Interleukin-10 is a growth factor for human myeloma cells by induction of an oncostatin M autocrine loop

Blood

Volumn 88, Issue 10, 1996, Pages 3972-3986

  Gu, Zong Jiang ^b   Costes, Valérie ^b   Lu, Zhao Yang ^b   Zhang, Xue Guang ^b   Pitard, Vincent ^b   Moreau, Jean François ^b   Bataille, Régis ^b   Wijdenes, John ^b   Rossi, Jean François ^b   Klein, Bernard ^a  

^a CNRS   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; GLYCOPROTEIN GP 130; GROWTH FACTOR; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; LEUKEMIA INHIBITORY FACTOR; MONOCLONAL ANTIBODY; ONCOSTATIN M;

ADULT; ARTICLE; BLOOD SAMPLING; BONE MARROW; CANCER CELL CULTURE; CANCER GROWTH; CELL LINE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MULTIPLE MYELOMA; MYELOMA CELL; PRIORITY JOURNAL; RECEPTOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 10544241191     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.10.3972.bloodjournal88103972     Document Type: Article

References (39)

1. Kishimoto T, Akira S, Narazaki M, Taga T: Interleukin-6 family of cytokines and gp130. Blood 86:1243, 1995
2. Pennica D,King KL, Shaw KJ, Luis E, Rullamas J, Luoh SM, Darbonne WC, Knutzon DS, Yen R, Chien KR, Baker JB, Wood WI: Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc Natl Acad Sci USA 92:1142, 1995
3. Pennica D, Shaw KJ, Swanson TA, Moore MW, Shelton DL, Zioncheck KA, Rosenthal A, Taga T, Paoni NF, Wood WI: Cardiotrophin- 1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J Biol Chem 270:10915, 1995
4. Murakami M, Hibi M, Nakagawa N, Nakagawa T, Yasukawa K, Yamanishi K, Taga T, Kishimoto T: IL-6-induced homodimerization of gp 130 and associated activation of a tyrosine kinase. Science 260:1808, 1993
5. Hilton DJ, Hilton AA, Raicevic A, Rakar S, Harrison Smith M, Gough NM, Begley CG, Metcalf D, Nicola NA, Willson TA: Cloning of a murine IL-11 receptor alpha-chain: Requirement for gp130 for high affinity binding and signal transduction. EMBO J 13 :4765, 1994
6. Truitt KE, Hicks CM, Imboden JB: Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells. J Exp Med 179:1071, 1994
7. Gearing DP, Comeau MR, Friend DJ, Gimpel SD, Thut CJ. McGourty J, Brasher KK, King JA, Gillis S, Mosley B, Ziegler SF, Cosman D: The IL-6 signal transducer gp130: An oncostatin M receptor and affinity convener for the LIF receptor. Science 255:1434, 1992
8. Davis S, Aldrich TH, Stahl N, Pan L, Taga T, Kishimoto T, Ip NY, Yancopoulos GD: LIFRβ and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260:1805, 1993
9. Murakami-Mori K, Taga T, Kishimoto T, Nakamura S: AIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. J Clin Invest 96:1319, 1995
10. Klein B, Zhang XG, Lu ZY, Bataille R: Interleukin-6 in human multiple myeloma. Blood 85:863, 1995
11. Zhang XG, Gaillard JP, Robillard N, Lu ZY, Gu ZJ, Jourdan M, Boiron JM, Bataille R, Klein B: Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma. Blood 83:3654, 1994
12. Degrassi A, Hibert DM, Rudikoff S, Anderson AO, Potter M, Coon HG: In vitro culture of primary plasmacytomas requires stromal cell feeder layers. Proc Natl Acad Sci USA 90:2060, 1993
13. Chauhan D, Kharbanda SM, Ogata A, Urashima M, Frank D, Malik N, Kufe DW, Anderson KC: Oncostatin M induces association of Grb2 with Janus kinase JAK2 in multiple myeloma cells. J Exp Med 182:1801, 1995
14. Nishimoto N, Ogata A, Shima Y, Tani Y, Ogawa H, Nakagawa M, Sugiyama H, Yoshizaki K, Kishimoto T: Oncostatin M, leukemia inhibitory factor, and interleukin-6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130. J Exp Med 179:1343, 1994
15. Zhang XG, Gu ZJ, Lu ZY, Yasukawa K, Yancopoulos GD, Turner K, Shoyab M, Taga T. Kishimoto T, Bataille R, Klein B: Ciliary neurotropic factor, interleukin 11, leukemia inhibitory factor, and oncostatin M are growth factors for human myeloma cell lines using the interleukin 6 signal transducer gp130. J Exp Med 179:1337, 1994
16. Lu ZY, Gu ZJ, Zhang XG, Wijdenes J, Neddermann P, Rossi JF, Klein B: Interleukin-10 induces interleukin-11 responsiveness in human myeloma cell lines. FEBS Lett 377:515, 1995
17. Lu ZY, Zhang XG, Wijdenes J, Morel-Fournier B, Harousseau JL, Bataille R, Rossi JF, Klein B: Interleukin-10 is a growth factor for human myeloma cells. Blood 85:2521, 1995
18. Liu Y, Wei SH, Ho AS, de-Waal-Malefyt R, Moore KW: Expression cloning and characterization of a human IL-10 receptor. J Immunol 152:1821, 1994
19. Wijdenes J, Vooijs WC, Clement C, Post J, Morard F, Vita N, Laurent P, Sun RX, Klein B, Dore JM: A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1. Br J Haematol (in press)
20. Lane TA, Law P, Maruyama M, Young D. Burgess J, Mullen M, Mealiffe M, Terstappen L, Hardwick A, Moubayed M. Oldham F, Corringham RET, Ho AD: Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) of G-CSF: Potential role in allogeneic marrow transplantation. Blood 85:275, 1995
21. Klein B, Zhang XG, Jourdan M, Content J, Houssiau F, Aarden L, Piechaczyk M, Bataille R: Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6. Blood 73:517, 1989
22. Bataille R, Jourdan M, Zhang XG, Klein B: Serum levels of interleukin-6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias. J Clin Invest 84:2008, 1989
23. Masood R, Zhang Y, Bond MW, Scadden DT, Moudgil T, Law RE, Kaplan MH, Jung B, Espina BM, Lunardi Iskandar Y, Levine AM, Parkash SG: Interleukin-10 is an autocrine growth factor for acquired immunodeficiency syndrome-related B-cell lymphoma. Blood 85:3423, 1995
24. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning. A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
25. Lu ZY,Zhang XG, Gu ZJ, Yasukawa K, Amiot M, Etrillard M, Bataille R, Klein B: A highly sensitive quantitative bioassay for human interleukin-11. J Immunol Methods 173:19, 1994
26. Gu ZJ, Wijdenes J,Zhang XG, Hallet MM, Clement C, Klein B: Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M. J Immunol Methods 190:21. 1996
27. Howard M, O'garra A, Ishida H, Malefyt R, de Vries J: Biological properties of IL-10. J Clin Immunol 12:239, 1992
28. Klein B: Cytokine, cytokine receptors, transduction signals, and oncogenes in human multiple myeloma. Semin Hematol 32:4, 1995
29. Gaillard JP, Bataille R, Brailly H, Zuber C, Yasukawa K, Attal M, Maruo N, Taga T, Kishimoto T, Klein B: Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy. Eur J Immunol 23:820, 1993
30. Yasukawa K, Saito T, Fukunaga T, Sekimori Y, Koishihara Y, Fukui H, Ohsugi Y, Matsuda T, Yawata H, Hirano T, Taga T, Kishimoto T: Purification and characterization of soluble human IL-6 receptor expressed in CHO cells. J Biol Chem 198:673, 1990
31. Klein B, Wijdenes J, Zhang XG, Jourdan M, Boiron JM, Liautard J, Merlin M, Clement C, Morel-Fournier B, Lu ZY, Mannoni P, Sany J, Bataille R: Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia. Blood 78:1198, 1991
32. Bataille R, Barlogie B, Lu ZY, Rossi JF, Lavabre-Bertrand T, Beck T, Wijdenes J, Brochier J, Klein B: Biologic effects of anti-interleukin-6 (IL-6) murine monoclonal antibody in advanced multiple myeloma. Blood 86:685, 1995
33. Lu ZY, Brailly H, Wijdenes J, Bataille R, Rossi JF, Klein B: Measurement of whole body IL-6 production: Prediction of the efficacy of anti-IL-6 treatments. Blood 86:3123, 1995
34. Montero-Julian FA, Klein B, Gautherot E. Brailly H: Pharmacokinetic study of anti-IL-6 therapy with monoclonal antibodies: Enhancement of IL-6 clearance by a cocktail of anti - IL-6 antibodies. Blood 85:917, 1995
35. Burdin N, Van Kooten C, Galibert L, Abrams JS, Wijdenes J, Banchereau J, Rousset F: Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 154:2533, 1995
36. Rousset F, Garcia E, Defrance T, Péronne C, Vezzio N, Hsu DH, Kastelein R, Moore KW, Banchereau J: Interleukin-10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 89:1890, 1992
37. Vernino L, McAnally LM, Ramberg J, Lipsky PE: Generation of nondividing high rate Ig-secreting plasma cells in cultures of human B cells stimulated with anti-CD3-activated T cells. J Immunol 148:404, 1992
38. Tucci A, James H, Chicheportiche R, Bonnefoy JY, Dayer JM, Zubler RH: Effects of eleven cytokines and of IL-1 and tumor necrosis factor inhibitors in a human B cell assay. J Immunol 148:2778, 1992
39. Arpin C, Dechanet J, Van Kooten C, Merville P, Grouard G, Briere F, Banchereau J, Liu YJ: Generation of memory B cells and plasma cells in vitro. Science 268:720, 1995