Rapid onset of nucleolar disintegration preceding cell cycle arrest in roscovitine-induced apoptosis of human MCF-7 breast cancer cells

International Journal of Cancer

Volumn 106, Issue 4, 2003, Pages 486-495

  Wojciechowski, Jacek ^a   Horky, Marcel ^b   Gueorguieva, Marieta ^a   Wȩsierska Ga̧dek, Józefa ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Activation of caspases; Activation of p53; Cell cycle; DNA replication; G2 M arrest; p53 half life

Indexed keywords

ANNEXIN; CASPASE; CISPLATIN; DNA FRAGMENT; HISTONE; NUCLEOLIN; PROTEIN P53; ROSCOVITINE;

ACETYLATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CELL CYCLE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL STRUCTURE; CONTROLLED STUDY; DNA REPLICATION; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MITOSIS; NICK END LABELING; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ACETYLATION; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CASPASES; CELL CYCLE; CELL FRACTIONATION; CELL NUCLEOLUS; CELL SIZE; CYCLIN-DEPENDENT KINASES; ENZYME ACTIVATION; HISTONES; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; NEOPLASM PROTEINS; NUCLEOLUS ORGANIZER REGION; PHOSPHOPROTEINS; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PURINES; RNA-BINDING PROTEINS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0041622837     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11290     Document Type: Article

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