • 41749121711 scopus 로고    scopus 로고
    • Seizure resistance in fat-1 transgenic mice endogenously synthesizing high levels of omega-3 polyunsaturated fatty acids
    • Taha AY, Huot PS, Reza-Lopez S, Prayitno NR, Kang JX, Burnham WM, Ma DW. (2008) Seizure resistance in fat-1 transgenic mice endogenously synthesizing high levels of omega-3 polyunsaturated fatty acids. J Neurochem 105 : 380 388.
    • (2008) J Neurochem , vol.105 , pp. 380-388
    • Taha, A.Y.1    Huot, P.S.2    Reza-Lopez, S.3    Prayitno, N.R.4    Kang, J.X.5    Burnham, W.M.6    Ma, D.W.7
  • 36
    • 0032877719 scopus 로고    scopus 로고
    • Clinical efficacy of the ketogenic diet
    • Vining EP. (1999) Clinical efficacy of the ketogenic diet. Epilepsy Res 37 : 181 190.
    • (1999) Epilepsy Res , vol.37 , pp. 181-190
    • Vining, E.P.1
  • 37
    • 0032509704 scopus 로고    scopus 로고
    • Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model
    • Voskuyl RA, Vreugdenhil M, Kang JX, Leaf A. (1998) Anticonvulsant effect of polyunsaturated fatty acids in rats, using the cortical stimulation model. Eur J Pharmacol 341 : 145 152.
    • (1998) Eur J Pharmacol , vol.341 , pp. 145-152
    • Voskuyl, R.A.1    Vreugdenhil, M.2    Kang, J.X.3    Leaf, A.4
  • 41
    • 0032845896 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation
    • Xiao Y, Li X. (1999) Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation. Brain Res 846 : 112 121.
    • (1999) Brain Res , vol.846 , pp. 112-121
    • Xiao, Y.1    Li, X.2
  • 42
    • 0028316790 scopus 로고
    • Essential fatty acid preparation (SR-3) raises the seizure threshold in rats
    • Yehuda S, Carasso RL, Mostofsky DI. (1994) Essential fatty acid preparation (SR-3) raises the seizure threshold in rats. Eur J Pharmacol 254 : 193 198.
    • (1994) Eur J Pharmacol , vol.254 , pp. 193-198
    • Yehuda, S.1    Carasso, R.L.2    Mostofsky, D.I.3
  • 43
    • 0030239976 scopus 로고    scopus 로고
    • Essential fatty acid preparation reduces cholesterol and fatty acids in rat cortex
    • Yehuda S, Brandys Y, Blumenfeld A, Mostofsky DI. (1996) Essential fatty acid preparation reduces cholesterol and fatty acids in rat cortex. Int J Neurosci 86 : 249 256.
    • (1996) Int J Neurosci , vol.86 , pp. 249-256
    • Yehuda, S.1    Brandys, Y.2    Blumenfeld, A.3    Mostofsky, D.I.4
  • 45
    • 0033564615 scopus 로고    scopus 로고
    • Essential fatty acids are mediators of brain biochemistry and cognitive functions
    • Yehuda S, Rabinovitz S, Mostofsky DI. (1999) Essential fatty acids are mediators of brain biochemistry and cognitive functions. J Neurosci Res 56 : 565 570.
    • (1999) J Neurosci Res , vol.56 , pp. 565-570
    • Yehuda, S.1    Rabinovitz, S.2    Mostofsky, D.I.3
  • 46
    • 0034237584 scopus 로고    scopus 로고
    • Essential fatty acids and the brain: Possible health implications
    • Youdim KA, Martin A, Joseph JA. (2000) Essential fatty acids and the brain: possible health implications. Int J Dev Neurosci 18 : 383 399.
    • (2000) Int J Dev Neurosci , vol.18 , pp. 383-399
    • Youdim, K.A.1    Martin, A.2    Joseph, J.A.3
  • 47
    • 0033938160 scopus 로고    scopus 로고
    • Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus
    • Young C, Gean PW, Chiou LC, Shen YZ. (2000) Docosahexaenoic acid inhibits synaptic transmission and epileptiform activity in the rat hippocampus. Synapse 37 : 90 94.
    • (2000) Synapse , vol.37 , pp. 90-94
    • Young, C.1    Gean, P.W.2    Chiou, L.C.3    Shen, Y.Z.4
  • 49
    • 0026085199 scopus 로고
    • Interactive effects of dietary (n-3) polyunsaturated fatty acids and chronic ethanol intoxication on synaptic membrane lipid composition and fluidity in rats
    • Zerouga M, Beauge F, Niel E, Durand G, Bourre JM. (1991) Interactive effects of dietary (n-3) polyunsaturated fatty acids and chronic ethanol intoxication on synaptic membrane lipid composition and fluidity in rats. Biochim Biophys Acta 1086 : 295 304.
    • (1991) Biochim Biophys Acta , vol.1086 , pp. 295-304
    • Zerouga, M.1    Beauge, F.2    Niel, E.3    Durand, G.4    Bourre, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.