메뉴 건너뛰기




Volumn 21, Issue 3-5, 1999, Pages 400-406

Path analysis shows that increasing ketogenic ratio, but not β-hydroxybutyrate, elevates seizure threshold in the rat

Author keywords

Epilepsy; Ketogenic diet; Pentylenetetrazole; Rat; Seizure; hydroxybutyrate

Indexed keywords

3 HYDROXYBUTYRIC ACID; CARBOHYDRATE; FAT; PROTEIN;

EID: 0032738404     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000017390     Document Type: Article
Times cited : (46)

References (35)
  • 1
    • 0016332555 scopus 로고
    • An animal model for the ketogenic diet
    • Appleton DB. DeVivo DC (1974): An animal model for the ketogenic diet. Epilepsia 15:211-227.
    • (1974) Epilepsia , vol.15 , pp. 211-227
    • Appleton, D.B.1    DeVivo, D.C.2
  • 3
    • 0032901064 scopus 로고    scopus 로고
    • A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat
    • Bough KJ, Eagles DA (1999): A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. Epilepsia 40:138-143.
    • (1999) Epilepsia , vol.40 , pp. 138-143
    • Bough, K.J.1    Eagles, D.A.2
  • 4
    • 0344683419 scopus 로고    scopus 로고
    • A ketogenic diet has differential effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion
    • in press
    • Bough KJ, Matthews PJ, Eagles DA (1999a): A ketogenic diet has differential effects upon seizures induced by maximal electroshock and by pentylenetetrazole infusion. Epilepsy Res, in press.
    • (1999) Epilepsy Res
    • Bough, K.J.1    Matthews, P.J.2    Eagles, D.A.3
  • 5
    • 0032902642 scopus 로고    scopus 로고
    • Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet
    • Bough KJ, Valiyil R, Han FT, Eagles DA (1999b): Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet. Epilepsy Res 35:21-28.
    • (1999) Epilepsy Res , vol.35 , pp. 21-28
    • Bough, K.J.1    Valiyil, R.2    Han, F.T.3    Eagles, D.A.4
  • 6
    • 0033400976 scopus 로고    scopus 로고
    • Higher ketogenic diet ratios confer protection from seizures without neurotoxicity
    • in press
    • Bough KJ, Yao SG, Eagles DA (1999c): Higher ketogenic diet ratios confer protection from seizures without neurotoxicity. Epilepsy Res, in press.
    • (1999) Epilepsy Res
    • Bough, K.J.1    Yao, S.G.2    Eagles, D.A.3
  • 7
    • 0017177061 scopus 로고
    • Changes during development in transport processes of the blood-brain barrier
    • Cremer JE, Braun LD, Oldendorf WH (1976): Changes during development in transport processes of the blood-brain barrier. Biochim Biophys Acta 448:633-637.
    • (1976) Biochim Biophys Acta , vol.448 , pp. 633-637
    • Cremer, J.E.1    Braun, L.D.2    Oldendorf, W.H.3
  • 8
    • 0017107310 scopus 로고
    • The rate of cerebral utilization of glucose, ketone bodies and oxygen: A comparative in vivo study of infant and adult rats
    • Dahlquist G, Persson B (1976): The rate of cerebral utilization of glucose, ketone bodies and oxygen: A comparative in vivo study of infant and adult rats. Pediatr Res 10:910-917.
    • (1976) Pediatr Res , vol.10 , pp. 910-917
    • Dahlquist, G.1    Persson, B.2
  • 9
    • 0019505898 scopus 로고
    • Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats
    • Davis JD, Wirtshafter D, Asin KE, Brief D (1981): Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats. Science 212:81-83.
    • (1981) Science , vol.212 , pp. 81-83
    • Davis, J.D.1    Wirtshafter, D.2    Asin, K.E.3    Brief, D.4
  • 10
    • 0015849711 scopus 로고
    • Ketotic hypoglycemia and the ketogenic diet
    • DeVivo DC, Pagliara AS, Prensky AL (1973): Ketotic hypoglycemia and the ketogenic diet. Neurology 23:640-649.
    • (1973) Neurology , vol.23 , pp. 640-649
    • DeVivo, D.C.1    Pagliara, A.S.2    Prensky, A.L.3
  • 11
    • 0021131954 scopus 로고
    • Proconvulsant effect of morphine on seizures induced by pentylenetetrazole in the rat
    • Foote F, Gale K (1984): Proconvulsant effect of morphine on seizures induced by pentylenetetrazole in the rat. Eur J Pharmacol 105:179-184.
    • (1984) Eur J Pharmacol , vol.105 , pp. 179-184
    • Foote, F.1    Gale, K.2
  • 13
    • 0031773486 scopus 로고    scopus 로고
    • The efficacy of the ketogenic diet - 1998: A prospective evaluation of intervention in 150 children
    • Freeman JM, Vining EPG, Pillas DJ, Pyzik PL, Casey JC, Kelly MT (1998): The efficacy of the ketogenic diet - 1998: A prospective evaluation of intervention in 150 children. Pediatrics 102: 1358-1363.
    • (1998) Pediatrics , vol.102 , pp. 1358-1363
    • Freeman, J.M.1    Vining, E.P.G.2    Pillas, D.J.3    Pyzik, P.L.4    Casey, J.C.5    Kelly, M.T.6
  • 14
    • 0015020675 scopus 로고
    • Ketone-body utilization by adult and suckling rat brain in vivo
    • Hawkins RA, Williamson DH, Krebs HA (1971): Ketone-body utilization by adult and suckling rat brain in vivo. Biochem J 122:13-18.
    • (1971) Biochem J , vol.122 , pp. 13-18
    • Hawkins, R.A.1    Williamson, D.H.2    Krebs, H.A.3
  • 15
    • 0001490624 scopus 로고
    • Eight years' experience with the ketogenic diet in the treatment of epilepsy
    • Helmholz HF, Keith HM (1930): Eight years' experience with the ketogenic diet in the treatment of epilepsy. JAMA 95:707-709.
    • (1930) JAMA , vol.95 , pp. 707-709
    • Helmholz, H.F.1    Keith, H.M.2
  • 16
    • 0030756197 scopus 로고    scopus 로고
    • Ketogenic diet: Effects on expression of kindled seizures and behavior in adult rats
    • Hori A, Tandon P, Holmes GL, Stafstrom CF (1997): Ketogenic diet: Effects on expression of kindled seizures and behavior in adult rats. Epilepsia 38:750-758.
    • (1997) Epilepsia , vol.38 , pp. 750-758
    • Hori, A.1    Tandon, P.2    Holmes, G.L.3    Stafstrom, C.F.4
  • 17
    • 0017143254 scopus 로고
    • Ketonemia and seizures: Metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy
    • Huttenlocher PR (1976): Ketonemia and seizures: Metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy. Pediatr Res 10:536-540.
    • (1976) Pediatr Res , vol.10 , pp. 536-540
    • Huttenlocher, P.R.1
  • 18
    • 0015150112 scopus 로고
    • Medium-chain triglycerides as a therapy for intractable childhood epilepsy
    • Huttenlocher PR, Wilbourn AJ, Signore JM (1971): Medium-chain triglycerides as a therapy for intractable childhood epilepsy. Neurology 21:1097-1103.
    • (1971) Neurology , vol.21 , pp. 1097-1103
    • Huttenlocher, P.R.1    Wilbourn, A.J.2    Signore, J.M.3
  • 19
    • 0027097935 scopus 로고
    • Efficacy of the ketogenic diet for intractable seizure disorders: Review of 58 cases
    • Kinsman SL, Vining EPG, Quaskey SA, Mellits ED, Freeman JM (1992): Efficacy of the ketogenic diet for intractable seizure disorders: Review of 58 cases. Epilepsia 33:1132-1136.
    • (1992) Epilepsia , vol.33 , pp. 1132-1136
    • Kinsman, S.L.1    Vining, E.P.G.2    Quaskey, S.A.3    Mellits, E.D.4    Freeman, J.M.5
  • 20
    • 0003612066 scopus 로고
    • Comprehensive Management of Epilepsy in Infancy
    • Springfield, Thomas
    • Livingston S (1972): Comprehensive Management of Epilepsy in Infancy, Childhood and Adolescence. Springfield, Thomas.
    • (1972) Childhood and Adolescence
    • Livingston, S.1
  • 21
    • 0000856564 scopus 로고
    • Mechanism of anticonvulsant action of ketogenic diet
    • Millichap JG, Jones JD, Rudis BP (1964): Mechanism of anticonvulsant action of ketogenic diet. Am J Dis Child 107:593-604.
    • (1964) Am J Dis Child , vol.107 , pp. 593-604
    • Millichap, J.G.1    Jones, J.D.2    Rudis, B.P.3
  • 22
    • 0020591265 scopus 로고
    • Effects of ketogenic diet on electroconvulsive threshold and brain contents of adenosine nucleotides
    • Nakazawa M, Kodama S, Matsuo T (1983): Effects of ketogenic diet on electroconvulsive threshold and brain contents of adenosine nucleotides. Brain Dev 5:375-380.
    • (1983) Brain Dev , vol.5 , pp. 375-380
    • Nakazawa, M.1    Kodama, S.2    Matsuo, T.3
  • 23
    • 0030755496 scopus 로고    scopus 로고
    • The ketogenic diet revisited: Back to the future
    • Nordli DR, DeVivo DC (1997): The ketogenic diet revisited: Back to the future. Epilepsia 38:743-749.
    • (1997) Epilepsia , vol.38 , pp. 743-749
    • Nordli, D.R.1    DeVivo, D.C.2
  • 24
    • 0021270165 scopus 로고
    • Effect of ketogenic diet on convulsive threshold and brain monoamine levels in young mice
    • Otani K, Yamatodani A, Wada H, Mimaki T, Yabuuchi H (1984): Effect of ketogenic diet on convulsive threshold and brain monoamine levels in young mice. No Tu Hattatsu 16:196-204.
    • (1984) No Tu Hattatsu , vol.16 , pp. 196-204
    • Otani, K.1    Yamatodani, A.2    Wada, H.3    Mimaki, T.4    Yabuuchi, H.5
  • 25
    • 0014970829 scopus 로고
    • Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats
    • Page MA, Krebs HA, Williamson DH (1971): Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats. Biochem J 121:49-53.
    • (1971) Biochem J , vol.121 , pp. 49-53
    • Page, M.A.1    Krebs, H.A.2    Williamson, D.H.3
  • 26
    • 0001434053 scopus 로고
    • The ketogenic diet in epilepsy
    • Peterman MG (1925): The ketogenic diet in epilepsy. JAMA 84:1979-1983.
    • (1925) JAMA , vol.84 , pp. 1979-1983
    • Peterman, M.G.1
  • 27
    • 0021906711 scopus 로고
    • A timed intravenous pentylenetetrazole infusion seizure model for quantitating the anticonvulsant effect of valproic acid in the rat
    • Pollack GM, Shen DD (1985): A timed intravenous pentylenetetrazole infusion seizure model for quantitating the anticonvulsant effect of valproic acid in the rat. J Pharmacol Methods 13: 135-146.
    • (1985) J Pharmacol Methods , vol.13 , pp. 135-146
    • Pollack, G.M.1    Shen, D.D.2
  • 28
    • 0029982549 scopus 로고    scopus 로고
    • Alternative epilepsy therapies: The ketogenic diet, immunoglobulins and steroids
    • Prasad AN, Stafstrom CF, Holmes GL (1996): Alternative epilepsy therapies: The ketogenic diet, immunoglobulins and steroids. Epilepsia 37(suppl 1):S81-S95.
    • (1996) Epilepsia , vol.37 , Issue.1 SUPPL.
    • Prasad, A.N.1    Stafstrom, C.F.2    Holmes, G.L.3
  • 29
    • 0345114368 scopus 로고
    • Baker HJ, Lindsey JR, Weisbroth SH (eds): The Laboratory Rat. Orlando, Academic Press
    • Rogers AE (1979): Nutrition; in Baker HJ, Lindsey JR, Weisbroth SH (eds): The Laboratory Rat. Orlando, Academic Press, vol I.
    • (1979) Nutrition , vol.1
    • Rogers, A.E.1
  • 30
    • 0024541972 scopus 로고
    • Metabolic effects of three ketogenic diets in the treatment of severe epilepsy
    • Schwartz RM, Boyes S, Aynsley-Green A (1989): Metabolic effects of three ketogenic diets in the treatment of severe epilepsy. Dev Med Child Neurol 31:152-160.
    • (1989) Dev Med Child Neurol , vol.31 , pp. 152-160
    • Schwartz, R.M.1    Boyes, S.2    Aynsley-Green, A.3
  • 32
    • 0015295507 scopus 로고
    • Anticonvulsant properties of the ketogenic diet in mice
    • Uhlemann ER, Neims AH (1972): Anticonvulsant properties of the ketogenic diet in mice. J Pharmacol Exp Ther 180:231-238.
    • (1972) J Pharmacol Exp Ther , vol.180 , pp. 231-238
    • Uhlemann, E.R.1    Neims, A.H.2
  • 33
    • 0002701539 scopus 로고    scopus 로고
    • The Ketogenic Diet
    • Engel J, Pedley TA (eds): Philadelphia, Lippincott-Raven Publishers
    • Vining EPG (1997): The Ketogenic Diet; in Engel J, Pedley TA (eds): Epilepsy: A Comprehensive Textbook. Philadelphia, Lippincott-Raven Publishers, vol II.
    • (1997) Epilepsy: A Comprehensive Textbook , vol.2
    • Vining, E.P.G.1
  • 34
    • 0001544644 scopus 로고
    • The effects of ketonemia on the course of epilepsy
    • Wilder RM (1921): The effects of ketonemia on the course of epilepsy. Mayo Clin Bull 2:307-308.
    • (1921) Mayo Clin Bull , vol.2 , pp. 307-308
    • Wilder, R.M.1
  • 35
    • 0001530736 scopus 로고
    • Estrous and circadian periodicity and electroshock convulsion in rats
    • Woolley DE, Timiras PS (1962): Estrous and circadian periodicity and electroshock convulsion in rats. Am J Physiol 202:379-382.
    • (1962) Am J Physiol , vol.202 , pp. 379-382
    • Woolley, D.E.1    Timiras, P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.