Establishment of a βB2 crystallin gene knockout mice model

Academic Journal of Second Military Medical University

Volumn 27, Issue 11, 2006, Pages 1246-1248

  Zhang, Jun ^a   Huang, Cai Guo ^b   Li, Wen Jie ^a   Weng, Wei ^c   Wang, Jia Qi ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c inGenious Targeting Laboratory Inc   (United States)

Author keywords

Beta crystallin; Mice, gene knockout

Indexed keywords

BETA B2 CRYSTALLIN; BETA CRYSTALLIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE TARGETING; GENE VECTOR; GENOTYPE; KNOCKOUT MOUSE; LABORATORY; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; WESTERN BLOTTING;

EID: 37849185320     PISSN: 0258879X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Boyle DL, Takemoto L, Brady JP, et al. Morphological characterization of the Alpha A- and Alpha B crystallin double knockout mouse lens[J]. BMC Ophthalmol, 2003, 3:3.
2. Brady JP, Garland D, Duglas-Tabor Y, et al. Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B crystallin[J]. Proc Natl Acad Sci USA, 1997, 94: 884-889.
3. Brady JP, Garland DL, Green DE, et al. Alpha B-crystallin in lens development and muscle integrity: a gene knockout approach[J]. Invest Ophthalmol Vis Sci,2001,42: 2924-2934.
4. Chinese source. 2004, 20:1905-1907.
5. Chinese source. 2004, 20:22-26.
6. Bloemendal H, de Jong W, Jaenicke R, et al. Ageing and vision: structure, stability and function of lens crystallins[J]. Prog Biophys Mol Biol, 2004, 86: 407-485.