메뉴 건너뛰기




Volumn 14, Issue 33, 2008, Pages 5162-5175

Roscovitine synergizes with conventional chemo-therapeutic drugs to induce efficient apoptosis of human colorectal cancer cells

Author keywords

Apoptosis; Cell cycle; Chemosensitization; Cyclin dependent kinase inhibition; Human colorectal cancer cell lines; Synergy

Indexed keywords

DOXORUBICIN; FLUOROURACIL; PACLITAXEL; ROSCOVITINE; VINBLASTINE; ANTINEOPLASTIC AGENT; PURINE DERIVATIVE;

EID: 58149237962     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.5162     Document Type: Article
Times cited : (21)

References (39)
  • 2
    • 0036901957 scopus 로고    scopus 로고
    • Cyclin dependent kinases and cell cycle control (nobel lecture)
    • Nurse P. Cyclin dependent kinases and cell cycle control (nobel lecture). Chembiochem 2002; 3: 596-603
    • (2002) Chembiochem , vol.3 , pp. 596-603
    • Nurse, P.1
  • 3
    • 0029921317 scopus 로고    scopus 로고
    • Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
    • Hall M, Peters G. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv Cancer Res 1996; 68: 67-108
    • (1996) Adv Cancer Res , vol.68 , pp. 67-108
    • Hall, M.1    Peters, G.2
  • 4
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam SW, Lavin P, Fiorentino M, Draetta GF, Jessup JM, Pagano M. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997; 3: 231-234
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3    Lavin, P.4    Fiorentino, M.5    Draetta, G.F.6    Jessup, J.M.7    Pagano, M.8
  • 5
    • 28144434721 scopus 로고    scopus 로고
    • Roscovitine modulates DNA repair and senescence: Implications for combination chemotherapy
    • Crescenzi E, Palumbo G, Brady HJ. Roscovitine modulates DNA repair and senescence: implications for combination chemotherapy. Clin Cancer Res 2005; 11: 8158-8171
    • (2005) Clin Cancer Res , vol.11 , pp. 8158-8171
    • Crescenzi, E.1    Palumbo, G.2    Brady, H.J.3
  • 6
    • 0029417882 scopus 로고
    • Chemical inhibitors of cyclin-dependent kinases
    • Meijer L. Chemical inhibitors of cyclin-dependent kinases. Prog Cell Cycle Res 1995; 1: 351-363
    • (1995) Prog Cell Cycle Res , vol.1 , pp. 351-363
    • Meijer, L.1
  • 7
    • 0344809977 scopus 로고    scopus 로고
    • ATP-site directed inhibitors of cyclin-dependent kinases
    • Gray N, Detivaud L, Doerig C, Meijer L. ATP-site directed inhibitors of cyclin-dependent kinases. Curr Med Chem 1999; 6: 859-875
    • (1999) Curr Med Chem , vol.6 , pp. 859-875
    • Gray, N.1    Detivaud, L.2    Doerig, C.3    Meijer, L.4
  • 9
    • 0034702266 scopus 로고    scopus 로고
    • Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines
    • Edamatsu H, Gau CL, Nemoto T, Guo L, Tamanoi F. Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines. Oncogene 2000; 19: 3059-3068
    • (2000) Oncogene , vol.19 , pp. 3059-3068
    • Edamatsu, H.1    Gau, C.L.2    Nemoto, T.3    Guo, L.4    Tamanoi, F.5
  • 10
    • 0033561531 scopus 로고    scopus 로고
    • Roscovitine induces cell death and morphological changes indicative of apoptosis in MDA-MB-231 breast cancer cells
    • Mgbonyebi OP, Russo J, Russo IH. Roscovitine induces cell death and morphological changes indicative of apoptosis in MDA-MB-231 breast cancer cells. Cancer Res 1999; 59: 1903-1910
    • (1999) Cancer Res , vol.59 , pp. 1903-1910
    • Mgbonyebi, O.P.1    Russo, J.2    Russo, I.H.3
  • 11
    • 0031028163 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases by purine analogues: Crystal structure of human cdk2 complexed with roscovitine
    • De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur J Biochem 1997; 243: 518-526
    • (1997) Eur J Biochem , vol.243 , pp. 518-526
    • De Azevedo, W.F.1    Leclerc, S.2    Meijer, L.3    Havlicek, L.4    Strnad, M.5    Kim, S.H.6
  • 12
    • 1542283682 scopus 로고    scopus 로고
    • Antisense oligodeoxynucleotide directed against c-myb has anticancer activity and potentiates the antiproliferative effect of conventional anticancer drugs acting by different mechanisms in human colorectal cancer cells
    • Abaza MS, Al-Attiyah RJ, Al-Saffar AM, Al-Sawan SM, Moussa NM. Antisense oligodeoxynucleotide directed against c-myb has anticancer activity and potentiates the antiproliferative effect of conventional anticancer drugs acting by different mechanisms in human colorectal cancer cells. Tumour Biol 2003; 24: 241-257
    • (2003) Tumour Biol , vol.24 , pp. 241-257
    • Abaza, M.S.1    Al-Attiyah, R.J.2    Al-Saffar, A.M.3    Al-Sawan, S.M.4    Moussa, N.M.5
  • 13
    • 0035669352 scopus 로고    scopus 로고
    • In vitro inhibition of head and neck cancer-cell growth by human recombinant interferon-alpha and 13-cis retinoic acid
    • Lam PK, To EW, Chan ES, Liew CT, Lung IW, King WK. In vitro inhibition of head and neck cancer-cell growth by human recombinant interferon-alpha and 13-cis retinoic acid. Br J Biomed Sci 2001; 58: 226-229
    • (2001) Br J Biomed Sci , vol.58 , pp. 226-229
    • Lam, P.K.1    To, E.W.2    Chan, E.S.3    Liew, C.T.4    Lung, I.W.5    King, W.K.6
  • 15
    • 0030997896 scopus 로고    scopus 로고
    • Evolving strategies of cytotoxic chemotherapy for advanced prostate cancer
    • Raghavan D, Koczwara B, Javle M. Evolving strategies of cytotoxic chemotherapy for advanced prostate cancer. Eur J Cancer 1997; 33: 566-574
    • (1997) Eur J Cancer , vol.33 , pp. 566-574
    • Raghavan, D.1    Koczwara, B.2    Javle, M.3
  • 17
    • 0035011890 scopus 로고    scopus 로고
    • Randomized phase 2 trial of ketoconazole and ketoconazole/doxorubicin in androgen independent prostate cancer
    • Millikan R, Baez L, Banerjee T, Wade J, Edwards K, Winn R, Smith TL, Logothetis C. Randomized phase 2 trial of ketoconazole and ketoconazole/doxorubicin in androgen independent prostate cancer. Urol Oncol 2001; 6: 111-115
    • (2001) Urol Oncol , vol.6 , pp. 111-115
    • Millikan, R.1    Baez, L.2    Banerjee, T.3    Wade, J.4    Edwards, K.5    Winn, R.6    Smith, T.L.7    Logothetis, C.8
  • 18
    • 0037870053 scopus 로고    scopus 로고
    • Flavopiridol inversely affects p21(WAF1/CIP1) and p53 and protects p21-sensitive cells from paclitaxel
    • Blagosklonny MV, Darzynkiewicz Z, Figg WD. Flavopiridol inversely affects p21(WAF1/CIP1) and p53 and protects p21-sensitive cells from paclitaxel. Cancer Biol Ther 2002; 1: 420-425
    • (2002) Cancer Biol Ther , vol.1 , pp. 420-425
    • Blagosklonny, M.V.1    Darzynkiewicz, Z.2    Figg, W.D.3
  • 19
    • 0033539933 scopus 로고    scopus 로고
    • Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells
    • David-Pfeuty T. Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells. Oncogene 1999; 18: 7409-7422
    • (1999) Oncogene , vol.18 , pp. 7409-7422
    • David-Pfeuty, T.1
  • 20
    • 0035921777 scopus 로고    scopus 로고
    • Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells
    • David-Pfeuty T, Nouvian-Dooghe Y, Sirri V, Roussel P, Hernandez-Verdun D. Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells. Oncogene 2001; 20: 5951-5963
    • (2001) Oncogene , vol.20 , pp. 5951-5963
    • David-Pfeuty, T.1    Nouvian-Dooghe, Y.2    Sirri, V.3    Roussel, P.4    Hernandez-Verdun, D.5
  • 22
    • 0041622837 scopus 로고    scopus 로고
    • Rapid onset of nucleolar disintegration preceding cell cycle arrest in roscovitine-induced apoptosis of human MCF-7 breast cancer cells
    • Wojciechowski J, Horky M, Gueorguieva M, Wesierska-Gadek J. Rapid onset of nucleolar disintegration preceding cell cycle arrest in roscovitine-induced apoptosis of human MCF-7 breast cancer cells. Int J Cancer 2003; 106: 486-495
    • (2003) Int J Cancer , vol.106 , pp. 486-495
    • Wojciechowski, J.1    Horky, M.2    Gueorguieva, M.3    Wesierska-Gadek, J.4
  • 23
    • 0033561531 scopus 로고    scopus 로고
    • Roscovitine induces cell death and morphological changes indicative of apoptosis in MDA-MB-231 breast cancer cells
    • Mgbonyebi OP, Russo J, Russo IH. Roscovitine induces cell death and morphological changes indicative of apoptosis in MDA-MB-231 breast cancer cells. Cancer Res 1999; 59: 1903-1910
    • (1999) Cancer Res , vol.59 , pp. 1903-1910
    • Mgbonyebi, O.P.1    Russo, J.2    Russo, I.H.3
  • 25
    • 0036653127 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor (roscovitine) suppresses growth and induces apoptosis by regulating Bcl-x in head and neck squamous cell carcinoma cells
    • Mihara M, Shintani S, Kiyota A, Matsumura T, Wong DT. Cyclin-dependent kinase inhibitor (roscovitine) suppresses growth and induces apoptosis by regulating Bcl-x in head and neck squamous cell carcinoma cells. Int J Oncol 2002; 21: 95-101
    • (2002) Int J Oncol , vol.21 , pp. 95-101
    • Mihara, M.1    Shintani, S.2    Kiyota, A.3    Matsumura, T.4    Wong, D.T.5
  • 27
    • 0027242121 scopus 로고
    • Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands
    • Haimovich B, Lipfert L, Brugge JS, Shattil SJ. Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands. J Biol Chem 1993; 268: 15868-15877
    • (1993) J Biol Chem , vol.268 , pp. 15868-15877
    • Haimovich, B.1    Lipfert, L.2    Brugge, J.S.3    Shattil, S.J.4
  • 28
    • 0031050651 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance
    • Leventhal PS, Shelden EA, Kim B, Feldman EL. Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance. J Biol Chem 1997; 272: 5214-5218
    • (1997) J Biol Chem , vol.272 , pp. 5214-5218
    • Leventhal, P.S.1    Shelden, E.A.2    Kim, B.3    Feldman, E.L.4
  • 29
    • 0031923446 scopus 로고    scopus 로고
    • Alterations in focal adhesion and cytoskeletal proteins during apoptosis
    • Marushige Y, Marushige K. Alterations in focal adhesion and cytoskeletal proteins during apoptosis. Anticancer Res 1998; 18: 301-307
    • (1998) Anticancer Res , vol.18 , pp. 301-307
    • Marushige, Y.1    Marushige, K.2
  • 30
    • 0031845562 scopus 로고    scopus 로고
    • Modulation of apoptotic cell death by extracellular matrix proteins and a fibronectin-derived antiadhesive peptide
    • Fukai F, Mashimo M, Akiyama K, Goto T, Tanuma S, Katayama T. Modulation of apoptotic cell death by extracellular matrix proteins and a fibronectin-derived antiadhesive peptide. Exp Cell Res 1998; 242: 92-99
    • (1998) Exp Cell Res , vol.242 , pp. 92-99
    • Fukai, F.1    Mashimo, M.2    Akiyama, K.3    Goto, T.4    Tanuma, S.5    Katayama, T.6
  • 31
    • 0028057613 scopus 로고
    • Disruption of epithelial cell-matrix interactions induces apoptosis
    • Frisch SM, Francis H. Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 1994; 124: 619-626
    • (1994) J Cell Biol , vol.124 , pp. 619-626
    • Frisch, S.M.1    Francis, H.2
  • 33
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 1998; 279: 509-514
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 34
    • 29844452101 scopus 로고    scopus 로고
    • Dual action of the inhibitors of cyclin-dependent kinases: Targeting of the cell-cycle progression and activation of wild-type p53 protein
    • Wesierska-Gadek J, Schmid G. Dual action of the inhibitors of cyclin-dependent kinases: targeting of the cell-cycle progression and activation of wild-type p53 protein. Expert Opin Investig Drugs 2006; 15: 23-38
    • (2006) Expert Opin Investig Drugs , vol.15 , pp. 23-38
    • Wesierska-Gadek, J.1    Schmid, G.2
  • 35
    • 0036261707 scopus 로고    scopus 로고
    • Sensing and repairing DNA double-strand breaks
    • Jackson SP. Sensing and repairing DNA double-strand breaks. Carcinogenesis 2002; 23: 687-696
    • (2002) Carcinogenesis , vol.23 , pp. 687-696
    • Jackson, S.P.1
  • 37
    • 0034745051 scopus 로고    scopus 로고
    • S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells
    • Hu B, Mitra J, van den Heuvel S, Enders GH. S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells. Mol Cell Biol 2001; 21: 2755-2766
    • (2001) Mol Cell Biol , vol.21 , pp. 2755-2766
    • Hu, B.1    Mitra, J.2    van den Heuvel, S.3    Enders, G.H.4
  • 39
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • Aylon Y, Liefshitz B, Kupiec M. The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J 2004; 23: 4868-4875
    • (2004) EMBO J , vol.23 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.